Therapeutic agents in cancer are numerous and unique to different subtypes of malignancies. Given the different mechanisms of tumorigenesis including deleterious mutations, loss of important regulatory checkpoints, and proteins leading to uncontrolled cellular proliferation several means of targeted therapy exist. New agents in oncology including immune therapy, antiangiogenic drugs, targeted therapies, such as cyclin dependent kinase inhibitors help to target specific areas of the immune system and proliferation pathways to decrease tumor proliferation, growth, survival, and metastasis. This chapter serves to focus on the mechanisms of the new medications in cancer therapy that have changed the way we treat cancer.
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2017
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Biology, Medicine
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