Yeast Cbk1 and Mob2 activate daughter-specific genetic programs to induce asymmetric cell fates.

No abstract is available for this paper.

• Publication year

  2001

• Venue

  Cell

• Publication date

  2001-12-14

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/S0092-8674(01)00596-7PMID 11747810
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Order of function of the budding-yeast mitotic exit-network proteins Tem1, Cdc15, Mob1, Dbf2, and Cdc5.

  2001influential reference
• A protein interaction map for cell polarity development

  2001cited by this paper
• Press

  2001cited by this paper
• A comprehensive two-hybrid analysis to explore the yeast protein interactome

  2001cited by this paper
• Protein kinase Cdc15 activates the Dbf2-Mob1 kinase complex

  2001influential reference
• Overlapping and distinct roles of the duplicated yeast transcription factors Ace2p and Swi5p

  2001cited by this paper
• The Cbk1p Pathway Is Important for Polarized Cell Growth and Cell Separation in Saccharomyces cerevisiae

  2001cited by this paper
• Functional discovery via a compendium of expression profiles.

  2000cited by this paper
• Genomic expression programs in the response of yeast cells to environmental changes.

  2000influential reference
• A chemical switch for inhibitor-sensitive alleles of any protein kinase

  2000cited by this paper
• Control of cell divisions in the nervous system: symmetry and asymmetry.

  2000cited by this paper
• Cbk1p, a protein similar to the human myotonic dystrophy kinase, is essential for normal morphogenesis in Saccharomyces cerevisiae

  2000influential reference
• "Mutagenesis" by peptide aptamers identifies genetic network members and pathway connections.

  1999influential reference
• Regulated nuclear localisation of the yeast transcription factor Ace2p controls expression of chitinase (CTS1) in Saccharomyces cerevisiae

  1999cited by this paper
• Cell cycle synchronization.

  1999cited by this paper
• Distinct Regions of the Swi5 and Ace2 Transcription Factors Are Required for Specific Gene Activation*

  1999cited by this paper
• ペプチドアプタマーによる”変異原性”は遺伝的ネットワークメンバーと経路連結性を特定する

  1999cited by this paper
• Cell wall dynamics in yeast.

  1999cited by this paper
• Functional analysis of 150 deletion mutants in Saccharomyces cerevisiae by a systematic approach

  1999cited by this paper
• New yeast genes important for chromosome integrity and segregation identified by dosage effects on genome stability.

  1999cited by this paper
• New Potential Cell Wall Glucanases ofSaccharomyces cerevisiae and Their Involvement in Mating

  1998cited by this paper
• Early patterning of the C. elegans embryo.

  1998cited by this paper
• Asymmetric cell division

  1998cited by this paper
• Cluster analysis and display of genome-wide expression patterns.

  1998cited by this paper
• Comprehensive identification of cell cycle-regulated genes of the yeast Saccharomyces cerevisiae by microarray hybridization.

  1998influential reference
• Asymmetric cell division: lessons from flies and worms.

  1998cited by this paper
• Microbial asymmetric cell division: localization of cell fate determinants.

  1998cited by this paper
• The Swi5 transcription factor of Saccharomyces cerevisiae has a role in exit from mitosis through induction of the cdk-inhibitor Sic1 in telophase.

  1997cited by this paper
• Molecular evidence for an ancient duplication of the entire yeast genome

  1997cited by this paper
• Identification of asymmetrically localized determinant, Ash1p, required for lineage-specific transcription of the yeast HO gene.

  1996cited by this paper
• Role of negative regulation in promoter specificity of the homologous transcriptional activators Ace2p and Swi5p

  1996cited by this paper
• EGT2 gene transcription is induced predominantly by Swi5 in early G1

  1996cited by this paper
• Mother cell-specific HO expression in budding yeast depends on the unconventional myosin myo4p and other cytoplasmic proteins.

  1996cited by this paper
• Asymmetric accumulation of Ash1p in postanaphase nuclei depends on a myosin and restricts yeast mating-type switching to mother cells.

  1996cited by this paper
• An inhibitor of yeast cyclin-dependent protein kinase plays an important role in ensuring the genomic integrity of daughter cells.

  1994cited by this paper
• Interaction mating reveals binary and ternary connections between Drosophila cell cycle regulators.

  1994cited by this paper
• SWI5 instability may be necessary but is not sufficient for asymmetric HO expression in yeast.

  1993cited by this paper
• Regulating the HO endonuclease in yeast.

