An examination of how Rab GTPases and molecular chaperones influence plasma membrane expression of chemokine receptor dimers

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Unknown venue

• Publication date

  2013-11-22

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Identification of endoplasmic reticulum export motifs for G protein-coupled receptors.

  2013cited by this paper
• A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations

  2013cited by this paper
• Anterograde Trafficking of CXCR4 and CCR2 Receptors in a Prostate Cancer Cell Line

  2013influential reference
• CCL2/CCR2 Chemokine Signaling Coordinates Survival and Motility of Breast Cancer Cells through Smad3 Protein- and p42/44 Mitogen-activated Protein Kinase (MAPK)-dependent Mechanisms*

  2012cited by this paper
• Essential role of the adaptor protein Nck1 in Jurkat T cell activation and function

  2012cited by this paper
• HIV: cell binding and entry.

  2012cited by this paper
• Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway.

  2012cited by this paper
• Epigenetic control of CCR5 transcript levels in immune cells and modulation by small molecules inhibitors

  2012cited by this paper
• Rab11 regulates exocytosis of recycling vesicles at the plasma membrane

  2012cited by this paper
• Oligomerization of G-Protein-Coupled Receptors

  2012cited by this paper
• HIV-1 antiretroviral drug therapy.

  2012cited by this paper
• Dopamine Receptor-Interacting Protein 78 Acts as a Molecular Chaperone for CCR5 Chemokine Receptor Signaling Complex Organization

  2012influential reference
• Protein aggregates in Huntington's disease.

  2012cited by this paper
• Role of Rab GTPases in membrane traffic and cell physiology.

  2011influential reference
• Focal adhesion kinase and its signaling pathways in cell migration and angiogenesis.

  2011cited by this paper
• Chemokines in health and disease.

  2011influential reference
• G Protein Activation by Serotonin Type 4 Receptor Dimers

  2011influential reference
• Dependence on different Rab GTPases for the trafficking of CXCR4 and CCR5 homo or heterodimers between the endoplasmic reticulum and plasma membrane in Jurkat cells.

  2011influential reference
• Trans‐activation between 7TM domains: implication in heterodimeric GABAB receptor activation

  2011influential reference
• Proteomic-Based Identification of CD4-Interacting Proteins in Human Primary Macrophages

  2011cited by this paper
• Scaffold Proteins: Hubs for Controlling the Flow of Cellular Information

  2011cited by this paper
• HIV-1 envelope glycoprotein biosynthesis, trafficking, and incorporation.

  2011influential reference
• Ccr5 regulates inflammatory gene expression in response to encephalomyocarditis virus infection.

  2011cited by this paper
• Dimers and beyond: The functional puzzles of class C GPCRs.

  2011influential reference
• Abnormal calcium homeostasis and protein folding stress at the ER

  2011cited by this paper
• G protein-coupled receptors: novel targets for drug discovery in cancer

  2010cited by this paper
• Therapeutic antibodies directed at G protein-coupled receptors

  2010cited by this paper
• Na+/H+ Exchanger Regulatory Factor-1 Is Involved in Chemokine Receptor Homodimer CCR5 Internalization and Signal Transduction but Does Not Affect CXCR4 Homodimer or CXCR4-CCR5 Heterodimer*

  2010influential reference
• CXCL12 (SDF-1)/CXCR4 Pathway in Cancer

  2010cited by this paper
• Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain*♦

  2010cited by this paper
• From the Cover: Rescue of defective G protein-coupled receptor function in vivo by intermolecular cooperation

  2010influential reference
• Animal models of amyloid‐β‐related pathologies in Alzheimer’s disease

  2010cited by this paper
• Chaperones contribute to G protein coupled receptor oligomerization, but do not participate in assembly of the G protein with the receptor signaling complex

  2010influential reference
• Escorts take the lead molecular chaperones as therapeutic targets.

  2010cited by this paper
• Putting G protein–coupled receptor-mediated activation of phospholipase C in the limelight

  2010cited by this paper
• Monocyte Chemoattractant Protein-1 (MCP-1): An Overview

  2009cited by this paper
• Inhibition of chemokine receptor expression on uveal melanomas by CXCR4 siRNA and its effect on uveal melanoma liver metastases.

  2009cited by this paper
• Cancer metastasis scrutinized

  2009cited by this paper
• Host and Viral Factors Influencing the Pathogenesis of HIV-Associated Neurocognitive Disorders

  2009cited by this paper
• Calreticulin enhances B2 bradykinin receptor maturation and heterodimerization.

  2009cited by this paper
• Focal adhesion kinase and cancer.

  2009cited by this paper
• Hetero-oligomerization of CCR2, CCR5, and CXCR4 and the Protean Effects of “Selective” Antagonists*

  2009cited by this paper
• A Golgi-on-a-chip for glycan synthesis.

  2009cited by this paper
• CD4-CCR5 interaction in intracellular compartments contributes to receptor expression at the cell surface.

  2009cited by this paper
• Bimolecular fluorescence complementation: visualization of molecular interactions in living cells.

  2008cited by this paper
• Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer

  2008cited by this paper
• Heterotrimeric G protein activation by G-protein-coupled receptors

  2008cited by this paper
• One step at a time: endoplasmic reticulum-associated degradation

  2008cited by this paper
• Conformational cross-talk between alpha2A-adrenergic and mu-opioid receptors controls cell signaling.

  2008cited by this paper
• Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer

  2008cited by this paper
• A small-molecule compound targeting CCR5 and CXCR3 prevents airway hyperresponsiveness and inflammation

  2008cited by this paper
• Antiretroviral treatment of adult HIV infection: 2008 recommendations of the International AIDS Society-USA panel.

