Noninvasive determination of local cerebral metabolic rate of glucose in man.

No abstract is available for this paper.

• Publication year

  1980

• Venue

  American Journal of Physiology

• Publication date

  Unknown publication date

• Fields of study

  Medicine

• Identifiers
  DOI 10.1152/AJPENDO.1980.238.1.E69PMID 6965568
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The role of folate deficiency in electrophysiological neuropathy of experimental hepatoma of the rats

  1981cited by this paper
• Quantitation in Positron Emission Computed Tomography

  1980cited by this paper
• [Emission computed tomography].

  1980cited by this paper
• Quantitation in Positron Emission Computed Tomography: 1. Effect of Object Size

  1979cited by this paper
• METABOLIC TRAPPING AS A PRINCIPLE OF RADIO-PHARMACEUTICAL DESIGN: SOME FACTORS RESPONSIBLE FOR THE BIODISTRIBUTION OF 18F-2-DEOXY-2-FLUORO-D-GLUCOSE

  1979cited by this paper
• Tomographic measurement of local cerebral glucose metabolic rate in humans with (F‐18)2‐fluoro‐2‐deoxy‐D‐glucose: Validation of method

  1979cited by this paper
• The [18F]Fluorodeoxyglucose Method for the Measurement of Local Cerebral Glucose Utilization in Mane

  1979cited by this paper
• Quantitation in positron emission computed tomography: 2. Effects of inaccurate attenuation correction.

  1979cited by this paper
• Design Considerations in Positron Computed Tomography (PCT)

  1979cited by this paper
• Metabolic trapping as a principle of oradiopharmaceutical design: some factors resposible for the biodistribution of [18F] 2-deoxy-2-fluoro-D-glucose.

  1978cited by this paper
• Loss of radioactive 2-deoxy-D-glucose-6-phosphate from brains of conscious rats: implications for quantitative autoradiographic determination of regional glucose utilization.

  1978influential reference
• ECAT: a new computerized tomographic imaging system for positron-emitting radiopharmaceuticals.

  1978cited by this paper
• Local cerebral glucose utilization in the normal conscious macaque monkey

  1978cited by this paper
• Measurement of regional substrate utilization rates by emission tomography.

  1978cited by this paper
• Positron tomography: "in vivo" autoradiographic approach to measurement of cerebral hemodynamics and metabolism.

  1977cited by this paper
• THE [14C]DEOXYGLUCOSE METHOD FOR THE MEASUREMENT OF LOCAL CEREBRAL GLUCOSE UTILIZATION: THEORY, PROCEDURE, AND NORMAL VALUES IN THE CONSCIOUS AND ANESTHETIZED ALBINO RAT 1

  1977cited by this paper
• Radiopharmaceuticals XXVII. 18F-labeled 2-deoxy-2-fluoro-d-glucose as a radiopharmaceutical for measuring regional myocardial glucose metabolism in vivo: tissue distribution and imaging studies in animals.

  1977cited by this paper
• Emission computed tomography.

  1977cited by this paper
• In vivo measurement of brain glucose transport and metabolism employing glucose- -11C.

  1975cited by this paper
• ENZYMIC AND CEREBRAL METABOLIC EFFECTS OF 2‐DEOXY‐d‐GLUCOSE

  1973cited by this paper
• The effect of substitution at C-2 of D-glucose 6-phosphate on the rate of dehydrogenation by glucose 6-phosphate dehydrogenase (from yeast and from rat liver).

  1973cited by this paper
• The use of deoxyfluoro-D-glucopyranoses and related compounds in a study of yeast hexokinase specificity.

  1972cited by this paper
• The Effects of Ketamine on Cerebral Circulation and Metabolism in Man

  1972cited by this paper
• SPECIFICITY AND KINETIC PROPERTIES OF MONOSACCHARIDE UPTAKE INTO GUINEA PIG CEREBRAL CORTEX IN VITRO

  1971cited by this paper
• Brain uptake of radiolabeled amino acids, amines, and hexoses after arterial injection.

  1971cited by this paper
• Nonlinear Regression With Linear Constraints: An Extension of the Magnified Diagonal Method

  1970cited by this paper
• Synthesis of 2-deoxy-2-fluoro-D-glucose

  1969cited by this paper
• Effect of insulin on the synthesis of glycogen in cerebral cortical slices of alloxan diabetic rats.

