Therapeutic defibrination in the treatment of thrombotic disease.

No abstract is available for this paper.

• Publication year

  1968

• Venue

  The Lancet

• Publication date

  1968-03-09

• Fields of study

  Medicine

• Identifiers
  DOI 10.1016/S0140-6736(68)91465-7PMID 4170831
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• MICROANGIOPATHIC HÆMOLYTIC ANÆMIA

  1967cited by this paper
• The Isolation and Properties of the Thrombin‐like Activity from Ancistrodon rhodostoma Venom

  1967cited by this paper
• Experimental production of microangiopathic haemolytic anaemia in vivo.

  1967cited by this paper
• Microangiopathic hemolytic anemia.

  1967cited by this paper
• In vivo effects of Agkistrodon rhodostoma venom: studies with fibrinogen-131I.

  1966cited by this paper
• Quantitative estimation of split products of fibrinogen in human serum, relation to diagnosis and treatment.

  1966cited by this paper
• Increased platelet adhesiveness in recurrent venous thrombosis and pulmonary embolism.

  1965cited by this paper
• A Study of the Coagulant Properties of Malayan Pit‐Viper Venom

  1965cited by this paper
• A Study of the Coagulant Action of Eight Snake Venoms

  1964cited by this paper
• Prolonged coagulation defect (defibrination syndrome) in Malayan viper bite.

  1963cited by this paper
• Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

  1962cited by this paper
• The mechanism of clot dissolution by plasmin.

  1959cited by this paper
• Human Blood Coagulation and its Disorders

  1958cited by this paper
• Defibrination syndrome in pregnancy: value of various diagnostic tests.

  1958cited by this paper
• A modification of the benzidine method for measurement of hemoglobin in plasma and urine.

  1956cited by this paper
• The fibrin plate method for estimating fibrinolytic activity.

  1952cited by this paper
• A new method for the determination of fibrinogen in small samples of plasma.

  1951cited by this paper
• Morphology and enumeration of human blood platelets.

  1950cited by this paper

• Disseminated intravascular coagulation.

  2019cites this paper
• Experimental Dysfibrinogenemia : In Vivo Studies

  2017cites this paper
• 51 – Intravenous Thrombolysis

  2016cites this paper
• Antithrombotic Drugs: Part II

  2012cites this paper
• Ancrod in the Treatment of Acute Ischaemic Stroke

  2012cites this paper
• Anticoagulant and Thrombolytic Drugs I: Patho-Physiological and Pharmacological Aspects

  2012cites this paper
• Advances in thrombolytics for treatment of acute ischemic stroke

  2012cites this paper
• Antithrombotic Drugs: Part I

  2012cites this paper
• Anticoagulant and Thrombolytic Drugs II: Clinical Aspects

  2012cites this paper
• 49 – Intravenous Thrombolysis

  2011cites this paper
• Successfully treated priapism in acute myeloblastic leukemia complicating Hodgkin's disease.

  2009cites this paper
• Coagulation studies in patients treated with defibrase.

  2009cites this paper
• A BRIEF HISTORY OF SNAKE VENOMS AFFECTING HEMOSTASIS

  2006cites this paper
• Intravenous ancrod for acute ischaemic stroke in the European Stroke Treatment with Ancrod Trial: a randomised controlled trial.

  2006cites this paper
• Advances in thrombolytics and mechanical devices for treatment of acute ischemic stroke

  2005cites this paper
• Heparin-induced thrombocytopenia in the cardiovascular patient: diagnostic and treatment guidelines.

  2005cites this paper
• The prothrombin-activating principle from Echis carinatus venom

  2004cites this paper
• The prothrombin-activating principle from Echis carinatus venom

  2004cites this paper
• Can the Time Window for Administration of Thrombolytics in Stroke be Increased?

  2003cites this paper
• Stroke--acute interventions.

  2002cites this paper
• A new vascular sealant (Sealgel) to achieve rapid hemostasis after percutaneous angioplasty in anticoagulated patients: clinical feasibility and preliminary results

  2001cites this paper
• Heparin-induced thrombocytopenia.

  2001cites this paper
• Intravenous ancrod for treatment of acute ischemic stroke: the STAT study: a randomized controlled trial. Stroke Treatment with Ancrod Trial.

  2000cites this paper
• The interaction of ancrod with human platelets.

  1999cites this paper
• Anticoagulant therapy in unstable angina.

