Arabidopsis FAD2 gene encodes the enzyme that is essential for polyunsaturated lipid synthesis.

No abstract is available for this paper.

• Publication year

  1994

• Venue

  The Plant Cell

• Publication date

  1994-01-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1105/tpc.6.1.147PMID 7907506PMCID PMC160423
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Arabidopsis requires polyunsaturated lipids for low-temperature survival.

  1993cited by this paper
• Isolation of a delta 6-desaturase gene from the cyanobacterium Synechocystis sp. strain PCC 6803 by gain-of-function expression in Anabaena sp. strain PCC 7120.

  1993cited by this paper
• Biosynthesis of Polyunsaturated Fatty Acids

  1993cited by this paper
• Cloning of Higher Plant [omega]-3 Fatty Acid Desaturases

  1993cited by this paper
• Molecular dynamics simulations of a lipid bilayer and of hexadecane: an investigation of membrane fluidity.

  1993cited by this paper
• Stearoyl-acyl carrier protein delta 9 desaturase from Ricinus communis is a diiron-oxo protein.

  1993cited by this paper
• A gene encoding a chloroplast omega-3 fatty acid desaturase complements alterations in fatty acid desaturation and chloroplast copy number of the fad7 mutant of Arabidopsis thaliana.

  1993cited by this paper
• Global and local genome mapping in Arabidopsis thaliana by using recombinant inbred lines and random amplified polymorphic DNAs.

  1992cited by this paper
• Arabidopsis mutants deficient in polyunsaturated fatty acid synthesis. Biochemical and genetic characterization of a plant oleoyl-phosphatidylcholine desaturase.

  1992influential reference
• Map-based cloning of a gene controlling omega-3 fatty acid desaturation in Arabidopsis.

  1992cited by this paper
• A role for membrane lipid polyunsaturation in chloroplast biogenesis at low temperature.

  1992cited by this paper
• Expression of a coriander desaturase results in petroselinic acid production in transgenic tobacco.

  1992cited by this paper
• Stearoyl-acyl-carrier-protein desaturase from higher plants is structurally unrelated to the animal and fungal homologs.

  1991cited by this paper
• T‐DNA insertion mutagenesis in Arabidopsis: mutational spectrum

  1991cited by this paper
• Glycerolipid Synthesis: Biochemistry and Regulation

  1991cited by this paper
• Lambda YES: a multifunctional cDNA expression vector for the isolation of genes by complementation of yeast and Escherichia coli mutations.

  1991influential reference
• Embryonic Lethals and T-DNA Insertional Mutagenesis in Arabidopsis.

  1991cited by this paper
• Plant Lipids: Metabolism, Mutants, and Membranes

  1991cited by this paper
• Isolation of EMS-induced mutants in Arabidopsis altered in seed fatty acid composition

  1990cited by this paper
• Three-dimensional structure of the free radical protein of ribonucleotide reductase

  1990influential reference
• Enhancement of chilling tolerance of a cyanobacterium by genetic manipulation of fatty acid desaturation

  1990influential reference
• The OLE1 gene of Saccharomyces cerevisiae encodes the delta 9 fatty acid desaturase and can be functionally replaced by the rat stearoyl-CoA desaturase gene.

  1990cited by this paper
• Interfacial catalysis: the mechanism of phospholipase A2

  1990cited by this paper
• Mutants of Arabidopsis with alterations in seed lipid fatty acid composition

  1990cited by this paper
• Identification of a consensus motif for retention of transmembrane proteins in the endoplasmic reticulum.

  1990cited by this paper
• A Dwarf Mutant of Arabidopsis Generated by T-DNA Insertion Mutagenesis

  1989cited by this paper
• Topography of membrane proteins.

  1989cited by this paper
• Fatty acid composition of leaf lipids determined after combined digestion and fatty acid methyl ester formation from fresh tissue.

  1986cited by this paper
• A mutant of Arabidopsis deficient in c(18:3) and c(16:3) leaf lipids.

