Toxicity profile of ethanolic extract of Azadirachta indica stem bark in male Wistar rats.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Asian Pacific Journal of Tropical Biomedicine

• Publication date

  2012-10-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/S2221-1691(12)60234-2PMID 23569852PMCID PMC3609225
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cytotoxic and antioxidant activity of selected marine sponges

  2012cited by this paper
• Estimation of total phenolic content, cytotoxicity and in–vitro antioxidant activity of stem bark of Moringa oleifera

  2012cited by this paper
• In-vitro cytotoxic activity of β-Sitosterol triacontenate isolated from Capparis decidua (Forsk.) Edgew.

  2012cited by this paper
• Evaluation of the acute and sub acute toxicity of Annona senegalensis root bark extracts.

  2012cited by this paper
• Acute and subacute oral toxicity evaluation of Tephrosia purpurea extract in rodents

  2012cited by this paper
• A bioactive flavonoid from Pavetta crassipes

  2011cited by this paper
• Antimicrobial activity, cytotoxicity, and phytochemical screening of Voacanga globosa (Blanco) Merr. leaf extract (Apocynaceae).

  2011cited by this paper
• Effect of Cassava Based Diet On Hepatic Proteins In Albino Rats Fed With Crude Oil Contaminated Diet

  2011cited by this paper
• A bioactive flavonoid from Pavetta crassipes K. Schum

  2011cited by this paper
• Method of LDL Cholesterol Measurement Influences Classification of LDL Cholesterol Treatment Goals

  2010cited by this paper
• Enzyme activities and histopathology of selected tissues in rats treated with potassium bromate.

  2010cited by this paper
• Effect of aqueous extract of Leonotis leonurus (L.) R. Br. leaves in male Wistar rats

  2010cited by this paper
• Toxicological evaluation of aqueous leaf and berry extracts of Phytolacca dioica L. in male Wistar rats.

  2010cited by this paper
• Toxicity and potential anti-trypanosomal activity of ethanolic extract of Azadirachta indica (Maliacea) stem bark: an in vivo and in vitro approach using Trypanosoma brucei.

  2010cited by this paper
• Some liver function indices and blood parameters in T. brucei -infected rats treated with honey

  2010cited by this paper
• Hepatoprotective activity of methanolic and aqueous extracts of Azadirchata indica leaves.

  2010cited by this paper
• Effect of Neem Oil on Sperm Mitochondrial Activity

  2010cited by this paper
• Pharmacological activity, phytochemical analysis and toxicity of methanol extract of Etlingera elatior (torch ginger) flowers

  2010cited by this paper
• Influence of extraction methods on the hepatotoxicity of Azadirachta indica bark extract on albino rats

  2009cited by this paper
• Effect of temozolomide treatment on the adenine nucleotide hydrolysis in blood serum of rats with implanted gliomas

  2009cited by this paper
• Studies on Anti-inflammatory, Antinociceptive and Antipyretic Activities of Ethanol Extract of Azadirachta indica Leaves

  2009cited by this paper
• Antioxidant activity and quantitative estimation of azadirachtin and nimbin in Azadirachta Indica A. Juss grown in foothills of Nepal

  2009cited by this paper
• Chemoprevention of rat mammary carcinogenesis by Azadirachta indica leaf fractions: modulation of hormone status, xenobiotic-metabolizing enzymes, oxidative stress, cell proliferation and apoptosis.

  2009cited by this paper
• A study on the hypoglycemic and hypolipidemic effects of an ayurvedic drug Rajanyamalakadi in diabetic patients

  2009cited by this paper
• Effect of Bulbine natalensis Baker Stem Extract on the Functional Indices and Histology of the Liver and Kidney of Male Wistar Rats

  2009cited by this paper
• Toxicological implications of aqueous extract of Bambusa vulgaris leaves in pregnant Dutch rabbits

  2009cited by this paper
• Androgenic potentials of aqueous extract of Massularia acuminata (G. Don) Bullock ex Hoyl. stem in male Wistar rats.

  2008cited by this paper
• Toxicological screening of traditional medicine Laghupatha (Cissampelos pareira) in experimental animals.

