The sugar kinase/heat shock protein 70/actin superfamily: implications of conserved structure for mechanism.

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Annual Review of Biophysics and Biomolecular Structure

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1146/ANNUREV.BB.25.060196.001033PMID 8800467
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• The actin fold

  1995cited by this paper
• How Potassium Affects the Activity of the Molecular Chaperone Hsc70

  1995cited by this paper
• The role of ATP in the functional cycle of the DnaK chaperone system.

  1995cited by this paper
• The ATP hydrolysis-dependent reaction cycle of the Escherichia coli Hsp70 system DnaK, DnaJ, and GrpE.

  1994cited by this paper
• Heat shock proteins and molecular chaperones: mediators of protein conformation and turnover in the cell.

  1994cited by this paper
• The chaperone function of DnaK requires the coupling of ATPase activity with substrate binding through residue E171.

  1994cited by this paper
• Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. I. Kinetic analyses of active site mutants.

  1994cited by this paper
• Domain motion in actin observed by fluorescence resonance energy transfer.

  1994cited by this paper
• A conserved loop in the ATPase domain of the DnaK chaperone is essential for stable binding of GrpE

  1994cited by this paper
• ATPase kinetics of recombinant bovine 70 kDa heat shock cognate protein and its amino-terminal ATPase domain.

  1994cited by this paper
• Kinetics of molecular chaperone action.

  1994cited by this paper
• Escherichia coli glycerol kinase: role of a tetramer interface in regulation by fructose 1,6-bisphosphate and phosphotransferase system regulatory protein IIIglc.

  1994cited by this paper
• Characterization of nucleotide-free uncoating ATPase and its binding to ATP, ADP, and ATP analogues.

  1994cited by this paper
• Structural basis of the 70-kilodalton heat shock cognate protein ATP hydrolytic activity. II. Structure of the active site with ADP or ATP bound to wild type and mutant ATPase fragment.

  1994cited by this paper
• Normal mode analysis of G-actin.

  1993cited by this paper
• Aspartyl residue 10 is essential for ATPase activity of rat hsc70.

  1993cited by this paper
• ATP-induced protein Hsp70 complex dissociation requires K+ but not ATP hydrolysis

  1993cited by this paper
• Structure of gelsolin segment 1-actin complex and the mechanism of filament severing

  1993cited by this paper
• Molecular chaperone functions of heat-shock proteins.

  1993cited by this paper
• Structure of the regulatory complex of Escherichia coli IIIGlc with glycerol kinase

  1993cited by this paper
• Refinement of the F-actin model against X-ray fiber diffraction data by the use of a directed mutation algorithm.

  1993cited by this paper
• Structure and mechanism of 70-kDa heat-shock-related proteins.

  1993cited by this paper
• Convergent evolution of similar enzymatic function on different protein folds: The hexokinase, ribokinase, and galactokinase families of sugar kinases

  1993cited by this paper
• Threonine 204 of the chaperone protein Hsc70 influences the structure of the active site, but is not essential for ATP hydrolysis.

  1993cited by this paper
• The structure of crystalline profilin-beta-actin.

  1993cited by this paper
• Structure and function of actin.

  1992cited by this paper
• The emergence of the chaperone machines.

  1992cited by this paper
• Regulation of Hsp70 function by a eukaryotic DnaJ homolog.

  1992cited by this paper
• The structure of the F-actin filament and the actin molecule.

  1992cited by this paper
• Protein folding in the cell

  1992cited by this paper
• An ATPase domain common to prokaryotic cell cycle proteins, sugar kinases, actin, and hsp70 heat shock proteins.

  1992cited by this paper
• Similarity of the three-dimensional structures of actin and the ATPase fragment of a 70-kDa heat shock cognate protein.

  1991cited by this paper
• Mechanism of the interaction of human platelet profilin with actin

  1991cited by this paper
• Interaction of hsp70 with unfolded proteins: effects of temperature and nucleotides on the kinetics of binding.

  1991cited by this paper
• Actin: protein structure and filament dynamics.

  1991cited by this paper
• The Escherichia coli DnaK chaperone, the 70-kDa heat shock protein eukaryotic equivalent, changes conformation upon ATP hydrolysis, thus triggering its dissociation from a bound target protein.