  1986cited by this paper
• Construction and sequence of cDNA for rat liver stearyl coenzyme A desaturase.

  1986cited by this paper
• Extraction of DNA from milligram amounts of fresh, herbarium and mummified plant tissues

  1985cited by this paper
• The induction and characterization of rat liver stearyl-CoA desaturase mRNA.

  1985cited by this paper
• A comprehensive set of sequence analysis programs for the VAX

  1984influential reference
• BINUCLEAR IRON COMPLEXES IN METHEMERYTHRIN AND AZIDOMETHEMERYTHRIN AT 2. 0-A RESOLUTION.

  1984cited by this paper
• BINUCLEAR IRON COMPLEXES IN METHEMERYTHRIN AND AZIDOMETHEMERYTHRIN AT 2.0-Å RESOLUTION

  1984cited by this paper
• Plant Acyl Lipids: Structure, Distribution, and Analysis

  1980cited by this paper
• Transfection and transformation of Agrobacterium tumefaciens

  1978cited by this paper
• Topography of membrane proteins.

  1975cited by this paper
• Purification and properties of rat liver microsomal stearyl coenzyme A desaturase.

  1974cited by this paper

• Multiomics Approach Reveals the Inhibitory Effects of Protocatechuic Acid on the Marine Dinoflagellate Scrippsiella acuminata

  2026cites this paper
• ER–plastid contact sites as molecular crossroads for plastid lipid biosynthesis

  2025cites this paper
• Hydroxy fatty acid analysis in seeds of Physaria and Paysonia species

  2025cites this paper
• Natural Variation in TaFAD8‐D Promoter Enhances Thermotolerance in Wheat Through Fatty Acid and Lipid Remodelling

  2025cites this paper
• Genome Wide Identification of Sesame Dof Transcription Factors and Functional Analysis of SiDof8, SiDof10 and SiDof34 in Fatty Acid Synthesis

  2025cites this paper
• Molecular breeding approaches for the improvement of oil content and fatty acid composition in exotic‐derived maize germplasm

  2025cites this paper
• The proteome-scale study of iron-binding proteins of bread wheat.

  2025cites this paper
• Unveiling the Impact of Vernalisation on Seed Oil Content and Fatty Acid Composition in Rapeseed (Brassica napus L.) Through Simulated Shorter Winters

  2025cites this paper
• Complete replacement of Arabidopsis oil-producing enzymes with heterologous diacylglycerol acyltransferases

  2025cites this paper
• Bioengineering of long-chain polyunsaturated fatty acids in oilseed crops.

  2025cites this paper
• Insights into membrane-bound fatty acid desaturase genes in tigernut (Cyperus esculentus L.), an oil-rich tuber plant in Cyperaceae

  2025cites this paper
• Overexpression of the patatin-related phospholipase A gene, PgpPLAIIIβ, in ginseng adventitious roots reduces lignin and ginsenoside content while increasing fatty acid content.

  2025cites this paper
• A method for maintaining the release of co-suppression and maximally restoring the RDR6 expression

  2025cites this paper
• SYNTAXIN OF PLANTS 81 regulates fatty acid desaturation by mediating Acyl Carrier Protein Desaturase 5 during seed development in Arabidopsis thaliana

  2025cites this paper
• Genetic diversity and adaptive evolutionary history of Sapindus in China: insights from whole‐genome resequencing of 100 representative individuals

  2025cites this paper
• Development of novel transgene‐free high‐oleic peanuts through CRISPR‐Cas9‐mediated gene editing of two AhFAD2 homologues

  2025cites this paper
• New era to prepare human milk fat substitutes: 1,3-Dioleoyl-2-palmitoyl-glycerol.

  2025cites this paper
• Integrative analysis of transcriptome and metabolome reveals molecular mechanisms of dynamic change of storage substances during dehydration and drying process in peanuts (Arachis hypogaea L.)

