Characterization of α2-adrenoceptors which increase potassium conductance in rat locus coeruleus neurones

No abstract is available for this paper.

• Publication year

  1985

• Venue

  Neuroscience

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1016/0306-4522(85)90166-6
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

  1997cited by this paper
• Catecholamine inhibition of calcium action potentials in rat locus coeruleus neurones.

  1985cited by this paper
• Membrane properties of rat locus coeruleus neurones.

  1984cited by this paper
• The actions of noradrenaline on neurones of the rat substantia gelatinosa in vitro.

  1984cited by this paper
• Studies on RX 781094: a selective, potent and specific antagonist of α2‐adrenoceptors

  1983cited by this paper
• Noradrenaline‐mediated synaptic inhibition in rat locus coeruleus neurones.

  1983cited by this paper
• How do opiates inhibit neurotransmitter release

  1983cited by this paper
• [3H]RX 781094: A new antagonist ligand labels α2-adrenoceptors in the rat brain cortex

  1983cited by this paper
• The calcium‐activated potassium conductance in guinea‐pig myenteric neurones

  1982cited by this paper
• alpha 2-adrenoceptor-mediated hyperpolarization of locus coeruleus neurons: intracellular studies in vivo.

  1982cited by this paper
• Relative potencies of alpha-1 and alpha-2 antagonists in the locus ceruleus, dorsal raphe and dorsal lateral geniculate nuclei: an electrophysiological study.

  1982cited by this paper
• Pharmacological characterization of presynaptic alpha-adrenoceptors modulating [3H]noradrenaline and [3H]5-hydroxytryptamine release from slices of the hippocampus of the rat.

  1982cited by this paper
• CLONIDINE ACTIVATES MEMBRANE POTASSIUM CONDUCTANCE IN MYENTERIC NEURONES

  1981cited by this paper
• Noradrenergic alpha 1 and alpha 2 receptors: light microscopic autoradiographic localization.

  1980cited by this paper
• Inhibition of neuronal uptake reduces the presynaptic effects of clonidine but not of alpha-methylnoradrenaline on the stimulation-evoked release of 3H-noradrenaline from rat occipital cortex slices.

  1980cited by this paper
• HYPERPOLARIZING ‘α2’‐ADRENOCEPTORS IN RAT SYMPATHETIC GANGLIA

  1979cited by this paper
• Catecholamine receptors on locus coeruleus neurons: pharmacological characterization.

  1977cited by this paper
• Ion movements in junctional transmission.

  1967cited by this paper

• Chronic stress impairs autoinhibition in neurons of the locus coeruleus to increase asparagine endopeptidase activity

  2025cites this paper
• Functional characterization of the α1-adrenoceptor in adult male rat locus coeruleus neurons ex vivo

  2025cites this paper
• The Locus Coeruleus—Noradrenergic System in the Healthy and Diseased Brain: A Narrative Review

  2025cites this paper
• Circuit-selective pharmacological targeting of prefrontal cortex-projecting locus coeruleus neurons drives antinociception.

  2025cites this paper
• The Na+ leak channel NALCN controls spontaneous activity and mediates synaptic modulation by α2-adrenergic receptors in auditory neurons

  2024cites this paper
• LC-derived excitatory synaptic transmission to dorsal raphe serotonin neurons is inhibited by activation of alpha2-adrenergic receptors

  2024cites this paper
• Cellular composition and circuit organization of the locus coeruleus of adult mice

  2023cites this paper
• Alpha2 Adrenergic Modulation of Spike-Wave Epilepsy: Experimental Study of Pro-Epileptic and Sedative Effects of Dexmedetomidine

  2023cites this paper
• The Na+ leak channel NALCN controls spontaneous activity and mediates synaptic modulation by α2-adrenergic receptors in auditory neurons

  2023cites this paper
• Inhibition of noradrenaline-dependent synaptic transmission in the dorsal raphe nucleus by alpha2-adrenergic receptors

  2023cites this paper
• Abnormal Automatic Movements after Dexmedetomidine Administration in a Newborn: A Case Report

  2022cites this paper
• Dexmedetomidine Diminishes, but Does Not Prevent, Developmental Effects of Sevoflurane in Neonatal Rats

  2022cites this paper
• Noradrenergic cross-modular reciprocal inhibition within the locus coeruleus

  2022cites this paper
• The role of glutamate transporter-1 in firing activity of locus coeruleus neurons and nociception in rats

  2021cites this paper
• Alpha adrenergic receptors have role in the inhibitory effect of electrical low frequency stimulation on epileptiform activity in rats

  2021cites this paper
• Role of central serotonin and noradrenaline interactions in the antidepressants' action: Electrophysiological and neurochemical evidence.

