Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinoma

No abstract is available for this paper.

• Publication year

  1999

• Venue

  Oncogene

• Publication date

  1999-11-25

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/sj.onc.1203192PMID 10597307
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Occasional loss of constitutive heterozygosity at 11p15.5 and imprinting relaxation of theIGFII maternal allele in hepatoblastoma

  2005cited by this paper
• Two novel genes in the center of the 11p15 imprinted domain escape genomic imprinting.

  1999cited by this paper
• Genomic imprinting of H19 and insulin‐like growth factor‐2 in pediatric germ cell tumors

  1999cited by this paper
• High frequency of inactivation of the imprinted H19 gene in “sporadic” hepatoblastoma

  1999cited by this paper
• Multipoint analysis of human chromosome 11p15/mouse distal chromosome 7: inclusion of H19/IGF2 in the minimal WT2 region, gene specificity of H19 silencing in Wilms' tumorigenesis and methylation hyper-dependence of H19 imprinting.

  1999cited by this paper
• Genomic imprinting is disrupted in interspecific Peromyscus hybrids

  1998cited by this paper
• Loss of imprinting in disease progression in chronic myelogenous leukemia.

  1998cited by this paper
• Frequent loss of imprinting of the H19 and IGF-II genes in ovarian tumors.

  1998cited by this paper
• Loss of imprinting of igf2 in renal‐cell carcinomas

  1998influential reference
• Loss of imprinting in normal tissue of colorectal cancer patients with microsatellite instability

  1998cited by this paper
• Loss of Imprinting in Disease Progression in Chronic Myelogenous Leukemia

  1998cited by this paper
• Loss of imprinting of IGF2 and not H19 in breast cancer, adjacent normal tissue and derived fibroblast cultures

  1998influential reference
• Presence of multiple incontiguous deleted regions at the long arm of chromosome 18 in head and neck cancer.

  1998cited by this paper
• The mouse H19 locus mediates a transition between imprinted and non-imprinted DNA replication patterns.

  1998cited by this paper
• Competition—a common motif for the imprinting mechanism?

  1997cited by this paper
• Unique expression patterns of H19 in human testicular cancers of different etiology

  1997cited by this paper
• Disrupted IGF2 promoter control by silencing of promoter P1 in human hepatocellular carcinoma.

  1997cited by this paper
• Loss of imprinting of the insulin-like growth factor II gene in renal cell carcinoma.

  1997influential reference
• Paternal expression of WT1 in human fibroblasts and lymphocytes.

  1997cited by this paper
• Loss of imprinting and overexpression of IGF2 gene in gastric adenocarcinoma.

  1997cited by this paper
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  1997cited by this paper
• DNA METHYLATION: Tying It All Together: Epigenetics, Genetics, Cell Cycle, and Cancer

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  1997cited by this paper
• Deletion mapping of chromosome 4 in head and neck squamous cell carcinoma

  1997cited by this paper
• The insulin-like growth factor II receptor gene is mutated in genetically unstable cancers of the endometrium, stomach, and colorectum.

  1997cited by this paper
• Inactivation of H19, an imprinted and putative tumor repressor gene, is a preneoplastic event during Wilms' tumorigenesis.

  1997influential reference
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  1996cited by this paper
• Allelic loss and replication errors at microsatellite loci on chromosome 11p in head and neck squamous carcinoma: association with aggressive biological features.

  1996cited by this paper
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  1996cited by this paper
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  1996cited by this paper
• Reduced expression of the cyclin-dependent kinase inhibitor gene p57KIP2 in Wilms' tumor.

  1996cited by this paper
• High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma.

  1996cited by this paper
• IGF2 but not H19 shows loss of imprinting in human glioma.

  1996cited by this paper
• Loss of H19 imprinting in esophageal cancer.

  1996cited by this paper
• Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.

  1995cited by this paper
• Imprinting mutations in the Beckwith-Wiedemann syndrome suggested by altered imprinting pattern in the IGF2-H19 domain.

  1995cited by this paper
• Frequent loss of imprinting of the H19 gene is often associated with its overexpression in human lung cancers.

  1995cited by this paper
• Maintenance of normal imprinting of H19 and IGF2 genes in neuroblastoma.

  1995cited by this paper
• Sequential p53 mutation analysis of pre‐invasive and invasive head and neck squamous carcinoma

  1995cited by this paper
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  1995cited by this paper
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  1995cited by this paper
• Sequential loss of heterozygosity at microsatellite motifs in preinvasive and invasive head and neck squamous carcinoma.

