Metal Based Compounds, Modulators of Na, K-ATPase with Anticancer Activity

No abstract is available for this paper.

• Publication year

  2016

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1007/978-3-319-24750-2_24
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Na+/K+-ATPase

  2020cited by this paper
• Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells

  2014cited by this paper
• Anti-cancer palladium complexes: a focus on PdX2L2, palladacycles and related complexes.

  2014cited by this paper
• Inhibition of Na(+)/K(+)-ATPase and cytotoxicity of a few selected gold(III) complexes.

  2014cited by this paper
• Gold(III) complexes in medicinal chemistry.

  2014cited by this paper
• Nedaplatin: a cisplatin derivative in cancer chemotherapy

  2013cited by this paper
• In vitro effects of some gold complexes on Na(+)/K(+) ATPase activity and cell proliferation.

  2013cited by this paper
• The contrasting activity of iodido versus chlorido ruthenium and osmium arene azo- and imino-pyridine anticancer complexes: control of cell selectivity, cross-resistance, p53 dependence, and apoptosis pathway.

  2013cited by this paper
• Preclinical Perspectives on Platinum Resistance

  2012cited by this paper
• Erratum to “Decreased Phosphorylation and Increased Methionine Oxidation of α-Synuclein in the Methionine Sulfoxide Reductase A Knockout Mouse”

  2012cited by this paper
• Contrasting cellular uptake pathways for chlorido and iodido iminopyridine ruthenium arene anticancer complexes.

  2012cited by this paper
• Glutathione Homeostasis and Functions: Potential Targets for Medical Interventions

  2012cited by this paper
• Approaching tumour therapy beyond platinum drugs: status of the art and perspectives of ruthenium drug candidates.

  2012cited by this paper
• Platinum anticancer drugs. From serendipity to rational design.

  2011cited by this paper
• Anticancer Activity of Metal Complexes: Involvement of Redox Processes

  2011cited by this paper
• Comparison of liposomal cisplatin versus cisplatin in non-squamous cell non-small-cell lung cancer

  2011cited by this paper
• Anti-cancer activity of a novel palladium(II) complex on human breast cancer cells in vitro and in vivo.

  2011cited by this paper
• Polynuclear ruthenium, osmium and gold complexes. The quest for innovative anticancer chemotherapeutics.

  2011cited by this paper
• Liposomal cisplatin: a new cisplatin formulation

  2010cited by this paper
• Targeting the Na(+)/K(+)-ATPase alpha1 subunit of hepatoma HepG2 cell line to induce apoptosis and cell cycle arresting.

  2010cited by this paper
• Arene ruthenium complexes as anticancer agents.

  2010cited by this paper
• Synthesis, characterisation and biological properties of gold(III) compounds with modified bipyridine and bipyridylamine ligands.

  2010cited by this paper
• Synthesis, crystal structures and anticancer activities of two decavanadate compounds

  2010cited by this paper
• Mechanism of complex formation between [AuCl4]− and l-methionine

  2009cited by this paper
• ProLindac (AP5346): a review of the development of an HPMA DACH platinum Polymer Therapeutic.

  2009cited by this paper
• Controlling Platinum, Ruthenium and Osmium Reactivity for Anticancer Drug Design.

  2009cited by this paper
• Interaction of the [PtCl2(DMSO)2] Complex with L-Cysteine

  2009cited by this paper
• Synthesis and biological evaluation of decavanadate Na4Co(H2O)6V10O28.18H2O.

  2009cited by this paper
• The tumor proteasome as a novel target for gold(III) complexes: implications for breast cancer therapy.

  2009cited by this paper
• On the medicinal chemistry of gold complexes as anticancer drugs

  2009cited by this paper
• Proteins as possible targets for antitumor metal complexes: biophysical studies of their interactions

  2009cited by this paper
• Influence of decavanadate on rat synaptic plasma membrane ATPases activity.

  2009cited by this paper
• The role of cellular accumulation in determining sensitivity to platinum-based chemotherapy.

  2008cited by this paper
• The sodium pump alpha1 subunit as a potential target to combat apoptosis-resistant glioblastomas.

  2008cited by this paper
• Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action.

  2008cited by this paper
• Antitumour metal compounds: more than theme and variations.

  2008cited by this paper
• Novel therapeutic applications of cardiac glycosides

  2008cited by this paper
• Na,K-adenosine triphosphatase alpha1-subunit predicts survival of renal clear cell carcinoma.

