Effects of pharmaceutical pollutants and their mixtures on aquatic organisms – with particular focus on reproduction and endocrine function in a fish model species.

Tara J Thrupp

Published 2016 in Unknown venue

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2016
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Unknown venue
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Biology, Medicine, Environmental Science
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REFERENCES

Comparison of in vitro estrogenic activity and estrogen concentrations in source and treated waters from 25 U.S. drinking water treatment plants.
2017cited by this paper
Reproductive effects in fathead minnows (Pimphales promelas) following a 21 d exposure to 17α-ethinylestradiol.
2016cited by this paper
Human metabolites and transformation products of cyclophosphamide and ifosfamide: analysis, occurrence and formation during abiotic treatments
2016cited by this paper
Toxicological and ecotoxicological risk‐based prioritization of pharmaceuticals in the natural environment
2016cited by this paper
Internal exposure dynamics drive the Adverse Outcome Pathways of synthetic glucocorticoids in fish
2016cited by this paper
A rational approach to selecting and ranking some pharmaceuticals of concern for the aquatic environment and their relative importance compared with other chemicals
2016cited by this paper
Toxicity of the mixture of selected antineoplastic drugs against aquatic primary producers
2016cited by this paper
Occurrence of glucocorticoids discharged from a sewage treatment plant in Japan and the effects of clobetasol propionate exposure on the immune responses of common carp (Cyprinus carpio) to bacterial infection
2016cited by this paper
Improving environmental risk assessment of human pharmaceuticals.
2015influential reference
Environmental concentrations of anti-androgenic pharmaceuticals do not impact sexual disruption in fish alone or in combination with steroid oestrogens.
2015cited by this paper
Nuclear Receptors: From Structure to the Clinic
2015cited by this paper
From single chemicals to mixtures--reproductive effects of levonorgestrel and ethinylestradiol on the fathead minnow.
2015cited by this paper
Pharmaceuticals in the Aquatic Environment: a Short Summary of Current Knowledge and the Potential Impacts on Aquatic Biota and Humans
2015cited by this paper
Mixture effects of levonorgestrel and ethinylestradiol: estrogenic biomarkers and hormone receptor mRNA expression during sexual programming.
2015cited by this paper
Environmental side effects of pharmaceutical cocktails: what we know and what we should know.
2014cited by this paper
An integrated approach for prioritizing pharmaceuticals found in the environment for risk assessment, monitoring and advanced research.
2014cited by this paper
INTRODUCTION TO ENDOCRINE DISRUPTING CHEMICALS (EDCs) A GUIDE FOR PUBLIC INTEREST ORGANIZATIONS AND POLICY-MAKERS
2014cited by this paper
Transient exposure to environmental estrogen affects embryonic development of brown trout (Salmo trutta fario).
2014cited by this paper
Quantitative Cross-Species Extrapolation between Humans and Fish: The Case of the Anti-Depressant Fluoxetine
2014cited by this paper
Toxicities of four anti-neoplastic drugs and their binary mixtures tested on the green alga Pseudokirchneriella subcapitata and the cyanobacterium Synechococcus leopoliensis.
2014cited by this paper
Prioritising anticancer drugs for environmental monitoring and risk assessment purposes.
2014cited by this paper
Pharmaceuticals in the environment: scientific evidence of risks and its regulation
2014influential reference
ROR nuclear receptors: structures, related diseases, and drug discovery
2014cited by this paper
Adverse outcome pathway (AOP) development I: strategies and principles.
2014cited by this paper
The progestin levonorgestrel disrupts gonadotropin expression and sex steroid levels in pubertal roach (Rutilus rutilus).
2014cited by this paper
Membrane estrogen receptors - is it an alternative way of estrogen action?
2013cited by this paper
Effects of low concentrations of the antiprogestin mifepristone (RU486) in adults and embryos of zebrafish (Danio rerio): 2. Gene expression analysis and in vitro activity.
2013cited by this paper
Metabolic and reproductive effects of relatively low concentrations of beclomethasone dipropionate, a synthetic glucocorticoid, on fathead minnows.
2013cited by this paper
Evidence of small modulation of ethinylestradiol induced effects by concurrent exposure to trenbolone in male eelpout Zoarces viviparus.
2013cited by this paper
