Differential polyamine sensitivity in inwardly rectifying Kir2 potassium channels

No abstract is available for this paper.

• Publication year

  2006

• Venue

  Journal of Physiology

• Publication date

  2006-03-01

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1113/jphysiol.2005.097741PMID 16373386PMCID PMC1796793
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• [Spermine].

  2020cited by this paper
• Mechanism of the Voltage Sensitivity of IRK1 Inward-rectifier K+ Channel Block by the Polyamine Spermine

  2005cited by this paper
• Evidence for Sequential Ion-binding Loci along the Inner Pore of the IRK1 Inward-rectifier K+ Channel

  2005cited by this paper
• Different intracellular polyamine concentrations underlie the difference in the inward rectifier K+ currents in atria and ventricles of the guinea‐pig heart

  2005cited by this paper
• Cytoplasmic domain structures of Kir2.1 and Kir3.1 show sites for modulating gating and rectification

  2005influential reference
• A ring of negative charges in the intracellular vestibule of Kir2.1 channel modulates K+ permeation.

  2005cited by this paper
• The inward rectifier current (IK1) controls cardiac excitability and is involved in arrhythmogenesis.

  2005cited by this paper
• Two Kir2.1 channel populations with different sensitivities to Mg2+ and polyamine block: a model for the cardiac strong inward rectifier K+ channel

  2005cited by this paper
• Two modes of polyamine block regulating the cardiac inward rectifier K+ current IK1 as revealed by the study of Kir2.1 channel

  2004influential reference
• Two modes of polyamine block regulating the cardiac inward rectifier K+ current IK1 as revealed by a study of the Kir2.1 channel expressed in a human cell line

  2004influential reference
• Unique Kir2.x Properties Determine Regional and Species Differences in the Cardiac Inward Rectifier K+ Current

  2004influential reference
• Barium block of Kir2 and human cardiac inward rectifier currents: evidence for subunit-heteromeric contribution to native currents.

  2003cited by this paper
• Molecular dissection of the inward rectifier potassium current (IK1) in rabbit cardiomyocytes: evidence for heteromeric co‐assembly of Kir2.1 and Kir2.2

  2003cited by this paper
• Mechanism of Rectification in Inward-rectifier K+ Channels

  2003cited by this paper
• Dominant-negative suppression of I(K1) in the mouse heart leads to altered cardiac excitability.

  2003cited by this paper
• IRK1 Inward Rectifier K+ Channels Exhibit No Intrinsic Rectification

  2002cited by this paper
• Spermine Block of th e Strong Inward Rectifier Potassium Channel Kir2.1: Dual Roles of Surface Charge Screening and Pore Block

  2002cited by this paper
• Spermine Block of the Strong Inward Rectifier Potassium Channel Kir2.1

  2002influential reference
• Differential distribution of Kir2.1 and Kir2.3 subunits in canine atrium and ventricle.

  2002cited by this paper
• Comparison of cloned Kir2 channels with native inward rectifier K+ channels from guinea‐pig cardiomyocytes

  2001cited by this paper
• Inward rectifiers in the heart: an update on I(K1).

  2001cited by this paper
• The consequences of disrupting cardiac inwardly rectifying K+ current (IK1) as revealed by the targeted deletion of the murine Kir2.1 and Kir2.2 genes

  2001cited by this paper
• Control of rectification and permeation by two distinct sites after the second transmembrane region in Kir2.1 K+ channel

  2001influential reference
• Mechanism of Irk1 Channel Block by Intracellular Polyamines

  2000influential reference
• Membrane Trafficking of the Cystic Fibrosis Gene Product, Cystic Fibrosis Transmembrane Conductance Regulator, Tagged with Green Fluorescent Protein in Madin-Darby Canine Kidney Cells*

  1998cited by this paper
• Time-dependent Outward Currents through the Inward Rectifier Potassium Channel IRK1

  1997cited by this paper
• [K+] dependence of polyamine-induced rectification in inward rectifier potassium channels (IRK1, Kir2.1)

  1996cited by this paper
• [K+] dependence of open-channel conductance in cloned inward rectifier potassium channels (IRK1, Kir2.1).

  1996cited by this paper
• Control of rectification and permeation by residues in two distinct domains in an inward rectifier K+ channel.

  1995influential reference
• The mechanism of inward rectification of potassium channels: "long-pore plugging" by cytoplasmic polyamines

  1995influential reference
• Strong voltage-dependent inward rectification of inward rectifier K+ channels is caused by intracellular spermine.

  1995cited by this paper
• C‐terminus determinants for Mg2+ and polyamine block of the inward rectifier K+ channel IRK1.

  1995cited by this paper
• Spermine and spermidine as gating molecules for inward rectifier K+ channels.

  1994cited by this paper
• Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification

  1994cited by this paper
• A single aspartate residue is involved in both intrinsic gating and blockage by Mg2+ of the inward rectifier, IRK1.

