Development of an LC-MS/MS method for the analysis of Saccharomyces cerevisiae lipidome to determine the mechanism through which plant extract 21 delays aging by remodeling lipid composition

No abstract is available for this paper.

• Publication year

  2017

• Venue

  Unknown venue

• Publication date

  2017-12-19

• Fields of study

  Biology, Medicine, Chemistry, Environmental Science

• Identifiers

  No identifiers available.

• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Mechanisms Underlying the Essential Role of Mitochondrial Membrane Lipids in Yeast Chronological Aging

  2017cited by this paper
• Discovery of plant extracts that greatly delay yeast chronological aging and have different effects on longevity-defining cellular processes

  2016cited by this paper
• Biological Matrix Effects in Quantitative Tandem Mass Spectrometry-Based Analytical Methods: Advancing Biomonitoring

  2016cited by this paper
• Six plant extracts delay yeast chronological aging through different signaling pathways

  2016cited by this paper
• How longevity research can lead to therapies for Alzheimer's disease: The rapamycin story.

  2015cited by this paper
• Lipidomics: analysis of the lipid composition of cells and subcellular organelles by electrospray ionization mass spectrometry.

  2014cited by this paper
• Serine- and Threonine/Valine-Dependent Activation of PDK and Tor Orthologs Converge on Sch9 to Promote Aging

  2014cited by this paper
• Mechanism of liponecrosis, a distinct mode of programmed cell death

  2014influential reference
• A mitochondrially targeted compound delays aging in yeast through a mechanism linking mitochondrial membrane lipid metabolism to mitochondrial redox biology☆

  2014influential reference
• Yeast lipid metabolism at a glance.

  2014cited by this paper
• Stable isotope-assisted lipidomics combined with nontargeted isotopomer filtering, a tool to unravel the complex dynamics of lipid metabolism.

  2013cited by this paper
• The hallmarks of aging.

  2013cited by this paper
• Caloric Restriction: A Key to Understanding and Modulating Aging

  2013cited by this paper
• Role for Two Conserved Intermembrane Space Proteins, Ups1p and Up2p, in Intra-mitochondrial Phospholipid Trafficking*

  2012cited by this paper
• Replicative and chronological aging in Saccharomyces cerevisiae.

  2012cited by this paper
• Metabolism and Regulation of Glycerolipids in the Yeast Saccharomyces cerevisiae

  2012cited by this paper
• Making heads or tails of phospholipids in mitochondria

  2011cited by this paper
• Bottom-up shotgun lipidomics by higher energy collisional dissociation on LTQ Orbitrap mass spectrometers.

  2011cited by this paper
• Shotgun lipidomics on high resolution mass spectrometers.

  2011cited by this paper
• Regulation of phospholipid synthesis in the yeast Saccharomyces cerevisiae.

  2011cited by this paper
• Lessons on longevity from budding yeast

  2010cited by this paper
• Metformin Induces a Dietary Restriction–Like State and the Oxidative Stress Response to Extend C. elegans Healthspan via AMPK, LKB1, and SKN-1

  2010cited by this paper
• Life in the midst of scarcity: adaptations to nutrient availability in Saccharomyces cerevisiae

  2010cited by this paper
• Extending Healthy Life Span—From Yeast to Humans

  2010cited by this paper
• Lipidomics: coming to grips with lipid diversity

  2010influential reference
• Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

  2010cited by this paper
• Converging pathways in lifespan regulation.

  2009cited by this paper
• Rapamycin decelerates cellular senescence

  2009cited by this paper
• Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

  2009cited by this paper
• Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density

  2009cited by this paper
• mTOR signaling at a glance

  2009cited by this paper
• Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis.

  2009cited by this paper
• TOR-driven aging: Speeding car without brakes

  2009cited by this paper
• LKB1 and AMP‐activated protein kinase control of mTOR signalling and growth

  2009cited by this paper
• The role of cardiolipin in the structural organization of mitochondrial membranes.

  2009cited by this paper
• Mitochondrial membrane biogenesis: phospholipids and proteins go hand in hand

  2009cited by this paper
• Cellular functions of cardiolipin in yeast.

  2009cited by this paper
• Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

  2009cited by this paper
• Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry

  2009cited by this paper
• Signaling networks in aging

  2008cited by this paper
• Metformin slows down aging and extends life span of female SHR mice

  2008cited by this paper
• The role of TOR in autophagy regulation from yeast to plants and mammals

  2008cited by this paper
• Aging and survival: the genetics of life span extension by dietary restriction.

  2008cited by this paper
• Aging: ROS or TOR

  2008cited by this paper
• Cardiolipin defines the interactome of the major ADP/ATP carrier protein of the mitochondrial inner membrane

  2008cited by this paper
• Separating cause from effect: how does insulin/IGF signalling control lifespan in worms, flies and mice?

  2008influential reference
• Identification of a lipokine, a lipid hormone linking adipose tissue to systemic metabolism.

  2008cited by this paper
• The early steps of glucose signalling in yeast.

  2008cited by this paper
• Cardiolipin, the heart of mitochondrial metabolism

  2008cited by this paper
• 17 Molecular Mechanisms of Aging: Insights from Budding Yeast

  2008cited by this paper
• FoxO transcription factors in the maintenance of cellular homeostasis during aging.