  1991cited by this paper
• A reversible conformational transition in muscle actin is caused by nucleotide exchange and uncovers cysteine in position 10.

  1991cited by this paper
• Secondary 18O isotope effects for hexokinase-catalyzed phosphoryl transfer from ATP.

  1991cited by this paper
• Nucleotide regulation of Escherichia coli glycerol kinase: initial-velocity and substrate binding studies.

  1990cited by this paper
• Actin-binding proteins.

  1990cited by this paper
• Atomic structure of the actin: DNase I complex

  1990cited by this paper
• Three-dimensional structure of the ATPase fragment of a 70K heat-shock cognate protein

  1990cited by this paper
• Effect of ATP on actin filament stiffness

  1990cited by this paper
• Atomic model of the actin filament

  1990cited by this paper
• Thiol and amino analogues as alternate substrates for glycerokinase from Candida mycoderma.

  1989cited by this paper
• Actin polymerization and ATP hydrolysis.

  1987cited by this paper
• The primary structure of the yeast hexokinase PII gene (HXK2) which is responsible for glucose repression.

  1985cited by this paper
• Allosteric regulation of glycerol kinase by enzyme IIIglc of the phosphotransferase system in Escherichia coli and Salmonella typhimurium

  1985cited by this paper
• Mechanisms of domain closure in proteins.

  1984cited by this paper
• Substrate synergism and the kinetic mechanism of yeast hexokinase.

  1982cited by this paper
• Structure of a complex between yeast hexokinase A and glucose. I. Structure determination and refinement at 3.5 A resolution.

  1980cited by this paper
• Structure of a complex between yeast hexokinase A and glucose. II. Detailed comparisons of conformation and active site configuration with the native hexokinase B monomer and dimer.

  1980cited by this paper
• Stereochemical course of phosphokinases. The use of adenosine [gamma-(S)-16O,17O,18O]triphosphate and the mechanistic consequences for the reactions catalyzed by glycerol kinase, hexokinase, pyruvate kinase, and acetate kinase.

  1979cited by this paper
• Yeast hexokinase in solution exhibits a large conformational change upon binding glucose or glucose 6-phosphate.

  1979cited by this paper
• Use of pH studies to elucidate the chemical mechanism of yeast hexokinase.

  1978cited by this paper
• Subunit dissociation in the allosteric regulation of glycerol kinase from Escherichia coli. 2. Physical evidence.

  1978cited by this paper
• A refined model of the sugar binding site of yeast hexokinase B.

  1978cited by this paper
• Subunit dissociation in the allosteric regulation of glycerol kinase from Escherichia coli. 1. Kinetic evidence.

  1978cited by this paper
• Yeast hexokinase PII. Conformational changes induced by substrates and substrate analogues.

  1978cited by this paper
• High resolution x-ray structure of yeast hexokinase, an allosteric protein exhibiting a non-symmetric arrangement of subunits.

  1976cited by this paper
• Yeast hexokinase: substrate-induced association--dissociation reactions in the binding of glucose to hexokinase P-II.

  1976cited by this paper
• Determination of the rate of hexokinase-glucose dissociation by the isotope-trapping method.

  1974cited by this paper
• Catalytic and allosteric properties of glycerol kinase from Escherichia coli.

  1973cited by this paper
• Dissociation of yeast hexokinase under the influence of substrates.

  1972cited by this paper
• Computer simulation studies with yeast hexokinase and additional evidence for the random Bi Bi mechanism.

  1971cited by this paper
• Composition and subunit structure of glycerol kinase from Escherichia coli.

  1971cited by this paper
• Induced fit in yeast hexokinase.

  1970cited by this paper
• Adenosine triphosphatase activity of yeast hexokinase and its relation to the mechanism of the hexokinase reaction.

  1965cited by this paper

• Recombinant expression and nucleotide hydrolysis activity of NTPDase 4 from Trichomonas vaginalis.

  2025cites this paper
• The Biology of tRNA t6A Modification and Hypermodifications-Biogenesis and Disease Relevance.

  2025cites this paper
• Levels of extracellular ATP in growth zones of Arabidopsis primary roots are changed by altered expression of apyrase enzymes

  2025cites this paper
• Crystal structure of glycerol kinase from Trypanosoma cruzi, a potential molecular target in Chagas disease.

