Gene transfer with echo-enhanced contrast agents: comparison between Albunex, Optison, and Levovist in mice--initial results.

No abstract is available for this paper.

• Publication year

  2003

• Venue

  Radiology

• Publication date

  2003-11-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1148/RADIOL.2292020500PMID 14512507
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Local Delivery of Plasmid DNA Into Rat Carotid Artery Using Ultrasound

  2002cited by this paper
• Effects of dissolved gases and an echo contrast agent on apoptosis induced by ultrasound and its mechanism via the mitochondria-caspase pathway.

  2002cited by this paper
• Gene Delivery Using Ultrasound Contrast Agents

  2001cited by this paper
• The Use of Ultrasound for Drug Delivery

  2001cited by this paper
• A comparison of the hemolytic potential of Optison and Albunex in whole human blood in vitro: acoustic pressure, ultrasound frequency, donor and passive cavitation detection considerations.

  2001cited by this paper
• High-efficiency endovascular gene delivery via therapeutic ultrasound.

  2001cited by this paper
• Delivery of Drugs with Ultrasound

  2001cited by this paper
• Ultrasound Gene Therapy: On the Road from Concept to Reality

  2001cited by this paper
• Inhibition of carotid artery neointimal formation with intravenous microbubbles.

  2001cited by this paper
• Therapeutic Ultrasound for Gene Delivery

  2001cited by this paper
• Ultrasound-mediated disruption of cell membranes. I. Quantification of molecular uptake and cell viability.

  2001cited by this paper
• Experimental study of the effects of Optison concentration on sonoporation in vitro.

  2000cited by this paper
• Left Ventricular Electromechanical Mapping to Assess Efficacy of phVEGF165 Gene Transfer for Therapeutic Angiogenesis in Chronic Myocardial Ischemia

  2000cited by this paper
• Ultrasound Facilitates Transduction of Naked Plasmid DNA into Colon Carcinoma Cells in Vitro and in Vivo

  2000cited by this paper
• Ultrasound enhancement of liposome-mediated cell transfection is caused by cavitation effects.

  2000cited by this paper
• Echocardiographic destruction of albumin microbubbles directs gene delivery to the myocardium.

  2000cited by this paper
• Lower-Extremity Edema Associated with Gene Transfer of Naked DNA Encoding Vascular Endothelial Growth Factor

  2000cited by this paper
• Microbubble-enhanced ultrasound for vascular gene delivery

  2000cited by this paper
• Development of Echogenic, Plasmid-Incorporated, Tissue-Targeted Cationic Liposomes that Can Be Used for Directed Gene Delivery

  2000cited by this paper
• Induction of cell-membrane porosity by ultrasound.

  1999cited by this paper
• Ultrasonic enhancement of gene transfection in murine melanoma tumors.

  1999cited by this paper
• A comparison of shock wave and sinusoidal-focused ultrasound-induced localized transfection of HeLa cells.

  1999cited by this paper
• Six-month assessment of a phase I trial of angiogenic gene therapy for the treatment of coronary artery disease using direct intramyocardial administration of an adenovirus vector expressing the VEGF121 cDNA.

  1999cited by this paper
• In vivo transfection of melanoma cells by lithotripter shock waves.

  1998cited by this paper
• Artificial cavitation nuclei significantly enhance acoustically induced cell transfection.

  1998cited by this paper
• Delivery of colloidal particles and red blood cells to tissue through microvessel ruptures created by targeted microbubble destruction with ultrasound.

  1998cited by this paper
• Ultrasound enhances gene expression of liposomal transfection.

  1997cited by this paper
• Transfection of a reporter plasmid into cultured cells by sonoporation in vitro.

  1997cited by this paper
• Clinical evidence of angiogenesis after arterial gene transfer of phVEGF165 in patient with ischaemic limb.

  1996cited by this paper
• Ultrasound-Mediated Transfection of Mammalian Cells

  1996cited by this paper
• Albumin microbubble echo-contrast material as an enhancer for ultrasound accelerated thrombolysis.

  1995cited by this paper

• Progress on liposome delivery systems in the treatment of bladder cancer

  2025cites this paper
• Exon Skipping by Ultrasound-Enhanced Delivery of Morpholino with Bubble Liposomes for Myotonic Dystrophy Model Mice.

