Immunopathogenic Mechanisms of HIV Infection

No abstract is available for this paper.

• Publication year

  1996

• Venue

  Annals of Internal Medicine

• Publication date

  1996-04-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.7326/0003-4819-124-7-199604010-00006PMID 2562941
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Histopathology of bone marrow in human immunodeficiency virus infXection

  2004cited by this paper
• HIV replication in IL-2-stimulated peripheral blood mononuclear cells is driven in an autocrine/paracrine manner by endogenous cytokines.

  1995cited by this paper
• Human immunodeficiency virus. Trapped but still dangerous.

  1995cited by this paper
• Follicular dendritic cells and human immunodeficiency virus infectivity

  1995cited by this paper
• Studies in subjects with long-term nonprogressive human immunodeficiency virus infection.

  1995influential reference
• New concepts in the immunopathogenesis of HIV infection.

  1995cited by this paper
• Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection.

  1995cited by this paper
• Trapped but still dangerous

  1995cited by this paper
• Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection

  1995cited by this paper
• Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection.

  1995cited by this paper
• Three populations of cells with dendritic morphology exist in peripheral blood, only one of which is infectable with human immunodeficiency virus type 1.

  1995influential reference
• Both a precursor and a mature population of dendritic cells can bind HIV. However, only the mature population that expresses CD80 can pass infection to unstimulated CD4+ T cells.

  1995cited by this paper
• Viral dynamics in human immunodeficiency virus type 1 infection

  1995cited by this paper
• Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

  1995cited by this paper
• Interleukin 1 induces expression of the human immunodeficiency virus alone and in synergy with interleukin 6 in chronically infected U1 cells: inhibition of inductive effects by the interleukin 1 receptor antagonist.

  1994cited by this paper
• Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals.

  1994cited by this paper
• Characterization of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte clones isolated during acute seroconversion: recognition of autologous virus sequences within a conserved immunodominant epitope

  1994influential reference
• Major expansion of CD8+ T cells with a predominant Vβ usage during the primary immune response to HIV

  1994cited by this paper
• Conjugates of dendritic cells and memory T lymphocytes from skin facilitate productive infection with HIV-1.

  1994cited by this paper
• Role of Lymphoid Organs in the Pathogenesis of Human Immunodeficiency Virus (HIV) Infection

  1994cited by this paper
• Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces

  1994cited by this paper
• Temporal association of cellular immune responses with the initial control of viremia in primary human immunodeficiency virus type 1 syndrome

  1994cited by this paper
• Human immunodeficiency virus infection of the human thymus and disruption of the thymic microenvironment in the SCID-hu mouse

  1993cited by this paper
• The SCID-hu mouse as a model for HIV-1 infection

  1993cited by this paper
• Multifactorial nature of human immunodeficiency virus disease: implications for therapy.

  1993influential reference
• An improved enrichment method for functionally competent, highly purified peripheral blood dendritic cells and its application to HIV‐infected blood samples

  1993cited by this paper
• Cytokine modulation of HIV expression.

  1993cited by this paper
• Massive covert infection of helper T lymphocytes and macrophages by HIV during the incubation period of AIDS

  1993cited by this paper
• Isolation and characterization of human peripheral blood dendritic cells.

  1993cited by this paper
• High levels of HIV-1 in plasma during all stages of infection determined by competitive PCR.

  1993cited by this paper
• Dendritic cells freshly isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium

  1993cited by this paper
• The immunopathogenesis of human immunodeficiency virus infection.

  1993cited by this paper
• HIV infection is active and progressive in lymphoid tissue during the clinically latent stage of disease

  1993influential reference
• HIV induces thymus depletion in vivo

  1993cited by this paper
• A novel cell-surface molecule expressed by human interdigitating reticulum cells, Langerhans cells, and activated lymphocytes is a new member of the Ig superfamily.

  1992cited by this paper
• CD34+ bone marrow cells are infected with HIV in a subset of seropositive individuals.