  2008cited by this paper
• The Antidiabetic Efficacy of Combined Extracts from Two Continental Plants: Azadirachta indica (A. Juss) (Neem) and Vernonia amygdalina (Del.) (African Bitter Leaf)

  2008cited by this paper
• Alterations in Serum Lipid Profile of Male Rats by Oral Administration of Aqueous Extract of Fadogia agrestis Stem

  2008cited by this paper
• Hematological evaluation in male albino rats following chronic administration of aqueous extract of Fadogia agrestis stem

  2007cited by this paper
• Safety of Traditional Arab Herbal Medicine

  2006cited by this paper
• Tolerance of New Zealand White and Californian doe rabbits at first parity to the sub-tropical environment of Egypt

  2006cited by this paper
• Modern phytomedicine: Turning Medicinal Plants into Drugs

  2006cited by this paper
• Increased liver alkaline phosphatase and aminotransferase activities following administration of ethanolic extract of Khaya senegalensis stem bark to rats

  2005cited by this paper
• Antioxidant activity of Siamese neem tree (VP1209).

  2005cited by this paper
• Effect of ethanolic extract of Bougainvillea spectabilis leaves on haematological and serum lipid variables in rats

  2005cited by this paper
• Protective role of extracts of neem seeds in diabetes caused by streptozotocin in rats.

  2004cited by this paper
• Importance of LDL/HDL cholesterol ratio as a predictor for coronary heart disease events in patients with heterozygous familial hypercholesterolaemia: a 15-year follow-up (1987-2002)

  2003cited by this paper
• Concordance of the toxicity of pharmaceuticals in humans and in animals.

  2000cited by this paper
• Principles of Toxicology

  1997cited by this paper
• Albumin standards and the measurement of serum albumin with bromcresol green.

  1997cited by this paper
• Non-hormonal post-coital contraceptive action of neem oil in rats.

  1988cited by this paper
• The New England Journal of Medicine, Volume 276, January 19, 1967: Fat transport in lipoproteins--an integrated approach to mechanisms and disorders. By Donald S. Fredrickson, Robert I. Levy, Robert S. Lees.

  1987cited by this paper
• Clinical Guide to Laboratory Tests

  1984cited by this paper
• Casarett and Doull's Toxicology. The Basic Science of Poisons

  1981cited by this paper
• Quantitation of high density lipoproteins

  1978cited by this paper
• Enzymes in rat urine: alkaline phosphatase.

  1972cited by this paper
• Enzymes in rat urine: alkaline phosphatase.

  1972cited by this paper
• Fat transport in lipoproteins--an integrated approach to mechanisms and disorders.

  1967cited by this paper
• Fat transport in lipoproteins--an integrated approach to mechanisms and disorders.

  1967cited by this paper
• Determination of serum proteins by means of the biuret reaction.

  1949cited by this paper
• The plasma proteins.

  1947cited by this paper

• Evaluation of Paederia foetida L. Extract on Liver Weight Alterations in an Escherichia coli Sepsis Mouse Model

  2025cites this paper
• An Ethnobotanical Survey and Pharmacological and Toxicity Review of Medicinal Plants Used in the Management of Obesity in the North Central Zone of Nigeria

  2025cites this paper
• Traditional to modern perspectives on Neem (Azadirachta indica): A gateway to bioactive compounds, sustainable agrochemicals and industrial applications

  2025cites this paper
• Cardioprotective Potentials of Aqueous Whole Plant Extract of Phyllanthus niruri on Heavy Metal Toxicity Induced in Wistar Albino Rats

  2025cites this paper
• Quassiaamara Linn. (Simaroubaceae): phytochemical composition and biopesticidal potential

  2025cites this paper
• Exploring Bioactive Phytomedicines for Advancing Pulmonary Infection Management: Insights and Future Prospects

  2024cites this paper
• Toward a greener multifunctional pharmaceutical excipient: in vivo safety evaluation of nanofibrillated cellulose from tobacco stalk

  2024cites this paper
• Natural pesticide, Azadirachta indica A.Juss. (Neem), disrupted reproductive parameters of male rats.

  2024cites this paper
• Nanoemulsion‐based transdermal delivery of third‐generation steroidal and non‐steroidal aromatase inhibitors in preclinical models

  2024cites this paper
• An Investigation into the Acute and Subacute Toxicity of Extracts of Cassipourea flanaganii Stem Bark In Vivo

  2023cites this paper
• Pharmacognosy of Azadirachta indica and possible use in COVID- 19: a review

  2023cites this paper
• Dermal repeated dose toxicity study of the anti-breast cancer drug Formestane cream in Bama minipig.

