The mouse H19 locus mediates a transition between imprinted and non-imprinted DNA replication patterns.

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Human Molecular Genetics

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/HMG/7.1.91PMID 9384608
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• An imprinting element from the mouse H19 locus functions as a silencer in Drosophila

  1997cited by this paper
• Expression of H19 does not influence the timing of replication of the Igf2/H19 imprinted region.

  1997cited by this paper
• Loss of the maternal H19 gene induces changes in Igf2 methylation in both cis and trans.

  1997cited by this paper
• Deletion of the H19 transcription unit reveals the existence of a putative imprinting control element.

  1997cited by this paper
• A 5' differentially methylated sequence and the 3'-flanking region are necessary for H19 transgene imprinting

  1997cited by this paper
• Fab-7 functions as a chromatin domain boundary to ensure proper segment specification by the Drosophila bithorax complex.

  1996cited by this paper
• The structural H19 gene is required for transgene imprinting.

  1996cited by this paper
• A novel human homologue of yeast nucleosome assembly protein, 65 kb centromeric to the p57KIP2 gene, is biallelically expressed in fetal and adult tissues.

  1996cited by this paper
• An extended region of biallelic gene expression and rodent-human synteny downstream of the imprinted H19 gene on chromosome 11p15.5.

  1996influential reference
• Factors affecting the timing and imprinting of replication on a mammalian chromosome.

  1995cited by this paper
• A novel L23-related gene 40 kb downstream of the imprinted H19 gene is biallelically expressed in mid-fetal and adult human tissues.

  1995influential reference
• Targeted deletion of 5'HS2 of the murine beta-globin LCR reveals that it is not essential for proper regulation of the beta-globin locus.

  1995cited by this paper
• Allele-specific replication timing in imprinted domains: absence of asynchrony at several loci.

  1995cited by this paper
• Imprinted chromosomal regions of the human genome display sex-specific meiotic recombination frequencies.

  1995cited by this paper
• A Drosophila protein that imparts directionality on a chromatin insulator is an enhancer of position-effect variegation.

  1995cited by this paper
• Disruption of imprinting caused by deletion of the H19 gene region in mice

  1995cited by this paper
• Sex-specific meiotic recombination in the Prader--Willi/Angelman syndrome imprinted region.

  1995cited by this paper
• An enhancer deletion affects both H19 and Igf2 expression.

  1995cited by this paper
• New insights reveal complex mechanisms involved in genomic imprinting.

  1994cited by this paper
• Allele specific inactivation of insulin 1 and 2, in the mouse yolk sac, indicates imprinting

  1994cited by this paper
• DNA methylation and genomic imprinting.

  1994cited by this paper
• Comparative analysis of Igf-2/H19 imprinted domain: identification of a highly conserved intergenic DNase I hypersensitive region.

  1994cited by this paper
• Hypersensitive site 5 of the human beta locus control region functions as a chromatin insulator.

  1994cited by this paper
• Allele-specific replication timing of imprinted gene regions

  1993influential reference
• A 5′ element of the chicken β-globin domain serves as an insulator in human erythroid cells and protects against position effect in Drosophila

  1993cited by this paper
• Silence of the genes

  1993cited by this paper
• The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position‐effects.

  1993cited by this paper
• Genomic imprinting. Silence of the genes.

  1993cited by this paper
• Replication structure of the human & beta;-globin gene domain

  1993cited by this paper
• A group of scs elements function as domain boundaries in an enhancer-blocking assay

  1992cited by this paper
• Simultaneous visualization of seven different DNA probes by in situ hybridization using combinatorial fluorescence and digital imaging microscopy.

  1992cited by this paper
• Physical linkage of two mammalian imprinted genes, H19 and insulin–like growth factor 2

  1992cited by this paper
• Analysis of genes and chromosomes by nonisotopic in situ hybridization.

  1991cited by this paper
• Parental imprinting of the mouse H19 gene

  1991cited by this paper
• Parental imprinting of the mouse insulin-like growth factor II gene.

  1991cited by this paper
• Genomic imprinting.

  1988cited by this paper
• Human Chromosomes

  1945cited by this paper

• Livestock species as emerging models for genomic imprinting

  2024cites this paper
• Parent-of-origin-specific DNA replication timing is confined to large imprinted regions.

