Mu‐opioid receptor knockout mice show diminished food‐anticipatory activity

No abstract is available for this paper.

• Publication year

  2004

• Venue

  European Journal of Neuroscience

• Publication date

  2004-09-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1111/j.1460-9568.2004.03581.xPMID 15355329
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Hyperdopaminergic mutant mice have higher "wanting" but not "liking" for sweet rewards.

  2004cited by this paper
• A region of mesial prefrontal cortex tracks monetarily rewarding outcomes: characterization with rapid event-related fMRI

  2003cited by this paper
• Selective psychostimulant sensitization by food restriction: differential changes in accumbens shell and core dopamine

  2003influential reference
• Food- and light-entrained circadian rhythms in rats with hypocretin-2-saporin ablations of the lateral hypothalamus.

  2003cited by this paper
• Differential effects of morphine and cocaine on locomotor activity and sensitization in mu-opioid receptor knockout mice.

  2003cited by this paper
• Anticipation is differently expressed in rats (Rattus norvegicus) and domestic cats (Felis silvestris catus) in the same Pavlovian conditioning paradigm.

  2003cited by this paper
• Standard housed rats are more sensitive to rewards than enriched housed rats as reflected by their anticipatory behaviour.

  2003cited by this paper
• Subsecond dopamine release promotes cocaine seeking

  2003cited by this paper
• Increased dopamine D2 receptor binding and enhanced apomorphine-induced locomotor activity in mu-opioid receptor knockout mice.

  2003cited by this paper
• Parsing reward.

  2003cited by this paper
• Induction of c-fos in nucleus accumbens in naive male Balb/c mice after wheel running.

  2003cited by this paper
• Access to enriched housing is rewarding to rats as reflected by their anticipatory behaviour

  2003cited by this paper
• Research report Motivational views of reinforcement: implications for understanding the behavioral functions of nucleus accumbens dopamine

  2002cited by this paper
• Selective reward deficit in mice lacking beta-endorphin and enkephalin.

  2002cited by this paper
• Selective Reward Deficit in Mice Lacking β-Endorphin and Enkephalin

  2002cited by this paper
• Available online at www.sciencedirect.com R

  2002cited by this paper
• Dopamine release in human ventral striatum and expectation of reward.

  2002cited by this paper
• Endogenous opioids in dopaminergic cell body regions modulate amphetamine-induced increases in extracellular dopamine levels in the terminal regions.

  2002influential reference
• Effects of acute “binge” cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotropin‐releasing hormone receptor mRNA levels in the striatum and hypothalamic–pituitary–adrenal axis of mu‐opioid receptor knockout mice

  2002cited by this paper
• Dissociation of reward anticipation and outcome with event-related fMRI

  2001cited by this paper
• Region specific increase of dopamine receptor D1/D2 mRNA expression in the brain of mu-opioid receptor knockout mice.

  2001cited by this paper
• Anticipation of Increasing Monetary Reward Selectively Recruits Nucleus Accumbens

  2001cited by this paper
• Region specific increase of dopamine receptor D1/D2 mRNA expression in the brain of μ-opioid receptor knockout mice

  2001cited by this paper
• A concept of welfare based on reward evaluating mechanisms in the brain: anticipatory behaviour as an indicator for the state of reward systems.

  2001influential reference
• Restricted‐feeding‐induced anticipatory activity rhythm is associated with a phase‐shift of the expression of mPer1 and mPer2 mRNA in the cerebral cortex and hippocampus but not in the suprachiasmatic nucleus of mice

  2001cited by this paper
• Multiple reward signals in the brain

  2000cited by this paper
• Defeat followed by individual housing results in long-term impaired reward- and cognition-related behaviours in rats.

  2000cited by this paper
• Differential responsiveness of dopamine transmission to food-stimuli in nucleus accumbens shell/core compartments.

  1999cited by this paper
• Dissociation in Effects of Lesions of the Nucleus Accumbens Core and Shell on Appetitive Pavlovian Approach Behavior and the Potentiation of Conditioned Reinforcement and Locomotor Activity byd-Amphetamine

  1999cited by this paper
• Retention of heroin and morphine–6β–glucuronide analgesia in a new line of mice lacking exon 1 of MOR–1

  1999influential reference
• Expression of melanocortin-5 receptor in secretory epithelia supports a functional role in exocrine and endocrine glands.

  1998cited by this paper
• Parallel strain-dependent effect of amphetamine on locomotor activity and dopamine release in the nucleus accumbens: an in vivo study in mice.

  1997influential reference
• Quantitative autoradiographic mapping of mu-, delta- and kappa-opioid receptors in knockout mice lacking the mu-opioid receptor gene.

  1997cited by this paper
• Anticipation and entrainment to feeding time in intact and SCN-ablated C57BL/6j mice.

  1997cited by this paper
• Quantitative autoradiographic mapping of μ-, δ- and κ-opioid receptors in knockout mice lacking the μ-opioid receptor gene

  1997cited by this paper
• Food reward: brain substrates of wanting and liking.