  2025cites this paper
• Unveiling Multifaceted Avenues of Echogenic Liposomes: Properties, Preparation, and Potential Applications

  2024cites this paper
• From concept to early clinical trials: 30 years of microbubble-based ultrasound-mediated drug delivery research.

  2024cites this paper
• Fluorinated MOF-Based Hexafluoropropylene Nanotrap for Highly Efficient Purification of Octafluoropropane Electronic Specialty Gas.

  2024cites this paper
• Development of a Gene and Nucleic Acid Delivery System for Skeletal Muscle Administration via Limb Perfusion Using Nanobubbles and Ultrasound

  2023cites this paper
• Exosomes as an Emerging Plasmid Delivery Vehicle for Gene Therapy

  2023cites this paper
• Microbubbles Stabilized by Protein Shell: From Pioneering Ultrasound Contrast Agents to Advanced Theranostic Systems

  2022cites this paper
• Ultrasound-Mediated Drug Delivery: Sonoporation Mechanisms, Biophysics, and Critical Factors

  2022cites this paper
• An acoustic field-based conformal transfection system for improving the gene delivery efficiency.

  2021cites this paper
• Nanobubble Mediated Gene Delivery in Conjunction With a Hand-Held Ultrasound Scanner

  2020cites this paper
• Mechanisms underlying sonoporation: Interaction between microbubbles and cells.

  2020cites this paper
• Potential Therapeutic Usage of Nanomedicine for Glaucoma Treatment

  2020cites this paper
• Measurement of biological effects by bubble cavitation using back-propagation of acoustic emission

  2019cites this paper
• Advances on non‐invasive physically triggered nucleic acid delivery from nanocarriers

  2019cites this paper
• Observing Bubble Cavitation by Back-Propagation of Acoustic Emission Signals

  2019cites this paper
• Nonviral ultrasound-mediated gene delivery in small and large animal models

  2019cites this paper
• Real-time visualization of instantaneous frequency from bubble cavitation using color Doppler ultrasound imaging

  2019cites this paper
• Enhancing Nab-paclitaxel delivery using microbubble-assisted ultrasound in a pancreatic cancer model.

  2019cites this paper
• Exon Skipping by Ultrasound-Enhanced Delivery of Morpholino with Bubble Liposomes for Myotonic Dystrophy Model Mice.

  2018cites this paper
• PMO Delivery System Using Bubble Liposomes and Ultrasound Exposure for Duchenne Muscular Dystrophy Treatment.

  2018cites this paper
• BUBBLE LIPOSOME: A MODERN THERANOSTIC APPROACH OF NEW DRUG DELIVERY

  2017cites this paper
• Time-resolved measurement of bubble cavitation by using power Doppler ultrasound image

  2017cites this paper
• Inverse effects of flowing phase-shift nanodroplets and lipid-shelled microbubbles on subsequent cavitation during focused ultrasound exposures.

  2017cites this paper
• Microbubbles used for contrast enhanced ultrasound and theragnosis: a review of principles to applications

  2017cites this paper
• In situ bone tissue engineering via ultrasound-mediated gene delivery to endogenous progenitor cells in mini-pigs

  2017cites this paper
• Time-resolved measurement of bubble cavitation by combination of ultrasound power Doppler image and delayed US irradiation

  2016cites this paper
• Induction of Apoptosis in U937 Cells by Using a Combination of Bortezomib and Low-Intensity Ultrasound

  2016cites this paper
• Noninvasive optical diagnostics of enhanced green fluorescent protein expression in skeletal muscle for comparison of electroporation and sonoporation efficiencies

  2016cites this paper
• Multiparameter evaluation of in vivo gene delivery using ultrasound-guided, microbubble-enhanced sonoporation.

  2016cites this paper
• DNA uptake, intracellular trafficking and gene transfection after ultrasound exposure.

  2016cites this paper
• Gene delivery systems by the combination of lipid bubbles and ultrasound.

  2016cites this paper
• Enhancing effect of ultrasound on boron concentrations in an oral squamous cell carcinoma cell line SAS for boron neutron capture therapy

  2015cites this paper
• Analysis of Metrics for Molecular Sonotransfer in Vitro.