  2024cites this paper
• Chromatin Topology and Transcription in Myogenesis

  2017cites this paper
• Dissecting the multiple roles of the Igf2r imprint control element

  2010influential citation
• Expressionsanalysen geprägter Gene in der Prader-Willi-/Angelman-Syndrom-Region

  2010cites this paper
• Algorithmic analysis of human dna replication timing from discrete microarray data

  2008cites this paper
• Extraction of Human DNA Replication Timing Patterns from Discrete Microarray Data

  2008cites this paper
• CTCF Regulates Asynchronous Replication of the Imprinted H19/Igf2 Domain

  2007cites this paper
• Epigenetic Regulation of Replication Timing and Signal Transduction

  2006cites this paper
• The Control of the Epigenome

  2006cites this paper
• Applying whole-genome studies of epigenetic regulation to study human disease

  2006cites this paper
• Epigenetic regulation of mammalian imprinted genes: from primary to functional imprints.

  2005cites this paper
• Chicken orthologues of mammalian imprinted genes are clustered on macrochromosomes and replicate asynchronously.

  2005cites this paper
• Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization.

  2003influential citation
• Paternal imprints can be established on the maternal Igf2-H19 locus without altering replication timing of DNA.

  2003cites this paper
• Identification of four highly conserved genes between breakpoint hotspots BP1 and BP2 of the Prader-Willi/Angelman syndromes deletion region that have undergone evolutionary transposition mediated by flanking duplicons.

  2003influential citation
• Genomic domains and regulatory elements operating at the domain level.

  2003cites this paper
• Epigenetic abnormalities associated with a chromosome 18(q21-q22) inversion and a Gilles de la Tourette syndrome phenotype

  2003cites this paper
• Initiation of DNA Replication in Cells of Higher Eukaryotes

  2003cites this paper
• An evolutionarily conserved putative insulator element near the 3' boundary of the imprinted Igf2/H19 domain.

  2002cites this paper
• Replication Timing Properties within the Mouse Distal Chromosome 7 Imprinting Cluster

  2002cites this paper
• DNA methylation in genomic imprinting, development, and disease

  2001cites this paper
• Flow cytometry and FISH to investigate allele-specific replication timing and homologous association of imprinted chromosomes.

  2001cites this paper
• Epigenetic reprogramming of the genome--from the germ line to the embryo and back again.

  2001cites this paper
• Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2‐H19 domain

  2001cites this paper
• Differential chromatin packaging of genomic imprinted regions between expressed and non-expressed alleles.

  2000cites this paper
• Deletion of a silencer element disrupts H19 imprinting independently of a DNA methylation epigenetic switch.

  2000influential citation
• Imprinting: focusing on the center.

  2000cites this paper
• Genetics of childhood disorders: XIII. Genomic imprinting: the indelible mark of the gamete.

  2000cites this paper
• An imprinted antisense transcript at the human GNAS1 locus.

  2000cites this paper
• Loss of imprinting and genetic alterations of the cyclin-dependent kinase inhibitor p57KIP2 gene in head and neck squamous cell carcinoma.

  2000cites this paper
• Alterations of H19 imprinting and IGF2 replication timing are infrequent in Beckwith-Wiedemann syndrome.

  2000cites this paper
• Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndrome.

  2000cites this paper
• Asynchronous replication of imprinted genes is established in the gametes and maintained during development

  1999cites this paper
• The mechanisms of genomic imprinting.

  1999cites this paper
• Genomic imprinting and cancer.

  1999cites this paper
• A kinetic proofreading mechanism for disentanglement of DNA by topoisomerases

  1999cites this paper
• Meiotic chromosomes: integrating structure and function.

  1999cites this paper
• Parental Allele-Specific Chromatin Configuration in a Boundary–Imprinting-Control Element Upstream of the MouseH19 Gene

  1999cites this paper
• Frequent loss of imprinting at the IGF2 and H19 genes in head and neck squamous carcinoma

  1999cites this paper
• Stopped at the border: boundaries and insulators.

  1999cites this paper
• Genomic imprinting and chromatin insulation in beckwith-wiedemann syndrome

  1999cites this paper
• Chromatin conformation of the H19 epigenetic mark.

  1998cites this paper
• Mechanism of imprinting on mouse distal chromosome 7.

  1998influential citation
• Fluorescence in situ hybridization analysis of the replication properties of the myotonic dystrophy protein kinase (DMPK) gene region

  1998cites this paper
• Sequence of a 42-kb mouse region containing the imprinted H19 locus: identification of a novel muscle-specific transcription unit showing biallelic expression

  1998influential citation
• Syntenic organization of the mouse distal chromosome 7 imprinting cluster and the Beckwith-Wiedemann syndrome region in chromosome 11p15.5.

  1998cites this paper
• Supplementary Results Table 1. High-and Lower-confidence Imprinted Gene Candidates

  year unknowncites this paper