Physiological roles of glucocorticoids during early embryonic development of the zebrafish (Danio rerio)
2013cited by this paper
Enzyme immunoassay and enzyme-linked immunosorbent assay.
2013cited by this paper
Estrogen receptor function and regulation in fish and other vertebrates.
2013cited by this paper
Several synthetic progestins with different potencies adversely affect reproduction of fish.
2013cited by this paper
Zebrafish and steroids: what do we know and what do we need to know?
2013cited by this paper
Long-term survival of participants in the prostate cancer prevention trial.
2013cited by this paper
Fate of drugs during wastewater treatment
2013cited by this paper
High-throughput sequencing and pathway analysis reveal alteration of the pituitary transcriptome by 17α-ethynylestradiol (EE2) in female coho salmon, Oncorhynchus kisutch.
2013cited by this paper
Achieving pH control in microalgal cultures through fed-batch addition of stoichiometrically-balanced growth media
2013cited by this paper
A Review of Hypothalamic-Pituitary-Adrenal Axis Function in Chronic Fatigue Syndrome
2013cited by this paper
EU-wide monitoring survey on emerging polar organic contaminants in wastewater treatment plant effluents.
2013influential reference
Anti-androgens act jointly in suppressing spiggin concentrations in androgen-primed female three-spined sticklebacks - prediction of combined effects by concentration addition.
2013cited by this paper
The Read-Across Hypothesis and Environmental Risk Assessment of Pharmaceuticals
2013cited by this paper
Seven benzimidazole pesticides combined at sub-threshold levels induce micronuclei in vitro
2013cited by this paper
Rapid steroid hormone actions initiated at the cell surface and the receptors that mediate them with an emphasis on recent progress in fish models.
2012cited by this paper
Human pharmaceuticals in the aquatic environment: a review of recent toxicological studies and considerations for toxicity testing.
2012cited by this paper
Predicted‐no‐effect concentrations for the steroid estrogens estrone, 17β‐estradiol, estriol, and 17α‐ethinylestradiol
2012cited by this paper
Global Synthesis and Critical Evaluation of Pharmaceutical Data Sets Collected from River Systems
2012cited by this paper
Screening and human health risk assessment of pharmaceuticals and their transformation products in Dutch surface waters and drinking water.
2012cited by this paper
Field surveys reveal the presence of anti-androgens in an effluent-receiving river using stickleback-specific biomarkers.
2012cited by this paper
Prioritization of chemicals in the aquatic environment based on risk assessment: analytical, modeling and regulatory perspective.
2012cited by this paper
Glucocorticoid regulation of inflammation and its functional correlates: from HPA axis to glucocorticoid receptor dysfunction
2012cited by this paper
Screening Estrogenic Activities of Chemicals or Mixtures In Vivo Using Transgenic (cyp19a1b-GFP) Zebrafish Embryos
2012cited by this paper
Functional Significance of GnRH and Kisspeptin, and Their Cognate Receptors in Teleost Reproduction
2012cited by this paper
Effects of a glucocorticoid receptor agonist, dexamethasone, on fathead minnow reproduction, growth, and development
2012cited by this paper
Prioritising pharmaceuticals for environmental risk assessment: Towards adequate and feasible first-tier selection.
2012cited by this paper
Human therapeutic plasma levels of the selective serotonin reuptake inhibitor (SSRI) sertraline decrease serotonin reuptake transporter binding and shelter-seeking behavior in adult male fathead minnows.
2012cited by this paper
The advantages of flow cytometry in comparison to fluorometric measurement in algal toxicity test
2012cited by this paper
Toxic effect of the combined antibiotics ciprofloxacin, lincomycin, and tylosin on two species of marine diatoms.
2012cited by this paper
Fish models for ecotoxicology
2012cited by this paper
Leaky Gut and Autoimmune Diseases
2012cited by this paper
Algae Pseudokircheriella subcapitata in environmental hazard evaluation of chemicals and synthetic nanoparticles
2011cited by this paper
olecular mechanisms of steroid receptor-mediated actions by synthetic rogestins used in HRT and contraception
2011cited by this paper
CHEM Trust ’ s response to the SCHER / SCENIHR / SCCS pre-consultation opinion on " Toxicity and Assessment of Chemical Mixtures "
2011cited by this paper
Early drug discovery and the rise of pharmaceutical chemistry.
2011influential reference
Synthetic glucocorticoids in the environment: first results on their potential impacts on fish.
2011cited by this paper
