Gene expression pattern SRY, SOX9, and DAX1 expression patterns during human sex determination and gonadal development

No abstract is available for this paper.

• Publication year

  2000

• Venue

  Unknown venue

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Sry requires a CAG repeat domain for male sex determination in Mus musculus

  1999cited by this paper
• The human SRY protein is present in fetal and adult Sertoli cells and germ cells.

  1999cited by this paper
• Deletion of long-range regulatory elements upstream of SOX9 causes campomelic dysplasia.

  1998cited by this paper
• Dax1 antagonizes Sry action in mammalian sex determination

  1998cited by this paper
• Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression.

  1998cited by this paper
• Molecular Genetics of Early Human Development

  1997cited by this paper
• Mouse Dax1 expression is consistent with a role in sex determination as well as in adrenal and hypothalamus function

  1996cited by this paper
• A male-specific role for SOX9 in vertebrate sex determination.

  1996cited by this paper
• Sox9 expression during gonadal development implies a conserved role for the gene in testis differentiation in mammals and birds

  1996cited by this paper
• Expression of a linear Sry transcript in the mouse genital ridge

  1995cited by this paper
• Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene

  1994cited by this paper
• A dosage sensitive locus at chromosome Xp21 is involved in male to female sex reversal

  1994cited by this paper
• Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9.

  1994cited by this paper
• Sry is a transcriptional activator.

  1994cited by this paper
• Genetic evidence equating SRY and the testis-determining factor

  1990cited by this paper
• Developmental Stages in Human Embryos.

  1988cited by this paper
• The campomelic syndrome: review, report of 17 cases, and follow-up on the currently 17-year-old boy first reported by Maroteaux et al in 1971.

  1983cited by this paper

• Temporal dynamics of Sertoli and germ cell development in human foetal and prepubertal testis.

  2026cites this paper
• The evolution of gene regulatory programs controlling gonadal development in primates

  2025cites this paper
• Building a human pluripotent stem cell-based gonadal niche: improving in vitro systems with in vivo insights

  2025influential citation
• Single-cell exploration of gonadal somatic cell lineage specification during human sex determination.

  2025cites this paper
• Prenatal exposure to polystyrene nanoplastics caused testicular development toxicities and relative mechanisms in male offspring mice from embryo to adulthood

  2025cites this paper
• Emerging principles and models of human primordial germ cell development.

  2025cites this paper
• Sertoli cells as a hub in testicular development and male reproductive

  2025cites this paper
• Defining the cell and molecular origins of the primate ovarian reserve

  2025cites this paper
• Testicular differentiation in 46,XX DSD: an overview of genetic causes

  2024cites this paper
• Impacts of cancer therapy on male fertility: Past and present.

  2024cites this paper
• Temporal sex specific brain gene expression pattern during early rat embryonic development

  2024cites this paper
• Prior exposure to alkylating agents negatively impacts testicular organoid formation in cells obtained from childhood cancer patients

  2024cites this paper
• Inhibition of WNT/β-catenin signalling during sex-specific gonadal differentiation is essential for normal human fetal testis development

  2024cites this paper
• Unanticipated diagnosis of Swyer syndrome: a case report

  2024cites this paper
• The developmental dynamics of the human male germline.

  2023cites this paper
• Gene expression of male pathway genes sox9 and amh during early sex differentiation in a reptile departs from the classical amniote model

  2023cites this paper
• Single-cell transcriptome landscape of developing fetal gonads defines somatic cell lineage specification in humans

  2023influential citation
• Overview of single‐cell RNA sequencing analysis and its application to spermatogenesis research

  2023cites this paper
• Nuclear Receptor Gene Variants Underlying Disorders/Differences of Sex Development through Abnormal Testicular Development

  2023cites this paper
• Genetic control of typical and atypical sex development

  2023cites this paper
• Classic genetic and hormonal switches during fetal sex development and beyond

  2023cites this paper
• Etiology of Male Infertility: an Update

  2023cites this paper
• Ontogeny of mouse Sertoli, Leydig and peritubular myoid cells from embryonic day 10 to adulthood.