  2021cites this paper
• Systemic Effects and Clinical Application of Medetomidine in Animals: A Review

  2020cites this paper
• Ethanol abolishes vigilance-dependent astroglia network activation in mice by inhibiting norepinephrine release

  2020cites this paper
• The Octopaminergic Modulatory Circuitry of the Drosophila Larval Mushroom Body Calyx

  2019cites this paper
• Study of effects of ifenprodil in patients with methamphetamine dependence: Protocol for an exploratory, randomized, double‐blind, placebo‐controlled trial

  2019cites this paper
• Amyloid beta peptides, locus coeruleus-norepinephrine system and dense core vesicles.

  2019cites this paper
• Functional Organization of the Sympathetic Pathways Controlling the Pupil: Light-Inhibited and Light-Stimulated Pathways

  2018cites this paper
• G Protein-Gated Potassium Channels: A Link to Drug Addiction.

  2017cites this paper
• The impact of psychostimulant administration during development on adult brain functions controlling motivation, impulsivity and cognition.

  2016cites this paper
• Lactate in Sevofl urane Anesthetized Horses

  2015cites this paper
• Effects of elevated body temperature on structure and function of cerebrum and cerebellum of Wistar male albino rats.

  2015cites this paper
• GABAB receptor‐mediated tonic inhibition regulates the spontaneous firing of locus coeruleus neurons in developing rats and in citalopram‐treated rats

  2015cites this paper
• Simplified models of pacemaker spiking in raphe and locus coeruleus neurons

  2015cites this paper
• Energy Imbalance and Physiological Changes During Detomidine Hydrochloride Constant Rate Infusion in Standing Horses

  2015cites this paper
• Dysfunctional Inhibitory Mechanisms in Locus Coeruleus Neurons of the Wistar Kyoto Rat

  2015cites this paper
• Altered neuronal activity and differential sensitivity to acute antidepressants of locus coeruleus and dorsal raphe nucleus in Wistar Kyoto rats: a comparative study with Sprague Dawley and Wistar rats.

  2014cites this paper
• Influence of romifidine and detomidine on the induction of anesthesia and recovery from total intravenous anesthesia in horses De invloed van romifidine en detomidine op de inductie en recovery bij paarden in combinatie met totale intraveneuze anesthesie

  2014cites this paper
• ATP in the locus coeruleus as a modulator of cardiorespiratory control in unanaesthetized male rats

  2014cites this paper
• Clonidine in pediatric anesthesia : aspects on population pharmacokinetics, nasal administration and safety

  2014cites this paper
• Neurochemical and electrical modulation of the locus coeruleus: contribution to CO2drive to breathe

  2014cites this paper
• Mood Induced Changes in Global or Local Processing of Information Explained by Locus Coeruleus Norepinephrine Patterns of Activity

  2014cites this paper
• Structure-Affinity Relationship Study of Novel Imidazoline Ligands at Imidazoline Binding Sites and α-Adrenoceptors

  2014cites this paper
• Persistent α1-adrenergic receptor function in the nucleus locus coeruleus causes hyperexcitability in AD/HD model rats.

  2014cites this paper
• Sustained impairment of α2A-adrenergic autoreceptor signaling mediates neurochemical and behavioral sensitization to amphetamine.

  2013cites this paper
• L-DOPA modifies the antidepressant-like effects of reboxetine and fluoxetine in rats.

  2013cites this paper
• Effects of Angiotensin Receptor Blocker and Calcium Channel Blocker on Experimental Abdominal Aortic Aneurysms in a Hamster Model

  2012cites this paper
• Physiology of quantal norepinephrine release from somatodendritic sites of neurons in locus coeruleus

  2012cites this paper
• Morphine Decreases Enteric Neuron Excitability via Inhibition of Sodium Channels

  2012cites this paper
• Effects of detomidine constant rate infusion on blood glucose and lactate in sevoflurane anesthetized horses.

