TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer’s disease mouse models

Jay and colleagues show that TREM2 deficiency reduces the number of macrophages infiltrating the brain and is protective against disease pathogenesis in mouse models of Alzheimer’s disease.

• Publication year

  2015

• Venue

  Journal of Experimental Medicine

• Publication date

  2015-03-09

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1084/jem.20142322PMID 25732305PMCID 4354365
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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