  2024cites this paper
• Phylogenetic Challenges to the Evolutionary Origin of the Eukaryotic Cell Cycle

  2024cites this paper
• Structures of KEOPS bound to tRNA reveal functional roles of the kinase Bud32

  2024cites this paper
• The cluster model of energy transduction in biological systems

  2024cites this paper
• Structural and biochemical insights into the molecular mechanism of N-acetylglucosamine/N-Acetylmuramic acid kinase MurK from Clostridium acetobutylicum.

  2024cites this paper
• Structural Analysis of Plasmodium falciparum Hexokinase Provides Novel Information about Catalysis Due to a Plasmodium-Specific Insertion

  2023cites this paper
• Indications for a genetic basis for big bacteria and description of the giant cable bacterium Candidatus Electrothrix gigas sp. nov.

  2023cites this paper
• Exploring the Role of the Plant Actin Cytoskeleton: From Signaling to Cellular Functions

  2023cites this paper
• Bound nucleotide can control the dynamic architecture of monomeric actin

  2022cites this paper
• Fusarium graminearum Ste3 G-Protein Coupled Receptor: A Mediator of Hyphal Chemotropism and Pathogenesis

  2022cites this paper
• Identification of resistance gene analogs of the NBS-LRR family through transcriptome probing and in silico prediction of the expressome of Dalbergia sissoo under dieback disease stress

  2022cites this paper
• Structural basis for coupled ATP-driven electron transfer in the double-cubane cluster protein

  2022cites this paper
• TXH11106: A Third-Generation MreB Inhibitor with Enhanced Activity against a Broad Range of Gram-Negative Bacterial Pathogens

  2022cites this paper
• The structural and functional workings of KEOPS

  2021cites this paper
• FGGY Carbohydrate Kinase Domain Containing is Expressed and Alternatively Spiced in Skeletal Muscle and Attenuates MAP Kinase and Akt Signaling.

  2021cites this paper
• Recent Advances Clarifying the Structure and Function of Plant Apyrases (Nucleoside Triphosphate Diphosphohydrolases)

  2021cites this paper
• The Role of Heat Shock Protein 70 kDa in Asthma

  2021cites this paper
• Computational Insights into the Deleterious Impacts of Missense Variants on N-Acetyl-d-glucosamine Kinase Structure and Function

  2021cites this paper
• FGGY Carbohydrate Kinase Domain Containing is Induced During Skeletal Muscle Atrophy and Modulates Map Kinase and AKT Signaling

  2021cites this paper
• Novel Antibacterial Targets in Protein Biogenesis Pathways

  2021cites this paper
• Genome organization: Tag it, move it, place it.

  2020cites this paper
• The complexity and diversity of the actin cytoskeleton of trypanosomatids.

  2020cites this paper
• Affinity shift of ATP upon glycerol binding to a glycerol kinase from the hyperthermophilic archaeon Thermococcus kodakarensis KOD1.

  2020cites this paper
• Identification, Sequencing and Stability Evaluation of Eight Reference Genes in Saffron (Crocus sativus L.)

  2020cites this paper
• N-Acetyl-d-Glucosamine Kinase Interacts with NudC and Lis1 in Dynein Motor Complex and Promotes Cell Migration

  2020cites this paper
• Kinetic and substrate complex characterization of RamA, a corrinoid protein reductive activase from Methanosarcina barkeri.

  2020cites this paper
• Crystal structure of Porphyromonas gingivalis phosphotransacetylase

  2019cites this paper
• Heat shock-induced chaperoning by Hsp70 is enabled in-cell

  2019cites this paper
• Fusion of the Genes WWTR1 and FOSB in Pseudomyogenic Hemangioendothelioma

  2019cites this paper
• Characterization of the phosphotransacetylase-acetate kinase pathway for ATP production in Porphyromonas gingivalis

  2019cites this paper
• Carbohydrate Kinases: A Conserved Mechanism Across Differing Folds

  2019influential citation
• Inverse docking based screening and identification of protein targets for Cassiarin alkaloids against Plasmodium falciparum

  2018cites this paper
• Nuclear actin: ancient clue to evolution in eukaryotes?

