A Haemophilus ducreyi CpxR deletion mutant is virulent in human volunteers.

No abstract is available for this paper.

• Publication year

  2011

• Venue

  Journal of Infectious Diseases

• Publication date

  2011-06-15

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1093/infdis/jir190PMID 21606544PMCID PMC3143453
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Bacterial stress responses.

  2011cited by this paper
• Activation of the CpxRA System by Deletion of cpxA Impairs the Ability of Haemophilus ducreyi To Infect Humans

  2010influential reference
• Characterization of the CpxRA Regulon in Haemophilus ducreyi

  2010influential reference
• The Cpx envelope stress response both facilitates and inhibits elaboration of the enteropathogenic Escherichia coli bundle-forming pilus

  2010cited by this paper
• Physiologically relevant small phosphodonors link metabolism to signal transduction.

  2010cited by this paper
• CpxRA Contributes to Xenorhabdus nematophila Virulence through Regulation of lrhA and Modulation of Insect Immunity

  2009cited by this paper
• Regulation of Expression of the Haemophilus ducreyi LspB and LspA2 Proteins by CpxR

  2009influential reference
• Experimental infection of human volunteers with Haemophilus ducreyi: fifteen years of clinical data and experience.

  2009cited by this paper
• Inactivation of the Haemophilus ducreyi luxS gene affects the virulence of this pathogen in human subjects.

  2009cited by this paper
• Bacterial adhesins in host-microbe interactions.

  2009cited by this paper
• Activation of the Cpx Envelope Stress Response Down-Regulates Expression of Several Locus of Enterocyte Effacement-Encoded Genes in Enteropathogenic Escherichia coli

  2008cited by this paper
• The enterobacterial common antigen-like gene cluster of Haemophilus ducreyi contributes to virulence in humans.

  2008cited by this paper
• Signal Integration by the Two-Component Signal Transduction Response Regulator CpxR

  2008cited by this paper
• Identification of Haemophilus ducreyi genes expressed during human infection.

  2008cited by this paper
• Extracytoplasmic-Stress-Responsive Pathways Modulate Type III Secretion in Yersinia pseudotuberculosis

  2007cited by this paper
• CpxR/OmpR Interplay Regulates Curli Gene Expression in Response to Osmolarity in Escherichia coli

  2005cited by this paper
• A Sensor of the Two-Component System CpxA Affects Expression of the Type III Secretion System through Posttranscriptional Processing of InvE

  2005cited by this paper
• Regulation of the pap epigenetic switch by CpxAR: phosphorylated CpxR inhibits transition to the phase ON state by competition with Lrp.

  2004cited by this paper
• Expression of the LspA1 and LspA2 Proteins by Haemophilus ducreyi Is Required for Virulence in Human Volunteers

  2004cited by this paper
• The LspB Protein Is Involved in the Secretion of the LspA1 and LspA2 Proteins by Haemophilus ducreyi

  2004influential reference
• Signal Detection and Target Gene Induction by the CpxRA Two-Component System

  2003cited by this paper
• Activation of hilA expression at low pH requires the signal sensor CpxA, but not the cognate response regulator CpxR, in Salmonella enterica serovar Typhimurium.

  2003cited by this paper
• Haemophilusducreyi Requires an Intact flp Gene Cluster for VirulenceinHumans

  2003cited by this paper
• Inhibition of Phagocytosis by Haemophilus ducreyi Requires Expression of the LspA1 and LspA2 Proteins

  2003cited by this paper
• Haemophilus ducreyi Requires an Intact flp Gene Cluster for Virulence in Humans

  2003cited by this paper
• Surface sensing and adhesion of Escherichia coli controlled by the Cpx-signaling pathway

  2002cited by this paper
• Haemophilus ducreyi: clinical features, epidemiology, and prospects for disease control.