  2015cites this paper
• Nonviral gene delivery systems by the combination of bubble liposomes and ultrasound.

  2015cites this paper
• Enhancement of Blood–Brain Barrier Permeability and Delivery of Antisense Oligonucleotides or Plasmid DNA to the Brain by the Combination of Bubble Liposomes and High-Intensity Focused Ultrasound

  2015cites this paper
• Bio-effects of non-ionizing electromagnetic fields in context of cancer therapy.

  2014cites this paper
• Gene delivery to periodontal tissue using Bubble liposomes and ultrasound.

  2014cites this paper
• Evaluation of the specific adsorption of biotinylated microbubbles using a quartz crystal microbalance.

  2014cites this paper
• Specific contrast ultrasound using sterically stabilized microbubbles for early diagnosis of thromboembolic disease in a rabbit model.

  2014cites this paper
• Nucleic acid delivery with microbubbles and ultrasound.

  2014cites this paper
• High intensity focused ultrasound technology, its scope and applications in therapy and drug delivery.

  2014cites this paper
• Gene therapy for peripheral arterial disease

  2014cites this paper
• Improvement in microhollow production using bubble cloud cavitation by dual-frequency ultrasonic wave irradiation

  2014cites this paper
• Activation of microbubbles by low-level therapeutic ultrasound enhances the antitumor effects of doxorubicin

  2014cites this paper
• Destruction of polylactic acid microcapsules under ultrasound irradiation

  2014cites this paper
• Bubble liposomes and ultrasound exposure improve localized morpholino oligomer delivery into the skeletal muscles of dystrophic mdx mice.

  2014cites this paper
• Ultrasound-mediated delivery systems using nano/microbubbles or bubble liposomes

  2013cites this paper
• Microbubble attenuation and destruction: are they involved in sonoporation efficiency?

  2013cites this paper
• Micro- and nanobubbles: a versatile non-viral platform for gene delivery.

  2013cites this paper
• Micro-scale fluid flows: the application of acoustic streaming to biomedical research

  2013cites this paper
• Ultrasound-mediated gene delivery systems by AG73-modified Bubble liposomes.

  2013cites this paper
• Hypolipidemic effect of SR‑BI gene delivery by combining cationic liposomal microbubbles and ultrasound in hypercholesterolemic rats.

  2013cites this paper
• Basic research on a new therapy system combining ultrasound and drug delivery

  2013cites this paper
• pDNA-loaded Bubble liposomes as potential ultrasound imaging and gene delivery agents.

  2013cites this paper
• New development and application of ultrasound targeted microbubble destruction in gene therapy and drug delivery.

  2013cites this paper
• Etude de la perméabilisation de la membrane plasmique et des membranes des organites cellulaires par des agents chimiques et physiques

  2013cites this paper
• Efficacy of HGF carried by ultrasound microbubble-cationic nano-liposomes complex for treating hepatic fibrosis in a bile duct ligation rat model, and its relationship with the diffusion-weighted MRI parameters.

  2013cites this paper
• Transendocardial delivery of HGF via microbubbles and ultrasound to treat acute myocardial infarction.

  2013cites this paper
• A transendocardial delivery and intracardiac ultrasound irradiation treatment catheter

  2013cites this paper
• Influence of cell line and cell cycle phase on sonoporation transfection efficiency in cervical carcinoma cells under the same physical conditions

  2013cites this paper
• Simultaneous Observation of Bubble Clouds and Microhollows Produced by Bubble Cloud Cavitation

  2013cites this paper
• A targeted high-efficiency angiogenesis strategy as therapy for myocardial infarction.

  2012cites this paper
• Ultrasound and microbubble-assisted gene delivery: recent advances and ongoing challenges.

  2012cites this paper
• Enhancing effect of ultrasound-mediated microbubble destruction on gene delivery into rat kidney via different administration routes.

  2012cites this paper
• Optimization of transfection parameters for ultrasound/SonoVue microbubble-mediated hAng-1 gene delivery in vitro.

  2012cites this paper
• Microbubbles as a vehicle for gene and drug delivery: current clinical implications and future perspectives.