  1992cited by this paper
• During HIV‐1 infection most blood dendritic cells are not productively infected and can induce allogeneic CD4+ T cells clonal expansion

  1992cited by this paper
• Dendritic cells exposed to human immunodeficiency virus type-1 transmit a vigorous cytopathic infection to CD4+ T cells.

  1992cited by this paper
• Antigen-presentation by macrophages but not by dendritic cells in human immunodeficiency virus (HIV) infection.

  1992cited by this paper
• High titers of cytopathic virus in plasma of patients with symptomatic primary HIV-1 infection.

  1991influential reference
• NIH conference. Immunopathogenic mechanisms in human immunodeficiency virus (HIV) infection.

  1991cited by this paper
• The dendritic cell system and its role in immunogenicity.

  1991cited by this paper
• Long-term human immunodeficiency virus infection in asymptomatic homosexual and bisexual men with normal CD4+ lymphocyte counts: immunologic and virologic characteristics.

  1991cited by this paper
• Replication of human immunodeficiency virus type 1 in primary dendritic cell cultures.

  1991cited by this paper
• The human immunodeficiency virus.

  1991cited by this paper
• Primary HIV infection: host responses and intervention strategies.

  1991cited by this paper
• Immunopathogenic mechanisms in human immunodeficiency virus (HIV) infections.

  1991cited by this paper
• Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection.

  1991influential reference
• Lymphoid germinal centers are reservoirs of human immunodeficiency virus type 1 RNA.

  1991cited by this paper
• Defective clonogenic potential of CD8+ T lymphocytes in patients with AIDS. Expansion in vivo of a nonclonogenic CD3+CD8+DR+CD25- T cell population.

  1990cited by this paper
• Dendritic cell infection, depletion and dysfunction in HIV-infected individuals.

  1990cited by this paper
• Viral antigen stimulation of the production of human monokines capable of regulating HIV1 expression.

  1989cited by this paper
• Monokine regulation of human immunodeficiency virus-1 expression in a chronically infected human T cell clone.

  1989cited by this paper
• Tumor necrosis factor-alpha activation of the IL-2 receptor-alpha gene involves the induction of kappa B-specific DNA binding proteins.

  1989cited by this paper
• Purified blood monocytes from HIV 1-infected patients induce high levels of TNFα and IL-1

  1989cited by this paper
• Tumor necrosis factor enhances replication of human immunodeficiency virus (HIV) in vitro.

  1989cited by this paper
• Tumor necrosis factor alpha and interleukin 1 stimulate the human immunodeficiency virus enhancer by activation of the nuclear factor kappa B.

  1989cited by this paper
• Productive dual infection of human CD4+ T lymphocytes by HIV-1 and HHV-6

  1989cited by this paper
• Tumor necrosis factor alpha induces expression of human immunodeficiency virus in a chronically infected T-cell clone.

  1989cited by this paper
• The thymus in acquired immune deficiency syndrome. Comparison with other types of immunodeficiency diseases, and presence of components of human immunodeficiency virus type 1.

  1989cited by this paper
• The herpes simplex virus immediate-early protein, ICP4, is required to potentiate replication of human immunodeficiency virus in CD4+ lymphocytes

  1989cited by this paper
• Hepatitis B virus X gene can transactivate heterologous viral sequences.

  1989cited by this paper
• Tumor necrosis factor alpha induces proteins that bind specifically to kappa B-like enhancer elements and regulate interleukin 2 receptor alpha-chain gene expression in primary human T lymphocytes.

  1989cited by this paper
• Transactivation of human immunodeficiency virus promoter by human herpesvirus 6

  1989cited by this paper
• The SCID-hu mouse: murine model for the analysis of human hematolymphoid differentiation and function.

  1988cited by this paper
• Replication and pathogenesis of the AIDS virus.

  1988cited by this paper
• Nef protein of HIV-1 is a transcriptional repressor of HIV-1 LTR.