  2002cited by this paper
• DsrA-Deficient Mutant of Haemophilus ducreyi Is Impaired in Its Ability To Infect Human Volunteers

  2001cited by this paper
• Serum Resistance in Haemophilus ducreyiRequires Outer Membrane Protein DsrA

  2000cited by this paper
• Expression of Peptidoglycan-Associated Lipoprotein Is Required for Virulence in the Human Model of Haemophilus ducreyi Infection

  2000cited by this paper
• Involvement of the Cpx signal transduction pathway of E. coli in biofilm formation.

  1999cited by this paper
• Identification of cpxR as a Positive Regulator Essential for Expression of the Shigella sonnei virF Gene

  1998cited by this paper
• Environmental Regulation of Salmonella typhi Invasion-Defective Mutants

  1998cited by this paper
• Haemophilus ducreyi Secretes a Filamentous Hemagglutinin-Like Protein

  1998cited by this paper
• Standardization of the experimental model of Haemophilus ducreyi infection in human subjects.

  1998cited by this paper
• The conserved 18,000-molecular-weight outer membrane protein of Haemophilus ducreyi has homology to PAL

  1996cited by this paper
• Involvement of cpxA, a sensor of a two-component regulatory system, in the pH-dependent regulation of expression of Shigella sonnei virF gene

  1995cited by this paper

• Dynamic response by commensal E. coli two-component system Cpx contributes to C. elegans development

  2026cites this paper
• Molecular pathogenesis of Haemophilus ducreyi infection in human volunteers

  2025cites this paper
• Interactions of the Skin Pathogen Haemophilus ducreyi With the Human Host

  2021cites this paper
• The CpxR regulates type VI secretion system 2 expression and facilitates the interbacterial competition activity and virulence of avian pathogenic Escherichia coli

  2019cites this paper
• Evaluation of CpxRA as a Therapeutic Target for Uropathogenic Escherichia coli Infections

  2018cites this paper
• Both MisR (CpxR) and MisS (CpxA) Are Required for Neisseria gonorrhoeae Infection in a Murine Model of Lower Genital Tract Infection

  2017cites this paper
• The exceptionally broad-based potential of active and passive vaccination targeting the conserved microbial surface polysaccharide PNAG

  2016cites this paper
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  2016cites this paper
• Phosphoethanolamine transferases in Haemophilus ducreyi modify lipid A and contribute to human defensin resistance

  2015cites this paper
• The CpxRA Two-Component System Is Essential for Citrobacter rodentium Virulence

  2015cites this paper
• Development and Validation of a High-Throughput Cell-Based Screen To Identify Activators of a Bacterial Two-Component Signal Transduction System

  2015cites this paper
• Haemophilus ducreyi: Chancroid

  2015cites this paper
• A (p)ppGpp-Null Mutant of Haemophilus ducreyi Is Partially Attenuated in Humans Due to Multiple Conflicting Phenotypes

  2014cites this paper
• Haemophilus ducreyi RpoE and CpxRA Appear To Play Distinct yet Complementary Roles in Regulation of Envelope-Related Functions

  2014cites this paper
• Activation of CpxRA in Haemophilus ducreyi Primarily Inhibits the Expression of Its Targets, Including Major Virulence Determinants

  2013influential citation
• The Haemophilus ducreyi Fis Protein Is Involved in Controlling Expression of the lspB-lspA2 Operon and Other Virulence Factors

  2013cites this paper
• The CpxAR Two-component System Regulates a Complex Envelope Stress Response in Gram-negative Bacteria

  2012cites this paper
• Carbon Storage Regulator A Contributes to the Virulence of Haemophilus ducreyi in Humans by Multiple Mechanisms

  2012cites this paper
• Sialylation of Lipooligosaccharides Is Dispensable for the Virulence of Haemophilus ducreyi in Humans

  2011cites this paper
• Expression of the Flp proteins by Haemophilus ducreyi is necessary for virulence in human volunteers

  2011cites this paper
• On the evolution of the sexually transmitted bacteria Haemophilus ducreyi and Klebsiella granulomatis

  2011cites this paper