Differential Effects of Methylmercury on γ-Aminobutyric Acid Type A Receptor Currents in Rat Cerebellar Granule and Cerebral Cortical Neurons in Culture

No abstract is available for this paper.

• Publication year

  2007

• Venue

  Journal of Pharmacology and Experimental Therapeutics

• Publication date

  2007-10-31

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1124/jpet.107.123976PMID 17977981
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• GABAA receptor subtypes expressed in cerebellar granule cells: a developmental study.

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  2003cited by this paper
• Relationship between Availability of NMDA Receptor Subunits and Their Expression at the Synapse

  2002influential reference
• Effects of Methylmercury on Human Neuronal L-Type Calcium Channels Transiently Expressed in Human Embryonic Kidney Cells (HEK-293)

  2002cited by this paper
• Slow phases of GABAA receptor desensitization: structural determinants and possible relevance for synaptic function

  2002cited by this paper
• Inositol 1,4,5-triphosphate receptor-sensitive Ca(2+) release, store-operated Ca(2+) entry, and cAMP responsive element binding protein phosphorylation in developing cortical cells following exposure to polychlorinated biphenyls.

  2001cited by this paper
• Effects of GABAA receptor partial agonists in primary cultures of cerebellar granule neurons and cerebral cortical neurons reflect different receptor subunit compositions

  2001cited by this paper
• Identification of an Amino Acid Defining the Distinct Properties of Murine β1 and β3 Subunit‐Containing GABAA Receptors

  2000influential reference
• Methylmercury alters glutamate transport in astrocytes.

  2000cited by this paper
• Identification of an amino acid defining the distinct properties of murine beta1 and beta3 subunit-containing GABA(A) receptors.

  2000cited by this paper
• Inhibition of GABAA receptor (GABAR) currents by arachidonic acid in HEK 293 cells stably transfected with α1β2γ2 GABAR subunits

  2000cited by this paper
• Comparative effects of methylmercury on parallel-fiber and climbing-fiber responses of rat cerebellar slices.

  1999cited by this paper
• Residues in transmembrane domains I and II determine gamma-aminobutyric acid type AA receptor subtype-selective antagonism by furosemide.

  1999cited by this paper
• Excitotoxic cell death dependent on inhibitory receptor activation.

  1999influential reference
• Loreclezole and La3+ differentiate cerebellar granule cell GABA(A) receptor subtypes.

  1999cited by this paper
• Elevations of intracellular Ca2+ as a probable contributor to decreased viability in cerebellar granule cells following acute exposure to methylmercury.

  1998cited by this paper
• Calcium released from intracellular stores inhibits GABAA-mediated currents in ganglion cells of the turtle retina.

  1998influential reference
• Developmental expression of cerebellar GABAA-receptor subunit mRNAs. Nature versus nurture.

  1998cited by this paper
• Cognitive performance of children prenatally exposed to "safe" levels of methylmercury.

  1998cited by this paper
• The Role of an α Subtype M2-M3 His in Regulating Inhibition of GABAA Receptor Current by Zinc and Other Divalent Cations

  1998cited by this paper
• Cerebellar gamma-aminobutyric acid type A receptors: pharmacological subtypes revealed by mutant mouse lines.

  1997cited by this paper
• Sites of alcohol and volatile anaesthetic action on GABAA and glycine receptors

  1997cited by this paper
• Contrasting actions of lanthanum on different recombinant gamma-aminobutyric acid receptor isoforms expressed in L929 fibroblasts.

  1997influential reference
• The Role of (cid:97) 1 and (cid:97) 6 Subtype Amino-Terminal Domains in Allosteric Regulation of (cid:103) -Aminobutyric Acid a Receptors

  1997cited by this paper
• The role of alpha1 and alpha6 subtype amino-terminal domains in allosteric regulation of gamma-aminobutyric acida receptors.

  1997cited by this paper
• Action of methylmercury on GABA(A) receptor-mediated inhibitory synaptic transmission is primarily responsible for its early stimulatory effects on hippocampal CA1 excitatory synaptic transmission.

  1997cited by this paper
• The interaction of the general anesthetic etomidate with the gamma-aminobutyric acid type A receptor is influenced by a single amino acid.

  1997cited by this paper
• The cerebellum: a model system for studying GABAA receptor diversity.

  1996cited by this paper
• Development of a tonic form of synaptic inhibition in rat cerebellar granule cells resulting from persistent activation of GABAA receptors.