  1988cited by this paper
• Infection and replication of HIV-1 in purified progenitor cells of normal human bone marrow

  1988cited by this paper
• Alternative mechanisms for activation of human immunodeficiency virus enhancer in T cells.

  1988cited by this paper
• An Epstein-Barr virus immediate-early gene product trans-activates gene expression from the human immunodeficiency virus long terminal repeat.

  1988cited by this paper
• Activation of the human immunodeficiency virus long terminal repeat by herpes simplex virus type 1 is associated with induction of a nuclear factor that binds to the NF-kappa B/core enhancer sequence

  1988cited by this paper
• AIDS as immune system activation: a model for pathogenesis.

  1988cited by this paper
• Efficient isolation and propagation of human immunodeficiency virus on recombinant colony-stimulating factor 1-treated monocytes

  1988cited by this paper
• Trans-activation of the human immunodeficiency virus long terminal repeat by the hepatitis B virus X protein.

  1988cited by this paper
• The role of cachectin/TNF in endotoxic shock and cachexia.

  1988cited by this paper
• Cytokines alter production of HIV-1 from primary mononuclear phagocytes.

  1988cited by this paper
• The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex.

  1988cited by this paper
• Activation of human immunodeficiency virus type 1 by DNA damage in human cells

  1988cited by this paper
• HIV and HCMV coinfect brain cells in patients with AIDS.

  1988cited by this paper
• HIV-1 production from infected peripheral blood T cells after HTLV-I induced mitogenic stimulation.

  1988cited by this paper
• Elevated levels of circulating cachectin/tumor necrosis factor in patients with acquired immunodeficiency syndrome.

  1988cited by this paper
• Characterization of a promonocyte clone chronically infected with HIV and inducible by 13-phorbol-12-myristate acetate.

  1988cited by this paper
• Heat-shock induction of the human immunodeficiency virus long terminal repeat.

  1988cited by this paper
• The human immunodeficiency virus: infectivity and mechanisms of pathogenesis.

  1988cited by this paper
• Identification and purification of a human immunoglobulin-enhancer-binding protein (NF-kappa B) that activates transcription from a human immunodeficiency virus type 1 promoter in vitro.

  1988cited by this paper
• Activation of the human immunodeficiency virus by herpes simplex virus type 1

  1987cited by this paper
• Activation of the HIV-1 LTR by T cell mitogens and the trans-activator protein of HTLV-I.

  1987cited by this paper
• HTLV-III large envelope protein (gp120) suppresses PHA-induced lymphocyte blastogenesis.

  1987cited by this paper
• Effect of phorbol esters on down-regulation and redistribution of cell surface receptors for tumor necrosis factor-alpha.

  1987cited by this paper
• Activation of human immunodeficiency virus by herpesvirus infection: identification of a region within the long terminal repeat that responds to a trans-acting factor encoded by herpes simplex virus 1.

  1987cited by this paper
• In vitro activation of the HIV‐1 enhancer in extracts from cells treated with a phorbol ester tumor promoter.

  1987cited by this paper
• Human immunodeficiency virus long terminal repeat responds to T-cell activation signals.

  1987cited by this paper
• The effects of human immunodeficiency virus recombinant envelope glycoprotein on immune cell functions in vitro.

  1987cited by this paper
• Cytokine-induced expression of HIV-1 in a chronically infected promonocyte cell line.

  1987cited by this paper
• Immediate-early gene region of human cytomegalovirus trans-activates the promoter of human immunodeficiency virus.

  1987cited by this paper
• Herpes simplex virus type-1 can reactivate transcription of latent human immunodeficiency virus

  1987cited by this paper
• An inducible transcription factor activates expression of human immunodeficiency virus in T cells

  1987cited by this paper
• Suppression of in vitro haematopoiesis following human immunodeficiency virus infection

  1987cited by this paper
• Amplification of HTLV-III/LAV infection by antigen-induced activation of T cells and direct suppression by virus of lymphocyte blastogenic responses.

  1987cited by this paper
• AIDS: immunopathogenic mechanisms and research strategies.