  2025cites this paper
• Comparative Analysis of the Expression of Genes Involved in Fatty Acid Synthesis Across Camelina Varieties

  2025cites this paper
• The chromosome-scale genomes of two cultivated safflowers (Carthamus tinctorius) provide insights into the genetic diversity resulting from domestication

  2025cites this paper
• Creating ultra‐high linolenic acid camelina by co‐expressing AtFAD2sm with synonymous mutations and BnFAD3 in the fae1 mutant

  2025cites this paper
• Transcriptional Analysis of Different Cultivars and Genome-Wide Identification of FAD Gene Family in Tree Peony

  2024cites this paper
• Improving linolenic acid content in rapeseed oil by overexpression of CsFAD2 and CsFAD3 genes

  2024cites this paper
• Chloroplast-localized transporter OsNTP1 mediates cadmium transport from root to shoot and sugar metabolism in rice.

  2024cites this paper
• Identification of SNPs associated with fatty acid contents in mutant soybean lines by a genome-wide association study

  2024cites this paper
• Crucial amino acids identified in Δ12 fatty acid desaturases related to linoleic acid production in Perilla frutescens

  2024cites this paper
• Identification and Analysis of KAS II, FAT, SAD, and FAD Gene Families in Hippophae rhamnoides

  2024cites this paper
• Arabidopsis seeds altered in the circadian clock protein TOC1 are characterized by higher level of linolenic acid.

  2024cites this paper
• Creation of rapeseed germplasm with high polyunsaturated fatty acid content by wild-relative introgression from Brassica carinata

  2024cites this paper
• The Molecular Cloning and Functional Analysis of the FAD2 Gene in Hippophe rhamnoids L.

  2024cites this paper
• Overexpression of the Phosphatidylcholine:DiacylglycerolCholinephosphotransferase (PDCT) gene increases carbon flux toward triacylglycerol (TAG) synthesis in Camelinasativa seeds.

  2024cites this paper
• Exploration of allelic diversity reveals a novel FAD2 (Oleate desaturase) gene in Brassica juncea

  2024cites this paper
• Advancements and challenges in CRISPR/cas genome editing for legume crops

  2024cites this paper
• Homologous Delta-12 Fatty Acid Desaturase (FAD2) Genes Affect Gene Expression and Linoleic Acid Levels in Lentinula edodes under Heat Stress

  2024influential citation
• PUFA-PLs biosynthesis enzymes contribute to pathogenic development of rice blast fungus Magnaporthe oryzae

  2024cites this paper
• Chia (Salvia hispanica L.), a functional 'superfood': new insights into its botanical, genetic and nutraceutical characteristics.

  2024cites this paper
• Utility of Arabidopsis KASII Promoter in Development of an Effective CRISPR/Cas9 System for Soybean Genome Editing and Its Application in Engineering of Soybean Seeds Producing Super-High Oleic and Low Saturated Oils.

  2024cites this paper
• Advancing PAM-less genome editing in soybean using CRISPR-SpRY

  2024cites this paper
• Genetic variation of a heat shock transcription factor modulates cold tolerance in maize.

  2024cites this paper
• Functional genomics of Brassica napus: Progresses, challenges, and perspectives.

  2024cites this paper
• Molecular insights into the oleic acid accumulation in safflower

  2024cites this paper
• The constructed high-density genetic map helps to explore the genetic regulation of erucic acid, oleic acid, and linolenic acid contents in Brassica juncea

  2024cites this paper
• Temperature affects major fatty acid biosynthesis in noug (Guizotia abyssinica) self-compatible lines

  2024cites this paper
• Arabidopsis diacylglycerol acyltransferase1 mutants require fatty acid desaturation for normal seed development.

  2024cites this paper
• Quantitative Investigation of FAD2 Cosuppression Reveals RDR6-Dependent and RDR6-Independent Gene Silencing Pathways

  2023cites this paper
• Identification of Quantitative Trait Nucleotides and Development of Diagnostic Markers for Nine Fatty Acids in the Peanut

  2023cites this paper
• Inter-Organellar Effects of Defective ER-Localized Linolenic Acid Formation on Thylakoid Lipid Composition, Non-Photochemical Quenching of Chlorophyll Fluorescence and Xanthophyll Cycle Activity in the Arabidopsis fad3 Mutant.