  2008cited by this paper
• Large Scale Screening for Novel Rab Effectors Reveals Unexpected Broad Rab Binding Specificity*S

  2008cited by this paper
• An escort for GPCRs: implications for regulation of receptor density at the cell surface.

  2008cited by this paper
• Protein Aggregation in the Brain: The Molecular Basis for Alzheimer’s and Parkinson’s Diseases

  2008cited by this paper
• GPCRTree: online hierarchical classification of GPCR function

  2008cited by this paper
• Structural views of glycoprotein-fate determination in cells.

  2007influential reference
• CCL2 as an important mediator of prostate cancer growth in vivo through the regulation of macrophage infiltration.

  2007cited by this paper
• CCL2/CCR2 pathway mediates recruitment of myeloid suppressor cells to cancers.

  2007cited by this paper
• Enzymes catalyzing protein folding and their cellular functions.

  2007cited by this paper
• Legionella pneumophila proteins that regulate Rab1 membrane cycling

  2007cited by this paper
• Dopamine receptor-interacting protein 78 acts as a molecular chaperone for Ggamma subunits before assembly with Gbeta.

  2007cited by this paper
• Researchers tackle metastasis, cancer's last frontier.

  2007cited by this paper
• Signalling complexes associated with adenylyl cyclase II are assembled during their biosynthesis.

  2007cited by this paper
• Hepatotoxicity Observed in Clinical Trials of Aplaviroc (GW873140)

  2007cited by this paper
• CCR2 expression correlates with prostate cancer progression

  2007influential reference
• Regulation of CXCR4 signaling.

  2007cited by this paper
• D1 and D2 Dopamine Receptor Expression Is Regulated by Direct Interaction with the Chaperone Protein Calnexin*

  2007cited by this paper
• Allosteric Transinhibition by Specific Antagonists in CCR2/CXCR4 Heterodimers*

  2007cited by this paper
• Impact of GPCRs in clinical medicine: monogenic diseases, genetic variants and drug targets.

  2007cited by this paper
• Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease

  2007cited by this paper
• Methods for the detection and analysis of protein–protein interactions

  2007cited by this paper
• Trafficking of preassembled opioid mu-delta heterooligomer-Gz signaling complexes to the plasma membrane: coregulation by agonists.

  2007cited by this paper
• G‐protein‐coupled receptor expression, function, and signaling in macrophages

  2007cited by this paper
• G protein coupled receptor structure and activation.

  2007cited by this paper
• Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques.

  2007cited by this paper
• Rab GTPases at a glance

  2007cited by this paper
• In and out of the ER: protein folding, quality control, degradation, and related human diseases.

  2007influential reference
• Functional specialization of β-arrestin interactions revealed by proteomic analysis

  2007cited by this paper
• How many drug targets are there?

  2006cited by this paper
• Differential Regulation of the Cell-Surface Targeting and Function of β- and α1-Adrenergic Receptors by Rab1 GTPase in Cardiac Myocytes

  2006influential reference
• Interaction between the CCR5 chemokine receptors and microbial HSP70

  2006influential reference
• Mechanism of Assembly of G Protein βγ Subunits by Protein Kinase CK2-phosphorylated Phosducin-like Protein and the Cytosolic Chaperonin Complex*

  2006cited by this paper
• GS Activation Is Time-limiting in Initiating Receptor-mediated Signaling*

  2006cited by this paper
• Dimerization of CXCR4 in living malignant cells: control of cell migration by a synthetic peptide that reduces homologous CXCR4 interactions

  2006cited by this paper
• Interactions between GABA-B1 receptors and Kir 3 inwardly rectifying potassium channels.

  2006cited by this paper
• GRKs and arrestins: regulators of migration and inflammation

  2006cited by this paper
• Are G Protein‐Coupled Receptor Heterodimers of Physiological Relevance?—Focus on Melatonin Receptors

  2006cited by this paper
• Seven Transmembrane Receptor Core Signaling Complexes Are Assembled Prior to Plasma Membrane Trafficking*

  2006influential reference
• CCL2 Regulates Angiogenesis via Activation of Ets-1 Transcription Factor1

  2006cited by this paper
• The ER-Golgi intermediate compartment (ERGIC): in search of its identity and function

  2006cited by this paper
• The Legionella pneumophila effector protein DrrA is a Rab1 guanine nucleotide-exchange factor

  2006cited by this paper
• Simultaneous activation of the delta opioid receptor (deltaOR)/sensory neuron-specific receptor-4 (SNSR-4) hetero-oligomer by the mixed bivalent agonist bovine adrenal medulla peptide 22 activates SNSR-4 but inhibits deltaOR signaling.

  2006influential reference
• Monocyte chemotactic protein‐1 (MCP‐1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion

  2006cited by this paper
• G-Protein Signaling Triggered by R5 Human Immunodeficiency Virus Type 1 Increases Virus Replication Efficiency in Primary T Lymphocytes

  2005cited by this paper
• Emerging role of RAB GTPases in cancer and human disease.

  2005influential reference
• A heterodimer-selective agonist shows in vivo relevance of G protein-coupled receptor dimers.

  2005cited by this paper
• Subcellular distribution of GABAB receptor homo-and heterodimers

  2005cited by this paper
• Bioluminescence Resonance Energy Transfer Reveals Ligand-induced Conformational Changes in CXCR4 Homo- and Heterodimers*

  2005cited by this paper
• Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells.

  2005cited by this paper

• No citing papers are available for this paper.