Coordination of FOXA 2 and SIRT 6 suppresses the hepatocellular carcinoma progression through ZEB 2 inhibition

No abstract is available for this paper.

• Publication year

  2018

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Not labeled

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Transcriptomic and CRISPR/Cas9 technologies reveal FOXA2 as a tumor suppressor gene in pancreatic cancer.

  2016cited by this paper
• Upregulation of SIRT6 predicts poor prognosis and promotes metastasis of non-small cell lung cancer via the ERK1/2/MMP9 pathway

  2016cited by this paper
• Hepatocellular carcinoma: Exploring the impact of ethnicity on molecular biology.

  2016cited by this paper
• Downregulation of ZEB2-AS1 decreased tumor growth and metastasis in hepatocellular carcinoma

  2016cited by this paper
• Liquid Biopsy of Hepatocellular Carcinoma: Circulating Tumor-Derived Biomarkers

  2016cited by this paper
• FOXA2 attenuates the epithelial to mesenchymal transition by regulating the transcription of E-cadherin and ZEB2 in human breast cancer.

  2015cited by this paper
• Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis

  2015cited by this paper
• Decreased expression of SIRT6 promotes tumor cell growth correlates closely with poor prognosis of ovarian cancer.

  2014cited by this paper
• FOXA2 suppresses the metastasis of hepatocellular carcinoma partially through matrix metalloproteinase-9 inhibition.

  2014cited by this paper
• SIRT1 Mediates FOXA2 Breakdown by Deacetylation in a Nutrient-Dependent Manner

  2014cited by this paper
• Sirt6 suppresses hepatocellular carcinoma cell growth via inhibiting the extracellular signal‑regulated kinase signaling pathway.

  2014influential reference
• Sirtuin‐6–dependent genetic and epigenetic alterations are associated with poor clinical outcome in hepatocellular carcinoma patients

  2013cited by this paper
• SIRT6 modulates paclitaxel and epirubicin resistance and survival in breast cancer.

  2013cited by this paper
• Altered expression of SIRT gene family in head and neck squamous cell carcinoma

  2013cited by this paper
• Emerging roles of SIRT6 on telomere maintenance, DNA repair, metabolism and mammalian aging

  2012cited by this paper
• The NAD+-dependent Histone Deacetylase SIRT6 Promotes Cytokine Production and Migration in Pancreatic Cancer Cells by Regulating Ca2+ Responses*

  2012cited by this paper
• The histone deacetylase SIRT6 is a tumor suppressor that controls cancer metabolism.

  2012cited by this paper
• Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells.

  2011cited by this paper
• Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer.

  2010cited by this paper
• The histone deacetylase Sirt6 regulates glucose homeostasis via Hif1alpha.

  2010cited by this paper
• Epithelial-Mesenchymal Transition in Cancer: Parallels Between Normal Development and Tumor Progression

  2010cited by this paper
• Hepatocellular Carcinoma: Epidemiology and Molecular Carcinogenesis

  2009cited by this paper
• Epithelial-mesenchymal transition in development and cancer.

  2009cited by this paper
• The Foxa family of transcription factors in development and metabolism

  2006cited by this paper
• Foxa2 integrates the transcriptional response of the hepatocyte to fasting.

  2005cited by this paper
• Snail and SIP1 increase cancer invasion by upregulating MMP family in hepatocellular carcinoma cells

  2004cited by this paper
• Recurrence or metastasis of HCC:predictors, early detection and experimental antiangiogenic therapy.

  2000cited by this paper

• Silencing of hsa_circ_0004771 inhibits proliferation and induces apoptosis in breast cancer through activation of miR-653 by targeting ZEB2 signaling pathway

  2019cites this paper