Disruption of the sarcoglycan-sarcospan complex in vascular smooth muscle: a novel mechanism for cardiomyopathy and muscular dystrophy.

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Cell

• Publication date

  1999-08-20

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0092-8674(00)81975-3PMID 10481911
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Enteroviral protease 2A cleaves dystrophin: Evidence of cytoskeletal disruption in an acquired cardiomyopathy

  1999cited by this paper
• ε-Sarcoglycan Replaces α-Sarcoglycan in Smooth Muscle to Form a Unique Dystrophin-Glycoprotein Complex*

  1999cited by this paper
• Delineation of genomic deletion in cardiomyopathic hamster

  1999influential reference
• Mutations in the gene encoding lamin A/C cause autosomal dominant Emery-Dreifuss muscular dystrophy

  1999cited by this paper
• Membrane Targeting and Stabilization of Sarcospan Is Mediated by the Sarcoglycan Subcomplex

  1999influential reference
• Heart involvement in muscular dystrophies due to sarcoglycan gene mutations

  1999cited by this paper
• The role of cytoskeletal proteins in cardiomyopathies.

  1998cited by this paper
• γ-Sarcoglycan Deficiency Leads to Muscle Membrane Defects and Apoptosis Independent of Dystrophin

  1998cited by this paper
• A first missense mutation in the delta sarcoglycan gene associated with a severe phenotype and frequency of limb-girdle muscular dystrophy type 2F (LGMD2F) in Brazilian sarcoglycanopathies.

  1998cited by this paper
• Progressive Muscular Dystrophy in α-Sarcoglycan–deficient Mice

  1998influential reference
• The sarcoglycan complex in limb-girdle muscular dystrophy.

  1998influential reference
• Actin mutations in dilated cardiomyopathy, a heritable form of heart failure.

  1998cited by this paper
• Muscular dystrophies and the dystrophin-glycoprotein complex.

  1997cited by this paper
• A treadmill exercise regimen for identifying cardiovascular phenotypes in transgenic mice.

  1997cited by this paper
• Sarcospan, the 25-kDa Transmembrane Component of the Dystrophin-Glycoprotein Complex*

  1997cited by this paper
• MLP-deficient mice exhibit a disruption of cardiac cytoarchitectural organization, dilated cardiomyopathy, and heart failure.

  1997cited by this paper
• Disruption of muscle architecture and myocardial degeneration in mice lacking desmin

  1996cited by this paper
• Autosomal recessive limbgirdle muscular dystrophy, LGMD2F, is caused by a mutation in the δ–sarcoglycan gene

  1996cited by this paper
• Autosomal recessive limb-girdle muscular dystrophy, LGMD2F, is caused by a mutation in the delta-sarcoglycan gene.

  1996cited by this paper
• Mutations in the Dystrophin-Associated Protein γ-Sarcoglycan in Chromosome 13 Muscular Dystrophy

  1995cited by this paper
• Management of vasospastic angina—Role of nicorandil

  1995cited by this paper
• Mutations in the dystrophin-associated protein gamma-sarcoglycan in chromosome 13 muscular dystrophy.

  1995cited by this paper
• Missense mutations in the adhalin gene linked to autosomal recessive muscular dystrophy.

  1994cited by this paper
• Dystrophin protects the sarcolemma from stresses developed during muscle contraction.

  1993cited by this paper
• A role for the dystrophin-glycoprotein complex as a transmembrane linker between laminin and actin

  1993cited by this paper
• Molecular Mechanism of Action of Nicorandil

  1992cited by this paper
• Microvascular Spasm in the Cardiomyopathic Syrian Hamster: A Preventable Cause of Focal Myocardial Necrosis

  1982cited by this paper

• DISTROFIA MUSCULAR DE DUCHENNE

  2025cites this paper
• Dysregulated ATX-LPA and YAP/TAZ signaling in dystrophic Sgcd−/− mice with early fibrosis and inflammation

  2025cites this paper
• Integrated single‐cell functional‐proteomic profiling reveals a shift in myofibre specificity in human nemaline myopathy: A proof‐of‐principle study

  2025cites this paper
• Reduced cardiac antioxidant defenses mediate increased susceptibility to workload-induced myocardial injury in males with genetic cardiomyopathy.