  1987cited by this paper

• Prevalence of late HIV diagnosis and its impact on mortality: A comprehensive systematic review and meta‐analysis

  2025cites this paper
• Skin Cancers in People Living with Human Immunodeficiency Virus (HIV) Infection

  2025cites this paper
• Molecular mechanisms of co-infections

  2025cites this paper
• Inclusion of a retroviral protease enhances the immunogenicity of VLP-forming mRNA vaccines against HIV-1 or SARS-CoV-2 in mice

  2025cites this paper
• The Impact of Yogurt, Legumes, and Coffee on Health Outcomes in HIV: You are What You Eat?

  2025cites this paper
• Considering the effects of pair formation dynamics on mpox and HIV co-infection in the gbMSM community

  2025cites this paper
• Multiway Sequential Cellular Automata

  2025cites this paper
• Psychosocial Determinants of Antiretroviral Treatment Adherence among Black Mothers with HIV

  2025cites this paper
• HIV disease progression among heterosexually-infected individuals before the introduction of universal ART in China: A linear mixed-effects model.

  2024cites this paper
• Survival Analysis of Antiretroviral Treatment for PLWH in Sichuan Province, China, 2003-2022: A Large Retrospective Cohort Study

  2024cites this paper
• Machine learning approaches in designing anti-HIV nitroimidazoles: 2D/3D QSAR, kNN-MFA, docking, dynamics, PCA analysis and MMGBSA studies

  2024cites this paper
• Nicotine is an Immunosuppressant: Implications for Women's Health and Disease.

  2024cites this paper
• The Mathematics of Cellular Automata

  2024cites this paper
• Reaction-diffusion model of HIV infection of two target cells under optimal control strategy

  2024cites this paper
• Assessing the reliability of the CD4 depletion model in the presence of Ending the HIV Epidemic initiatives

  2023cites this paper
• Immediate and long-term outcomes after treat-all among people living with HIV in China: an interrupted time series analysis

  2023cites this paper
• Phytochemicals and HIV Suppression: A Systematic Review

  2023cites this paper
• Alteration of Gut microbiota during HIV infection

  2023cites this paper
• Current drugs for HIV-1: from challenges to potential in HIV/AIDS

  2023cites this paper
• Possibility of Decreasing Incidence of Human Immunodeficiency Virus Infection in Korea

  2023cites this paper
• Лауреаты Нобелевской премии по физиологии или медицине 2023 года — Каталин Карико и Дрю Вайсман, "Природа"

  2023cites this paper
• T‐lymphocyte subtyping: an early warning and a potential prognostic indicator of active cytomegalovirus infection in patients with sepsis

  2022cites this paper
• Asymptomatic HIV-Infected Patients Present Blood Parameters Changed, According to Use of Therapy and the CD4+ T Cells Count

  2022cites this paper
• Infección por el virus de la inmunodeficiencia humana

  2022cites this paper
• A study of ocular manifestations in HIV positive patients

  2022cites this paper
• T-Cell Receptor Repertoire Sequencing and Its Applications: Focus on Infectious Diseases and Cancer

  2022influential citation
• Targeting NK Cells for HIV-1 Treatment and Reservoir Clearance

  2022cites this paper
• Bone, Brain, Heart study protocol: A resilient nested, tripartite prospective cohort study of the role of estrogen depletion on HIV pathology

  2022cites this paper
• Recent Trends in Adult and Pediatric Antiretroviral Therapy Monitoring and Failure

  2022cites this paper
• The association between comorbidities and coronavirus disease 2019 hospitalization among people with HIV differs by age

  2022cites this paper
• Cardiovascular Implications of Immune Disorders in Women

  2022cites this paper
• T-Lymphocyte Subtyping: A Potential Diagnostic and Prognostic Indicator of Cytomegalovirus Infection in Sepsis Patients

  2021cites this paper
• A fractional calculus model for HIV dynamics: real data, parameter estimation and computational strategies

  2021cites this paper
• Co-receptor signaling in the pathogenesis of neuroHIV

  2021cites this paper
• HIV/AIDS Global Epidemic

  2021cites this paper
• Peripheral Auditory Function in Young HIV-Positive Adults With Clinically Normal Hearing

  2021cites this paper
• Epidemiological and spatiotemporal analyses of HIV/AIDS prevalence among older adults in Sichuan, China between 2008 and 2019: a population-based study.