  1999cites this paper
• Ancrod in the Treatment of Acute Ischemic Stroke

  1998cites this paper
• Ancrod reduces intracerebral hemorrhage quantified in vivo by magnetic resonance imaging in rats.

  1998cites this paper
• Heparin-induced thrombocytopenia.

  1998cites this paper
• Hugh Alistair Reid OBE MD: investigation and treatment of snake bite.

  1998cites this paper
• Therapeutic Potential of Ancrod in the Management of Cerebrovascular Disorders

  1998cites this paper
• Characterization of three endogenous peptide inhibitors for multiple metalloproteinases with fibrinogenolytic activity from the venom of Taiwan habu (Trimeresurus mucrosquamatus).

  1998cites this paper
• Pharmacological approaches and strategies for therapeutic modulation of fibrinogen.

  1997cites this paper
• Defibrinogenating Enzymes

  1997cites this paper
• Synergism of procoagulation effect of thrombin-like enzymes from Dienagkistrodon acutus and Agkistrodon halys snake venoms.

  1996cites this paper
• Arterial Thrombosis Enhanced by an Acute Phase Response

  1996cites this paper
• Heparin-induced thrombocytopenia.

  1996cites this paper
• Characterization of a thrombin-like enzyme, grambin, from the venom of Trimeresurus gramineus and its in vivo antithrombotic effect.

  1995cites this paper
• Characterization of multiple metalloproteinases with fibrinogenolytic activity from the venom of Taiwan habu (Trimeresurus mucrosquamatus): protein microsequencing coupled with cDNA sequence analysis.

  1995cites this paper
• The antiplatelet activity of ancrod on administration to rabbits.

  1995cites this paper
• Ancrod for the Treatment of Acute Ischemic Brain Infarction

  1994cites this paper
• In vivo effect of a thrombin-like enzyme on platelet plug formation induced in mesenteric microvessels of mice.

  1994cites this paper
• Characterization of one novel venom protease with beta-fibrinogenase activity from the Taiwan habu (Trimeresurus mucrosquamatus): purification and cDNA sequence analysis.

  1994cites this paper
• Isolation of multiple isoforms of alpha-fibrinogenase from the Western diamondback rattlesnake, Crotalus atrox: N-terminal sequence homology with ancrod, an antithrombotic agent from Malayan viper.

  1994cites this paper
• Characterization of three fibrinogenolytic proteases isolated from the venom of Taiwan habu (Trimeresurus mucrosquamatus).

  1993cites this paper
• Thrombolytic Therapy: A Comprehensive Review of Its Use in Clinical Medicine. Part II

  1993cites this paper
• Ancrod versus heparin for anticoagulation during vascular surgical procedures.

  1993cites this paper
• Antiplatelet Activity of a Thrombin-Like Enzyme in Experimental Rabbits

  1993cites this paper
• Anticoagulant therapy with ancrod.

  1993cites this paper
• Thrombolytic Therapy: A Comprehensive Review of its Use in Clinical Medicine—Part I

  1993cites this paper
• Isolation of a crotalase-like protease with alpha-fibrinogenase activity from the western diamondback rattlesnake, Crotalus atrox.

  1992cites this paper
• Physiologic alteration of fibrinogen levels: Influence upon patency of microvenous anastomoses

  1992cites this paper
• Characterization of a protease with alpha- and beta-fibrinogenase activity from the Western diamondback rattlesnake, Crotalus atrox.

  1992cites this paper
• Characterization of a protease with α- and β-fibrinogenase activity from the western diamondback rattlesnake, crotalus atrox

  1992cites this paper
• Effects of ancrod and rtPA on fibrin accumulation, glomerular inflammation and renal function in nephrotoxic nephritis.

  1991cites this paper
• Rapid anticoagulation using ancrod for heparin-induced thrombocytopenia.

  1991cites this paper
• Ancrod causes rapid thrombolysis in patients with acute stroke.

  1990cites this paper
• In vivo defibrination results in markedly decreased amounts of fibrinogen in rat megakaryocytes and platelets.

  1990cites this paper
• Effect of snake venom of Agkistrodon halys on atherosclerosis and blood characteristics in Japanese quail.

  1990cites this paper
• Primary Pharmacotherapy other than Prostanoids

  1990cites this paper
• Therapeutic defibrination with ancrod does not protect canine myocardium from reperfusion injury.

  1990cites this paper
• Ancrod vs. Heparin: The Resulting Effect on Oxygenator Performance During Routine Cardiopulmonary Bypass

  1989cites this paper
• Ancrod (Arvin) as an alternative to heparin anticoagulation for cardiopulmonary bypass.

