An unresolved problem in physics is how the thermodynamic arrow of time arises from an underlying time reversible dynamics. We contribute to this issue by developing a measure of time-symmetry breaking, and by using the work fluctuation relations, we determine the time asymmetry of recent single molecule RNA unfolding experiments. We define time asymmetry as the Jensen-Shannon divergence between trajectory probability distributions of an experiment and its time-reversed conjugate. Among other interesting properties, the length of time's arrow bounds the average dissipation and determines the difficulty of accurately estimating free energy differences in nonequilibrium experiments.
ABSTRACT
PUBLICATION RECORD
- Publication year
2008
- Venue
Physical Review Letters
- Publication date
2008-08-29
- Fields of study
Medicine, Physics
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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