S. Spinola

The etiology of exudative cutaneous ulcers in a yaws-endemic community prior to receipt of antimicrobials is similar to that found in communities after mass treatment with azithromycin
20260 citationsauthor #10
Molecular pathogenesis of Haemophilus ducreyi infection in human volunteers
20250 citationsauthor #1
The protein degradation system encoded by hslUV (ClpYQ) is dispensable for the virulence of Haemophilus ducreyi in human volunteers
20251 citationsauthor #6
Infections caused by Haemophilus ducreyi: one organism, two stories
20249 citationsauthor #2
A Haemophilus ducreyi strain lacking the yfeABCD iron transport system is virulent in human volunteers
20242 citationsauthor #6
Erratum for Brothwell et al., “Haemophilus ducreyi Infection Induces Oxidative Stress, Central Metabolic Changes, and a Mixed Pro- and Anti-Inflammatory Environment in the Human Host”
20230 citationsauthor #11
Formate production is dispensable for Haemophilus ducreyi virulence in human volunteers
20234 citationsauthor #9
Haemophilus ducreyi Infection Induces Oxidative Stress, Central Metabolic Changes, and a Mixed Pro- and Anti-inflammatory Environment in the Human Host
20226 citationsauthor #11
Ascorbic Acid Uptake and Utilization Encoded by ulaABCD Is Dispensable for the Virulence of Haemophilus ducreyi in Humans.
20226 citationsauthor #5
Two Streptococcus pyogenes emm types and several anaerobic bacterial species are associated with idiopathic cutaneous ulcers in children after community-based mass treatment with azithromycin
20228 citationsauthor #10
CpxA Phosphatase Inhibitor Activates CpxRA and Is a Potential Treatment for Uropathogenic Escherichia coli in a Murine Model of Infection
20229 citationsauthor #10
Genes Differentially Expressed by Haemophilus ducreyi during Anaerobic Growth Significantly Overlap Those Differentially Expressed during Experimental Infection of Human Volunteers
20224 citationsauthor #2
Interactions of the Skin Pathogen Haemophilus ducreyi With the Human Host
202114 citationsauthor #4
Streptococcus pyogenes Is Associated with Idiopathic Cutaneous Ulcers in Children on a Yaws-Endemic Island
202110 citationsauthor #12
Corrigendum to: Human Challenge Studies Are Unlikely to Accelerate Coronavirus Vaccine Licensure due to Ethical and Practical Issues
20210 citationsauthor #1
Human Challenge Studies Are Unlikely to Accelerate Coronavirus Vaccine Licensure Due to Ethical and Practical Issues
202010 citationsauthor #1
Human Challenge Studies With Wild-Type Severe Acute Respiratory Sydrome Coronavirus 2 Violate Longstanding Codes of Human Subjects Research
20204 citationsauthor #1
Determination of an Interaction Network between an Extracellular Bacterial Pathogen and the Human Host
201928 citationsauthor #10
A Class I Haemophilus ducreyi Strain Containing a Class II hgbA Allele Is Partially Attenuated in Humans: Implications for HgbA Vaccine Efficacy Trials
20195 citationsauthor #9
First-generation structure-activity relationship studies of 2,3,4,9-tetrahydro-1H-carbazol-1-amines as CpxA phosphatase inhibitors.
201915 citationsauthor #11
Evaluation of CpxRA as a Therapeutic Target for Uropathogenic Escherichia coli Infections
201825 citationsauthor #10
Multiple Class I and Class II Haemophilus ducreyi Strains Cause Cutaneous Ulcers in Children on an Endemic Island
201810 citationsauthor #9
Haemophilus ducreyi DNA is detectable on the skin of asymptomatic children, flies and fomites in villages of Papua New Guinea
201726 citationsauthor #13
Both MisR (CpxR) and MisS (CpxA) Are Required for Neisseria gonorrhoeae Infection in a Murine Model of Lower Genital Tract Infection
201720 citationsauthor #8
The Cutaneous Microbiota as a Determinant of Skin Barrier Function: Molecular Interactions and Therapeutic Opportunities
20162 citationsauthor #3
Host Polymorphisms in TLR9 and IL10 Are Associated With the Outcomes of Experimental Haemophilus ducreyi Infection in Human Volunteers.
20166 citationsauthor #5
Haemophilus ducreyi Seeks Alternative Carbon Sources and Adapts to Nutrient Stress and Anaerobiosis during Experimental Infection of Human Volunteers
201615 citationsauthor #9
Draft Whole-Genome Sequence of Haemophilus ducreyi Strain AUSPNG1, Isolated from a Cutaneous Ulcer of a Child from Papua New Guinea
20168 citationsauthor #5
The CpxRA System in Uropathogenic Escherichia coli Regulates Major Virulence Genes
20161 citationsauthor #7
Haemophilus ducreyi Cutaneous Ulcer Strains Diverged from Both Class I and Class II Genital Ulcer Strains: Implications for Epidemiological Studies
201614 citationsauthor #2