  1993cited by this paper
• Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase.

  1992cited by this paper
• Methods in enzymology vol 194 guide to yeast genetics and molecular biology

  1991cited by this paper
• Chitinase is required for cell separation during growth of Saccharomyces cerevisiae.

  1991influential reference
• Staining of bud scars and other cell wall chitin with calcofluor.

  1991influential reference
• The role of phosphorylation and the CDC28 protein kinase in cell cycle-regulated nuclear import of the S. cerevisiae transcription factor SWI5.

  1991cited by this paper
• The identification of a second cell cycle control on the HO promoter in yeast: cell cycle regulation of SW15 nuclear entry.

  1990cited by this paper
• A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

  1989cited by this paper
• Cell cycle control of the yeast HO gene: cis- and trans-acting regulators.

  1987cited by this paper
• Five SWI genes are required for expression of the HO gene in yeast.

  1984cited by this paper
• Molecular analysis of a cell lineage

  1983cited by this paper
• Homothallic switching of yeast mating type cassettes is initiated by a double-stranded cut in the MAT locus.

  1982cited by this paper
• Asymmetry and directionality in production of new cell types during clonal growth: the switching pattern of homothallic yeast.

  1979cited by this paper
• A mutant of yeast defective in cellular morphogenesis.

  1978cited by this paper
• Mating types in Saccharomyces: their convertibility and homothallism.

  1971cited by this paper

• In‐Cell Proteomics Enables High‐Resolution Temporal Profiling of Cell Cycle Progression and DNA Damage Response in Saccharomyces cerevisiae

  2025cites this paper
• A single-cell resolved genotype-phenotype map using genome-wide genetic and environmental perturbations

  2025cites this paper
• A short linear motif, conserved from yeast to human, binds to members of the Spa2 family of cortical scaffold proteins

  2025cites this paper
• Transcriptional heterogeneity shapes stress-adaptive responses in yeast

  2025cites this paper
• The impact of phenotypic heterogeneity on fungal pathogenicity and drug resistance

  2025cites this paper
• Overexpression of CBK1 or deletion of SSD1 confers fludioxonil resistance in yeast by suppressing Hog1 activation.

  2024cites this paper
• Perturbation-driven transcriptional heterogeneity impacts cell fitness

  2024cites this paper
• Protocol for FRAP-based estimation of nuclear import and export rates in single yeast cells

  2024cites this paper
• Global analysis of aging-related protein structural changes uncovers enzyme polymerization-based control of longevity

  2023cites this paper
• Mutants with Enhanced Multi-Stress Tolerance of Kluyveromyces marxianus and Their Ability for Ethanol Fermentation

  2023cites this paper
• TOR Complex 1: Orchestrating Nutrient Signaling and Cell Cycle Progression

  2023cites this paper
• Transient septin sumoylation steers a Fir1-Skt5 protein complex between the split septin ring

  2023cites this paper
• Identification of Morphogenesis-Related NDR Kinase Signaling Network and Its Regulation on Cold Tolerance in Maize

  2023cites this paper
• TOR complex 1 negatively regulates NDR kinase Cbk1 to control cell separation in budding yeast

  2023cites this paper
• On Learning Necessary and Sufficient Causal Graphs

  2023cites this paper
• The Mitogen-Activated Protein Kinase Slt2 Promotes Asymmetric Cell Cycle Arrest and Reduces TORC1-Sch9 Signaling in Yeast Lacking the Protein Phosphatase Ptc1

  2023cites this paper
• Characterization of cell-to-cell variation in nuclear transport rates and identification of its sources

  2022influential citation
• Microtubule integrity regulates budding yeast RAM pathway gene expression

  2022cites this paper
• Post-transcriptional control of fungal cell wall synthesis

  2022cites this paper
• The NDR kinase-MOB complex FgCot1-Mob2 regulates polarity and lipid metabolism in Fusarium graminearum.

  2021cites this paper
• Defining Functions of Mannoproteins in Saccharomyces cerevisiae by High-Dimensional Morphological Phenotyping

  2021cites this paper
• References

  2021cites this paper
• Analysis of local protein accumulation kinetics by live-cell imaging in yeast systems

  2021influential citation
• University of São Paulo “Luiz de Queiroz” College of Agriculture Comparative analysis of the transcriptional profile of the sugarcane smut pathogen during the interaction with resistant and susceptible genotypes

  2021cites this paper
• AtSYP71 Is Important for Plant Cell Wall Biosynthesis and Stress Adaptation.