  1968cited by this paper
• HEXOSE TRANSLOCATION ACROSS THE BLOOD‐BRAIN INTERFACE: CONFIGURATIONAL ASPECTS 1

  1968cited by this paper
• Effects of hypoxia and normocarbia on cerebral blood flow and metabolism in conscious man.

  1967cited by this paper
• [THE CARBOHYDRATE METABOLISM OF THE HUMAN BRAIN. I. STUDIES WITH SUBSTRATE-SPECIFIC ENZYMATIC METHODS IN NORMAL BRAIN CIRCULATION].

  1963cited by this paper
• Substrate specificity of brain hexokinase.

  1954cited by this paper
• Studies of the Cerebral Circulation and Metabolism in Congestive Heart Failure

  1953cited by this paper
• THE CEREBRAL BLOOD FLOW IN MALE SUBJECTS AS MEASURED BY THE NITROUS OXIDE TECHNIQUE. NORMAL VALUES FOR BLOOD FLOW, OXYGEN UTILIZATION, GLUCOSE UTILIZATION, AND PERIPHERAL RESISTANCE, WITH OBSERVATIONS ON THE EFFECT OF TILTING AND ANXIETY.

  1949cited by this paper

• Variability of the arterial input function in small-animal dynamic PET imaging.

  2026cites this paper
• Parametric imaging of dynamic long-axial-field-of-view PET scans: Technical challenges, statistical insights and clinical applications.

  2026cites this paper
• Brain aerobic glycolysis is stable during adulthood: Direct evidence from cross-brain blood sampling in 239 healthy adults

  2026cites this paper
• Kinetics of the amino acid uptake tracer O-(2-[18F]fluoroethyl)-L-tyrosine (FET) in human brain

  2025cites this paper
• Cerebral glucose delivery, transport and metabolism: Theory and modeling using four, three and two tissue compartments

  2025influential citation
• Positron emission tomography using 18F-fluorodeoxyglucose reveals digital perfusion deficits associated with continuous weight-bearing in healthy standing horses.

  2025cites this paper
• Dual-phase multiobjective Bayesian optimization method for estimating hepatocellular carcinoma dynamics parameters from PET/CT scans

  2025cites this paper
• Modeling of a population-based input function (PBIF) using the Feng model in dynamic ⁶⁸Ga-DOTATOC whole body PET/CT scans: feasibility of shortened imaging protocols on PET/CT Vision 600 system ®

  2025cites this paper
• Quantitative mapping of key glucose metabolic rates in the human brain using dynamic deuterium magnetic resonance spectroscopic imaging

  2025cites this paper
• Hepatocellular carcinoma 18F‐FDG PET/CT kinetic parameter estimation based on the advantage actor‐critic algorithm

  2025cites this paper
• A human brain map of mitochondrial respiratory capacity and diversity

  2025cites this paper
• A prior information-based multi-population multi-objective optimization for estimating 18F-FDG PET/CT pharmacokinetics of hepatocellular carcinoma

  2025cites this paper
• On the analysis of functional PET (fPET)-FDG: Baseline mischaracterization can introduce artifactual metabolic (de)activations

  2025influential citation
• Kinetic Modeling of Brain [18-F]FDG Positron Emission Tomography Time Activity Curves with Input Function Recovery (IR) Method

  2024influential citation
• Multi-Tracer Studies of Brain Oxygen and Glucose Metabolism Using a Time-of-Flight Positron Emission Tomography - Computed Tomography Scanner.

  2024cites this paper
• Seasonality in regional brain glucose metabolism

  2024cites this paper
• Enhancing Physiological Consistency in Dynamic PET/CT for Hepatocellular Carcinoma through Prior Information and NSGA-III

  2024cites this paper
• Simultaneous estimation of a model-derived input function for quantifying cerebral glucose metabolism with [18F]FDG PET

  2024cites this paper
• Quantitative Assessment in Dynamic PET/CT for Hepatocellular Carcinoma through Bayesian Prior information-based Actor-Critic algorithm

  2024cites this paper
• Patlak Slope versus Standardized Uptake Value Image Quality in an Oncologic PET/CT Population: A Prospective Cross-Sectional Study

  2024cites this paper
• A revised compartmental model for biokinetics and dosimetry of 2-[18F]FDG