Phosphoethanolamine Transferase LptA in Haemophilus ducreyi Modifies Lipid A and Contributes to Human Defensin Resistance In Vitro
201524 citationsauthor #10
H. ducreyi PEA transferases do not confer resistance to human serum.
20150 citationsauthor #10
35000HPΔPEAT is fully virulent in vivo.
20150 citationsauthor #10
DksA and (p)ppGpp Have Unique and Overlapping Contributions to Haemophilus ducreyi Pathogenesis in Humans
201533 citationsauthor #11
The Human Skin Microbiome Associates with the Outcome of and Is Influenced by Bacterial Infection
2015111 citationsauthor #12
Development and Validation of a High-Throughput Cell-Based Screen To Identify Activators of a Bacterial Two-Component Signal Transduction System
201519 citationsauthor #9
Haemophilus ducreyi Cutaneous Ulcer Strains Are Nearly Identical to Class I Genital Ulcer Strains
201530 citationsauthor #12
A (p)ppGpp-Null Mutant of Haemophilus ducreyi Is Partially Attenuated in Humans Due to Multiple Conflicting Phenotypes
201414 citationsauthor #9
Haemophilus ducreyi RpoE and CpxRA Appear To Play Distinct yet Complementary Roles in Regulation of Envelope-Related Functions
20147 citationsauthor #7
Bacterial strains and plasmids used in this study.
201415 citationsauthor #10
Correcting imbalanced reads coverage in bacterial transcriptome sequencing with extreme deep coverage
20140 citationsauthor #4
Haemophilus ducreyi Hfq Contributes to Virulence Gene Regulation as Cells Enter Stationary Phase
201439 citationsauthor #14
Haemophilus ducreyi as a cause of skin ulcers.
20145 citationsauthor #1
Activation of CpxRA in Haemophilus ducreyi Primarily Inhibits the Expression of Its Targets, Including Major Virulence Determinants
201336 citationsauthor #7
The Haemophilus ducreyi Fis Protein Is Involved in Controlling Expression of the lspB-lspA2 Operon and Other Virulence Factors
20136 citationsauthor #5
Haemophilus ducreyi Infection Induces Activation of the NLRP3 Inflammasome in Nonpolarized but Not in Polarized Human Macrophages
201310 citationsauthor #4
nonpolarized but not in polarized human macrophages 3
20130 citationsauthor #4
Astabiotics: Antimicrobial Signal Transduction Activators
20130 citationsauthor #10
and Virulence of Haemophilus ducreyi in Humans
20120 citationsauthor #6
Permeases of the sap transporter are required for cathelicidin resistance and virulence of Haemophilus ducreyi in humans.
201227 citationsauthor #7
Carbon Storage Regulator A Contributes to the Virulence of Haemophilus ducreyi in Humans by Multiple Mechanisms
201217 citationsauthor #8
Haemophilus ducreyi-Induced Interleukin-10 Promotes a Mixed M1 and M2 Activation Program in Human Macrophages
201247 citationsauthor #3
Haemophilus ducreyi Lipooligosaccharides Induce Expression of the Immunosuppressive Enzyme Indoleamine 2,3-Dioxygenase via Type I Interferons and Tumor Necrosis Factor Alpha in Human Dendritic Cells
201131 citationsauthor #3
Sialylation of Lipooligosaccharides Is Dispensable for the Virulence of Haemophilus ducreyi in Humans
201112 citationsauthor #1
A Haemophilus ducreyi CpxR deletion mutant is virulent in human volunteers.
201121 citationsauthor #7
Haemophilus ducreyi SapA Contributes to Cathelicidin Resistance and Virulence in Humans
201043 citationsauthor #8
Activation of the CpxRA System by Deletion of cpxA Impairs the Ability of Haemophilus ducreyi To Infect Humans
201057 citationsauthor #1
Role played by CD4+FOXP3+ regulatory T Cells in suppression of host responses to Haemophilus ducreyi during experimental infection of human volunteers.
201015 citationsauthor #7
The role of CD4 + FOXP3 + regulatory T cells in suppression of host responses to Haemophilus ducreyi during experimental infection of human volunteers
20100 citationsauthor #8
Inactivation of the Haemophilus ducreyi luxS gene affects the virulence of this pathogen in human subjects.
200916 citationsauthor #7
Fatality despite appropriate treatment for babesiosis.
20090 citationsauthor #3
Experimental infection of human volunteers with Haemophilus ducreyi: fifteen years of clinical data and experience.
200982 citationsauthor #4
A fibrinogen-binding lipoprotein contributes to the virulence of Haemophilus ducreyi in humans.
200939 citationsauthor #7
Mechanism of human natural killer cell activation by Haemophilus ducreyi.
200924 citationsauthor #5
Haemophilus ducreyi Activates Human NK Cells through Interactions with Macrophages and Dendritic Cells
20090 citationsauthor #5
Evaluation of the repertoire of the TonB-dependent receptors of Haemophilus ducreyi for their role in virulence in humans.
200838 citationsauthor #7