  2022cites this paper
• Deciphering Sex-Specific Differentiation of Human Fetal Gonads: Insight From Experimental Models

  2022cites this paper
• Applications for induced pluripotent stem cells in reproductive medicine

  2022cites this paper
• Development of the human ovary: Fetal through pubertal ovarian morphology, folliculogenesis and expression of cellular differentiation markers.

  2022cites this paper
• Germline stem cells in human

  2022cites this paper
• Early Gonadal Development and Sex Determination in Mammal

  2022cites this paper
• Adrenal hyperplasias in childhood: An update

  2022cites this paper
• Fetal germ cell development in humans, a link with infertility.

  2022cites this paper
• Single-cell roadmap of human gonadal development

  2021cites this paper
• Exposures during the prepuberty period and future offspring’s health: evidence from human cohort studies†

  2021cites this paper
• Single-cell analysis of the developing human testis reveals somatic niche cell specification and fetal germline stem cell establishment.

  2021cites this paper
• Environmental Impacts on Male Reproductive Development: Lessons from Experimental Models

  2021cites this paper
• Self-organising human gonads generated by a Matrigel-based gradient system

  2021cites this paper
• nr0b1 (DAX1) loss of function in zebrafish causes hypothalamic defects via abnormal progenitor proliferation and differentiation.

  2021cites this paper
• SEXUAL DIFFERENTIATION

  2020cites this paper
• Heterozygous deletion of Sox9 in mouse mimics the gonadal sex reversal phenotype associated with campomelic dysplasia in humans.

  2020cites this paper
• Dynamics of the transcriptional landscape during human fetal testis and ovary development.

  2020cites this paper
• Primary amenorrhea with Swyer syndrome: a rare case report

  2020cites this paper
• Gonadal development and sex determination in mouse.

  2020cites this paper
• Challenging human somatic testicular cell reassembly by protein kinase inhibition –setting up a functional in vitro test system

  2020cites this paper
• Sex Determination, Gonadal Sex Differentiation and Pl--asticity in Vertebrate Species.

  2020cites this paper
• Disorders of Sex Development—Novel Regulators, Impacts on Fertility, and Options for Fertility Preservation

  2020cites this paper
• Nonneoplastic Diseases of the Testis

  2020cites this paper
• The molecular pathways underlying early gonadal development.

  2019cites this paper
• Role of Nodal signalling in testis development and initiation of testicular cancer.

  2019cites this paper
• Update on the genetics of differences of sex development (DSD).

  2019cites this paper
• Dysregulation of FGFR signalling by a selective inhibitor reduces germ cell survival in human fetal gonads of both sexes and alters the somatic niche in fetal testes

  2019cites this paper
• A Study on Chromosomal Analysis of Patients with Primary Amenorrhea

  2019cites this paper
• In Vitro Spermatogenesis From Pluripotent Stem Cells

  2019cites this paper
• Genetics and Genomics of Early Gonad Development

  2019cites this paper
• Development of the Mammalian Ovary and Follicles

  2019cites this paper
• Genes and Gene Defects Affecting Gonadal Development and Sex Determination

  2019cites this paper
• Gene expression profiles of bovine genital ridges during sex determination and early differentiation of the gonads†

  2019cites this paper
• Nodal Signaling Regulates Germ Cell Development and Establishment of Seminiferous Cords in the Human Fetal Testis.

  2018cites this paper
• Testis Development.

  2018cites this paper
• A Human Gonadal Cell Model From Induced Pluripotent Stem Cells

  2018cites this paper
• A role for SOX9 in post-transcriptional processes: insights from the amphibian oocyte

  2018cites this paper
• Technique and Application of Sex-Sorted Sperm in Domestic Farm Animals

  2018cites this paper
• Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA Sequencing.

  2018cites this paper
• The evolutionary process of mammalian sex determination genes focusing on marsupial SRYs

  2018cites this paper
• Experimental models of testicular development and function using human tissue and cells.