  1996cited by this paper
• Stress, depression and the mesolimbic dopamine system

  1996cited by this paper
• Computational and entrainment models of circadian food-anticipatory activity: evidence from non-24-hr feeding schedules.

  1995cited by this paper
• Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications.

  1995cited by this paper
• Circadian food-anticipatory activity: formal models and physiological mechanisms.

  1994cited by this paper
• Differential involvement of ventral tegmental mu, delta and kappa opioid receptors in modulation of basal mesolimbic dopamine release: in vivo microdialysis studies.

  1993cited by this paper
• Morphine-dopamine interaction: ventral tegmental morphine increases nucleus accumbens dopamine release.

  1991influential reference
• Feeding cycles entrain circadian rhythms of locomotor activity in CS mice but not in C57BL/6J mice.

  1989cited by this paper
• Dopamine and preparatory behavior: II. A neurochemical analysis.

  1989influential reference
• The notion of ethological need, models of motivation and animal-welfare

  1988cited by this paper
• Opposite effects of mu and kappa opiate agonists on dopamine release in the nucleus accumbens and in the dorsal caudate of freely moving rats.

  1988cited by this paper
• Emotion and Cognition.

  1987cited by this paper
• Stress-induced facilitation of acoustic startle after d-amphetamine administration.

  1982cited by this paper
• Effects of chemical stimulation of the mesolimbic dopamine system upon locomotor activity.

  1976cited by this paper

• Disrupted intersubject variability architecture in structural and functional brain connectomes in major depressive disorder

  2025cites this paper
• Chronic administration of methocinnamox, a mu-opioid receptor antagonist, reduces hedonic response without impacting motivation in mice

  2025cites this paper
• Endogenous opioid receptors and the feast or famine of maladaptive feeding

  2025cites this paper
• Exploring the role of beta‐endorphin in activity‐based anorexia in mice

  2025cites this paper
• Reward processing in schizophrenia and its relation to Mu opioid receptor availability and negative symptoms: A [11C]-carfentanil PET and fMRI study

  2023cites this paper
• Mu-opioid receptor knockout on Foxp2-expressing neurons reduces aversion-resistant alcohol drinking

  2023cites this paper
• Inhibition of POMC neurons in mice undergoing activity-based anorexia selectively blunts food anticipatory activity without affecting bodyweight or food intake.

  2022cites this paper
• The opioid system in depression

  2022cites this paper
• Endogenous opioids contribute to the feeling of pain relief in humans

  2021cites this paper
• Activity-based anorexia animal model: a review of the main neurobiological findings

  2021cites this paper
• β‐endorphin differentially contributes to food anticipatory activity in male and female mice undergoing activity‐based anorexia

  2021influential citation
• Potential for Kappa-Opioid Receptor Agonists to Engineer Nonaddictive Analgesics: A Narrative Review.

  2020cites this paper
• Anticipatory Behavior for a Mealworm Reward in Laying Hens Is Reduced by Opioid Receptor Antagonism but Not Standard Feed Intake

  2020cites this paper
• Deletion of mu opioid receptors reduces palatable solution intake in a mouse model of binge eating

  2020cites this paper
• Investigation of the genetic components of maternal infanticide in Sus Scrofa

  2019cites this paper
• Endogenous opioid modulation of food intake and body weight: Implications for opioid influences upon motivation and addiction.

  2019cites this paper
• Enkephalins and ACTH in the mammalian nervous system.

  2019cites this paper
• The Dynamic Nature of the POMC Neuron Landscape, and the Impact of POMC Peptides and Body Composition States in Motivated Feeding

  2019cites this paper
• Tyrosine Hydroxylase Inhibition in Substantia Nigra Decreases Movement Frequency

  2018cites this paper
• Methods for Investigating the Motivation of Mice to Explore and Access Food Rewards.

  2018cites this paper
• Influence of enclosure condition and visitor numbers on behaviour of captive Malayan tapir

  2018cites this paper
• Influence of Enclosure Conditions and Visitors on the Behavior of Captive Malayan Tapir (Tapirus indicus): Implications for Ex Situ Management and Conservation

  2018cites this paper
• The Mysterious Food-Entrainable Oscillator: Insights from Mutant and Engineered Mouse Models

  2018cites this paper
• The Running Wheel Enhances Food Anticipatory Activity: An Exploratory Study

  2016cites this paper
• Responses to drugs of abuse and non-drug rewards in leptin deficient ob/ob mice

  2016cites this paper
• Interacting Neural Processes of Feeding, Hyperactivity, Stress, Reward, and the Utility of the Activity-Based Anorexia Model of Anorexia Nervosa.

  2016cites this paper
• New Technologies for Elucidating Opioid Receptor Function.

  2016cites this paper
• The Use of Animal Models to Decipher Physiological and Neurobiological Alterations of Anorexia Nervosa Patients

  2015cites this paper
• Endogenous opioids and feeding behavior: A decade of further progress (2004-2014). A Festschrift to Dr. Abba Kastin.

