Unused Natural Variation Can Lift Yield Barriers in Plant Breeding

Natural biodiversity is an underexploited sustainable resource that can enrich the genetic basis of cultivated plants with novel alleles that improve productivity and adaptation. We evaluated the progress in breeding for increased tomato (Solanum lycopersicum) yield using genotypes carrying a pyramid of three independent yield-promoting genomic regions introduced from the drought-tolerant green-fruited wild species Solanum pennellii. Yield of hybrids parented by the pyramided genotypes was more than 50% higher than that of a control market leader variety under both wet and dry field conditions that received 10% of the irrigation water. This demonstration of the breaking of agricultural yield barriers provides the rationale for implementing similar strategies for other agricultural organisms that are important for global food security.

• Publication year

  2004

• Venue

  PLoS Biology

• Publication date

  2004-08-24

• Fields of study

  Agricultural and Food Sciences, Medicine, Biology, Environmental Science

• Identifiers
  DOI 10.1371/journal.pbio.0020245PMID 15328532PMCID 514488
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Naturally occurring genetic variation in Arabidopsis thaliana.

  2004cited by this paper
• Published online in Wiley InterScience (www.interscience.wiley.com). DOI: 10.1002/cfg.393 Conference Review

  2004cited by this paper
• Advanced Backcross QTL Analysis in Barley

  2004cited by this paper
• Real Time QTL of complex phenotypes in tomato interspecific introgression lines.

  2004influential reference
• Genetic Dissection of Complex Traits with Chromosome Substitution Strains of Mice

  2004cited by this paper
• Global Food Security: Challenges and Policies

  2003cited by this paper
• Advanced backcross QTL analysis for the identification of quantitative trait loci alleles from wild relatives of wheat (Triticum aestivum L.)

  2003cited by this paper
• Mapping of yield-related QTLs in pepper in an interspecific cross of Capsicum annuum and C. frutescens

  2003cited by this paper
• Advanced backcross QTL analysis in barley (Hordeum vulgare L.)

  2003cited by this paper
• Functional Divergence of a Syntenic Invertase Gene Family in Tomato, Potato, and Arabidopsis1

  2003cited by this paper
• From plant genomics to breeding practice.

  2003cited by this paper
• Identification of quantitative trait loci for yield and yield components in an advanced backcross population derived from the Oryza sativa variety IR64 and the wild relative O. rufipogon

  2003cited by this paper
• Introgression of a quantitative trait locus for yield from Glycine soja into commercial soybean cultivars

  2003cited by this paper
• Two tightly linked QTLs modify tomato sugar content via different physiological pathways

  2001cited by this paper
• Improving plant breeding with exotic genetic libraries

  2001influential reference
• A recombination hotspot delimits a wild-species quantitative trait locus for tomato sugar content to 484 bp within an invertase gene.

  2000cited by this paper
• Advanced backcross QTL analysis of tomato. II. Evaluation of near-isogenic lines carrying single-donor introgressions for desirable wild QTL-alleles derived from Lycopersicon hirsutum and L. pimpinellifolium

  1998cited by this paper
• Genome projects and gene pools: new germplasm for plant breeding?

  1998cited by this paper
• Plant Evolution under Domestication

  1998cited by this paper
• Seed banks and molecular maps: unlocking genetic potential from the wild.

  1997influential reference
• Exploitation of wild Cicer species for yield improvement in chickpea

  1997cited by this paper
• Less-than-additive epistatic interactions of quantitative trait loci in tomato.

  1996cited by this paper
• An introgression line population of Lycopersicon pennellii in the cultivated tomato enables the identification and fine mapping of yield-associated QTL.