  2008influential reference
• Yeast Yak1 kinase, a bridge between PKA and stress‐responsive transcription factors, Hsf1 and Msn2/Msn4

  2008cited by this paper
• Caloric restriction mimetics: a novel approach for biogerontology.

  2007cited by this paper
• A signal from inside the peroxisome initiates its division by promoting the remodeling of the peroxisomal membrane

  2007cited by this paper
• Recent Developments in Yeast Aging

  2007influential reference
• MSN2 and MSN4 Link Calorie Restriction and TOR to Sirtuin-Mediated Lifespan Extension in Saccharomyces cerevisiae

  2007cited by this paper
• Role of cardiolipin in cytochrome c release from mitochondria

  2007cited by this paper
• An antidepressant that extends lifespan in adult Caenorhabditis elegans

  2007cited by this paper
• Detection and quantitation of eicosanoids via high performance liquid chromatography-electrospray ionization-mass spectrometry.

  2007cited by this paper
• Endocrine regulation of ageing

  2007cited by this paper
• Inference of transcription modification in long-live yeast strains from their expression profiles

  2007cited by this paper
• Reduced TOR signaling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression.

  2007cited by this paper
• Counting calories in Drosophila diet restriction.

  2007cited by this paper
• Synthesis, storage and degradation of neutral lipids in yeast.

  2007cited by this paper
• Protein Kinase A, TOR, and Glucose Transport Control the Response to Nutrient Repletion in Saccharomyces cerevisiae

  2007cited by this paper
• Significant and Systematic Expression Differentiation in Long-Lived Yeast Strains

  2007cited by this paper
• Life Span Extension by Calorie Restriction Depends on Rim15 and Transcription Factors Downstream of Ras/PKA, Tor, and Sch9

  2007cited by this paper
• Aging and Immortality: Quasi-Programmed Senescence and Its Pharmacologic Inhibition

  2006cited by this paper
• Sirtuins in aging and age-related disease.

  2006cited by this paper
• The trifecta of aging in Caenorhabditis elegans.

  2006cited by this paper
• Sirtuins as potential targets for metabolic syndrome

  2006cited by this paper
• Resveratrol improves health and survival of mice on a high-calorie diet

  2006cited by this paper
• Lipidomics: an analysis of cellular lipids by ESI-MS.

  2006cited by this paper
• Individualization of immunosuppressive therapy. III. Sirolimus associated with a reduced incidence of malignancy.

  2006cited by this paper
• The potential for dietary restriction to increase longevity in humans: extrapolation from monkey studies

  2006cited by this paper
• Glucose Signaling in Saccharomyces cerevisiae

  2006cited by this paper
• Obese Yeast: Triglyceride Lipolysis Is Functionally Conserved from Mammals to Yeast*

  2006cited by this paper
• Cardiolipin metabolism and Barth Syndrome.

  2006cited by this paper
• Extension of chronological life span in yeast by decreased TOR pathway signaling.

  2006cited by this paper
• Calories Do Not Explain Extension of Life Span by Dietary Restriction in Drosophila

  2005cited by this paper
• Toward a unified theory of caloric restriction and longevity regulation.

  2005cited by this paper
• Counting the calories: the role of specific nutrients in extension of life span by food restriction.

  2005cited by this paper
• The Saccharomyces cerevisiae YLL012/YEH1, YLR020/YEH2, and TGL1 Genes Encode a Novel Family of Membrane-Anchored Lipases That Are Required for Steryl Ester Hydrolysis

  2005cited by this paper
• Formation and mobilization of neutral lipids in the yeast Saccharomyces cerevisiae.

  2005cited by this paper
• The expanding TOR signaling network.

  2005cited by this paper
• The plasticity of aging: insights from long-lived mutants.

  2005cited by this paper
• Understanding the odd science of aging.

  2005cited by this paper
• Overview of caloric restriction and ageing.

  2005cited by this paper
• Dynamics of neutral lipid storage in yeast.

  2004cited by this paper
• Sirtuin activators mimic caloric restriction and delay ageing in metazoans

  2004cited by this paper
• PKA and Sch9 control a molecular switch important for the proper adaptation to nutrient availability

  2004cited by this paper
• A fully automated nanoelectrospray tandem mass spectrometric method for analysis of Caco-2 samples.

  2003cited by this paper
• Aberrant cardiolipin metabolism in the yeast taz1 mutant: a model for Barth syndrome

  2003cited by this paper
• The chronological life span of Saccharomyces cerevisiae.

  2003cited by this paper
• Nutritional control of aging.

  2003cited by this paper
• Longevity Regulation in Saccharomyces cerevisiae: Linking Metabolism, Genome Stability, and Heterochromatin

  2003cited by this paper
• Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

  2003cited by this paper
• Towards an e-biology of ageing: integrating theory and data

  2003cited by this paper
• The DGA1 Gene Determines a Second Triglyceride Synthetic Pathway in Yeast*

  2002cited by this paper
• Elucidating TOR Signaling and Rapamycin Action: Lessons from Saccharomyces cerevisiae

  2002cited by this paper

• No citing papers are available for this paper.