Recent Results in Alamethicin Research

No abstract is available for this paper.

• Publication year

  2013

• Venue

  Chemistry and Biodiversity

• Publication date

  2013-05-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.1002/cbdv.201200390PMID 23681724
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Defining the pathogenesis of human mtDNA mutations using a yeast model: the case of T8851C.

  2013cited by this paper
• Ethylmalonic acid impairs brain mitochondrial succinate and malate transport.

  2012cited by this paper
• Evaluation of molecularity of rate-limiting step of pore formation by antimicrobial peptides studied using mitochondria as a biosensor.

  2012cited by this paper
• Chemotherapy Drugs Form Ion Pores in Membranes Due to Physical Interactions with Lipids

  2012cited by this paper
• Control of leakage activities of alamethicin analogs by metals: side chain-dependent adverse gating response to Zn(2+).

  2012cited by this paper
• Determining the mechanism of membrane permeabilizing peptides: identification of potent, equilibrium pore-formers.

  2012cited by this paper
• Nonseed plant Selaginella moellendorffii has both seed plant and microbial types of terpene synthases

  2012cited by this paper
• Influence of the membrane dipole potential on peptide binding to lipid bilayers.

  2012cited by this paper
• Observing a model ion channel gating action in model cell membranes in real time in situ: membrane potential change induced alamethicin orientation change.

  2012cited by this paper
• Charge distribution and imperfect amphipathicity affect pore formation by antimicrobial peptides.

  2012cited by this paper
• Mechanical actuation of ion channels using a piezoelectric planar patch clamp system.

  2012cited by this paper
• Cyclodextrin-scaffolded alamethicin with remarkably efficient membrane permeabilizing properties and membrane current conductance.

  2012cited by this paper
• Absence of Ca2+-Induced Mitochondrial Permeability Transition but Presence of Bongkrekate-Sensitive Nucleotide Exchange in C. crangon and P. serratus

  2012cited by this paper
• Peptaibols from two unidentified fungi of the order Hypocreales with cytotoxic, antibiotic, and anthelmintic activities

  2012cited by this paper
• 20‐Residue and 11‐residue peptaibols from the fungus Trichoderma longibrachiatum are synergistic in forming Na+/K+‐permeable channels and adverse action towards mammalian cells

  2012cited by this paper
• Metabolic Difference of CZ48 in Human and Mouse Liver Microsomes

  2012cited by this paper
• Prediction of Liver Injury Induced by Chemicals in Human With a Multiparametric Assay on Isolated Mouse Liver Mitochondria

  2012cited by this paper
• Optimized Assays for Human UDP-Glucuronosyltransferase (UGT) Activities: Altered Alamethicin Concentration and Utility to Screen for UGT Inhibitors

  2012cited by this paper
• Characterization of In Vitro Glucuronidation Clearance of a Range of Drugs in Human Kidney Microsomes: Comparison with Liver and Intestinal Glucuronidation and Impact of Albumin

  2012cited by this paper
• High Ca2+ load promotes hydrogen peroxide generation via activation of α-glycerophosphate dehydrogenase in brain mitochondria.

  2012cited by this paper
• Antimicrobial and cell-penetrating peptides induce lipid vesicle fusion by folding and aggregation

  2011cited by this paper
• Diabetes Mellitus Reduces Activity of Human UDP-Glucuronosyltransferase 2B7 in Liver and Kidney Leading to Decreased Formation of Mycophenolic Acid Acyl-Glucuronide Metabolite

  2011cited by this paper
• Imaging multiple conductance states in an alamethicin pore.

  2011cited by this paper
• Inhibitory Effects of Commonly Used Herbal Extracts on UDP-Glucuronosyltransferase 1A4, 1A6, and 1A9 Enzyme Activities

  2011cited by this paper
• Meet Me on the Other Side: Trans-Bilayer Modulation of a Model Voltage-Gated Ion Channel Activity by Membrane Electrostatics Asymmetry

  2011cited by this paper
• Correlation of intrinsic in vitro and in vivo clearance for drugs metabolized by hepatic UDP-glucuronosyltransferases in rats.