  2018cites this paper
• Evidence of link between quorum sensing and sugar metabolism in Escherichia coli revealed via cocrystal structures of LsrK and HPr

  2018cites this paper
• Yeast KEOPS complex regulates telomere length independently of its t6A modification function.

  2018cites this paper
• Structures and kinetics for plant nucleoside triphosphate diphosphohydrolases support a domain motion catalytic mechanism

  2017cites this paper
• ISTANBUL TECHNICAL UNIVERSITY GRADUATE SCHOOL OF SCIENCE ENGINEERING AND TECHNOLOGY MOLECULAR DYNAMICS SIMULATION ANALYSIS OF HIS226 MUTATION ON THE DYNAMICS OF THE ATPASE DOMAIN OF DNAK M.Sc. THESIS

  2017cites this paper
• Developing transcriptional profiles in Orbicella franksi exposed to copper: Characterizing responses associated with a spectrum of laboratory-controlled environmental conditions.

  2017cites this paper
• Evolution of polymer formation within the actin superfamily

  2017cites this paper
• Structural and functional mapping of Rtg2p determinants involved in retrograde signaling and aging of Saccharomyces cerevisiae

  2017cites this paper
• Bioconversion of anhydrosugars: Emerging concepts and strategies

  2016cites this paper
• N-Acetyl-D-Glucosamine Kinase Interacts with Dynein-Lis1-NudE1 Complex and Regulates Cell Division

  2016cites this paper
• In Silico Molecular Modeling and Docking Studies on Novel Mutants (E229V, H225P and D230C) of the Nucleotide-Binding Domain of Homo sapiens Hsp70

  2016cites this paper
• Epistasis effects of multiple ancestral-consensus amino acid substitutions on the thermal stability of glycerol kinase from Cellulomonas sp. NT3060.

  2016cites this paper
• Substrate independent ATPase activity may complicate high throughput screening.

  2016cites this paper
• Crystal Structures of Putative Sugar Kinases from Synechococcus Elongatus PCC 7942 and Arabidopsis Thaliana

  2016cites this paper
• The Hsp70 Family of Heat Shock Proteins in Tumorigenesis: From Molecular Mechanisms to Therapeutic Opportunities

  2015cites this paper
• Molecular cloning, characterization and phylogenetic analysis of an actin gene from the marine mollusk Rapana venosa (class Gastropoda)

  2015cites this paper
• Role of Ectoapyrases in Nodulation

  2015cites this paper
• KAEA (SUDPRO), a member of the ubiquitous KEOPS/EKC protein complex, regulates the arginine catabolic pathway and the expression of several other genes in Aspergillus nidulans.

  2015cites this paper
• Molecular dynamics simulation and docking studies on novel mutants (T11V, T12P and D364S) of the nucleotide-binding domain of human heat shock 70 kDa protein

  2015cites this paper
• Stress Response Pathways in Cancer

  2015influential citation
• Producing Glucose-6-Phosphate from Cellulosic Biomass: Structural Insights into Levoglucosan Bioconversion

  2015cites this paper
• Structures of substrate- and nucleotide-bound propionate kinase from Salmonella typhimurium: substrate specificity and phosphate-transfer mechanism.

  2015cites this paper
• Producing Glucose 6-Phosphate from Cellulosic Biomass

  2015cites this paper
• The Role of Active Site Residues in ATP Binding and Catalysis in the Methanosarcina thermophila Acetate Kinase

  2015cites this paper
• Determination of essentiality and regulatory function of staphylococcal YeaZ in branched-chain amino acid biosynthesis

  2015cites this paper
• Comparative analysis of salinity-induced proteomic changes in cotton (Gossypium hirsutum L.).

  2015cites this paper
• N-Acetyl-D-Glucosamine Kinase Is a Component of Nuclear Speckles and Paraspeckles

  2015cites this paper
• N-acetyl-D-glucosamine kinase interacts with dynein light-chain roadblock type 1 at Golgi outposts in neuronal dendritic branch points

  2015cites this paper
• Structural and functional analysis of fucose-processing enzymes from Streptococcus pneumoniae.

  2014cites this paper
• The extended reductive acetyl-CoA pathway: ATPases in metal cluster maturation and reductive activation

  2014influential citation
• ATP-induced electron transfer by redox-selective partner recognition

  2014cites this paper
• The Non-Canonical Effect of N-Acetyl-D-Glucosamine Kinase on the Formation of Neuronal Dendrites

  2014cites this paper
• Insights into the binding specificity and catalytic mechanism of N-acetylhexosamine 1-phosphate kinases through multiple reaction complexes.

