Mammary Tumor Formation in p 53-and BRCA 1-deficient Mice 1

No abstract is available for this paper.

• Publication year

  1998

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Advances in Brief Loss of Heterozygosity in Familial Tumors from Three BRCAJ-linked Kindreds'

  2013cited by this paper
• p53 mutations in BRCA1-associated familial breast cancer.

  1998cited by this paper
• BRCA1 regulates p53-dependent gene expression.

  1998cited by this paper
• BRCA1 physically associates with p53 and stimulates its transcriptional activity

  1998cited by this paper
• BRCA1 required for transcription-coupled repair of oxidative DNA damage.

  1998cited by this paper
• Identification of a BRCA1-associated kinase with potential biological relevance

  1998cited by this paper
• Thymic lymphomas in mice with a truncating mutation in Brca2.

  1998cited by this paper
• Characterization of Brca1 Deficient Mice

  1998cited by this paper
• BRCA1 protein is linked to the RNA polymerase II holoenzyme complex via RNA helicase A

  1998cited by this paper
• BAP1: a novel ubiquitin hydrolase which binds to the BRCA1 RING finger and enhances BRCA1-mediated cell growth suppression

  1998cited by this paper
• Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage.

  1997cited by this paper
• The risk of cancer associated with specific mutations of BRCA1 and BRCA2 among Ashkenazi Jews.

  1997cited by this paper
• Association of BRCA1 with Rad51 in mitotic and meiotic cells.

  1997cited by this paper
• p53, the Cellular Gatekeeper Review for Growth and Division

  1997cited by this paper
• Tumorigenesis and a DNA repair defect in mice with a truncating Brca2 mutation

  1997cited by this paper
• Brca2 is required for embryonic cellular proliferation in the mouse.

  1997cited by this paper
• Localization of BRCA1 and a splice variant identifies the nuclear localization signal

  1997cited by this paper
• Partial rescue of Brca15–6 early embryonic lethality by p53 or p21 null mutation

  1997cited by this paper
• Targeted mutations of breast cancer susceptibility gene homologs in mice: lethal phenotypes of Brca1, Brca2, Brca1/Brca2, Brca1/p53, and Brca2/p53 nullizygous embryos.

  1997cited by this paper
• The Nuclear Localization Sequences of the BRCA1 Protein Interact with the Importin-α Subunit of the Nuclear Transport Signal Receptor*

  1996cited by this paper
• Lessons from the p53 mutant mouse.

  1996cited by this paper
• The tumor suppressor gene Brca1 is required for embryonic cellular proliferation in the mouse.

  1996cited by this paper
• The role of individual susceptibility in cancer burden related to environmental exposure.

  1996cited by this paper
• BRCA1 is a 220-kDa nuclear phosphoprotein that is expressed and phosphorylated in a cell cycle-dependent manner.

  1996cited by this paper
• Gene targeting in kidney development.

  1996cited by this paper
• Identification of a RING protein that can interact in vivo with the BRCA1 gene product

  1996cited by this paper
• Evidence for a transcriptional activation function of BRCA1 C-terminal region.

  1996cited by this paper
• Localization of BRCA 1 and a Splice Variant Identifies the Nuclear Localization Signal

  1996cited by this paper
• Brca1 deficiency results in early embryonic lethality characterized by neuroepithelial abnormalities

  1996cited by this paper
• Inactivation of the mouse Brca1 gene leads to failure in the morphogenesis of the egg cylinder in early postimplantation development.

  1996cited by this paper
• Complete genomic sequence and analysis of 117 kb of human DNA containing the gene BRCA1.

  1996cited by this paper
• Hormones and mammary carcinogenesis in mice, rats, and humans: a unifying hypothesis.

  1995cited by this paper
• Mouse Brca1: localization sequence analysis and identification of evolutionarily conserved domains.

  1995cited by this paper
• High-frequency developmental abnormalities in p53-deficient mice.

  1995cited by this paper
• A subset of p53-deficient embryos exhibit exencephaly

  1995cited by this paper
• Murine Brca1: sequence and significance for human missense mutations.

  1995cited by this paper
• Deficiency of p53 accelerates mammary tumorigenesis in Wnt-1 transgenic mice and promotes chromosomal instability.

  1995cited by this paper
• Tumor spectrum analysis in p53-mutant mice.

  1994influential reference
• Confirmation of BRCA1 by analysis of germline mutations linked to breast and ovarian cancer in ten families

  1994cited by this paper
• A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1.

  1994cited by this paper
• Cooperative tumorigenic effects of germline mutations in Rb and p53

  1994cited by this paper
• p53-deficient mice are extremely susceptible to radiation-induced tumorigenesis

  1994influential reference
• Genetic analysis of the BRCA1 region in a large breast/ovarian family: refinement of the minimal region containing BRCA1.

  1993cited by this paper
• Spontaneous and carcinogen–induced tumorigenesis in p53–deficient mice

  1993cited by this paper
• WT-1 is required for early kidney development.

  1993cited by this paper
• Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

  1993cited by this paper
• Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

  1992cited by this paper
• p53 mutations in breast cancer.

  1992cited by this paper
• Allele losses in the region 17q12–21 in familial breast and ovarian cancer involve the wild–type chromosome

  1992cited by this paper
• Effects of an Rb mutation in the mouse

  1992cited by this paper
• Genetic analysis of breast cancer in the cancer and steroid hormone study.

  1991cited by this paper
• Loss of chromosome 17p13 sequences and mutation of p53 in human breast carcinomas.

  1991cited by this paper
• Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms.

  1990cited by this paper
• Patterns of expression of the p53 tumour suppressor in human breast tissues and tumours in situ and in vitro

  1990cited by this paper
• A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

  1986cited by this paper
• Growth regulation of a cellular tumour antigen, p53, in nontransformed cells

  1984cited by this paper

• Molecular Cancer esearch Damage and Cellular Stress Responses c 2 Modulates Spontaneous and Radiation-Induced R origenesis in Apcmin / + Mice

  2010cites this paper
• Conditional Inactivation of Brca1, p53 and Rb in Mouse Ovaries Results in the Development of Leiomyosarcomas

  2009cites this paper
• Heterozygosity for a mutation in Brca1 or Atm does not increase susceptibility to ENU-induced mammary tumors in Apc(Min)/+ mice.

  2001cites this paper