  2012cites this paper
• Modifications à long terme des systèmes noradrénergique et sérotoninergique dans la sensibilisation comportementale induite par l'éthanol et l'amphétamine

  2012cites this paper
• Modulation of physiological reflexes by pain: role of the locus coeruleus

  2012cites this paper
• Extrasynaptic exocytosis and its mechanisms: a source of molecules mediating volume transmission in the nervous system

  2012cites this paper
• Regulation of central noradrenergic activity by 5-HT(3) receptors located in the locus coeruleus of the rat.

  2012cites this paper
• Eff ects of Detomidine Constant Rate Infusion on Blood Glucose and Lactate in Sevofl urane Anesthetized Horses

  2012cites this paper
• Dopamine depresses melanin concentrating hormone neuronal activity through multiple effects on α2-noradrenergic, D1 and D2-like dopaminergic receptors.

  2011cites this paper
• INHIBITORY SYNAPTIC TRANSMISSION IN EARLY AUDITORY PROCESSING

  2011cites this paper
• Noradrenaline enhances signal-to-noise ratio of inhibitory inputs in the dorsal cochlear nucleus.

  2011cites this paper
• Spontaneous spiking and synaptic depression underlie noradrenergic control of feed-forward inhibition.

  2011cites this paper
• Dexmedetomidine: pediatric pharmacology, clinical uses and safety

  2011cites this paper
• UNIVERSIDADE FEDERAL DO RIO GRANDE DO SUL FACULDADE DE VETERINÁRIA PROGRAMA DE PÓS-GRADUAÇÃO EM MEDICINA ANIMAL: EQUINOS

  2011cites this paper
• Methylphenidate enhances inhibitory synaptic transmission by increasing the content of norepinephrine in the locus coeruleus of juvenile rats.

  2010cites this paper
• Pacemaking in mouse locus coeruleus neurons: electrophysiological properties, role of mitochondria and development

  2010cites this paper
• Pacemaker currents in mouse locus coeruleus neurons.

  2010cites this paper
• The Involvement of Hypothalamic Sleep Pathways in General Anesthesia: Testing the Hypothesis Using the GABAA Receptor β3N265M Knock-In Mouse

  2009cites this paper
• Comparison of the effects of the alpha-2 agonists detomidine, romifidine and xylazine on nociceptive withdrawal reflex and temporal summation in horses.

  2009cites this paper
• Functional Neuroanatomy of the Noradrenergic Locus Coeruleus: Its Roles in the Regulation of Arousal and Autonomic Function Part I: Principles of Functional Organisation

  2008cites this paper
• 5-HT1A receptor expression : Studies in postmortem tissue and characterisation of a model system.

  2008cites this paper
• İntravenöz Deksmedetomidin Premedikasyonunun Bupivakain ile Uygulanan Spinal Anestezide Duyusal Blok Süresine Etkisi

  2008cites this paper
• Functional Neuroanatomy of the Noradrenergic Locus Coeruleus: Its Roles in the Regulation of Arousal and Autonomic Function Part II: Physiological and Pharmacological Manipulations and Pathological Alterations of Locus Coeruleus Activity in Humans

  2008cites this paper
• Chronic cold exposure increases RGS7 expression and decreases α2‐autoreceptor‐mediated inhibition of noradrenergic locus coeruleus neurons

  2008cites this paper
• Adrenergic drugs modify the level of noradrenaline in the insular cortex and alter extinction of conditioned taste aversion in rats.

  2007cites this paper
• Noradrenergic neuromodulation of human attention for emotional and neutral stimuli

  2007cites this paper
• The Mechanistic Relationship between NREM Sleep and Anesthesia

  2006cites this paper
• The influence of the time course of inflammation and spinalization on the antinociceptive activity of the alpha2-adrenoceptor agonist medetomidine.

  2006cites this paper
• Methylphenidate Increases Cortical Excitability via Activation of Alpha-2 Noradrenergic Receptors

  2006cites this paper
• Orexin neurons are directly and indirectly regulated by catecholamines in a complex manner.