  2021cites this paper
• Periodontal Health and Systemic Conditions

  2020cites this paper
• Assessing the impact of HIV treatment interruptions using Stochastic Cellular Automata.

  2020cites this paper
• C-Reactive Protein in Cardiovascular Disease

  2020cites this paper
• HIV gp120 Induces the Release of Proinflammatory, Angiogenic, and Lymphangiogenic Factors from Human Lung Mast Cells

  2020cites this paper
• Estimating the probability of diagnosis within one year of HIV acquisition.

  2020cites this paper
• Global Burden of HIV/AIDS

  2020cites this paper
• HIV/AIDS

  2020cites this paper
• Role of Divalent Cations in HIV-1 Replication and Pathogenicity

  2020cites this paper
• Investigation of HIV-1 Variants with Broader Tropism than Wild-type Virus

  2019cites this paper
• Clinical features of acute human immunodeficiency virus infection in Taiwan: A multicenter study.

  2019cites this paper
• Modeling HIV Infection

  2019cites this paper
• Pulmonary Hypertension in HIV.

  2019cites this paper
• Towards a Phylogenetic Measure to Quantify HIV Incidence

  2019cites this paper
• Germinal centers B-cell reaction and T follicular helper cells in response to HIV-1 infection.

  2019cites this paper
• HIV transmission between spouses living in Lu'an city, Anhui province, China: a longitudinal study

  2019cites this paper
• Efficient Computational Models for assessment of Spatial Infection Features

  2019cites this paper
• Interferon-inducible TRIM22 contributes to maintenance of HIV-1 proviral latency in T cell lines.

  2019cites this paper
• Effects of Isolation of HIV-1 Envelope Clones from Patient 2044 on Tropism, Co-receptor Use, and Antibody Sensitivity

  2019cites this paper
• Epidemiological Features and Risk Factors for Acquiring Hepatitis B, Hepatitis C, and Syphilis in HIV-Infected Patients in Shaanxi Province, Northwest China

  2019cites this paper
• Overcoming diffusion-limited trapping in nanoaperture tweezers using opto-thermal-induced flow.

  2019cites this paper
• Partner HIV serostatus impacts viral load, genital HIV shedding and immune activation in HIV-infected individuals.

  2019cites this paper
• Bistable dynamics and Hopf bifurcation in a refined model of early stage HIV infection

  2019cites this paper
• Bibliography

  2019cites this paper
• Viral, Protozoan, and Related Intracranial Infections

  2018cites this paper
• Intranasal Immunization with DnaK Protein Induces Protective Mucosal Immunity against Tuberculosis in CD4-Depleted Mice

  2018cites this paper
• Next-generation in situ hybridization approaches to define and quantify HIV and SIV reservoirs in tissue microenvironments

  2018cites this paper
• Mathematical Analysis of Viral Replication Dynamics and Antiviral Treatment Strategies: From Basic Models to Age-Based Multi-Scale Modeling

  2018cites this paper
• Impact of gender, sexual orientation and socio-economic factors on HIV treatment outcomes in the UK

  2018cites this paper
• Modelling coupled within host and population dynamics of $$R_5$$R5 and $$X_4$$X4 HIV infection

  2018cites this paper
• 3 Human Immunodeficiency Virus Transmission Goselle

  2018cites this paper
• Sex Differences in the Kinetics of Immune Reconstitution under Antiretroviral Therapy

  2018cites this paper
• Reduction in HIV community viral loads following the implementation of a “Treatment as Prevention” strategy over 2 years at a population-level among men who have sex with men in Hangzhou, China

  2018cites this paper
• Duration of Human Immunodeficiency Virus Infection at Diagnosis among New Human Immunodeficiency Virus Cases in Dehong, Yunnan, China, 2008–2015

  2018cites this paper
• Comparison of antiviral resistance across acute and chronic viral infections

  2018cites this paper
• Enhanced sensitivity in THz plasmonic sensors with silver nanowires

  2018cites this paper
• Mechanisms of recognition of HIV-infected cells by CD8+ T cells that mediate effective antiviral responses

  2017cites this paper
• Microfluidic-based high-throughput optical trapping of nanoparticles.