  2024cites this paper
• Reduced microvascular flow-mediated dilation in Syrian hamsters lacking d-sarcoglycan is caused by increased oxidative stress.

  2024cites this paper
• Identification of key genes for cuproptosis in carotid atherosclerosis

  2024cites this paper
• Aging reveals a sex-dependent susceptibility of sarcospan-deficient mice to cardiometabolic disease

  2024cites this paper
• Histopathological analysis of gamma sarcoglycanopathy in Moroccan patients: A case series

  2024cites this paper
• The Abl1 tyrosine kinase is a key player in doxorubicin-induced cardiomyopathy and its p53/p73 cell death mediated signaling differs in atrial and ventricular cardiomyocytes

  2024cites this paper
• Differential Effectiveness of Poloxamer 188 in Dystrophic Cardiomyopathy Reveals Complex Pathophysiology

  2024cites this paper
• Protein glycosylation in cardiovascular health and disease

  2024cites this paper
• The Development of Robust Antibodies to Sarcospan, a Dystrophin- and Integrin-Associated Protein, for Basic and Translational Research

  2024cites this paper
• Challenges and Considerations of Preclinical Development for iPSC-Based Myogenic Cell Therapy

  2024cites this paper
• Mechanisms of reduced myocardial energetics of the dystrophic heart.

  2023cites this paper
• Successful treatment of acute myocardial injury of Duchenne muscular dystrophy with steroids: a case report

  2023cites this paper
• Modeling Sarcoglycanopathy in Danio rerio

  2023cites this paper
• Differential histological features and myogenic protein levels in distinct muscles of d-sarcoglycan null muscular dystrophy mouse model

  2023cites this paper
• Candidate Regulatory Genes for Hindlimb Development in the Embryos of the Chinese Alligator (Alligator sinensis)

  2023cites this paper
• Identification of Genetic Variants Associated with Severe Myocardial Bridging through Whole-Exome Sequencing

  2023cites this paper
• Re-examination of therapeutic management of muscular dystrophies using a vascular smooth muscle-centered approach

  2023cites this paper
• The importance of dystrophin and the dystrophin associated proteins in vascular smooth muscle

  2022cites this paper
• RETINAL VASCULAR DISEASE IN LIMB-GIRDLE MUSCULAR DYSTROPHY

  2022cites this paper
• Clinical and genetic spectrum of a large cohort of patients with δ-sarcoglycan muscular dystrophy

  2021cites this paper
• CRISPR/Cas Correction of Muscular Dystrophies.

  2021cites this paper
• Generation and network analysis of an RNA-seq transcriptional atlas for the rat

  2021cites this paper
• Dilated cardiomyopathy: a new insight into the rare but common cause of heart failure

  2021cites this paper
• LGMD. Identification, description and classification

  2020cites this paper
• Essential roles of the dystrophin-glycoprotein complex in different cardiac pathologies.

  2020cites this paper
• Mouse models for muscular dystrophies: an overview

  2020influential citation
• Analysis of Cardiac Metabolic Remodeling in Heart Failure Using Nuclear Medicine and Its Application: Japanese Society of Nuclear Cardiology Award.

  2020cites this paper
• Retrospective Study of Intercalated Disk Defects Associated with Dilated Cardiomyopathy, Atrial Thrombosis, and Heart Failure in BALB/c Mice Deficient in IL4 Receptor α.

  2020cites this paper
• Pigs with δ-sarcoglycan deficiency exhibit traits of genetic cardiomyopathy

  2020cites this paper
• Animal Models for Muscle Disease and Muscle Gene Therapy

  2019cites this paper
• Antagonism of the Thromboxane‐Prostanoid Receptor as a Potential Therapy for Cardiomyopathy of Muscular Dystrophy

  2019cites this paper
• Cross-sectional study into age-related pathology of mouse models for limb girdle muscular dystrophy types 2D and 2F

  2019cites this paper
• Various effects of AAV9-mediated βARKct gene therapy on the heart in dystrophin-deficient (mdx) mice and δ-sarcoglycan-deficient (Sgcd-/-) mice.

