The Immunobiology of Tourette's Disorder, Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcus, and Related Disorders: A Way Forward

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Journal of child and adolescent psychopharmacology

• Publication date

  2010-08-01

• Fields of study

  Biology, Medicine, Psychology

• Identifiers
  DOI 10.1089/cap.2010.0043PMID 20807070PMCID PMC4003464
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2009influential reference
• The PANDAS subgroup of tic disorders and childhood-onset obsessive-compulsive disorder.

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• Serial Immune Markers Do Not Correlate With Clinical Exacerbations in Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections

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• Cardiac involvement in children with PANDAS.

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• Psychosocial stress predicts future symptom severities in children and adolescents with Tourette syndrome and/or obsessive-compulsive disorder.

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• Antineuronal antibody status and phenotype analysis in Tourette's syndrome

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• Dietary Supplementation of Probiotic Bacillus polyfermenticus, Bispan Strain, Modulates Natural Killer Cell and T Cell Subset Populations and Immunoglobulin G Levels in Human Subjects

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• Contemporary assessment and pharmacotherapy of Tourette syndrome

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• Genomic profiles for human peripheral blood T cells, B cells, natural killer cells, monocytes, and polymorphonuclear cells: comparisons to ischemic stroke, migraine, and Tourette syndrome.

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• Group A streptococcus (GAS) carbohydrate as an immunogen for protection against GAS infection.

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• Streptococcal mimicry and antibody-mediated cell signaling in the pathogenesis of Sydenham's chorea

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• Identification of pyruvate kinase as an antigen associated with Tourette syndrome.

  2006influential reference
• Neuronal surface glycolytic enzymes are autoantigen targets in post-streptococcal autoimmune CNS disease.

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• Dopamine by itself activates either D2, D3 or D1/D5 dopaminergic receptors in normal human T-cells and triggers the selective secretion of either IL-10, TNFα or both

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• Dopamine by itself activates either D2, D3 or D1/D5 dopaminergic receptors in normal human T-cells and triggers the selective secretion of either IL-10, TNFalpha or both.

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• Faculty Opinions recommendation of Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.

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• Association Between Streptococcal Infection and Obsessive-Compulsive Disorder, Tourette's Syndrome, and Tic Disorder

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• β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression

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  2005influential reference
• Differential effects of β-lactams on human IFN-γ activity

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• ntibiotic Prophylaxis with Azithromycin or Penicillin or Childhood-Onset Neuropsychiatric Disorders

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• Differential effects of beta-lactams on human IFN-gamma activity.

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• Treatment of Sydenham's Chorea with Intravenous Immunoglobulin, Plasma Exchange, or Prednisone

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• Detecting pediatric autoimmune neuropsychiatric disorders associated with streptococcus in children with obsessive-compulsive disorder and tics.

  2004influential reference
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• A Murine Model for Neuropsychiatric Disorders Associated with Group A β-Hemolytic Streptococcal Infection

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• Molecular basis of group A streptococcal virulence.

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• Benzylpenicillin differentially conjugates to IFN‐γ, TNF‐α, IL‐1β, IL‐4 and IL‐13 but selectively reduces IFN‐γ activity

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• Benzylpenicillin differentially conjugates to IFN-gamma, TNF-alpha, IL-1beta, IL-4 and IL-13 but selectively reduces IFN-gamma activity.

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• Mimicry and autoantibody-mediated neuronal cell signaling in Sydenham chorea

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• Prevalence of tic disorders and Tourette syndrome in a Swedish school population

  2003influential reference
• Anti–basal ganglia antibodies in acute and persistent Sydenham’s chorea

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• An animal model of Tourette's syndrome.

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• Clinical use and interpretation of group A streptococcal antibody tests: a practical approach for the pediatrician or primary care physician

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• Retrospective evaluation of stuttering cases with and without PANDAS comorbidity

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• Tourette's Disorder

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• Increased Compulsivity in Adulthood after Early Adolescence Immune Activation: Preclinical Evidence

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• Further reading

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• Index

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• Guidelines Based on Expert Survey and Consensus

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