Extra-adrenal glucocorticoids and mineralocorticoids: evidence for local synthesis, regulation, and function.
2011cited by this paper
5α-Dihydrotestosterone is a potent androgen in the fathead minnow (Pimephales promelas).
2011cited by this paper
Effects of a complex mixture of therapeutic drugs on unicellular algae Pseudokirchneriella subcapitata.
2011cited by this paper
Occurrence and fate of human pharmaceuticals in the environment.
2010cited by this paper
Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment
2010cited by this paper
Impacts of an anti-androgen and an androgen/anti-androgen mixture on the metabolite profile of male fathead minnow urine.
2010cited by this paper
Predicted critical environmental concentrations for 500 pharmaceuticals.
2010cited by this paper
Multi-residue analytical method for human pharmaceuticals and synthetic hormones in river water and sewage effluents by solid-phase extraction and liquid chromatography-tandem mass spectrometry.
2010cited by this paper
Workshop Report: River Basin-Specific Pollutants - Identification and Monitoring
2010cited by this paper
Characterization of the androgen‐sensitive MDA‐kb2 cell line for assessing complex environmental mixtures
2010influential reference
Pharmaceutical Formulation Facilities as Sources of Opioids and Other Pharmaceuticals to Wastewater Treatment Plant Effluents
2010cited by this paper
High-resolution mass spectrometric identification and quantification of glucocorticoid compounds in various wastewaters in the Netherlands.
2010cited by this paper
Proposing a pH stabilised nutrient medium for algal growth bioassays.
2010cited by this paper
Reproductive responses in fathead minnow and Japanese medaka following exposure to a synthetic progestin, Norethindrone.
2010cited by this paper
Stress and fish reproduction: the roles of allostasis and hormesis.
2010cited by this paper
Pharmaceuticals in the aquatic environment: A critical review of the evidence for health effects in fish
2010influential reference
Hepatic transcriptomic and metabolomic responses in the Stickleback (Gasterosteus aculeatus) exposed to ethinyl-estradiol.
2010cited by this paper
Potential Relevance of Bell-Shaped and U-Shaped Dose-Responses for the Therapeutic Targeting of Angiogenesis in Cancer
2010cited by this paper
Effects of Ethinylestradiol on Medaka (Oryzias latipes) as Measured by Sperm Motility and Fertilization Success
2009cited by this paper
Occurrence of pharmaceuticals in Taiwan's surface waters: impact of waste streams from hospitals and pharmaceutical production facilities.
2009influential reference
Normalization of qRT-PCR data: the necessity of adopting a systematic, experimental conditions-specific, validation of references.
2009cited by this paper
Plasma membrane estrogen receptors.
2009influential reference
Antibiotics in the aquatic environment--a review--part I.
2009cited by this paper
Human health risk assessment from the presence of human pharmaceuticals in the aquatic environment.
2009cited by this paper
Effects of binary mixtures of estrogen and antiestrogens on Japanese medaka (Oryzias latipes).
2009cited by this paper
Pharmaceuticals and Personal Care Products in the Environment CONTAMINATION OF SURFACE, GROUND, AND DRINKING WATER FROM PHARMACEUTICAL PRODUCTION
2009cited by this paper
The genomic transcriptional response of female fathead minnows (Pimephales promelas) to an acute exposure to the androgen, 17beta-trenbolone.
2009cited by this paper
Endocrine disrupting chemicals in fish: developing exposure indicators and predictive models of effects based on mechanism of action.
2009cited by this paper
Pharmaceuticals and Personal Care Products in the Environment EFFECTS OF SYNTHETIC GESTAGENS ON FISH REPRODUCTION
2009cited by this paper
Differential regulation of gonadotropins (FSH and LH) and growth hormone (GH) by neuroendocrine, endocrine, and paracrine factors in the zebrafish--an in vitro approach.
2009cited by this paper
A national risk assessment for intersex in fish arising from steroid estrogens
2009cited by this paper
Pharmaceuticals and Personal Care Products in the Environment CYTOTOXIC DRUGS IN DRINKING WATER: A PREDICTION AND RISK ASSESSMENT EXERCISE FOR THE THAMES CATCHMENT IN THE UNITED KINGDOM
2009cited by this paper
Evolutionary history and functional characterization of androgen receptor genes in jawed vertebrates.
2009cited by this paper
Protecting aquatic organisms from chemicals: the harsh realities
2009cited by this paper
Pharmaceutical metabolites in the environment: Analytical challenges and ecological risks
2009cited by this paper

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