  2023cites this paper
• A chromosome-level genome assembly provides insights into Cornus wilsoniana evolution, oil biosynthesis, and floral bud development

  2023cites this paper
• Inter-Organellar Effects of Defective ER-localized Linolenic Acid Formation on Thylakoid Lipid Composition and Xanthophyll-Cycle Pigment De-epoxidation in the Arabidopsis fad3 mutant

  2023influential citation
• Key FAD2, FAD3, and SAD Genes Involved in the Fatty Acid Synthesis in Flax Identified Based on Genomic and Transcriptomic Data

  2023cites this paper
• Regulation of seed traits in soybean

  2023cites this paper
• Identification of lncRNAs and Their Regulatory Network Involved in Oil Biosynthesis in Developing Seeds of Yellowhorn (Xanthoceras sorbifolium)

  2023cites this paper
• Multi-omics analyses of the effect of carbon ion beam irradiation on cannabis fructus (Cannabis sativa L.) composition

  2023cites this paper
• Biological Characteristics and Functional Analysis of the Linoleic Acid Synthase Gene ZjFAD2 in Jujube

  2023cites this paper
• Comparative transcriptomic and evolutionary analysis of FAD-like genes of Brassica species revealed their role in fatty acid biosynthesis and stress tolerance

  2023cites this paper
• A mutant cotton fatty acid desaturase 2-1d allele causes protein mistargeting and altered seed oil composition

  2023influential citation
• Diversity of fatty acid biosynthesis genes across the soybean pangenome

  2023cites this paper
• Metabolomics and Transcriptomics Analyses Reveals the Molecular Regulatory Mechanisms of Walnut (Juglans regia L.) Embryos in Response to Shade Treatment

  2023cites this paper
• Developmental regulation and physical interaction among enzymes involved in sorgoleone biosynthesis.

  2023cites this paper
• Metabolomics and Transcriptomics Provide Insights into Lipid Biosynthesis in the Embryos of Walnut (Juglans regia L.)

  2023cites this paper
• Lipidomics characterized TAG biosynthesis of developing kernels in three walnut cultivars in Xinjiang region.

  2023cites this paper
• Transcriptome profiling of unigenes participating in salt tolerance in purslane (Portulaca oleracea) under salinity stress

  2023influential citation
• Osmotic stress-induced localisation switch of CBR1 from mitochondria to the endoplasmic reticulum triggers ATP production via β-oxidation to respond to osmotic shock.

  2023cites this paper
• Do betaine lipids replace phosphatidylcholine as fatty acid editing hubs in microalgae?

  2023cites this paper
• Effects of Temperature and Salt Stress on the Expression of delta-12 Fatty Acid Desaturase Genes and Fatty Acid Compositions in Safflower

  2023cites this paper
• Biotechnology for Improving Hydroxy Fatty Acids Production in Lesquerella (Physaria fendleri)

  2023influential citation
• Indigenous and commercial isolates of arbuscular mycorrhizal fungi display differential effects in Pyrus betulaefolia roots and elicit divergent transcriptomic and metabolomic responses

  2023cites this paper
• Association of the Arabidopsis oleoyl Δ12-desaturase FAD2 with pre-cis-Golgi stacks at endoplasmic reticulum-Golgi-exit sites.

  2023cites this paper
• Genetic and lipidomic analyses reveal the key role of lipid metabolism for cold tolerance in maize.

  2023cites this paper
• Applications and challenges of harnessing genome editing in oilseed crops

  2023cites this paper
• Mapping and identification of QTLs for seed fatty acids in soybean (Glycine max L.)