  2008cited by this paper
• Gold complexes as prospective metal-based anticancer drugs.

  2008cited by this paper
• Palladium-based chemotherapeutic agents: Routes toward complexes with good antitumor activity

  2008cited by this paper
• Na+/K+-ATPase α subunits as new targets in anticancer therapy

  2008cited by this paper
• KP1019, A New Redox‐Active Anticancer Agent – Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

  2008cited by this paper
• Pharmacokinetics of low-dose nedaplatin and validation of AUC prediction in patients with non-small-cell lung carcinoma

  2007cited by this paper
• Na,K-ATPase and the role of α isoforms in behavior

  2007cited by this paper
• Synthesis, characterization and assessment of the cytotoxic properties of cis and trans-[Pd(L)(2)Cl(2)] complexes involving 6-benzylamino-9-isopropylpurine derivatives.

  2007cited by this paper
• Anticancer and antimicrobial metallopharmaceutical agents based on palladium, gold, and silver N-heterocyclic carbene complexes.

  2007cited by this paper
• Metal-based anticancer drugs: From a past anchored in platinum chemistry to a post-genomic future of diverse chemistry and biology

  2007cited by this paper
• The α1 subunit of the sodium pump could represent a novel target to combat non‐small cell lung cancers

  2007cited by this paper
• Curcumin and cyclopalladated complexes: a recipe for bifunctional biomaterials.

  2007cited by this paper
• Gold(III) compounds as anticancer drugs

  2007cited by this paper
• The activation of platinum(II) antiproliferative drugs in carbonate medium evaluated by means of a DNA-biosensor.

  2007cited by this paper
• Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions.

  2006cited by this paper
• The influence of potassium ion (K+) on digoxin-induced inhibition of porcine cerebral cortex Na+/K+-ATPase

  2006cited by this paper
• Prevention and recovery of (mu(3)-diethylentriamino)-chloro-palladium(II)-chloride induced inhibition of Na/K-ATPase by SH containing ligands--L-cysteine and glutathione.

  2006cited by this paper
• Platinum complexes as anticancer agents.

  2006cited by this paper
• Gold(III) dithiocarbamate derivatives for the treatment of cancer: solution chemistry, DNA binding, and hemolytic properties.

  2006cited by this paper
• Gold coordination complexes as anticancer agents.

  2006cited by this paper
• Interaction of some Pd(II) complexes with Na+/K+-ATPase: Inhibition, kinetics, prevention and recovery

  2006cited by this paper
• Organometallic chemistry, biology and medicine: ruthenium arene anticancer complexes.

  2005cited by this paper
• Heterocyclic complexes of ruthenium(III) induce apoptosis in colorectal carcinoma cells

  2005cited by this paper
• Controlling ligand substitution reactions of organometallic complexes: tuning cancer cell cytotoxicity.

  2005cited by this paper
• The effects of platinum-containing anti-cancer drugs on Na+, K+-ATPase activity in pig kidney and human renal proximal tubule epithelial cells

  2005cited by this paper
• Gold dithiocarbamate derivatives as potential antineoplastic agents: design, spectroscopic properties, and in vitro antitumor activity.

  2005cited by this paper
• Decavanadate effects in biological systems.

  2005cited by this paper
• Intrinsic and Acquired Forms of Resistance against the Anticancer Ruthenium Compound KP1019 [Indazolium trans-[tetrachlorobis(1H-indazole)ruthenate (III)] (FFC14A)

  2005cited by this paper
• The heterocyclic ruthenium(III) complex KP1019 (FFC14A) causes DNA damage and oxidative stress in colorectal tumor cells.

  2005cited by this paper
• Antitumoral properties of two new vanadyl(IV) complexes in osteoblasts in culture: role of apoptosis and oxidative stress

  2004cited by this paper
• A randomized controlled trial of fluorouracil plus leucovorin, irinotecan, and oxaliplatin combinations in patients with previously untreated metastatic colorectal cancer.

  2004cited by this paper
• Rate and Equilibrium Data for Substitution Reactions of [Pd(dien)Cl]+ with L-Cysteine and Glutathione in Aqueous Solution

  2004cited by this paper
• Synthesis, Crystal Structures and Anticancer Activity of the New Chiral Mono‐ and Dinuclear Palladium(II) Complexes derived from (S)‐(‐)‐(1‐phenylethylimino)benzylphenylketone

  2004cited by this paper
• Molecular mechanisms of platinum resistance: still searching for the Achilles' heel.