The enterobacterial common antigen-like gene cluster of Haemophilus ducreyi contributes to virulence in humans.
200835 citationsauthor #7
Outer Membrane Protein DsrA Is the Major Fibronectin-Binding Determinant of Haemophilus ducreyi
200825 citationsauthor #6
Identification of Haemophilus ducreyi genes expressed during human infection.
200831 citationsauthor #6
Haemophilus ducreyi Partially Activates Human Myeloid Dendritic Cells
200734 citationsauthor #6
Dysregulated Immune Profiles for Skin and Dendritic Cells Are Associated with Increased Host Susceptibility to Haemophilus ducreyi Infection in Human Volunteers
200735 citationsauthor #12
Dysregulated Immune Proﬁles for Skin and Dendritic Cells Are Associated with Increased Host Susceptibility to Haemophilus ducreyi Infection in Human Volunteers (cid:1) †
20070 citationsauthor #12
Experimental infection with Haemophilus ducreyi in persons who are infected with HIV does not cause local or augment systemic viral replication.
200718 citationsauthor #11
A DltA Mutant of Haemophilus ducreyi Is Partially Attenuated in Its Ability To Cause Pustules in Human Volunteers
200628 citationsauthor #6
Localization of Haemophilus ducreyi in naturally acquired chancroidal ulcers.
200664 citationsauthor #4
Expression of OmpP2A and OmpP2B is not required for pustule formation by Haemophilus ducreyi in human volunteers.
200620 citationsauthor #6
Expression of Haemophilus ducreyi Collagen Binding Outer Membrane Protein NcaA Is Required for Virulence in Swine and Human Challenge Models of Chancroid
200642 citationsauthor #8
Trafficking Pathways and Characterization of CD4 and CD8 Cells Recruited to the Skin of Humans Experimentally Infected with Haemophilus ducreyi
200526 citationsauthor #5
The H8 antigen of pathogenic Neisseriae
20043 citationsauthor #7
Expression of the LspA1 and LspA2 Proteins by Haemophilus ducreyi Is Required for Virulence in Human Volunteers
200450 citationsauthor #7
Differences in Host Susceptibility to Disease Progression in the Human Challenge Model of Haemophilus ducreyi Infection
200345 citationsauthor #1
CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking.
2003237 citationsauthor #3
Haemophilus ducreyi Requires an Intact ﬂp Gene Cluster for Virulence in Humans
200345 citationsauthor #1
Haemophilusducreyi Requires an Intact flp Gene Cluster for VirulenceinHumans
200330 citationsauthor #1
Immunopathogenesis of Haemophilus ducreyi Infection (Chancroid)
200298 citationsauthor #1
Haemophilus ducreyi: clinical disease and pathogenesis
200222 citationsauthor #2
A Superoxide Dismutase C Mutant of Haemophilus ducreyi Is Virulent in Human Volunteers
200225 citationsauthor #7
Men Are More Susceptible Than Women to Pustule Formation in the Experimental Model of Haemophilus ducreyi Infection
200228 citationsauthor #4
Evolution of the Cutaneous Immune Response to Experimental Haemophilus ducreyi Infection and Its Relevance to HIV-1 Acquisition1 2
200235 citationsauthor #7
Haemophilus ducreyi: clinical features, epidemiology, and prospects for disease control.
200259 citationsauthor #3
Acquisition Infection and Its Relevance to HIV-1 ducreyi Haemophilus Response to Experimental Evolution of the Cutaneous Immune
20020 citationsauthor #7
Haemophilus ducreyi Lipooligosaccharide Mutant Defective in Expression of β-1,4-Glucosyltransferase Is Virulent in Humans
200112 citationsauthor #8
Transcription of Candidate Virulence Genes ofHaemophilus ducreyi during Infection of Human Volunteers
200129 citationsauthor #2
Haemophilus ducreyi Associates with Phagocytes, Collagen, and Fibrin and Remains Extracellular throughout Infection of Human Volunteers
200196 citationsauthor #4
Expression of Cytolethal Distending Toxin and Hemolysin Is Not Required for Pustule Formation by Haemophilus ducreyi in Human Volunteers
200163 citationsauthor #10
DsrA-Deficient Mutant of Haemophilus ducreyi Is Impaired in Its Ability To Infect Human Volunteers
200181 citationsauthor #7
Characterization of Haemophilus ducreyi-Specific T-Cell Lines from Lesions of Experimentally Infected Human Subjects
200125 citationsauthor #3
Localization of Haemophilus ducreyi at the Pustular Stage of Disease in the Human Model of Infection
200058 citationsauthor #2
Expression of Peptidoglycan-Associated Lipoprotein Is Required for Virulence in the Human Model of Haemophilus ducreyi Infection
200089 citationsauthor #7
A pilus-deficient mutant of Haemophilus ducreyi is virulent in the human model of experimental infection.
200031 citationsauthor #8

PROFILE

PAPERS

TIMELINE

COAUTHOR MAP

CONCEPT FOOTPRINT