  1995cited by this paper
• Interpretation and Use of Estimates of Heritability and Genetic Variances in Plant Breeding1

  1969cited by this paper
• Crop Improvement by Utilizing Wild Species

  year unknowncited by this paper

• Floristic composition of Shamansir mountain, West Saudi Arabia, as sustainable economic resources

  2025influential citation
• Salt Tolerance Potential of Selected Solanum pennellii Introgression Lines: Unique Shoot and Root Responses

  2025cites this paper
• Modulating the fruit morphology of traditional melon varieties: insights into IL × genetic background interactions

  2025cites this paper
• Analysis and Evaluation of Quality Traits of Peanut Varieties with Near Infra-Red Spectroscopy Technology

  2025cites this paper
• Tolerance Mechanisms and Management Strategies to Combat Heat Stress in Fruit Crops

  2025cites this paper
• Predicting hybrid fitness: the effects of ploidy and complex ancestry

  2025cites this paper
• Genome-Wide, High-Density Genotyping Approaches for Plant Germplasm Characterisation (Methods and Applications)

  2025cites this paper
• Genetic architecture of cowpea domestication: QTL mapping and comparison shed new light on the dual domestication events

  2025cites this paper
• Harnessing the crop wild relatives in genetic improvement of eggplant, potato and tomato

  2024cites this paper
• From wild to mild and back again: envisioning a new model of crop improvement strategies

  2024cites this paper
• Deep learning the cis-regulatory code for gene expression in selected model plants

  2024cites this paper
• Applying a non-GMO breeding approach with an identified natural variation to reduce food allergen Len c3 in Lens culinaris seeds

  2024cites this paper
• Evaluation of the Potential Use of Wild Relatives of Tomato (Solanum pennellii) to Improve Yield and Fruit Quality Under Low-Input and High-Salinity Cultivation Conditions

  2024cites this paper
• Genetic diversity and distinctiveness of Chilean Limachino tomato (Solanum lycopersicum L.) reveal an in situ conservation during the 20th century

  2023cites this paper
• Form and contour: breeding and genetics of organ shape from wild relatives to modern vegetable crops

  2023cites this paper
• Impacts of climate change on vegetable production and ways to overcome them

  2023cites this paper
• Morphological trait evolution in Solanum (Solanaceae): evolutionary lability of key taxonomic characters

  2023cites this paper
• Transient overdominance, coadaptation, and the fixability of heterosis

  2023cites this paper
• Characterization of the genetic composition and establishment of a core collection for the INERA Robusta coffee (Coffea canephora) field genebank from the Democratic Republic of the Congo

  2023cites this paper
• Studies on the Molecular Basis of Heterosis in Arabidopsis thaliana and Vegetable Crops

  2023cites this paper
• The genomics of linkage drag in inbred lines of sunflower

  2023cites this paper
• Improvement of heat stress tolerance in soybean (Glycine max L), by using conventional and molecular tools

  2022cites this paper
• History of Tomato Cultivation in Chile: The Limachino Tomato Case

  2022cites this paper
• Weight Gain of Spodoptera frugiperda Larvae (Lepidoptera: Noctuidae) on Leaf and Floral Tissues of Silphium integrifolium (Asterales: Asteraceae) Differs by Plant Genotype

  2022cites this paper
• De novo Domestication in the Multi-omics Era.

  2022cites this paper
• The genomics of linkage drag in sunflower

  2022cites this paper
• EXPLORING THE GENETIC RESOURCES OF COTTON

  2022cites this paper
• Are crop deep roots always beneficial for combating drought: A review of root structure and function, regulation and phenotyping

  2022cites this paper
• Unravelling the physiological basis of salinity stress tolerance in cultivated and wild rice species.

  2022cites this paper
• Transcriptomic and splicing changes underlying tomato responses to combined water and nutrient stress

  2022cites this paper
• Drought and nitrogen stress effects and tolerance mechanisms in tomato: a review

  2022cites this paper
• Diurnal stomatal apertures profile and density ratios affect whole-canopy conductance, drought response, water-use efficiency and yield

  2022cites this paper
• A suberized exodermis is required for tomato drought tolerance

  2022cites this paper
• A pan-genome data structure induced by pooled sequencing facilitates variant mining in heterogeneous germplasm

  2022cites this paper
• An overview of salinity stress, mechanism of salinity tolerance and strategies for its management in cotton

  2022cites this paper
• Alien introgression and morpho-agronomic characterization of diploid progenies of Solanum lycopersicoides monosomic alien addition lines (MAALs) toward pre-breeding applications in tomato (S. lycopersicum)

  2021influential citation
• Crop Improvement: Now and Beyond

  2021cites this paper
• Genes for Yield Stability in Tomatoes

  2021cites this paper
• Recognizing the hidden half in wheat: root system attributes associated with drought tolerance.