  2011cited by this paper
• Comparison of distance information in [TOAC1, Glu(OMe)7, 18, 19] alamethicin F50/5 from paramagnetic relaxation enhancement measurements with data obtained from an X‐ray diffraction‐based model

  2011cited by this paper
• Long-term-stable ether-lipid vs conventional ester-lipid bicelles in oriented solid-state NMR: altered structural information in studies of antimicrobial peptides.

  2011cited by this paper
• Rb(+) occlusion stabilized by vanadate in gastric H(+)/K(+)-ATPase at 25°C.

  2011cited by this paper
• cis- and trans-Regulation of miR163 and Target Genes Confers Natural Variation of Secondary Metabolites in Two Arabidopsis Species and Their Allopolyploids[W][OA]

  2011cited by this paper
• Prediction of the intestinal first-pass metabolism of CYP3A and UGT substrates in humans from in vitro data.

  2011cited by this paper
• Cyclophilin D-Sensitive Mitochondrial Permeability Transition in Adult Human Brain and Liver Mitochondria

  2011cited by this paper
• Effects of Cell Differentiation and Assay Conditions on the UDP-Glucuronosyltransferase Activity in Caco-2 Cells

  2011cited by this paper
• Identification of Novel Metoclopramide Metabolites in Humans: In Vitro and In Vivo Studies

  2010cited by this paper
• Use of Human Cancer Cell Lines Mitochondria to Explore the Mechanisms of BH3 Peptides and ABT-737-Induced Mitochondrial Membrane Permeabilization

  2010cited by this paper
• Molecular modeling of the reductase domain to elucidate the reaction mechanism of reduction of peptidyl thioester into its corresponding alcohol in non-ribosomal peptide synthetases

  2010cited by this paper
• Substantiation in Enterococcus faecalis of Dose-Dependent Resistance and Cross-Resistance to Pore-Forming Antimicrobial Peptides by Use of a Polydiacetylene-Based Colorimetric Assay

  2010cited by this paper
• Mitochondria as a source of mechanical signals in cardiomyocytes.

  2010cited by this paper
• Trichoderma viride cellulase induces resistance to the antibiotic pore-forming peptide alamethicin associated with changes in the plasma membrane lipid composition of tobacco BY-2 cells

  2010cited by this paper
• Differences between Human and Rat Intestinal and Hepatic Bisphenol A Glucuronidation and the Influence of Alamethicin on In Vitro Kinetic Measurements

  2010cited by this paper
• Antimicrobial peptides bind more strongly to membrane pores.

  2010cited by this paper
• BAX insertion, oligomerization, and outer membrane permeabilization in brain mitochondria: role of permeability transition and SH-redox regulation.

  2010cited by this paper
• What are the sources of hydrogen peroxide production by heart mitochondria?

  2010cited by this paper
• Interactions of alamethicin with model cell membranes investigated using sum frequency generation vibrational spectroscopy in real time in situ.

  2010cited by this paper
• Antimicrobial peptides in toroidal and cylindrical pores.

  2010cited by this paper
• Hypersensitive‐Like Response to the Pore‐Former Peptaibol Alamethicin in Arabidopsis Thaliana

  2010cited by this paper
• Neuron specific metabolic adaptations following multi-day exposures to oxygen glucose deprivation.

  2010cited by this paper
• Alamethicin-induced electrical long distance signaling in plants

  2010cited by this paper
• Effect of α-helical peptides on liposome structure: a comparative study of melittin and alamethicin.

  2010cited by this paper
• Fractional polymerization of a suspended planar bilayer creates a fluid, highly stable membrane for ion channel recordings.

  2010cited by this paper
• Conformational and interfacial analyses of K3A18K3 and alamethicin in model membranes.