  1994cited by this paper
• The Mg[2+] block and intrinsic gating underlying inward rectification of the K[+] current in guinea-pig cardiac myocytes

  1990cited by this paper
• The Mg2+ block and intrinsic gating underlying inward rectification of the K+ current in guinea‐pig cardiac myocytes.

  1989cited by this paper
• Inward rectification in frog skeletal muscle fibres and its dependence on membrane potential and external potassium.

  1981cited by this paper
• Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

  1981influential reference
• Potassium current and the effect of cesium on this current during anomalous rectification of the egg cell membrane of a starfish

  1976cited by this paper
• Electrical properties of cardiac muscle attributable to inward going (anomalous) rectification

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• Ion channels of the human heart: A comprehensive four-chamber analysis.

  2026cites this paper
• The Kir2.1E299V mutation increases atrial fibrillation vulnerability while protecting the ventricles against arrhythmias in a mouse model of short QT syndrome type 3

  2024cites this paper
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  2024cites this paper
• Cardiac potassium inward rectifier Kir2: Review of structure, regulation, pharmacology, and arrhythmogenesis

  2021cites this paper
• --Differential contribution of the subthreshold operating currents IT, Ih and IKir to the resonance of thalamocortical neurons.

  2021cites this paper
• Procyanidin B1, a novel and specific inhibitor of Kv10.1 channel, suppresses the evolution of hepatoma.

  2020cites this paper
• Polyamines and potassium channels: A 25-year romance

  2018cites this paper
• T2N as a new tool for robust electrophysiological modeling demonstrated for mature and adult-born dentate granule cells

  2017cites this paper
• Molecular Basis of Functional Myocardial Potassium Channel Diversity.

  2016cites this paper
• Nonlinear conductance and heterogeneity of voltage-gated ion channels allow defining electrical surface domains in cell membranes

  2015cites this paper
• Mathematical Modeling of Electrical Activity and Exocytosis in Intestinal L-cells and Pancreatic Beta-cells

  2015cites this paper
• Inwardly rectifying Kir2.1 currents in human β-cells control electrical activity: characterisation and mathematical modelling.

  2015cites this paper
• Inward rectifier potassium current (IK1) and Kir2 composition of the zebrafish (Danio rerio) heart

  2015cites this paper
• Electrical coupling in ensembles of nonexcitable cells: modeling the spatial map of single cell potentials.

  2015cites this paper
• Regional variation of the inwardly rectifying potassium current in the canine heart and the contributions to differences in action potential repolarization.

  2015cites this paper
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• The interplay of seven subthreshold conductances controls the resting membrane potential and the oscillatory behavior of thalamocortical neurons.

  2014cites this paper
• Membrane potential bistability in nonexcitable cells as described by inward and outward voltage-gated ion channels.

  2014cites this paper
• 3 – Voltage-Regulated Potassium Channels

  2014cites this paper
• Inward-Rectifying Potassium (Kir) Channels Regulate Pacemaker Activity in Spinal Nociceptive Circuits during Early Life

  2013cites this paper
• 4 – Structural and Molecular Bases of Cardiac Inward Rectifier Potassium Channel Function

  2013cites this paper
• The function and molecular identity of inward rectifier channels in vestibular hair cells of the mouse inner ear.

  2012cites this paper
• Action potentials in primary osteoblasts and in the MG-63 osteoblast-like cell line

  2011cites this paper
• Functional consequences of Kir2.1/Kir2.2 subunit heteromerization

  2010influential citation
• Cardiac strong inward rectifier potassium channels.

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• Chronic heart failure and the substrate for atrial fibrillation.

  2009cites this paper
• Complex rectification of Müller cell Kir currents

  2008cites this paper
• A novel inwardly rectifying K+ channel, Kir2.5, is upregulated under chronic cold stress in fish cardiac myocytes

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• Differential regulation of action potential firing in adult murine thalamocortical neurons by Kv3.2, Kv1, and SK potassium and N‐type calcium channels

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• Low‐affinity spermine block mediating outward currents through Kir2.1 and Kir2.2 inward rectifier potassium channels

  2007cites this paper
• Heterogeneity of IK1 in the mouse heart.

  2007cites this paper
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• Heterogeneity of I K 1 in the mouse heart

  2007cites this paper
• Cloning and expression of cardiac Kir2.1 and Kir2.2 channels in thermally acclimated rainbow trout.

  2007cites this paper
• Physiologic function of I(K1) requires a combination of Kir2 isoforms.

  2007cites this paper
• Inhibition of cardiomyocyte automaticity by electrotonic application of inward rectifier current from Kir2.1 expressing cells

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• Cellular Physiology Cellular Physiology Cellular Physiology Cellular Physiology Cellular Physiology Functional Characterization of Inward Rectifier Potassium Ion Channel in Murine Fetal Ventricular Cardiomyocytes

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