  1996cited by this paper
• The effects of raising intracellular calcium on synaptic GABAA receptor-channels.

  1996cited by this paper
• Properties of putative cerebellar gamma-aminobutyric acid A receptor isoforms.

  1996cited by this paper
• Relative densities of synaptic and extrasynaptic GABAA receptors on cerebellar granule cells as determined by a quantitative immunogold method

  1995cited by this paper
• Methylmercury acts at multiple sites to block hippocampal synaptic transmission.

  1995cited by this paper
• Neonatal Rat Cerebellar Granule and Purkinje Neurons in Culture Express Different GABAA Receptors

  1995cited by this paper
• Selective antagonist for the cerebellar granule cell-specific gamma-aminobutyric acid type A receptor.

  1995cited by this paper
• GABAA/benzodiazepine receptor α6 subunit mRNA in granule cells of the cerebellar cortex and cochlear nuclei: Expression in developing and mutant mice

  1994cited by this paper
• Methylmercury‐Induced Elevations in Intrasynaptosomal Zinc Concentrations: An 19F‐NMR Study

  1994cited by this paper
• Assembly of GABAA receptor subunits: role of the delta subunit

  1994influential reference
• GABAA Receptor Subtypes Expressed in Cerebellar Granule Cells: A Developmental Study

  1994cited by this paper
• Mechanisms of methylmercury‐induced neurotoxicity

  1994cited by this paper
• The effect of intracellular Ca2+ on GABA-activated currents in cerebellar granule cells in culture

  1994cited by this paper
• Disruption by methylmercury of membrane excitability and synaptic transmission of CA1 neurons in hippocampal slices of the rat.

  1993cited by this paper
• Currents Activated by GABA and their Modulation by Zn2+ in Cerebellar Granule Cells in Culture

  1993cited by this paper
• Methylmercury alters intrasynaptosomal concentrations of endogenous polyvalent cations.

  1993cited by this paper
• Methylmercury increases intracellular concentrations of Ca++ and heavy metals in NG108-15 cells.

  1993cited by this paper
• GABAA receptors: ligand-gated Cl- ion channels modulated by multiple drug-binding sites.

  1992cited by this paper
• Function and pharmacology of multiple GABAA receptor subunits

  1992cited by this paper
• The distribution of 13 GABAA receptor subunit mRNAs in the rat brain. II. Olfactory bulb and cerebellum

  1992cited by this paper
• The distribution of thirteen GABAA receptor subunit mRNAs in the rat brain. III. Embryonic and postnatal development

  1992cited by this paper
• Modulation of decay kinetics and frequency of GABAA receptor-mediated spontaneous inhibitory postsynaptic currents in hippocampal neurons.

  1992cited by this paper
• Mercury modulation of GABA-activated chloride channels and non-specific cation channels in rat dorsal root ganglion neurons.

  1991cited by this paper
• Cerebellar GABAA receptor selective for a behavioural alcohol antagonist

  1990cited by this paper
• Functional and molecular distinction between recombinant rat GABAA receptor subtypes by Zn2+.

  1990influential reference
• The role of depolarization in the survival and differentiation of cerebellar granule cells in culture

  1987cited by this paper
• Intracellular calcium ions decrease the affinity of the GABA receptor

  1986cited by this paper
• Neurotoxic effects of mercury--a review.

  1977cited by this paper
• Methylmercury poisoning in Iraq.

  1973cited by this paper
• An Algorithm for Least-Squares Estimation of Nonlinear Parameters

  1963cited by this paper
• A METHOD FOR THE SOLUTION OF CERTAIN NON – LINEAR PROBLEMS IN LEAST SQUARES

  1944cited by this paper

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  2017cites this paper
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  2012cites this paper
• Methylmercury: a potential environmental risk factor contributing to epileptogenesis.

  2012cites this paper
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  2012cites this paper
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  2011cites this paper
• Methylmercury disrupts the balance between phosphorylated and non-phosphorylated cofilin in primary cultures of mice cerebellar granule cells. A proteomic study.

  2010cites this paper
• Altered GABAA receptor expression as biomarker of mercury toxicity in embryonic neurogenesis

  2009cites this paper
• Methylmercury neurotoxicity is associated with inhibition of the antioxidant enzyme glutathione peroxidase.

  2009cites this paper
• Three dimensional morphometric analyses of axon terminals early changes induced by methylmercury intoxication in the adult cat striate cortex.

  2008cites this paper