  2009cited by this paper
• Residue-specific information about the dynamics of antimicrobial peptides from (1)H-(15)N and (2)H solid-state NMR spectroscopy.

  2009cited by this paper
• Endoplasmic reticulum stress underlying the pro-apoptotic effect of epigallocatechin gallate in mouse hepatoma cells.

  2009cited by this paper
• Comparing induction at an early and late step in signal transduction mediating indirect defence in Brassica oleracea

  2009cited by this paper
• Ion channel and toxin measurement using a high throughput lipid membrane platform.

  2009cited by this paper
• In vitro and in vivo antitrypanosomal activities of three peptide antibiotics: leucinostatin A and B, alamethicin I and tsushimycin

  2009cited by this paper
• Acrebol, a novel toxic peptaibol produced by an Acremonium exuviarum indoor isolate

  2009cited by this paper
• Mitochondrial micro-calpain is not involved in the processing of apoptosis-inducing factor.

  2009cited by this paper
• Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase.

  2009cited by this paper
• Chemical labeling strategy with (R)- and (S)-trifluoromethylalanine for solid state 19F NMR analysis of peptaibols in membranes.

  2009cited by this paper
• Relative Importance of Intestinal and Hepatic Glucuronidation—Impact on the Prediction of Drug Clearance

  2009cited by this paper
• Novel mycotoxin from Acremonium exuviarum is a powerful inhibitor of the mitochondrial respiratory chain complex III.

  2009cited by this paper
• Induction of a non-specific permeability transition in mitochondria from Yarrowia lipolytica and Dipodascus (Endomyces) magnusii yeasts

  2009cited by this paper
• Prediction of Drug Clearance by Glucuronidation from in Vitro Data: Use of Combined Cytochrome P450 and UDP-Glucuronosyltransferase Cofactors in Alamethicin-Activated Human Liver Microsomes

  2009cited by this paper
• The RH 421 styryl dye induced, pore model-dependent modulation of antimicrobial peptides activity in reconstituted planar membranes.

  2009cited by this paper
• Structure of self-aggregated alamethicin in ePC membranes detected by pulsed electron-electron double resonance and electron spin echo envelope modulation spectroscopies.

  2009cited by this paper
• Membranes of five-fold alamethicin-resistantStaphylococcus aureus, Enterococcus faecalis andBacillus cereus show decreased interactions with alamethicin due to changes in membrane fluidity and surface charge

  2009cited by this paper
• Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs.

  2009cited by this paper
• Incorporation of antimicrobial peptides into membranes: a combined liquid-state NMR and molecular dynamics study of alamethicin in DMPC/DHPC bicelles.

  2009cited by this paper
• Structure and alignment of the membrane-associated peptaibols ampullosporin A and alamethicin by oriented 15N and 31P solid-state NMR spectroscopy.

  2009cited by this paper
• Parkin selectively alters the intrinsic threshold for mitochondrial cytochrome c release.

  2009cited by this paper
• Regulation of callose synthase activity in situ in alamethicin-permeabilized Arabidopsis and tobacco suspension cells

  2009cited by this paper
• Bioelectronic silicon nanowire devices using functional membrane proteins

  2009cited by this paper
• The antimicrobial peptide gramicidin S permeabilizes phospholipid bilayer membranes without forming discrete ion channels.

  2008cited by this paper
• Using ion channel-forming peptides to quantify protein-ligand interactions.

  2008cited by this paper
• Lipid membrane domain formation and alamethicin aggregation studied by calorimetry, sound velocity measurements, and atomic force microscopy.

  2008cited by this paper
• Reactive Oxygen Species Production in Energized Cardiac Mitochondria During Hypoxia/Reoxygenation: Modulation by Nitric Oxide

  2008cited by this paper
• Regio- and Stereospecific N-Glucuronidation of Medetomidine: The Differences between UDP Glucuronosyltransferase (UGT) 1A4 and UGT2B10 Account for the Complex Kinetics of Human Liver Microsomes

  2008cited by this paper
• Structure of the alamethicin pore reconstructed by x-ray diffraction analysis.

