See Jeganathan and Breakspear (doi:10.1093/brain/awz132) for a scientific commentary on this article. Schumacher et al. report a marked and generalised slowing of whole-brain EEG dynamics in Lewy body dementia that distinguishes it from Alzheimer’s disease and healthy ageing. The slowing is related to a loss of dynamic interaction between basal ganglia-thalamic networks and large-scale cortical networks, and may contribute to fluctuating cognition.
Dysfunctional brain dynamics and their origin in Lewy body dementia
Julia Schumacher,Luis R. Peraza,M. Firbank,Alan J. Thomas,Marcus Kaiser,P. Gallagher,J. O'Brien,A. Blamire,John-Paul Taylor
Published 2019 in Brain : a journal of neurology
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PUBLICATION RECORD
- Publication year
2019
- Venue
Brain : a journal of neurology
- Publication date
2019-04-01
- Fields of study
Medicine
- Identifiers
- External record
- Source metadata
Semantic Scholar, PubMed
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