  2019cites this paper
• Amelioration of muscular dystrophy phenotype in mdx mice by inhibition of Flt1

  2019cites this paper
• Duchenne muscular dystrophy

  2019cites this paper
• SGCD Homozygous Nonsense Mutation (p.Arg97∗) Causing Limb-Girdle Muscular Dystrophy Type 2F (LGMD2F) in a Consanguineous Family, a Case Report

  2019cites this paper
• Metformin Enhances Autophagy and Provides Cardioprotection in &dgr;-Sarcoglycan Deficiency-Induced Dilated Cardiomyopathy

  2019cites this paper
• Preclinical Models of Dystrophic Cardiomyopathy and Therapies for the Dystrophic Heart

  2019cites this paper
• Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy

  2019cites this paper
• ABC of multifaceted dystrophin glycoprotein complex (DGC)

  2018cites this paper
• Myoediting: Toward Prevention of Muscular Dystrophy by Therapeutic Genome Editing.

  2018cites this paper
• (-)-Epicatechin inhibits development of dilated cardiomyopathy in δ sarcoglycan null mouse.

  2018cites this paper
• Morphological and functional analyses of skeletal muscles from an immunodeficient animal model of limb‐girdle muscular dystrophy type 2E

  2018cites this paper
• Humanizing the mdx mouse model of DMD: the long and the short of it

  2018cites this paper
• Biochemical and Functional Interplay Between Ion Channels and the Components of the Dystrophin-Associated Glycoprotein Complex

  2018cites this paper
• Nanospan, an alternatively spliced isoform of sarcospan, localizes to the sarcoplasmic reticulum in skeletal muscle and is absent in limb girdle muscular dystrophy 2F

  2017cites this paper
• Emerging therapeutic strategies for sarcoglycanopathy

  2017cites this paper
• 154 – Pathophysiology of Cardiomyopathies

  2017cites this paper
• Nanospan, an alternatively spliced isoform of sarcospan, localizes to the sarcoplasmic reticulum in skeletal muscle and is absent in limb girdle muscular dystrophy 2F

  2017cites this paper
• Challenging the mystique Connection. Deciphering cell-matrix interactions role in atherosclerosis and restenosis.

  2017cites this paper
• Explorer Genome-wide association study of anthropometric traits in Korcula Island , Croatia

  2017cites this paper
• Familial dilated cardiomyopathy: A multidisciplinary entity, from basic screening to novel circulating biomarkers.

  2017cites this paper
• Natural disease history of mouse models for limb girdle muscular dystrophy types 2D and 2F

  2017influential citation
• ECM-Related Myopathies and Muscular Dystrophies: Pros and Cons of Protein Therapies.

  2017cites this paper
• Basics of Skeletal Muscle Function and Normal Physiology

  2017cites this paper
• Modulation of Vascular ACE by Oxidative Stress in Young Syrian Cardiomyopathic Hamsters: Therapeutic Implications

  2016cites this paper
• Myocardial Contractile Dysfunction Is Present without Histopathology in a Mouse Model of Limb-Girdle Muscular Dystrophy-2F and Is Prevented after Claudin-5 Virotherapy

  2016cites this paper
• Pathogenesis, clinical features and diagnosis of sarcoglycanopathies

  2016cites this paper
• Morphological and Molecular Characterization of Human Dermal Lymphatic Collectors

  2016cites this paper
• El subcomplejo sarcoglicano-sarcospan: su importancia en el músculo estriado y tejido vascular

  2016cites this paper
• Where do we stand in trial readiness for autosomal recessive limb girdle muscular dystrophies?

  2016cites this paper
• Collagen VI deficiency reduces muscle pathology, but does not improve muscle function, in the γ-sarcoglycan-null mouse

  2016cites this paper
• A Review of Mathematical Models for Muscular Dystrophy: A Systems Biology Approach

  2016cites this paper
• The sarcoglycan complex in skeletal muscle.