  2008cited by this paper
• mt-Nd2a Suppresses Reactive Oxygen Species Production by Mitochondrial Complexes I and III*

  2008cited by this paper
• Peptide aggregation and pore formation in a lipid bilayer: a combined coarse-grained and all atom molecular dynamics study.

  2008cited by this paper
• Activity modulation of certain ion-pore forming proteins by electric properties of artificial lipid membranes

  2008cited by this paper
• Single-Molecule Investigation of the Influence Played by Lipid Rafts on Ion Transport and Dynamic Features of the Pore-Forming Alamethicin Oligomer

  2008cited by this paper
• Oligomeric BAX induces mitochondrial permeability transition and complete cytochrome c release without oxidative stress.

  2008cited by this paper
• Mitochondrial swelling measurement in situ by optimized spatial filtering: astrocyte-neuron differences.

  2008cited by this paper
• Lateral heterogeneities in supported bilayers from pure and mixed phosphatidylethanolamine demonstrating hydrogen bonding capacity

  2008cited by this paper
• Fluorescence assay for mitochondrial permeability transition in cardiomyocytes cultured in a microtiter plate.

  2008cited by this paper
• Methylmalonate inhibits succinate-supported oxygen consumption by interfering with mitochondrial succinate uptake

  2008cited by this paper
• Peptaibiomics: Towards a Myriad of Bioactive Peptides Containing Cα‐Dialkylamino Acids?

  2008cited by this paper
• Identification and Regulation of TPS04/GES, an Arabidopsis Geranyllinalool Synthase Catalyzing the First Step in the Formation of the Insect-Induced Volatile C16-Homoterpene TMTT[W]

  2008cited by this paper
• PELDOR conformational analysis of bis-labeled alamethicin aggregated in phospholipid vesicles.

  2008cited by this paper
• The Trichoderma brevicompactum clade: a separate lineage with new species, new peptaibiotics, and mycotoxins

  2008cited by this paper
• New Sequences, Constituents, and Producers of Peptaibiotics: An Updated Review

  2007cited by this paper
• Self-aggregation of spin-labeled alamethicin in ePC vesicles studied by pulsed electron - electron double resonance.

  2007cited by this paper
• Entropy-driven softening of fluid lipid bilayers by alamethicin.

  2007cited by this paper
• Probing the outer mitochondrial membrane in cardiac mitochondria with nanoparticles.

  2007cited by this paper
• Effect of mitochondrial genome rearrangement on respiratory activity, photosynthesis, photorespiration and energy status of MSC16 cucumber (Cucumis sativus) mutant.

  2007cited by this paper
• Conformational Analysis of TOAC‐Labelled Alamethicin F50/5 Analogues

  2007cited by this paper
• pH modulation of transport properties of alamethicin oligomers inserted in zwitterionic-based artificial lipid membranes.

  2007cited by this paper
• Membrane Permeabilization of a Mammalian Neuroendocrine Cell Type (PC12) by the Channel‐Forming Peptides Zervamicin, Alamethicin, and Gramicidin

  2007cited by this paper

• Comprehensive insights into microbial-derived antimicrobial peptides (AMPs): classification, mechanisms, applications, and purification strategies

  2025cites this paper
• Marine-derived new peptaibols with antibacterial activities by targeting bacterial membrane phospholipids

  2025cites this paper
• A Journey into the Blue: Current Knowledge and Emerging Insights into Marine-Derived Peptaibols

  2025cites this paper
• Antimicrobial Peptides from Frogs of the Glandirana Genus

  2024cites this paper
• Trichoderma harzianum Peptaibols Stimulate Plant Plasma Membrane H+-ATPase Activity

  2023cites this paper
• Peptide analogs of a Trichoderma peptaibol effectively control downy mildew in the vineyard.

