Cyclin-dependent kinase 5 activity is required for T cell activation and induction of experimental autoimmune encephalomyelitis

T. Pareek,E. Lam,Xiaojing Zheng,D. Askew,A. Kulkarni,M. Chance,A. Huang,K. Cooke,J. Letterio

Published 2010 in Journal of Experimental Medicine

ABSTRACT

Cyclin-dependent kinase 5 drives T cell activation and disease in EAE in part by regulating the actin binding protein coronin 1a.

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