  2012cites this paper
• Neuroepithelial Transforming Protein 1 Short Interfering RNA–Mediated Gene Silencing With Microbubble and Ultrasound Exposure Inhibits the Proliferation of Hepatic Carcinoma Cells In Vitro

  2012cites this paper
• Studies on neutral, cationic and biotinylated cationic microbubbles in enhancing ultrasound-mediated gene delivery in vitro and in vivo.

  2012cites this paper
• Theoretical and experimental characterisation of magnetic microbubbles.

  2012cites this paper
• Can ultrasound enable efficient intracellular uptake of molecules? A retrospective literature review and analysis.

  2012cites this paper
• Gene delivery system involving Bubble liposomes and ultrasound for the efficient in vivo delivery of genes into mouse tongue tissue.

  2012cites this paper
• Functionalized carriers for the improved delivery of plasminogen activators.

  2012cites this paper
• Hepatocyte growth factor-loaded ultrasound contrast agent for restoration of injured facial nerves in Sprague Dawley (SD) rats

  2012cites this paper
• Development of nucleic acid drugs for neurological disorders.

  2012cites this paper
• Enhancement of chitosan nanoparticle-facilitated gene transfection by ultrasound both in vitro and in vivo.

  2012cites this paper
• Contribution THEORETICAL AND EXPERIMENTAL CHARACTERISATION OF MAGNETIC MICROBUBBLES

  2012cites this paper
• Microbubble Sonodestruction Rate as a Metric to Evaluate Sonoporation Efficiency

  2012cites this paper
• Magnetic targeting and ultrasound mediated drug delivery: Benefits, limitations and combination

  2012cites this paper
• Augmentation of transgenic expression by ultrasound-mediated liposome microbubble destruction

  2012cites this paper
• The effect of glucosamine on the acoustic and binding properties of albumin-based microbubbles (work in progress)

  2012cites this paper
• Albumin coated microbubble optimization: custom fabrication and comprehensive characterization.

  2012cites this paper
• Feasibility and effect of ultrasound microbubble-mediated wild-type p53 gene transfection of HeLa cells.

  2012cites this paper
• A new method of ultrasonic nonviral gene delivery to the adult myocardium.

  2012cites this paper
• Efficient microbubble- and ultrasound-mediated plasmid DNA delivery into a specific rat liver lobe via a targeted injection and acoustic exposure using a novel ultrasound system.

  2012cites this paper
• An investigation into factors affecting ultrasound and microbubble mediated gene transfection

  2012influential citation
• Efficient siRNA delivery using novel siRNA-loaded Bubble liposomes and ultrasound.

  2012cites this paper
• Using acoustic cavitation to enhance chemotherapy of DOX liposomes: experiment in vitro and in vivo

  2012cites this paper
• Effect of albumin and dextrose concentration on ultrasound and microbubble mediated gene transfection in vivo.

  2012cites this paper
• RETRACTED ARTICLE: A novel method of augmenting gene expression and angiogenesis in the normal and ischemic canine myocardium

  2012cites this paper
• Systemic delivery systems of angiogenic gene by novel bubble liposomes containing cationic lipid and ultrasound exposure.

  2012cites this paper
• Retraction Note: A novel method of augmenting gene expression and angiogenesis in the normal and ischemic canine myocardium

  2012cites this paper
• siRNA delivery system using Bubble liposomes and ultrasound

  2012cites this paper
• Compare ultrasound-mediated heating and cavitation between flowing polymer- and lipid-shelled microbubbles during focused ultrasound exposures.

  2012cites this paper
• Sonoporation-mediated anti-angiogenic gene transfer into muscle effectively regresses distant orthotopic tumors

  2011cites this paper
• In vivo gene transfer into the ocular ciliary muscle mediated by ultrasound and microbubbles.

  2011cites this paper
• Viscous effects on the oscillations of two equal and deformable bubbles under a step change in pressure

  2011cites this paper
• Plasmid DNA-based gene transfer with ultrasound and microbubbles.

  2011cites this paper
• The improvement of liposome-mediated transfection of pEGFP DNA into human prostate cancer cells by combining low-frequency and low-energy ultrasound with microbubbles.

  2011cites this paper
• P85, Optison microbubbles and ultrasound cooperate in mediating plasmid DNA transfection in mouse skeletal muscles in vivo.

  2011cites this paper