  2023cites this paper
• Histological, haematological, and thyroid hormones toxicity of female rats orally exposed to CuO/ZnO core/shell nanoparticles synthesized by Ar plasma jets

  2023influential citation
• A Systematic Review of Medicinal Plants of Kenya used in the Management of Bacterial Infections

  2022cites this paper
• Evaluation of the toxic effects of the aqueous extract of Niprineem tea in mice and rats

  2022cites this paper
• Metabolic profile, antimicrobial and toxicity evaluation of Azadirachta indica roots

  2022cites this paper
• Estimation of in vivo toxicity of MgO/ZnO core/shell nanoparticles synthesized by eco-friendly non-thermal plasma technology

  2022cites this paper
• Moringa oleifera extract regulates the expression of some sickle cell related genes in normal Wistar rats

  2022cites this paper
• Medicinal plants of the African traditional pharmacopoeia in the management of bovine trypanosomosis: A review

  2022influential citation
• A safety profile of aqueous methanol aerial extract of Alysicarpus glumaceus in mice: acute and subacute administration

  2022cites this paper
• The Antimicrobial Potential of the Neem Tree Azadirachta indica

  2022cites this paper
• MULTIPLICIDADE DAS CIÊNCIAS AGRÁRIAS VOLUME 2

  2022cites this paper
• A review of medicinal plant-based bioactive electrospun nano fibrous wound dressings

  2021cites this paper
• Potential of Ethanol Extracted Secondary Metabolites of Plants from Thal Desert (Pakistan) for In vitro Changes in Haematological Indices

  2021cites this paper
• Toxicity of monosodium glutamate on liver and body weight with the protective effect of tannic acid in adult male rats

  2021cites this paper
• ANIMAL MODEL ASSESSMENT OF THE BIOCHEMICAL EFFECT OF ADMINISTRATION OF AQUEOUS EXTRACTS OF A. INDICA STEM BARK

  2021cites this paper
• Azadirachta indica A. Juss. In Vivo Toxicity—An Updated Review

  2021cites this paper
• Acute Toxicological Assessment and Investigation of Cardioprotective Potential of Processed Pumpkin (Cucurbita Maxima) Seed Flour

  2021cites this paper
• Preclinical Trial of Traditional Plant Remedies for the Treatment of Complications of Gestational Malaria

  2021cites this paper
• Traditional medicinal plants used for treating emerging and re-emerging viral diseases in northern Nigeria

  2021cites this paper
• Hematological Alterations Induced by Zinc Oxide Nanoparticles and Preventive Role of Moringa Oleifera: In vivo

  2021cites this paper
• In Vivo Antiplasmodial Activity of Detarium microcarpum (Fabaceae) Stem Bark Extract

  2021cites this paper
• Safety Evaluation of Crude Ethanol Extract of Waltheria Indica Linn. Root In Male Wistar Rats

  2021cites this paper
• Protective effect of isosteviol sodium against LPS-induced multiple organ injury by regulating of glycerophospholipid metabolism and reducing macrophage-driven inflammation.

  2021cites this paper
• In vitro Antisickling and Sub Chronic Toxicity Studies of the Ethanol Extract of Cnidoscolus aconitifolius in Wistar Rats

  2020cites this paper
• Evaluating bioactive constituents and toxicological effects of aqueous extract of fermented Pentaclethra macrophylla seeds in rats

  2020cites this paper
• Hematological and biochemical effects of Morinda lucida and Alstonia boonei on the liver and kidney of mice infected with Plasmodium berghei

  2020cites this paper
• Comparative Study on Toxicity of Synthetic Pyrethroids And Azadirachtin Insecticides in Experimental Rats

  2020cites this paper
• Struktur Hepar dan Rasio Bobot Hepar Terhadap Bobot Tubuh Mencit (Mus Musculus L.) Jantan Setelah Pemberian Ekstrak Etanol Daun Mimba (Azadirachta Indica A.Juss)

  2020cites this paper
• Hematological and histological effect of fractionated neem leaf extract in healthy Wistar rats

  2020cites this paper
• A review for selecting medicinal plants commonly used for malaria in Uganda

  2020cites this paper
• In vivo Antimalarial Activities of Five Ugandan Medicinal Plants on Plasmodium berghei in Mice

  2020cites this paper
• Mitigation of Arsenic-induced Increases in Pro-Inflammatory Cytokines and Haematological Derangements by Ethanol Leaf Extract of Irvingia gabonensis