  2006cites this paper
• Adaptive gain and the role of the locus coeruleus–norepinephrine system in optimal performance

  2005cites this paper
• Medetomidine and dexmedetomidine: a review of cardiovascular effects and antinociceptive properties in the dog.

  2005cites this paper
• Does modafinil activate the locus coeruleus in man? Comparison of modafinil and clonidine on arousal and autonomic functions in human volunteers

  2005cites this paper
• One hundred years of adrenaline: the discovery of autoreceptors

  2005cites this paper
• 3,4-Dihydroxyphenylacetic acid (DOPAC) as an index of noradrenaline turnover: Effects of hydergine® and vincamine

  2005cites this paper
• The Effects of Anesthetics and Ethanol on α2 Adrenoceptor Subtypes Expressed with G Protein-Coupled Inwardly Rectifying Potassium Channels in Xenopus Oocytes

  2005cites this paper
• An integrative theory of locus coeruleus-norepinephrine function: adaptive gain and optimal performance.

  2005cites this paper
• α2-Adrenoceptor involvement in the in vitro inhibitory effect of citalopram on a subpopulation of rat locus coeruleus neurons

  2005cites this paper
• The role of the locus coeruleus in mediating the attentional blink: a neurocomputational theory.

  2005cites this paper
• Comparative study of the effects of desipramine and reboxetine on locus coeruleus neurons in rat brain slices.

  2004cites this paper
• Effects of inactivation and stimulation of locus coeruleus on respiratory activity of neonatal rat.

  2004cites this paper
• Effects of milnacipran on the inhibitory postsynaptic potential in neurons of the rat locus coeruleus.

  2004cites this paper
• Some in vivo electrophysiological properties of locus coeruleus neurones in fetal rats

  2004cites this paper
• Corticotropin-Releasing Hormone Directly Activates Noradrenergic Neurons of the Locus Ceruleus Recorded In Vitro

  2004cites this paper
• CHAPTER 11 – Locus Coeruleus, A5 and A7 Noradrenergic Cell Groups

  2004cites this paper
• Effect of K+ channel blockers on the α2-adrenoceptor-coupled regulation of electrically evoked noradrenaline release in hippocampus

  2004cites this paper
• Chronic Exposure to Cold Stress Alters Electrophysiological Properties of Locus Coeruleus Neurons Recorded In Vitro

  2003cites this paper
• Alpha 2 adrenergic receptors on GABAergic, putative sleep‐promoting basal forebrain neurons

  2003cites this paper
• A Model for the Cellular Mechanisms of Morphine Tolerance and Dependence

  2003cites this paper
• Effects of the α2-adrenoreceptor antagonist dexefaroxan on neurogenesis in the olfactory bulb of the adult rat in vivo: selective protection against neuronal death

  2003cites this paper
• α2A and α2C‐adrenoceptor regulation in the brain: α2A changes persist after chronic stress

  2003cites this paper
• The α2-Adrenoceptor Agonist Dexmedetomidine Converges on an Endogenous Sleep-promoting Pathway to Exert Its Sedative Effects

  2003cites this paper
• Electrophysiological characterization of chronic stress-induced sensitization of noradrenergic neurons of the locus coeruleus

  2002influential citation
• Simplified dynamics in a model of noradrenergic modulation of cognitive performance

  2002cites this paper
• Involvement of central KATP channels in the gastric antisecretory action of α2-adrenoceptor agonists and β-endorphin in rats

  2002cites this paper
• Physiology of Sleep and Wakefulness as it Relates to the Physiology of Epilepsy

  2002cites this paper
• Chronic substance P (NK1) receptor antagonist and conventional antidepressant treatment increases burst firing of monoamine neurones in the locus coeruleus.

  2002cites this paper
• Expression of mRNA and functional alpha1‐adrenoceptors that suppress the GIRK conductance in adult rat locus coeruleus neurons

  2002cites this paper
• SEMMELWEIS UNIVERSITY SCHOOL OF PH.D. STUDIES – PHARMACOLOGICAL SCIENCES Ph.D. thesis The role of the central nervous system in the regulation of gastric acid secretion and mucosal protection – involvement of central α2-adrenergic and opioid-receptors

  2002cites this paper