  2023cites this paper
• Single time point quantitation of cerebral glucose metabolism by FDG-PET without arterial sampling

  2023influential citation
• Quantitation of dynamic total-body PET imaging: recent developments and future perspectives

  2023cites this paper
• Short-term PET-derived kinetic estimation for the diagnosis of hepatocellular carcinoma: a combination of the maximum-slope method and dual-input three-compartment model

  2023cites this paper
• Dynamic 18F-FDG-PET kinetic parameters for epileptogenic zone localization in drug-resistant epilepsy

  2023cites this paper
• Dual-tracer positron emission tomography/computed tomography as an imaging probe of de novo lipogenesis in preclinical models of hepatocellular carcinoma

  2022cites this paper
• Utility of PET Scans in the Diagnosis and Management of Gastrointestinal Tumors

  2022cites this paper
• Image Quantification for TSPO PET with a Novel Image-Derived Input Function Method

  2022cites this paper
• Simultaneous Denoising of Dynamic PET Images Based on Deep Image Prior

  2022influential citation
• First results on kinetic modelling and parametric imaging of dynamic 18F-FDG datasets from a long axial FOV PET scanner in oncological patients

  2022cites this paper
• Image-derived Input Function in brain [18F]FDG PET data: which alternatives to the carotid siphons?

  2022cites this paper
• Lower brain glucose metabolism in normal ageing is predominantly frontal and temporal: A systematic review and pooled effect size and activation likelihood estimates meta‐analyses

  2022influential citation
• Structural neuroimaging findings in bipolar disorders

  2021cites this paper
• Dynamic and metabolic quantification of nuclear medicine images in the PET/CT modality

  2021cites this paper
• Measuring Glycolytic Activity with Hyperpolarized [2H7, U-13C6] D-Glucose in the Naive Mouse Brain under Different Anesthetic Conditions

  2021influential citation
• Dynamic PET reconstruction using the kernel method with non-local means denoising

  2021cites this paper
• Working memory task induced neural activation: A simultaneous PET/fMRI study

  2021cites this paper
• A Model of Metabolic Supply-Demand Mismatch Leading to Secondary Brain Injury.

  2021cites this paper
• Kinetic metrics of 18F-FDG in normal human organs identified by systematic dynamic total-body positron emission tomography

  2021cites this paper
• Metabolic and Electrophysiological Effects of Fibroblast Growth Factor 19 in the Dorsal Vagal Complex

  2021cites this paper
• Radionuclide-Based Imaging of Breast Cancer: State of the Art

  2021cites this paper
• Brain perfusion imaging in neonates

  2021cites this paper
• Metabolic derangements are associated with impaired glucose delivery following traumatic brain injury

  2021cites this paper
• Hyperpolarized 13C-glucose magnetic resonance highlights reduced aerobic glycolysis in vivo in infiltrative glioblastoma

  2021cites this paper
• Content-based large-scale medical image retrieval

  2020cites this paper
• Machine learning derived input-function in a dynamic 18F-FDG PET study of mice

  2020cites this paper
• Image-based biomedical data modeling and parametric imaging

  2020cites this paper
• Tracer Kinetic Modelling

  2020cites this paper
• Compartmental Modeling in Emission Tomography

  2020cites this paper
• Compartment model-based nonlinear unmixing for kinetic analysis of dynamic PET images

  2020cites this paper
• Influence of phosphate concentration on amine, amide, and hydroxyl CEST contrast

  2020cites this paper
• Molecular imaging in biology and pharmacology

  2020cites this paper
• Kernel-based curve-fitting method with spatial regularization for generation of parametric images in dynamic PET

  2020influential citation
• Is There a Contribution of Structural Brain Phenotypes to the Variance in Resting Energy Expenditure before and after Weight Loss in Overweight Females?

  2019cites this paper
• Comparative assessment of linear least‐squares, nonlinear least‐squares, and Patlak graphical method for regional and local quantitative tracer kinetic modeling in cerebral dynamic 18F‐FDG PET

  2019cites this paper
• Essentials of Quantitative Imaging with PET

  2019cites this paper
• Brain Glucose Metabolism: Integration of Energetics with Function.