  2020cites this paper
• Morphophysiological Changes in the Liver of Wistar Rats Exposed to Acute and Chronic Concentrations of Vitellaria paradoxa

  2020cites this paper
• Nanotechnology improves the therapeutic efficacy of gemcitabine against a human hepatocellular carcinoma cell line and minimizes its in vivo side effects

  2020cites this paper
• Biochemical and Histopathological Effect of Detarium microcarpum Stem Bark Extract in Wistar Albino Rats

  2020cites this paper
• Toxic effect of different neem formulations against pests and mammals

  2020influential citation
• Biochemical and toxicological effects of methanolic extract of Asparagus africanus Lam in Sprague-Dawley rats

  2020cites this paper
• Azadirachta indica A. Juss. (Meliaceae)

  2020cites this paper
• Acute and subacute toxicity evaluation of hydroalcoholic extract of Caryota urens leaves in Wistar rats

  2020cites this paper
• Safety evaluation of chromium picolinate in experimental rats

  2019cites this paper
• Water Extract of Acori Graminei Rhizoma Attenuates Features of Rheumatoid Arthritis in DBA/1 Mice

  2019cites this paper
• In vitro and in vivo toxicity assessment of biologically synthesized silver nanoparticles from Elaeodendron croceum

  2019cites this paper
• High dose of standardised extract of Costus afer leaves potentiates cadmium reproductive toxicity in Wistar rats

  2019cites this paper
• New biological trends on cell and callus growth and azadirachtin production in Azadirachta indica

  2019cites this paper
• The Activity of D-Limonene from Sweet Orange Peel (Citrus Sinensis L.) Exctract as a Natural Insecticide Controller of Bedbugs (Cimex cimicidae)

  2019cites this paper
• Evaluation of Sub-acute and Sub Chronic Toxicity Profile of the Aqueous Leaf Crude Extract of Melanthera Scandens (Schumach & Thonn) in Wistar Rats

  2019cites this paper
• Neem leaves extract (Azadirachta indica A. Juss) on male reproductive system: a mini-review

  2019cites this paper
• Toxicity of Antidiarrheal and Spasmolytic Herbal Mixtures Used in Neonates and Infants less than Six Months of Age in Young Rodents

  2019cites this paper
• TOXICOLOGICAL EVALUATION OF MAGNESIUM HYDROXIDE NANOPARTICLES IN RATS FOLLOWING 28 DAYS OF REPEATED ORAL EXPOSURE

  2018influential citation
• Bobot Badan Mencit (Mus musculus L.) setelah Pemberian Ekstrak Ethanol Daun Nimba (Azadirachta indica) Secara Oral Selama 21 Hari

  2018cites this paper
• In vitro bioactivities and subacute toxicity study of O. basilicum, T. vulgaris and R. officinalis

  2018cites this paper
• Subacute Oral Toxicity Assesment of Ethanol Extract of Mariposa christia vespertilionis Leaves in Male Sprague Dawley Rats

  2018cites this paper
• A comprehensive review of phytochemical profile, bioactives for pharmaceuticals, and pharmacological attributes of Azadirachta indica

  2018influential citation
• Acute and chronic toxicity profiles of the methanol leaf extract of Acacia ataxacantha D.C (Leguminosae) in Wistar rats

  2018cites this paper
• Ethnobotanical study of medicinal plants from Ghana; confirmation of ethnobotanical uses, and review of biological and toxicological studies on medicinal plants used in Apra Hills Sacred Grove

  2018cites this paper
• Effects of Cysteine-Stabilised Peptide Fraction of Aqueous Extract of Morinda lucida Leaf on Selected Cardiovascular Disease Indices in Mice

  2018cites this paper
• Antinociceptive activity of ethanolic extract of Azadirachta indica A. Juss (Neem, Meliaceae) fruit through opioid, glutamatergic and acid-sensitive ion pathways in adult zebrafish (Danio rerio).

  2018cites this paper
• Evaluation of Curcuma zerumbet (Zingibaraceae) rhizome extracts sub-acute toxicity on Wistar rats

  2018cites this paper
• Evaluation of the toxicity of Colocasia esculenta (Aracaceae): Preliminary study of leaves infected by Phytophthora colocasiae on wistar albinos rats.