  2017cites this paper
• HIV-Associated Pulmonary Hypertension: A Global Perspective

  2017cites this paper
• Personalized life expectancy and treatment benefit index of antiretroviral therapy

  2017cites this paper
• Studies on immune exhaustion and senescence of certain CD8+ T-CELL phenotypes in HIV-TB co-infected individuals / Alireza Saeidi

  2017cites this paper
• Estimated HIV Incidence in the United States, 2003–2010

  2017cites this paper
• Couverture vaccinale des patients adultes infectés par le VIH suivis au CHU de Bordeaux sur le site de Saint-André

  2017cites this paper
• 11 – HIV and HIV-associated Disorders

  2017cites this paper
• Using CD4 Data to Estimate HIV Incidence, Prevalence, and Percent of Undiagnosed Infections in the United States

  2017cites this paper
• Continuum of Care Among People Living with Perinatally Acquired HIV Infection in New York City, 2014

  2016cites this paper
• Effect of Wuchereria bancrofti infection on HIV incidence in southwest Tanzania: a prospective cohort study.

  2016cites this paper
• Role of high-sensitivity C-reactive protein measurements in HIV patients

  2016cites this paper
• Immunological Profiles in HIV Positive Patients with or without Opportunistic Infections and the Influence of Highly Active Antiretroviral Therapy: A Systematic Review and Update

  2016influential citation
• Interactive Data Visualization for HIV Cohorts: Leveraging Data Exchange Standards to Share and Reuse Research Tools

  2016cites this paper
• Modelling coupled within host and population dynamics of R5 and X4 HIV infection

  2016cites this paper
• Brief Report: Relationship Among Viral Load Outcomes in HIV Treatment Interruption Trials

  2016cites this paper
• Rôle de la conformation des glycoprotéines de l’enveloppe du VIH-1 dans la réponse cytotoxique cellulaire dépendante des anticorps et impact des protéines virales Nef et Vpu

  2016cites this paper
• Human Herpesviruses as Copathogens of HIV Infection, Their Role in HIV Transmission, and Disease Progression

  2016cites this paper
• HIV Infection: Epidemiology, Natural History and Diagnosis

  2016cites this paper
• Mathematical analysis and dynamic active subspaces for a long term model of HIV.

  2016cites this paper
• Overview of Infections in the Immunocompromised Host

  2016cites this paper
• Prevalent neuropathy in a cohort of HIV-infected Kenyan sex workers using antiretroviral drugs

  2016cites this paper
• EPICE-HIV: An Epidemiologic Cost-Effectiveness Model for HIV Treatment

  2016cites this paper
• The Impact of HIV and Antiretroviral Therapy on the Cardiovascular System of HIV-infected Children

  2016cites this paper
• Adaptive Evolution of the SIV Envelope Protein During Early SIV Infection

  2016cites this paper
• Human Neural Progenitor Cells are Productively Infected by R5-tropic HIV-1: Opiate Interactions on Infection and Function Involve Cdk5 Signaling

  2016cites this paper
• Works Title Ectopic expression of anti-HIV-1 shRNAs protects CD 8 ( + ) T cells modified with CD 4 ζ CAR from HIV-1 infection and alleviates impairment of cell proliferation

  2015cites this paper
• Antiretroviral Therapy: New Mechanistic and Therapeutic Insights for HIV Single-Entity and Combination Drug Products.

  2015cites this paper