  2021cites this paper
• NDR/LATS‐family protein kinase genes are indispensable for embryogenesis in Arabidopsis

  2021cites this paper
• Downregulation of the Tem1 GTPase by Amn1 after cytokinesis involves both nuclear import and SCF-mediated degradation.

  2021cites this paper
• The Hippo Signaling Pathway in Cancer: A Cell Cycle Perspective

  2021cites this paper
• The Role of the Cell Integrity Pathway in Septum Assembly in Yeast

  2021cites this paper
• Simulated microgravity accelerates aging in Saccharomyces cerevisiae.

  2021cites this paper
• Capturing hidden regulation based on noise change of gene expression level from single cell RNA-seq in yeast

  2021cites this paper
• MOB: Pivotal Conserved Proteins in Cytokinesis, Cell Architecture and Tissue Homeostasis

  2020cites this paper
• The kinetic landscape and interplay of protein networks in cytokinesis

  2020cites this paper
• Glycoside hydrolase family 18 chitinases: The known and the unknown.

  2020cites this paper
• Mosaic changes to the global transcriptome in response to inhibiting ribosome formation versus inhibition of ribosome function

  2020cites this paper
• Yeast as a Model to Understand Actin-Mediated Cellular Functions in Mammals—Illustrated with Four Actin Cytoskeleton Proteins

  2020cites this paper
• Cytokinesis in Eukaryotic Cells: The Furrow Complexity at a Glance

  2020cites this paper
• Mob Family Proteins: Regulatory Partners in Hippo and Hippo-Like Intracellular Signaling Pathways

  2020cites this paper
• Molecular Mechanisms Involved in the Multicellular Growth of Ustilaginomycetes

  2020cites this paper
• Systematic genetics and single‐cell imaging reveal widespread morphological pleiotropy and cell‐to‐cell variability

  2020cites this paper
• Modulation of Cell Identity by Modification of Nuclear Pore Complexes

  2020cites this paper
• FACT and Ash1 promote long-range and bidirectional nucleosome eviction at the HO promoter

  2020cites this paper
• Ndr/Lats kinases bind specific Mob-family coactivators through a conserved and modular interface.

  2020cites this paper
• Transcriptional control of hyphal morphogenesis in Candida albicans

  2020cites this paper
• Asymmetric Transcription Factor Partitioning During Yeast Cell Division Requires the FACT Chromatin Remodeler and Cell Cycle Progression

  2020cites this paper
• Generation of Inducible Gene-Switched GAL4 Expressed in the Drosophila Female Germline Stem Cell Niche

  2019cites this paper
• The phosphatase gene MaCdc14 negatively regulates UV-B tolerance by mediating the transcription of melanin synthesis-related genes and contributes to conidiation in Metarhizium acridum

  2019cites this paper
• Regulation of cell polarity by the cell cycle in Saccharomyces cerevisiae

  2019cites this paper
• Distinct Roles of Myosin-II Isoforms in Cytokinesis under Normal and Stressed Conditions

  2019cites this paper
• Exploring endocytic compartment morphology with systematic genetics and single cell image analysis

  2019cites this paper
• Extensive loss of cell-cycle and DNA repair genes in an ancient lineage of bipolar budding yeasts

  2019cites this paper
• A Potential Lock-Type Mechanism for Unconventional Secretion in Fungi

  2019cites this paper
• Investigating Common Pathogenic Mechanisms between Homo sapiens and Different Strains of Candida albicans for Drug Design: Systems Biology Approach via Two-Sided NGS Data Identification

  2019cites this paper
• Multiple Negative Regulators Restrict Recruitment of the SWI/SNF Chromatin Remodeler to the HO Promoter in Saccharomyces cerevisiae

  2019cites this paper
• Genetic screens identify multiple negative regulators that additively restrict recruitment of the SWI/SNF chromatin remodeler to the HO promoter in Saccharomyces cerevisiae

  2019cites this paper
• Septum Formation and Cytokinesis in Ascomycete Fungi

  2019cites this paper
• Gene regulatory network reconstruction using single-cell RNA sequencing of barcoded genotypes in diverse environments

  2019cites this paper
• Glucanases and Chitinases.