  2021cites this paper
• Gibberellin in tomato: metabolism, signaling and role in drought responses

  2021cites this paper
• Molecular Breeding for Improving Heat Stress Tolerance in Rice: Recent Progress and Future Perspectives

  2021cites this paper
• Wild coriander: an untapped genetic resource for future coriander breeding

  2021cites this paper
• Comparison of Genetic Variability and Trait Association for Yield Contributing Traits among F2 Populations Generated from Wild Introgression Lines of Rice

  2021cites this paper
• Physiological Characterization of Tomato Introgression Line IL5-4 That Increases Brix and Blossom-end Rot in Ripening Fruit

  2021cites this paper
• Genome-Wide Identification and Expression Profiling of Tomato Invertase Genes Indicate Their Response to Stress and Phytohormones

  2021cites this paper
• Sustainable Cultivation of GM Crops in the Age of Climate Change: A Global Perspective

  2021cites this paper
• Genetic diversity analysis and DNA fingerprinting of tomato breeding lines using SSR markers

  2021cites this paper
• Tapping Diversity From the Wild: From Sampling to Implementation

  2021cites this paper
• Sodium Sequestration Confers Salinity Tolerance in an Ancestral Wild Rice.

  2021cites this paper
• Yield dissection models to improve yield: a case study in tomato

  2021cites this paper
• The Wild Genetic Resources of Tomato: A Reservoir of Useful Genes for the Future

  2021cites this paper
• Exploring morpho-physiological profiles of a collection of tomato (Solanum lycopersicum) germplasm using multivariate statistics

  2020cites this paper
• Deep sampling and pooled amplicon sequencing reveals hidden genic variation in heterogeneous 2 rye accessions 3 4 5

  2020cites this paper
• Assessment of 16 Peanut (Arachis hypogaea L.) CSSLs Derived from an Interspecific Cross for Yield and Yield Component Traits: QTL Validation

  2020cites this paper
• Potential and limits of exploitation of crop wild relatives for pea, lentil, and chickpea improvement

  2020cites this paper
• Mutations in the tomato gibberellin receptors suppress xylem proliferation and reduce water loss under water-deficit conditions

  2020cites this paper
• Heat stress in cultivated plants: nature, impact, mechanisms, and mitigation strategies—a review

  2020cites this paper
• Crop wild relatives of the United States require urgent conservation action

  2020cites this paper
• Overexpression of BvHb2, a Class 2 Non-Symbiotic Hemoglobin from Sugar Beet, Confers Drought-Induced Withering Resistance and Alters Iron Content in Tomato

  2020cites this paper
• An overview of heat stress in tomato (Solanum lycopersicum L.)

  2020cites this paper
• Bioinformatic Extraction of Functional Genetic Diversity from Heterogeneous Germplasm Collections for Crop Improvement

  2020cites this paper
• Social and Environmental Impacts on Agricultural Development

  2020cites this paper
• Breeding Mechanisms for High Temperature Tolerance in Crop Plants

  2020cites this paper
• The Global Durum Wheat Panel (GDP): An International Platform to Identify and Exchange Beneficial Alleles

  2020cites this paper
• Tomato Phenotypic Diversity Determined by Combined Approaches of Conventional and High-Throughput Tomato Analyzer Phenotyping

  2020cites this paper
• Flowering Plants in the Anthropocene: A Political Agenda.