  2023cites this paper
• Camelina cytosol-localized diacylglycerol acyltransferase 3 contributes to the accumulation of seed storage oils

  2022cites this paper
• Insights into the Novel FAD2 Gene Regulating Oleic Acid Accumulation in Peanut Seeds with Different Maturity

  2022cites this paper
• Efficiency verification of CRISPR–Cas9-mediated mutagenesis of target gene sgRNA using soybean protoplasts

  2022cites this paper
• Genome-Wide Characterization and Expression Analysis of Fatty acid Desaturase Gene Family in Poplar

  2022cites this paper
• The coexpression of two desaturases provides an optimized reduction of saturates in camelina oil

  2022cites this paper
• Natural Variation of Fatty Acid Desaturase Gene Affects Linolenic Acid Content and Starch Pasting Viscosity in Rice Grains

  2022cites this paper
• The genome of Orychophragmus violaceus provides genomic insights into the evolution of Brassicaceae polyploidization and its distinct traits

  2022cites this paper
• Osmotic stress-induced localization switch of CBR1 from mitochondria to the endoplasmic reticulum triggers ATP production via β-oxidation to respond to osmotic shock

  2022cites this paper
• 24-Epibrassinolide Promotes Fatty Acid Accumulation and the Expression of Related Genes in Styrax tonkinensis Seeds

  2022cites this paper
• Novel Allele of FAD2-1A from an EMS-Induced Mutant Soybean Line (PE529) Produces Elevated Levels of Oleic Acid in Soybean Oil

  2022cites this paper
• Comprehensive mining of storage oil related genes in developing seed of Abelmoschus esculentus

  2022cites this paper
• Sequencing of Camelina neglecta, a diploid progenitor of the hexaploid oilseed Camelina sativa

  2022cites this paper
• Linum usitatissimum FUSCA3–1 regulates plant architecture and seed storage reserve accumulation in Arabidopsis thaliana

  2022cites this paper
• Applications and prospects of genome editing in plant fatty acid and triacylglycerol biosynthesis

  2022influential citation
• Molecular Approaches Reduce Saturates and Eliminate trans Fats in Food Oils

  2022influential citation
• Development of a High Oleic Cardoon Cell Culture Platform by SAD Overexpression and RNAi-Mediated FAD2.2 Silencing

  2022cites this paper
• Advances in improvement of soybean seed composition traits using genetic, genomic and biotechnological approaches

  2022cites this paper
• Transcriptomic analysis of high oil-yielding cultivated white sesame and low oil-yielding wild black sesame seeds reveal differentially expressed genes for oil and seed coat colour

  2022cites this paper
• Advances in Understanding the Genetic Basis of Fatty Acids Biosynthesis in Perilla: An Update

  2022cites this paper
• Comparative Analysis and Structural Modeling of Elaeis oleifera FAD2, a Fatty Acid Desaturase Involved in Unsaturated Fatty Acid Composition of American Oil Palm

  2022cites this paper
• Burden tests can be used to map causal genes for a simple metabolic trait in an exome‐sequenced polyploid mutant population

  2022cites this paper
• A single point mutation in a member of FAD2 multigene family resulted in the generation of a high oleic line of Silybum marianum (L.) Gaertn.

  2022cites this paper
• Effect of Overexpression of γ-Tocopherol Methyltransferase on α-Tocopherol and Fatty Acid Accumulation and Tolerance to Salt Stress during Seed Germination in Brassica napus L.

  2022influential citation
• Overexpression mutants reveal a role for a chloroplast MPD protein in regulation of reactive oxygen species during chilling in Arabidopsis.

  2022cites this paper
• CRISPR/Cas9-Mediated Mutagenesis of GmFAD2-1A and/or GmFAD2-1B to Create High-Oleic-Acid Soybean

  2022cites this paper
• GmCDPKSK5 Interacting with GmFAD2-1B Participates in Regulation of Seed Development in Soybean Under High Temperature and Humidity Stress

  2022cites this paper
• The plant lipid metabolic network for assembly of diverse triacylglycerol molecular species

  2022cites this paper
• Crop Quality Improvement Through Genome Editing Strategy

  2022cites this paper
• ABSCISIC ACID-INSENSITIVE 5-ω3 FATTY ACID DESATURASE3 module regulates unsaturated fatty acids biosynthesis in Paeonia ostii.

  2022cites this paper