  2015cites this paper
• On the Neurobiology of Physical Activity in Mice and Human : In search of Eating Disorders Determinants

  2014cites this paper
• Intermittent Feeding Schedules—Behavioural Consequences and Potential Clinical Significance

  2014cites this paper
• Attenuation of cocaine and heroin seeking by μ-opioid receptor antagonism

  2013cites this paper
• Decreased consumption of sweet fluids in mu opioid receptor knockout mice: a microstructural analysis of licking behavior

  2013influential citation
• Overlapping striatal sites mediate scopolamine-induced feeding suppression and mu-opioid-mediated hyperphagia in the rat

  2013cites this paper
• Chapter 155 – Opioids

  2013cites this paper
• PKCγ participates in food entrainment by regulating BMAL1

  2012cites this paper
• NPY receptor subtype specification for behavioral adaptive strategies during limited food access

  2012cites this paper
• Acute and chronic suppression of the central ghrelin signaling system reveals a role in food anticipatory activity.

  2011cites this paper
• Genetic Studies of Opioid System Function in Mice

  2011cites this paper
• Neurobiology driving hyperactivity in activity-based anorexia.

  2011cites this paper
• Hedonic and motivational roles of opioids in food reward: implications for overeating disorders.

  2010cites this paper
• Regulation by endogenous dopamine of the expression of the clock protein, PERIOD2, in the forebrain of the male Wistar rat

  2010cites this paper
• Opioids: Culprits for Overconsumption of Palatable Foods?

  2010cites this paper
• Bidirectional interactions between the circadian and reward systems: is restricted food access a unique zeitgeber?

  2009cites this paper
• Mice lacking the G protein gamma3-subunit show resistance to opioids and diet induced obesity.

  2009cites this paper
• Convergent, not serial, striatal and pallidal circuits regulate opioid-induced food intake.

  2009cites this paper
• Interspecies genetics of eating disorder traits

  2009cites this paper
• Orally administered H-Dmt-Tic-Lys-NH-CH2-Ph (MZ-2), a potent mu/delta-opioid receptor antagonist, regulates obese-related factors in mice.

  2009cites this paper
• Reward processing by the opioid system in the brain.

  2009cites this paper
• From taste hedonics to motivational drive: central μ-opioid receptors and binge-eating behaviour.

  2009cites this paper
• Opioid reward 'liking' and 'wanting' in the nucleus accumbens.

  2008cites this paper
• Increased adiposity on normal diet, but decreased susceptibility to diet-induced obesity in mu-opioid receptor-deficient mice.

  2008cites this paper
• Leptin's effect on hyperactivity: potential downstream effector mechanisms.

  2008cites this paper
• Opioid-Dependent Anticipatory Negative Contrast and Binge-Like Eating in Rats with Limited Access to Highly Preferred Food

  2008cites this paper
• Gene expression profiling in porcine maternal infanticide: A model for puerperal psychosis

  2008cites this paper
• Dopaminergic and brain‐derived neurotrophic factor signalling in inbred mice exposed to a restricted feeding schedule

  2008cites this paper
• Behavioral genetic contributions to the study of addiction-related amphetamine effects.

  2008cites this paper
• Assessment of positive emotions in animals to improve their welfare.

  2007cites this paper
• Cellular learning theory: theoretical comment on Cole and McNally (2007).

  2007cites this paper
• Opioids for hedonic experience and dopamine to get ready for it

  2007cites this paper
• [N-allyl-Dmt1]-endomorphins are micro-opioid receptor antagonists lacking inverse agonist properties.

  2007cites this paper
• Mu opioid receptor knockout mice in the Morris Water Maze: a learning or motivation deficit?

  2007cites this paper
• [N-Allyl-Dmt1]-Endomorphins Are μ-Opioid Receptor Antagonists Lacking Inverse Agonist Properties

  2007cites this paper
• To eat or not to eat; regulation by the melanocortin system.

  2006cites this paper
• Evolved to satisfy our immediate needs: self-control and the rewarding properties of food.

  2006cites this paper
• AgRP(83-132) and SHU9119 differently affect activity-based anorexia.

  2006cites this paper
• Anticipatory behaviour and stereotypical behaviour in farmed mink (Mustela vison) in the presence, absence and after the removal of swimming water

  2006cites this paper
• Orexins and Opioids in Feeding Behavior

  2006cites this paper
• Methamphetamine‐induced behavioral sensitization in mice: alterations in mu‐opioid receptor

  2006cites this paper
• Differential involvement of endogenous opioids in sucrose consumption and food reinforcement.

  2006cites this paper
• "Feeding time" for the brain: a matter of clocks.

  2006cites this paper
• Differential Regulation of the Consummatory, Motivational and Anticipatory Aspects of Feeding Behavior by Dopaminergic and Opioidergic Drugs

  2006cites this paper
• Sexual receptivity is reduced in the female mu-opioid receptor knockout mouse

  2005cites this paper
• Resistance to Diet-Induced Obesity in μ-Opioid Receptor–Deficient Mice: Evidence for a “Thrifty Gene”

  2005cites this paper
• Short communication Automated home cage observations as a tool to measure the effects of wheel running on cage floor locomotion

  2005cites this paper
• Endogenous opiates and behavior: 2004.

  2005cites this paper