  2020cites this paper
• Evidence of the Role of QTL Epistatic Interactions in the Increase of Melon Fruit Flesh Content during Domestication

  2020cites this paper
• A Coordinated Suite of Wild-Introgression Lines in Indica and Japonica Elite Backgrounds

  2020cites this paper
• Back to the Wild: On a Quest for Donors Toward Salinity Tolerant Rice

  2020cites this paper
• Assessment of variation in the agronomic traits of wild cowpea (Vigna unguiculata (L.) Walp.) subspecies under a rainforest agro-ecology in Nigeria

  2020cites this paper
• Ocimum basilicum L. (Basil)

  2020cites this paper
• Genetic structure of a germplasm for hybrid breeding in rye (Secale cereale L.)

  2020cites this paper
• Dissecting the Genotypic and Environmental Factors Underpinning the Quantitative Trait Variation in a Set of Wild Tomato (Solanum habrochaites LA1777) Introgression Lines

  2020cites this paper
• Deep sampling and pooled amplicon sequencing reveals hidden genic variation in heterogeneous rye accessions

  2020cites this paper
• Evaluation of anatomical and physiological traits of Solanum pennellii Cor. associated with plant yield in tomato plants under water-limited conditions

  2020cites this paper
• Far‐red radiation stimulates dry mass partitioning to fruits by increasing fruit sink strength in tomato

  2020cites this paper
• Crop Wild Relatives: An Underutilized Genetic Resource for Improving Agricultural Productivity and Food Security

  2020cites this paper
• De Novo Domestication: An Alternative Route toward New Crops for the Future.

  2019cites this paper
• Genetic and physiological analysis of tomato (Solanum lycopersicum L.) adaption under heat and disease stress

  2019cites this paper
• Tomato Fruit Development and Metabolism

  2019cites this paper
• Resistance to greenbugs in the sorghum nested association mapping population

  2019cites this paper
• Candidate genes underlying the quantitative trait loci for root-knot nematode resistance in a Cucumis hystrix introgression line of cucumber based on population sequencing

  2019cites this paper
• Characterization of four favorable alleles conferring high thousand-kernel weight of common wheat ( Triticum aestivum L . ) in the Huang-huai wheat-growing region of China

  2019cites this paper
• Rice, Marker-Assisted Breeding, and Disease Resistance

  2019cites this paper
• Genomics-Assisted Breeding for Drought Tolerance in Cowpea

  2019cites this paper
• Exploring genetic diversity of tomato (Solanum lycopersicum L.) germplasm of genebank collection employing SSR and SCAR markers

  2019cites this paper
• Selected genome regions for fruit weight and shelf life in tomato RILs discernible by markers based on genomic sequence information

  2019cites this paper
• KROMOSOM TUMBUHAN SEBAGAI MARKA GENETIK

  2019cites this paper
• Conservation and Use of the North American Plant Cornucopia: The Way Forward

  2019cites this paper
• Temperature Extremes in Cotton Production and Mitigation Strategies

  2018cites this paper
• Phenotypic identity, similarity and stability for selection of tomatoes (Lycopersicon esculentum L.) cultivars in South-western Nigeria

  2018cites this paper
• Characterization of Nicotiana tabacum genotypes possessing deletion mutations that affect potyvirus resistance and the production of trichome exudates

  2018cites this paper
• Chapter 4 Temperature Extremes in Cotton Production and Mitigation Strategies

  2018cites this paper
• ASSESSING IMPACTS OF CROP-WILD INTROGRESSION IN LENTIL USING INTERSPECIFIC LENS SPECIES RECOMBINANT INBRED LINE POPULATIONS

  2018cites this paper
• Evaluation and consumer acceptance of five tomato (Lycopersicon esculentum Mill) cultivars in Northern Region of Ghana

  2018cites this paper
• Swarna × Oryza nivara introgression lines: a resource for seedling vigour traits in rice

  2018cites this paper
• Can genomics deliver climate-change ready crops?

  2018cites this paper
• Yield Traits and Associated Marker Segregation in Elite Introgression Lines Derived from O. sativa × O. nivara

  2018cites this paper
• Development of Genomic Resources for Rice Improvement

  2018cites this paper
• Genome-Wide Association Mapping of Major Root Length QTLs Under PEG Induced Water Stress in Wheat

  2018cites this paper