Kinesin-3 and dynein cooperate in long-range retrograde endosome motility along a nonuniform microtubule array

We studied molecular motors in long-range motility of early endosomes (EEs) in a fungal model system that contains a bipolar, dendrite-like microtubule (MT) array. Dynein moves retrograde EEs over ∼10 μm, before kinesin-3 takes over for a further ∼80 μm along antipolar MT bundles. Thus kinesin-3 is the major motor for retrograde EE motility.

• Publication year

  2011

• Venue

  Molecular Biology of the Cell

• Publication date

  2011-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1091/mbc.E11-03-0217PMID 21832152PMCID 3183019
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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