  2023cites this paper
• Peptaibols as Potential Antifungal and Anticancer Antibiotics: Current and Foreseeable Development (Review)

  2021cites this paper
• Molecular methods unravel the biosynthetic potential of Trichoderma species

  2021cites this paper
• YPR2 is a regulator of light modulated carbon and secondary metabolism in Trichoderma reesei

  2019cites this paper
• Accelerated Molecular Dynamics Applied to the Peptaibol Folding Problem

  2019cites this paper
• Structural Diversity and Bioactivities of Peptaibol Compounds From the Longibrachiatum Clade of the Filamentous Fungal Genus Trichoderma

  2019cites this paper
• Hyporientalin A, an anti-Candida peptaibol from a marine Trichoderma orientale

  2018cites this paper
• Peptaibols as a model for the insertions of chemical modifications.

  2018cites this paper
• How are 1,2,3-triazoles accommodated in helical secondary structures?

  2018cites this paper
• Tarımsal Üretimde Yararlanılan Trichoderma Ürünleri ve Metabolitleri

  2017cites this paper
• Enhancing the Antimicrobial Activity of Alamethicin F50/5 by Incorporating N-terminal Hydrophobic Triazole Substituents.

  2017cites this paper
• Diversity Profile and Dynamics of Peptaibols Produced by Green Mould Trichoderma Species in Interactions with Their Hosts Agaricus bisporus and Pleurotus ostreatus

  2017cites this paper
• Unique amalgamation of primary and secondary structural elements transform peptaibols into potent bioactive cell-penetrating peptides

  2017cites this paper
• Cellular and molecular insight into the inhibition of primary root growth of Arabidopsis induced by peptaibols, a class of linear peptide antibiotics mainly produced by Trichoderma spp.

  2016cites this paper
• Alamethicin Supramolecular Organization in Lipid Membranes from 19F Solid-State NMR.

  2016cites this paper
• Single-cell, time-resolved study of the effects of the antimicrobial peptide alamethicin on Bacillus subtilis.

  2016cites this paper
• Characterizing the structural and folding properties of long‐sequence hypomurocin B peptides and their analogs

  2016cites this paper
• A Rapid and Quantitative Flow Cytometry Method for the Analysis of Membrane Disruptive Antimicrobial Activity

  2016cites this paper
• Development and Evaluation of Lipodisks Intended for Use as Biomimetic Membranes and Drug Carriers

  2016cites this paper
• Biosynthesis and Molecular Genetics of Peptaibiotics—Fungal Peptides Containing Alpha, Alpha-Dialkyl Amino Acids

  2015cites this paper
• Substitution de la liaison amide par un triazole 1,4- disubstitué dans le but d’étudier l’impact de ce remplacement sur la structure secondaire et l’activité biologique de peptides

  2015cites this paper
• Peptaibiotics and peptaibols from fungi

  2015cites this paper
• The fluorescence and infrared absorption probe para‐cyanophenylalanine: Effect of labeling on the behavior of different membrane‐interacting peptides

  2015cites this paper
• Improved Strategy for the Synthesis of the Anticancer Agent Culicinin D

  2015cites this paper
• Studying the Structural and Folding Features of Long‐Sequence Trichobrachin Peptides

  2015cites this paper
• Electrophysiology Investigation of Trichogin GA IV Activity in Planar Lipid Membranes Reveals Ion Channels of Well‐Defined Size

  2014cites this paper
• Solution Synthesis, Conformational Analysis, and Antimicrobial Activity of Three Alamethicin F50/5 Analogs Bearing a Trifluoroacetyl Label

  2014cites this paper
• Attempts toward the Synthesis of the Peptaibol Antiamoebin by Using the ‘Azirine/Oxazolone Method’

  2013cites this paper
• Rapid bioactivity-based pre-screening method for the detection of peptaibiotic-producing Trichoderma strains

  2013cites this paper
• Mass spectrometric investigation of alamethicin

  2013cites this paper