  1995cited by this paper
• Deregulation of both imprinted and expressed alleles of the insulin–like growth factor 2 gene during β–cell tumorigenesis

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  1994cited by this paper
• Parental Imprinting of Human Chromosome Region 11p15.3-pter Involved in the Beckwith-Wiedemann Syndrome and Various Human Neoplasia

  1994cited by this paper
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  1994cited by this paper
• Mosaic and polymorphic imprinting of the WT1 gene in humans

  1994cited by this paper
• An allelotype of squamous carcinoma of the head and neck using microsatellite markers.

  1994cited by this paper
• Erratum: Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

  1994influential reference
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  1994influential reference
• Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour

  1994influential reference
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  1993cited by this paper
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  1993influential reference
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  1990cited by this paper
• Loss of allelic heterozygosity at a second locus on chromosome 11 in sporadic Wilms' tumor cells

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• Estimates of the worldwide frequency of sixteen major cancers in 1980

  1988cited by this paper
• Parental legacy determines methylation and expression of an autosomal transgene: a molecular mechanism for parental imprinting.

  1987cited by this paper
• Genetic mechanisms of tumor-specific loss of 11p DNA sequences in Wilms tumor.

  1987cited by this paper

• The role of imprinting genes’ loss of imprints in cancers and their clinical implications

  2024cites this paper
• Epigenetic modulation of long noncoding RNA H19 in oral squamous cell carcinoma-A narrative review

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• LncRNAs as key players in the MYC pathways

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• Targeting lncRNA H19/miR-29b/COL1A1 Axis Impedes Myofibroblast Activities of Precancerous Oral Submucous Fibrosis

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• An updated review of the H19 lncRNA in human cancer: molecular mechanism and diagnostic and therapeutic importance

  2020cites this paper
• High level of lncRNA H19 expression is associated with shorter survival in esophageal squamous cell cancer patients.

  2019cites this paper
• LncRNA H19-elevated LIN28B promotes lung cancer progression through sequestering miR-196b

  2018cites this paper
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  2018cites this paper
• CpG location and methylation level are crucial factors for the early detection of oral squamous cell carcinoma in brushing samples using bisulfite sequencing of a 13-gene panel

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• Upregulated long non-coding RNA LINC00152 expression is associated with progression and poor prognosis of tongue squamous cell carcinoma

  2017cites this paper
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  2017cites this paper
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  2015cites this paper
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  2013cites this paper
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  2012cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
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  2010cites this paper
• Allele-Specific Expression Analysis of PEG1/MEST in Head and Neck Squamous Cell Carcinomas

  2009cites this paper
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  2009cites this paper
• Frequent aberrant methylation of the imprinted IGF2/H19 locus and LINE1 hypomethylation in ovarian carcinoma.

  2009cites this paper
• IGF-I protects human oral buccal mucosal epithelial cells from sodium nitroprusside-induced apoptosis via PI3-kinase.

  2008cites this paper
• Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma

  2008influential citation
• High-grade neuroendocrine carcinomas of the lung express K homology domain containing protein overexpressed in cancer but carcinoid tumors do not.

  2007cites this paper
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  2007cites this paper
• Loss of Imprinting of IGF2 as an Epigenetic Marker for the Risk of Human Cancer

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  2007cites this paper
• H19-DMR allele-specific methylation analysis reveals epigenetic heterogeneity of CTCF binding site 6 but not of site 5 in head-and-neck carcinomas: a pilot case-control analysis.

  2006cites this paper
• Frequent IGF2/H19 Domain Epigenetic Alterations and Elevated IGF2 Expression in Epithelial Ovarian Cancer

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• DNA methylation in the CTCF‐binding site I and the expression pattern of the H19 gene: Does positive expression predict poor prognosis in early stage head and neck carcinomas?

  2005cites this paper
• The Oncofetal H19 RNA in human cancer, from the bench to the patient

  2005cites this paper
• Down-regulation of the IGF-2/H19 locus during normal and malignant hematopoiesis is independent of the imprinting pattern.

  2005cites this paper
• Imprinting status of DLK1 gene in brain tumors and lymphomas.

  2004cites this paper
• Loss of imprinting of IGF2 and H19 in osteosarcoma is accompanied by reciprocal methylation changes of a CTCF-binding site.

  2003cites this paper
• CTCF binding at the insulin-like growth factor-II (IGF2)/H19 imprinting control region is insufficient to regulate IGF2/H19 expression in human tissues.

  2003cites this paper
• Oncogenes and Tumor Suppressor Genes in Oral or Head and Neck Squamous Cell Carcinoma

  2003cites this paper
• Loss of genomic imprinting of insulin-like growth factor 2 is strongly associated with cellular proliferation in normal hematopoietic cells.

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• Multipoint imprinting analysis indicates a common precursor cell for gonadal and nongonadal pediatric germ cell tumors.

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• Imprinting of the Gsα gene GNAS1 in the pathogenesis of acromegaly

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• Genetic aberrations in oral or head and neck squamous cell carcinoma 2: chromosomal aberrations.

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