  2018cites this paper
• In Vitro Antimicrobial Efficacy of Individual and Combined Extracts Of Five Medicinal Plants, Enantia chlorantha, Echinacea angustifolia, Acalypha indica, Alchemilla vulgaris, and Vernonia guineensis on Strains of Salmonella typhi

  2018cites this paper
• ANTIOXIDANT ACTIVITY AND TOXICITY EFFECT OF ELEVEN TYPES OF BARK EXTRACTS ACQUIRED FROM EUPHORBIACEAE

  2018cites this paper
• Effect of ethanolic Neem (Azadirachta indica) leaf extract as an herb contraceptive on Hepato-somatic Index of the male mice (Mus musculus)

  2018cites this paper
• Hematological, antioxidant and protective performance of Usnea longissima on chemical induced hepatotoxicity in experimental animals

  2017cites this paper
• Innocuousness of a polyherbal formulation: A case study using a traditional Thai antihypertensive herbal recipe in rodents.

  2017cites this paper
• Functional Assessments and Histopathology of Hepatorenal Tissues of Wistar Rats Infused with Carbon Tetrachloride and Treated with Raw and Hydrothermal Processed Herbs

  2017cites this paper
• Functional assessments and histopathology of hepatorenal tissues of rats treated with raw and processed herbs

  2017cites this paper
• Antibacterial activities of medicinal plants used in Mexican traditional medicine.

  2017cites this paper
• Toxicological evaluation of the aqueous extract of Pseudocedrela kotschyi (Meliaceae) stem bark in albino rats

  2017cites this paper
• Effect of Acute Doses of Magnesium Hydroxide Nanoparticles on Some Biochemical Parameters of Wistar Rats

  2017cites this paper
• Preliminary studies of acute and sub-chronic toxicity of the aqueous extract of Guibourtia tessmannii (Harms) J. Leonard stem barks (Caesalpiniaceae) in mice and rats

  2016cites this paper
• UHPLC-MS/SRM method for quantification of neem metabolites from leaf extracts of Meliaceae family plants

  2016cites this paper
• Levels of Acute Blood Indices Disarrangement and Organ Weights of Wistar Rats Fed with Flavour Enhancer- and Contraceptive-Containing Diets

  2016influential citation
• Effects of diet containing monosodium glutamate on organ weights, acute blood steroidal sex hormone levels, lipid profile and erythrocyte antioxidant enzymes activities of rats

  2016cites this paper
• Acute Toxicity (LD50) of Petroleum Ether, Ethanolic and Aqueous Stem Bark Extracts of Adansonia digitata on Albino Wister Rat

  2016cites this paper
• Blood Profiles and Histopathological Changes of Liver and Kidney Tissues from Male Sprague Dawley Rats Treated with Ethanol Extracts of Clinacanthus nutans Leaf.

  2016cites this paper
• Toxicological assessment of the aqueous dried leaf extracts of Senna alata L. in wistar rats

  2016cites this paper
• Anti-inflammatory and toxicological evaluation of Moussonia deppeana (Schldl. & Cham) Hanst and Verbascoside as a main active metabolite.

  2016cites this paper
• Hematological Markers of In Vivo Toxicity

  2016cites this paper
• Toxicity Evaluation of the Aqueous Stem Extracts of Senna alata in Wistar Rats

  2016cites this paper
• Toxicological implications and laxative potential of ethanol root extract of Morella serrata in loperamide-induced constipated Wistar rats

  2016cites this paper
• Acute and Sub-acute Toxicity Profile of Aqueous Leaf Extract of Nymphaea lotus Linn (Nymphaeaceae) in Wistar Rats

  2015cites this paper
• The Global Picture

  2015cites this paper
• Toxicological Evaluations of the Crude Extracts and Fractions of Moringastenopetala Leaves in Liver and Kidney of Rats

  2015cites this paper
• Toxicological evaluations of Stigma maydis (corn silk) aqueous extract on hematological and lipid parameters in Wistar rats

  2015cites this paper
• Ethnobotanical study of Loloh: Traditional herbal drinks from Bali (Indonesia).

  2015cites this paper
• Antiatherogenic and Cardioprotective Effects of Black Chokeberry (Aronia melanocarpa) Juice in Aging Rats

  2015cites this paper
• Antihyperglycemic and subchronic toxicity study of Moringa stenopetala leaves in mice

  2014cites this paper
• Ethnomedicinal plants used to treat skin diseases by Tharu community of district Udham Singh Nagar, Uttarakhand, India.

  2014cites this paper
• Biochemical Parameters in Toxicological Studies in Africa: Significance, Principle of Methods, Data Interpretation, and Use in Plant Screenings

  2014cites this paper