  2018cites this paper
• Resource Deciphering Cell Lineage Specification during Male Sex Determination with Single-Cell RNA Sequencing

  2018cites this paper
• At the Crossroads of Fate—Somatic Cell Lineage Specification in the Fetal Gonad

  2018cites this paper
• The bovine sex-determining region Y ( Sry ) gene and its mRNA transcript are present in Y sperm but not X sperm of bulls

  2018cites this paper
• Segregation of mitochondrial DNA heteroplasmy through a developmental genetic bottleneck in human embryos

  2018cites this paper
• Human sex reversal is caused by duplication or deletion of core enhancers upstream of SOX9

  2018cites this paper
• Testicular Cancer in Relation to Testicular Dysgenesis Syndrome

  2018cites this paper
• CONSIDERACIONES GENERALES EN EL ESTABLECIMIENTO DEL SEXO EN MAMÍFEROS

  2017cites this paper
• Temporal expression pattern of genes during the period of sex differentiation in human embryonic gonads

  2017cites this paper
• A genomic atlas of human adrenal and gonad development

  2017cites this paper
• A Case of Primary Amenorrhea with Swyer Syndrome

  2017cites this paper
• 151 – Testicular Development and Descent

  2017cites this paper
• Sry and SoxE genes: How they participate in mammalian sex determination and gonadal development?

  2017cites this paper
• Male Sexual Differentiation

  2017cites this paper
• Anatomy and Development of the Male Reproductive System

  2017cites this paper
• Tridimensional Visualization and Analysis of Early Human Development.

  2017cites this paper
• Progress and future prospect of in vitro spermatogenesis

  2017cites this paper
• Characterization and expression of dax1 during embryonic and gonad development in the carp (Cyprinus carpio)

  2017cites this paper
• Origin and Quantitative Control of Sertoli Cells

  2017cites this paper
• Histological Assessment of Gonads in DSD: Relevance for Clinical Management

  2017cites this paper
• Dynamic epigenetic modifications during human fetal germ cell development

  2017influential citation
• Identical NR5A1 Missense Mutations in Two Unrelated 46,XX Individuals with Testicular Tissues

  2017cites this paper
• Soluble ADAM33 initiates airway remodeling to promote susceptibility for allergic asthma in early life

  2016cites this paper
• Genetic and epigenetic effects in sex determination.

  2016cites this paper
• Gametogenesis from Pluripotent Stem Cells.

  2016cites this paper
• Identification of NR0B1 as a novel androgen receptor co-repressor in mouse Sertoli cells.

  2016cites this paper
• nr0b1 (DAX1) mutation in zebrafish causes female-to-male sex reversal through abnormal gonadal proliferation and differentiation.

  2016cites this paper
• Immunohistochemical expression of SOX9 protein in immature, mature, and neoplastic canine Sertoli cells.

  2016cites this paper
• Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer

  2016cites this paper
• Artificial testis to study early gonadal development and germ cell differentiation

  2016cites this paper
• Role of the Transcription Factor SOX 9 in the tumorigenesis of some domestic animal neoplasms

  2016cites this paper
• Identification and Characterization of Y Chromosome and M Locus Genes in Anopheles and Aedes Mosquitoes Using the Chromosome Quotient Method

  2016cites this paper
• Signaling Pathways Involved in Mammalian Sex Determination and Gonad Development

  2016influential citation
• Methods for the Study of Gonadal Development.

  2016cites this paper
• Chapter 118 – Genetic Basis of Gonadal and Genital Development∗

  2016cites this paper
• Spatial sexual dimorphism of X and Y homolog gene expression in the human central nervous system during early male development

  2016cites this paper
• DAX1, an unusual member of the nuclear receptor superfamily with diverse functions

  2015cites this paper
• Estrogen receptor 1 (ESR1; ERα), not ESR2 (ERβ), modulates estrogen-induced sex reversal in the American alligator, a species with temperature-dependent sex determination.

  2015cites this paper