  2016influential citation
• Molecular Signatures of Membrane Protein Complexes Underlying Muscular Dystrophy*

  2016cites this paper
• Limb-girdle Muscular Dystrophies

  2015cites this paper
• Angiotensin‐dependent autonomic dysregulation precedes dilated cardiomyopathy in a mouse model of muscular dystrophy

  2015cites this paper
• Assessment of ventricular function in mouse models of muscular dystrophy: a comparison of MRI with conductance catheter.

  2015cites this paper
• Pathology of the Developing Mouse from Conception to Weaning

  2015cites this paper
• Characterization of the dystrophin-glycoprotein complex in airway smooth muscle: role of δ-sarcoglycan in airway responsiveness.

  2015cites this paper
• Reduction of no-reflow and reperfusion injury with the synthetic 17β-aminoestrogen compound Prolame is associated with PI3K/Akt/eNOS signaling cascade

  2015cites this paper
• Na(+)-H(+) exchanger inhibitor prevents early death in hereditary cardiomyopathy.

  2015cites this paper
• muscle: insights from animal models Functional characteristics of dystrophic skeletal

  2015cites this paper
• Sarcospan Regulates Cardiac Isoproterenol Response and Prevents Duchenne Muscular Dystrophy–Associated Cardiomyopathy

  2015cites this paper
• muscular dystrophy The role of free radicals in the pathophysiology of

  2015cites this paper
• Expression pattern of mRNA A and mRNA B of alpha sarcoglycan gene during mouse embryonic development and regulation of their expression by myogenic and cardiogenic transcription factors

  2014cites this paper
• Chronic oral administration of Ang-(1-7) improves skeletal muscle, autonomic and locomotor phenotypes in muscular dystrophy.

  2014cites this paper
• (–)‐Epicatechin improves mitochondrial‐related protein levels and ameliorates oxidative stress in dystrophic δ‐sarcoglycan null mouse striated muscle

  2014cites this paper
• What do mouse models of muscular dystrophy tell us about the DAPC and its components?

  2014influential citation
• Finding the Sweet Spot: Assembly and Glycosylation of the Dystrophin‐Associated Glycoprotein Complex

  2014cites this paper
• Uncovering the complexity of muscular dystrophy pathology through disease signaling

  2014cites this paper
• Fibromodulin and Dystrophin in Atherosclerosis: Novel roles for extracellular matrix in plaque development

  2014cites this paper
• Muscle fatigue, nNOS and muscle fiber atrophy in limb girdle muscular dystrophy

  2014cites this paper
• Mouse models of heart failure: cell signaling and cell survival.

  2014influential citation
• Description of a utrophin associated protein complex in lipid raft domains of human artery smooth muscle cells.

  2014cites this paper
• Loss of dystrophin and β-sarcoglycan significantly exacerbates the phenotype of laminin α2 chain-deficient animals.

  2014cites this paper
• S151A δ-sarcoglycan mutation causes a mild phenotype of cardiomyopathy in mice

  2013cites this paper
• Rodent models of heart failure: an updated review

  2013cites this paper
• Sarcospan: a small protein with large potential for Duchenne muscular dystrophy

  2013cites this paper
• Genetic variation at the delta‐sarcoglycan (SGCD) locus elevates heritable sympathetic nerve activity in human twin pairs

  2013cites this paper
• Beta-Blockers, Left and Right Ventricular Function, and In-Vivo Calcium Influx in Muscular Dystrophy Cardiomyopathy

  2013cites this paper
• Mendelian Forms of Structural Cardiovascular Disease

  2013cites this paper
• Heterogeneous abnormalities of in-vivo left ventricular calcium influx and function in mouse models of muscular dystrophy cardiomyopathy

  2013cites this paper
• Rodent models of heart failure: an updated review

  2013cites this paper
• ECM-related gene expression profile in vascular smooth muscle cells from human saphenous vein and internal thoracic artery

  2013cites this paper
• Works Title Sarcospan : a small protein with large potential for Duchenne muscular dystrophy

  2013cites this paper
• Degenerative Neurological and Neuromuscular Disease Recent advances in Duchenne muscular dystrophy

  2012cites this paper