  1989cites this paper
• Dissimilar systemic and local adverse effects of thrombolytic therapy.

  1988cites this paper
• Heparin-associated thrombocytopenia and thrombosis.

  1988cites this paper
• Use of ancrod in acute or progressing ischemic cerebral infarction.

  1988cites this paper
• Thrombolytic therapy: current status (1).

  1988cites this paper
• Thrombolytic Therapy: Current Status

  1988cites this paper
• Fibrinolysis in glomerulonephritis treated with ancrod: renal functional, immunologic and histopathologic effects.

  1988cites this paper
• Effect of Fibrinogen-clotting Enzymes on Secretion of Plasminogen Activators from Cultured Human Endothelial Cells

  1988cites this paper
• Unresolved clinical pharmacologic questions in thrombolytic therapy for acute myocardial infarction.

  1988cites this paper
• Ancrod: a practical alternative to heparin.

  1988cites this paper
• Appraisal of various thrombolytic agents in the treatment of acute myocardial infarction.

  1987cites this paper
• Ancrod decreases the frequency of cyclic flow variations and causes thrombolysis following acute coronary thrombosis.

  1987cites this paper
• Ancrod: normalization of fibrinolytic enzyme abnormalities in patients with systemic lupus erythematosus and lupus nephritis.

  1985cites this paper
• Blood Coagulation and Fibrinolysis

  1985cites this paper
• Ancrod in systemic lupus erythematosus with thrombosis. Clinical and fibrinolysis effects.

  1984cites this paper
• [Role of heparin in inhibiting fibrin formation].

  1984cites this paper
• [Pure defibrination after timber rattlesnake bite].

  1983cites this paper
• [Fibrinolytic and defibrinogenation therapy].

  1983cites this paper
• alpha-Fibrinogenase from Agkistrodon rhodostoma (Malayan pit viper) snake venom.

  1983cites this paper
• Defibrination with ancrod: effect on reticuloendothelial clearance of circulating immune complexes.

  1982cites this paper
• Thrombin-like and fibrinolytic enzymes in the venoms from the Gaboon viper (Bitis gabonica), eastern cottonmouth moccasin (Agkistrodon p. piscivorus) and southern copperhead (Agkistrodon c. contortrix) snakes.

  1982cites this paper
• Thrombosis" mechanisms the relationship of hemostatic to drug therapy

  1981cites this paper
• Fibrinolytic and fibrinogen clotting enzymes present in the venoms of western diamondback rattlesnake, Crotalus atrox, eastern diamondback rattlesnake, Crotalus adamanteus, and southern Pacific rattlesnake, Crotalus viridis helleri.

  1981cites this paper
• Thrombosis: the relationship of hemostatic mechanisms to drug therapy.

  1981cites this paper
• [Effect of snake venom, Defibrase, on haemostasis (author's transl)].

  1980cites this paper
• The influence of drugs on disseminated intravascular coagulation (DIC). IV. Effects on the thrombin-like enzyme batroxobin on thrombin-induced DIC in rats.

  1980cites this paper
• Fibrinolytic enzyme(s) in western diamondback rattlesnake (Crotalus atrox) venom.

  1980cites this paper
• Stimulation of fibrinogen synthesis: a possible functional role of fibrinogen degradation products.

  1980cites this paper
• Effect of defibrinogenation on lung water accumulation after pulmonary microembolism in dogs.

  1980cites this paper
• Shedding from the cell surface of normal and cancer cells.

  1980cites this paper
• Effect of defibrination with batroxobin on growth and metastasis of JW sarcoma in mice.

  1980cites this paper
• A comparison of biological and chemical properties of three North American (Crotalidae) snake venoms.

  1979cites this paper
• Effect of low fibrinogen concentrations on the rheology of human blood in vitro.

  1979cites this paper
• The effect of homologous thrombin and fibrinogen degradation products on fibrinogen synthesis in rabbits.

  1979cites this paper
• Snake Venoms and Blood Coagulation

  1979cites this paper
• The clotting activity of the thrombin-like enzyme of Agkistrodon acutus (hundred-pace snake) venom.

  1979cites this paper
• Regulation of fibrinogen biosynthesis: effect of fibrin degradation products, low-molecular-weight peptides of fibrinogenolysis, and fibrinopeptides A and B.

  1979cites this paper
• Drugs affecting blood clotting, fibrinolysis and haemostasis

  1978cites this paper
• Coagulation for cardiologists.

  1978cites this paper