Biology of Extracellular HSP60

No abstract is available for this paper.

• Publication year

  2019

• Venue

  Heat Shock Proteins

• Publication date

  Unknown publication date

• Fields of study

  Biology

• Identifiers
  DOI 10.1007/978-3-030-02254-9_3
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

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• Anti-breast tumor activity of Eclipta extract in-vitro and in-vivo: novel evidence of endoplasmic reticulum specific localization of Hsp60 during apoptosis

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• Recombinant human HSP60 produced in ClearColi™ BL21(DE3) does not activate the NFκB pathway.

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• Intrathecal heat shock protein 60 mediates neurodegeneration and demyelination in the CNS through a TLR4- and MyD88-dependent pathway

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• PR65A Phosphorylation Regulates PP2A Complex Signaling

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• Adipocytes from New Zealand Obese Mice Exhibit Aberrant Proinflammatory Reactivity to the Stress Signal Heat Shock Protein 60

  2014cited by this paper
• Oxidative Stress Induces Monocyte Necrosis with Enrichment of Cell-Bound Albumin and Overexpression of Endoplasmic Reticulum and Mitochondrial Chaperones

  2013cited by this paper
• Amelioration of arthritis through mobilization of peptide-specific CD8+ regulatory T cells.

  2013cited by this paper
• Late onset motoneuron disorder caused by mitochondrial Hsp60 chaperone deficiency in mice.

  2013cited by this paper
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• GroEL and CCT are catalytic unfoldases mediating out-of-cage polypeptide refolding without ATP

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• Hsp60, a novel target for antitumor therapy: structure-function features and prospective drugs design.

  2013cited by this paper
• The Odyssey of Hsp60 from Tumor Cells to Other Destinations Includes Plasma Membrane-Associated Stages and Golgi and Exosomal Protein-Trafficking Modalities

  2012cited by this paper
• HSP60 is transported through the secretory pathway of 3‐MCA‐induced fibrosarcoma tumour cells and undergoes N‐glycosylation

  2012cited by this paper
• Heat Shock Protein 60 as a Mediator of Adipose Tissue Inflammation and Insulin Resistance

  2012cited by this paper
• Microglial LOX-1 reacts with extracellular HSP60 to bridge neuroinflammation and neurotoxicity.

  2012cited by this paper
• An altered peptide ligand corresponding to a novel epitope from heat-shock protein 60 induces regulatory T cells and suppresses pathogenic response in an animal model of adjuvant-induced arthritis

  2011cited by this paper
• Bacterial Heat Shock Protein 60, GroEL, Can Induce the Conversion of Naïve T Cells into a CD4+ CD25+ Foxp3-Expressing Phenotype

  2011cited by this paper
• Convergent Sets of Data from In Vivo and In Vitro Methods Point to an Active Role of Hsp60 in Chronic Obstructive Pulmonary Disease Pathogenesis

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• Identification of sumoylation targets, combined with inactivation of SMT3, reveals the impact of sumoylation upon growth, morphology, and stress resistance in the pathogen Candida albicans

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• The tumour-suppressive function of CLU is explained by its localisation and interaction with HSP60

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• The First Identification of Lysine Malonylation Substrates and Its Regulatory Enzyme*

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• Cord Blood CD4+ T Cells Respond to Self Heat Shock Protein 60 (HSP60)

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• The autoimmune concept of atherosclerosis

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• Heat-shock protein 60 translocates to the surface of apoptotic cells and differentiated megakaryocytes and stimulates phagocytosis

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• Heat shock protein 60 and adipocytes: characterization of a ligand-receptor interaction.

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• Hsp60 Is Actively Secreted by Human Tumor Cells

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• CD30 Discriminates Heat Shock Protein 60-Induced FOXP3+CD4+ T Cells with a Regulatory Phenotype

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• Heat shock protein 60 regulation of the mitochondrial permeability transition pore in tumor cells.

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• Regulation of heat shock protein 60 and 72 expression in the failing heart.

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• 4.0-Å resolution cryo-EM structure of the mammalian chaperonin TRiC/CCT reveals its unique subunit arrangement

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• Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Delivers Heat Shock Protein 60-Fused Antigen into the MHC Class I Presentation Pathway

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• Increased Toll-Like Receptor (TLR) Activation and TLR Ligands in Recently Diagnosed Type 2 Diabetic Subjects

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• Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions

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• Heat shock protein 60: Evidence for receptor‐mediated induction of proinflammatory mediators during adipocyte differentiation

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• Increased levels of ligands of Toll-like receptors 2 and 4 in type 1 diabetes

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• Heat Shock Protein 60, via MyD88 Innate Signaling, Protects B Cells from Apoptosis, Spontaneous and Induced1

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• Hsp60-mediated T cell stimulation is independent of TLR4 and IL-12.

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• The dual immunoregulatory roles of stress proteins.

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• GroEL stimulates protein folding through forced unfolding

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• Cell stress proteins in extracellular fluids: friend or foe?

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• Defining the TRiC/CCT interactome links chaperonin function to stabilization of newly-made proteins with complex topologies

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• Hsp60 Regulation of Tumor Cell Apoptosis*

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• Heat shock protein 60 induces inflammatory mediators in mouse adipocytes

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• Elevated Heat Shock Protein 60 Levels Are Associated With Higher Risk of Coronary Heart Disease in Chinese

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• Unusual cellular disposition of the mitochondrial molecular chaperones Hsp60, Hsp70 and Hsp10.

  2008cited by this paper
• A Vicious Cycle Involving Release of Heat Shock Protein 60 from Injured Cells and Activation of Toll-Like Receptor 4 Mediates Neurodegeneration in the CNS

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• Plasma heat shock protein 60 and cardiovascular disease risk: the role of psychosocial, genetic, and biological factors

  2007cited by this paper
• p53 Tumor Suppressor Gene: A Critical Molecular Target for UV Induction and Prevention of Skin Cancer †

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• Heat shock protein 60: regulatory role on innate immune cells

  2007cited by this paper
• Differential Regulation of Circulating Levels of Molecular Chaperones in Patients Undergoing Treatment for Periodontal Disease

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• HSP60 trafficking in adult cardiac myocytes: role of the exosomal pathway.

  2007cited by this paper
• Cytosolic Accumulation of HSP60 during Apoptosis with or without Apparent Mitochondrial Release

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• Heat shock protein 60 modified with O‐linked N‐acetylglucosamine is involved in pancreatic β‐cell death under hyperglycemic conditions

  2006cited by this paper
• Association between plasma levels of heat shock protein 60 and cardiovascular disease in patients with diabetes mellitus.

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• At the gates of death.

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• Role of nitric oxide in heat shock protein induced apoptosis of γδT cells

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• Chloroplast heat shock protein Cpn60 from Chlamydomonas reinhardtii exhibits a novel function as a group II intron‐specific RNA‐binding protein

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• Signalling role of adipose tissue: adipokines and inflammation in obesity.

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• The chaperonins: perspectives from the Archaea.

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• H9724, a Monoclonal Antibody to Borrelia burgdorferi's Flagellin, Binds to Heat Shock Protein 60 (HSP60) Within Live Neuroblastoma Cells: A Potential Role for HSP60 in Peptide Hormone Signaling and in an Autoimmune Pathogenesis of the Neuropathy of Lyme Disease

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• Serum soluble heat shock protein 60 is elevated in subjects with atherosclerosis in a general population.

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