  2019cites this paper
• Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan

  2018cites this paper
• Cell-cycle control of cell polarity in yeast

  2018cites this paper
• Transcriptional timing and noise of yeast cell cycle regulators—a single cell and single molecule approach

  2018cites this paper
• Intrinsic polarization cues interfere with pheromone gradient sensing in S. cerevisiae

  2018cites this paper
• Asymmetric secretion in budding yeast reinforces daughter cell identity

  2018influential citation
• A PxL motif promotes timely cell cycle substrate dephosphorylation by the Cdc14 phosphatase

  2018cites this paper
• From Genes to Networks: The Regulatory Circuitry Controlling Candida albicans Morphogenesis.

  2018cites this paper
• A cell separation checkpoint that enforces the proper order of late cytokinetic events

  2018cites this paper
• The function of yeast CAP family proteins in lipid export, mating, and pathogen defense

  2018cites this paper
• Single‐cell profiling screen identifies microtubule‐dependent reduction of variability in signaling

  2018cites this paper
• Mob-family kinase co-activators bind cognate Ndr/Lats kinases through conserved and modular interface

  2018cites this paper
• Members of Glycosyl-Hydrolase Family 17 of A. fumigatus Differentially Affect Morphogenesis

  2018cites this paper
• Daughter-cell-specific modulation of nuclear pore complexes controls cell cycle entry during asymmetric division

  2018cites this paper
• Evolutionary history of Mo25 gene in plants, a component of RAM/MOR signaling network.

  2018cites this paper
• Two Antagonistic Hippo Signaling Circuits Set the Division Plane at the Medial Position in the Ciliate Tetrahymena

  2018cites this paper
• The budding‐yeast RWD protein Csm1 scaffolds diverse protein complexes through a conserved structural mechanism

  2018cites this paper
• Role of the Hof1–Cyk3 interaction in cleavage-furrow ingression and primary-septum formation during yeast cytokinesis

  2018cites this paper
• Transcriptome analysis reveals the differences between cellular response to ribosomal stress and translational stress

  2017cites this paper
• Cell-specific modulation of nuclear pore complexes controls cell cycle entry during asymmetric division

  2017cites this paper
• From birth to birth A cell cycle control network of S. cerevisiae

  2017cites this paper
• The Hippo Pathway Maintains the Equatorial Division Plane in the Ciliate Tetrahymena

  2017cites this paper
• Explorer Trypanosoma brucei MOB 1 is required for accurate and efficient cytokinesis but not for exit from mitosis

  2017cites this paper
• Mechanics and regulation of cytokinesis in budding yeast.

  2017cites this paper
• The Adder Phenomenon Emerges from Independent Control of Pre- and Post-Start Phases of the Budding Yeast Cell Cycle.

  2017cites this paper
• Analysis of cell cycle parameters during the transition from unhindered growth to ribosomal and translational stress conditions

  2017cites this paper
• Saccharomyces cerevisiae as a Model for Space Biology

  2017cites this paper
• Protein Phosphorylation is an

  2017cites this paper
• Spatial and temporal signal processing and decision making by MAPK pathways

  2017cites this paper
• Nutritional Control of Chronological Aging and Heterochromatin in Saccharomyces cerevisiae

  2017cites this paper
• The mediator of transcription in Candida albicans: roles in cell wall biogenesis, morphogenesis and host-pathogen interactions

  2017cites this paper
• The FACT complex and cell cycle progression are essential to maintain asymmetric transcription factor partitioning during cell division

  2016cites this paper
• The Role of Transcription Factors at Antisense-Expressing Gene Pairs in Yeast

  2016cites this paper
• Actomyosin ring driven cytokinesis in budding yeast

  2016cites this paper
• Stochastic modeling of cell growth with symmetric or asymmetric division.

  2016cites this paper
• Pairs in Yeast.

  2016cites this paper
• Mechanotransduction as an Adaptation to Gravity

  2016cites this paper
• Fungal chitinases: function, regulation, and potential roles in plant/pathogen interactions

  2016influential citation
• The Harvard community has made this article openly available. Please share how this access benefits you. Your story matters.

  2016cites this paper
• Cellular localization of Sun4p and its interaction with proteins in the yeast birth scar

  2016influential citation
• The CDK-APC/C Oscillator Predominantly Entrains Periodic Cell-Cycle Transcription.

  2016cites this paper
• Identification and characterization of transcription factors involved in morphogenesis in the human fungal pathogen Candida albicans

  2016influential citation
• The final cut: cell polarity meets cytokinesis at the bud neck in S. cerevisiae

  2016cites this paper