  2019cites this paper
• Adjusting gait step-by-step: Brain activation during split-belt treadmill walking

  2019cites this paper
• Computational approaches for parametric imaging of dynamic PET data

  2019cites this paper
• Peculiar cases of a “sleeping” brain in alert cancer patients

  2019cites this paper
• Finding sensitive parameters in internal dose calculations for radiopharmaceuticals commonly used in clinical nuclear medicine

  2018cites this paper
• Regional neuronal activity in patients with relapsing remitting multiple sclerosis

  2018cites this paper
• Fludeoxyglucose metabolism modeling: An overview

  2018cites this paper
• Affectionate Communication and Mental Wellness

  2018cites this paper
• An Introduction to Affectionate Communication

  2018cites this paper
• Decoding and Responding to Affectionate Messages

  2018cites this paper
• Affectionate Communication and Physical Health

  2018cites this paper
• Contribution of structural brain phenotypes to the variance in resting energy expenditure in healthy Caucasian subjects.

  2018cites this paper
• Preface

  2018cites this paper
• Communicating Affection in Various Relationships

  2018cites this paper
• Endnotes

  2018cites this paper
• The Dark Side of Affectionate Communication

  2018cites this paper
• References

  2018cites this paper
• Internal Dosimetry —A Review of Progress

  2018cites this paper
• Predicting Affectionate Behavior

  2018cites this paper
• Serotonin 5-HT1A receptor biased agonists induce different cerebral metabolic responses: A [18F]FDG PET study in conscious and anesthetized rats.

  2018cites this paper
• Practical Clinical Measurement of Radiotracer Concentration in Blood: Initial Device Concept and Feasibility Testing

  2018cites this paper
• Metabolic regional and network changes in Alzheimer's disease subtypes

  2018cites this paper
• Affectionate Communication in Close Relationships

  2018cites this paper
• Thinking about Affection

  2018cites this paper
• Trajectories of Brain Lactate and Re-visited Oxygen-Glucose Index Calculations Do Not Support Elevated Non-oxidative Metabolism of Glucose Across Childhood

  2018cites this paper
• Encoding and Measuring Affectionate Messages

  2018cites this paper
• Imaging Brain Metabolism in the Newborn

  2018cites this paper
• Index

  2018cites this paper
• Looking Back and Looking Ahead

  2018cites this paper
• Consensus statement on current and emerging methods for the diagnosis and evaluation of cerebrovascular disease

  2017cites this paper
• 18F-Fluorodeoxyglucose uptake on positron emission tomography/computed tomography is associated with metastasis and epithelial-mesenchymal transition in hepatocellular carcinoma

  2017cites this paper
• Differential effects of gaseous versus injectable anesthetics on changes in regional cerebral blood flow and metabolism induced by l‐DOPA in a rat model of Parkinson's disease

  2017cites this paper
• Longitudinal evaluation of myocardial glucose metabolism and contractile function in obese type 2 diabetic db/db mice using small-animal dynamic 18F-FDG PET and echocardiography

  2017cites this paper
• Performing Repeated Quantitative Small-Animal PET with an Arterial Input Function Is Routinely Feasible in Rats

  2017cites this paper
• Potential of Positron Emission Tomography for Studies of the Mechanisms of Development of Multiple Sclerosis (published data and authors’ results)

  2017cites this paper
• Adaptive Weighted Nonlinear Least Squares Method for Fluorodeoxyglucose Positron Emission Tomography Quantification

  2017influential citation
• Comparison of analytical methods of brain [18F]FDG-PET after severe traumatic brain injury.

  2017cites this paper
• Forward to the Past: The Case for Quantitative PET Imaging

  2017cites this paper
• Quantitative assessment of brain glucose metabolic rates using in vivo deuterium magnetic resonance spectroscopy

  2017cites this paper
• Cerebral metabolic rate of glucose quantification with the aortic image-derived input function and Patlak method: numerical and patient data evaluation

  2016cites this paper
• Functional Neuroimaging Techniques

  2016cites this paper
• Use of dynamic (18)F-fluorodeoxyglucose positron emission tomography to investigate choroid plexus function in Alzheimer's disease.

  2016cites this paper
• El envejecimiento y la ovariectomia causan una disminucion del consumo cerebral de glucosa in vivo en ratas Wistar

  2016cites this paper
• The Effects of Capillary Transit Time Heterogeneity (CTH) on the Cerebral Uptake of Glucose and Glucose Analogs: Application to FDG and Comparison to Oxygen Uptake

  2016cites this paper