  2014cites this paper
• Kinetic regulation of a corrinoid‐reducing metallo‐ATPase by its substrates

  2014influential citation
• Different Trends in the Evolution of Heat Shock Genes System

  2014cites this paper
• Heat Shock Proteins and Whole Body Adaptation to Extreme Environments

  2014cites this paper
• A putative role of the Sup35p C-terminal domain in the cytoskeleton organization during yeast mitosis.

  2014cites this paper
• Crystal structures of acetate kinases from the eukaryotic pathogens Entamoeba histolytica and Cryptococcus neoformans.

  2013influential citation
• Targeting acetate kinase: inhibitors as potential bacteriostatics.

  2013cites this paper
• The role of glycerol kinase in plasmodium falciparum

  2013influential citation
• Carbohydrate Kinase (RhaK)-Dependent ABC Transport of Rhamnose in Rhizobium leguminosarum Demonstrates Genetic Separation of Kinase and Transport Activities

  2013influential citation
• Conformational Itinerary of Pseudomonas aeruginosa 1,6-Anhydro-N-acetylmuramic Acid Kinase during Its Catalytic Cycle*

  2013cites this paper
• Mechanistic features of Salmonella typhimurium propionate kinase (TdcD): insights from kinetic and crystallographic studies.

  2013cites this paper
• O-Carbamoyltransferase TobZ

  2013cites this paper
• Structural Basis for the Reaction Mechanism of S-Carbamoylation of HypE by HypF in the Maturation of [NiFe]-Hydrogenases*

  2012cites this paper
• The O-carbamoyltransferase TobZ catalyzes an ancient enzymatic reaction.

  2012cites this paper
• Redox-dependent complex formation by an ATP-dependent activator of the corrinoid/iron-sulfur protein

  2012influential citation
• Die O‐Carbamoyltransferase TobZ katalysiert eine enzymatische Reaktion frühen Ursprungs

  2012cites this paper
• Novel Pyrophosphate-Forming Acetate Kinase from the Protist Entamoeba histolytica

  2012cites this paper
• On the ATP-dependent activation of the radical enzyme (R)-2-hydroxyisocaproyl-CoA dehydratase.

  2012cites this paper
• Structural and enzymatic characterisation of nucleoside triphosphate diphosphohydrolases from Trifolium repens and Dolichos biflorus

  2012cites this paper
• Structure and Function of Human Xylulokinase, an Enzyme with Important Roles in Carbohydrate Metabolism*

  2012cites this paper
• The influences of conformational dynamics on T cell receptor specificity and cross-reactivity

  2012cites this paper
• Structural basis for profilin-mediated actin nucleotide exchange.

  2012cites this paper
• Use of a repetitive seeding protocol to obtain diffraction-quality crystals of a putative human D-xylulokinase.

  2012cites this paper
• The Phylogenomic Roots of Modern Biochemistry: Origins of Proteins, Cofactors and Protein Biosynthesis

  2012cites this paper
• Direct detection of the acetate-forming activity of the enzyme acetate kinase.

  2011cites this paper
• Structural Analysis of the Essential Resuscitation Promoting Factor YeaZ Suggests a Mechanism of Nucleotide Regulation through Dimer Reorganization

  2011influential citation
• Functional Analysis of the Cytoskeleton Protein MreB from Chlamydophila pneumoniae

  2011cites this paper
• Mutations in the nucleotide binding pocket of MreB can alter cell curvature and polar morphology in Caulobacter

  2011cites this paper
• The FGGY Carbohydrate Kinase Family: Insights into the Evolution of Functional Specificities

  2011cites this paper
• Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones

  2011influential citation
• Enzymatic Activity of the Soybean Ecto-Apyrase GS52 Is Essential for Stimulation of Nodulation1[W][OA]

  2011cites this paper
• Structure of 2-oxo-3-deoxygalactonate kinase from Klebsiella pneumoniae.

  2011cites this paper
• The GDA1_CD39 superfamily: NTPDases with diverse functions

  2011cites this paper