  2004cited by this paper
• The effect of cisplatin on renal ATPase activity in vivo and in vitro

  2004cited by this paper
• Up‐regulation of Na+,K+‐ATPase α3‐isoform and down‐regulation of the α1‐isoform in human colorectal cancer

  2004cited by this paper
• Pharmacokinetics of (glycolato-0,0′)-diammine platinum (II), a new platinum derivative, in comparison with cisplatin and carboplatin

  2004cited by this paper
• Influence of transition and heavy metal ions on ATP-ases activity in rat synaptic plasma membranes

  2004cited by this paper
• Chemopreventive effects of vanadium toward 1,2‐dimethylhydrazine‐induced genotoxicity and preneoplastic lesions in rat colon

  2004cited by this paper
• Cisplatin nephrotoxicity

  2004cited by this paper
• The chemistry and biochemistry of vanadium and the biological activities exerted by vanadium compounds.

  2004cited by this paper
• Analysis of the Na,K‐ATPase α‐ and β‐subunit expression profiles of bladder cancer using tissue microarrays

  2003cited by this paper
• Oxaliplatin-safety profile: neurotoxicity.

  2003cited by this paper
• A Phase I clinical and pharmacological study of cis-diamminedichloro(2-methylpyridine) platinum II (AMD473)

  2003cited by this paper
• Cisplatin: mode of cytotoxic action and molecular basis of resistance

  2003cited by this paper
• Repression of Na,K-ATPase beta1-subunit by the transcription factor snail in carcinoma.

  2003cited by this paper
• The odd couple: signal transduction and endocytosis

  2003cited by this paper
• Recent developments in the field of tumor-inhibiting metal complexes.

  2003cited by this paper
• Vanadium suppresses sister-chromatid exchange and DNA-protein crosslink formation and restores antioxidant status and hepatocellular architecture during 2-acetylaminofluorene-induced experimental rat hepatocarcinogenesis.

  2003cited by this paper
• Molecular Mechanisms of Na/K‐ATPase‐Mediated Signal Transduction

  2003cited by this paper
• Influence of sodium dodecyl sulfate on the kinetics of complex formation between [PdCl(dien)]+ and sulfur containing ligands l-cysteine and glutathione

  2003cited by this paper
• Gold(III) Compounds as New Family of Anticancer Drugs

  2003cited by this paper
• Functional Roles of the α Isoforms of the Na,K‐ATPase

  2003cited by this paper
• Structure and mechanism of Na,K-ATPase: functional sites and their interactions.

  2003cited by this paper
• Cellular and molecular pharmacology of oxaliplatin.

  2002cited by this paper
• Acquisition of resistance to cisplatin is accompanied by changes in the cellular pharmacology of copper.

  2002cited by this paper
• Kinetics and mechanism of the reaction of chelated Pd(II) complexes with thiols in acidic aqueous solution. Synthesis and crystal structure of [Pd(bpma)Cl]Cl·H2O (bpma = bis(2-pyridylmethyl)amine)

  2002cited by this paper
• Synthesis, crystal structure and initial biological evaluation of the new enantiomerically pure chiral palladium(II) complex trans-bis[endo-(1R)-1,7,7-trimethylbicyclo[2.2.1]-heptan-2-amino]palladium(II)dichloride.

  2002cited by this paper
• The sodium pump

  2002cited by this paper
• Mechanisms of cytotoxicity and antitumor activity of gold(I) phosphine complexes: the possible role of mitochondria

  2002cited by this paper
• Gold(III) complexes as a new family of cytotoxic and antitumor agents

  2002cited by this paper
• Vanadate inhibits the ATPase activity and DNA binding capability of bacterial MutS. A structural model for the vanadate-MutS interaction at the Walker A motif.

  2002cited by this paper
• Biochemistry of Na,K-ATPase.

  2002cited by this paper

• Effect of Fe3+ on Na,K-ATPase: Unexpected activation of ATP hydrolysis.

  2022cites this paper
• Selected polyoxopalladates as promising and selective antitumor drug candidates

  2021cites this paper
• The influence of oxo-bridged binuclear gold(III) complexes on Na/K-ATPase activity: a joint experimental and theoretical approach

  2017cites this paper