Adaptation mechanism of the aspartate receptor: electrostatics of the adaptation subdomain play a key role in modulating kinase activity.

No abstract is available for this paper.

• Publication year

  2005

• Venue

  Biochemistry

• Publication date

  2005-02-08

• Fields of study

  Biology, Medicine, Chemistry

• Identifiers
  DOI 10.1021/BI048089ZPMID 15683239PMCID PMC2896973
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Functional interactions between receptors in bacterial chemotaxis

  2004cited by this paper
• Diversity in Chemotaxis Mechanisms among the Bacteria and Archaea

  2004cited by this paper
• Side chains at the membrane-water interface modulate the signaling state of a transmembrane receptor.

  2004cited by this paper
• Bacterial chemotaxis.

  2003cited by this paper
• Electron Microscopic Analysis of Membrane Assemblies Formed by the Bacterial Chemotaxis Receptor Tsr

  2003cited by this paper
• Dual Recognition of the Bacterial Chemoreceptor by Chemotaxis-specific Domains of the CheR Methyltransferase*

  2002influential reference
• Molecular Information Processing: Lessons from Bacterial Chemotaxis*

  2002cited by this paper
• Collaborative signaling by mixed chemoreceptor teams in Escherichia coli

  2002cited by this paper
• Dynamic and clustering model of bacterial chemotaxis receptors: Structural basis for signaling and high sensitivity

  2002cited by this paper
• Allosteric Enhancement of Adaptational Demethylation by a Carboxyl-terminal Sequence on Chemoreceptors*

  2002cited by this paper
• Sensory rhodopsin II: functional insights from structure.

  2002cited by this paper
• Transmembrane signaling in bacterial chemoreceptors.

  2001cited by this paper
• Polarity in Action: Asymmetric Protein Localization in Bacteria

  2001cited by this paper
• Hydrogen Exchange Reveals a Stable and Expandable Core within the Aspartate Receptor Cytoplasmic Domain*

  2001cited by this paper
• Structure of a conserved receptor domain that regulates kinase activity: the cytoplasmic domain of bacterial taxis receptors.

  2000cited by this paper
• Attractant regulation of the aspartate receptor-kinase complex: limited cooperative interactions between receptors and effects of the receptor modification state.

  2000cited by this paper
• Covalent modification regulates ligand binding to receptor complexes in the chemosensory system of Escherichia coli.

  2000cited by this paper
• Bacterial tactic responses.

  1999cited by this paper
• Signaling domain of the aspartate receptor is a helical hairpin with a localized kinase docking surface: cysteine and disulfide scanning studies.

  1999cited by this paper
• Identification of a site critical for kinase regulation on the central processing unit (CPU) helix of the aspartate receptor.

  1999cited by this paper
• The aspartate receptor cytoplasmic domain: in situ chemical analysis of structure, mechanism and dynamics.

  1999cited by this paper
• Four-helical-bundle structure of the cytoplasmic domain of a serine chemotaxis receptor

  1999influential reference
• Detection of a Conserved α-Helix in the Kinase-docking Region of the Aspartate Receptor by Cysteine and Disulfide Scanning*

  1998cited by this paper
• Cysteine and disulfide scanning reveals two amphiphilic helices in the linker region of the aspartate chemoreceptor.

  1998cited by this paper
• The two-component signaling pathway of bacterial chemotaxis: a molecular view of signal transduction by receptors, kinases, and adaptation enzymes.

  1997cited by this paper
• Cysteine and Disulfide Scanning Reveals a Regulatory α-Helix in the Cytoplasmic Domain of the Aspartate Receptor*

  1997cited by this paper
• Detecting the conformational change of transmembrane signaling in a bacterial chemoreceptor by measuring effects on disulfide cross-linking in vivo.

  1996cited by this paper
• The receptor binding site for the methyltransferase of bacterial chemotaxis is distinct from the sites of methylation.

  1996cited by this paper
• Molecular mechanism of transmembrane signaling by the aspartate receptor: a model.

  1996cited by this paper
• Molecular evolution of the C-terminal cytoplasmic domain of a superfamily of bacterial receptors involved in taxis.

  1996influential reference
• Classical electrostatics in biology and chemistry.

  1995cited by this paper
• Lock On/Off Disulfides Identify the Transmembrane Signaling Helix of the Aspartate Receptor (*)

  1995cited by this paper
• Three-dimensional structures of the ligand-binding domain of the bacterial aspartate receptor with and without a ligand.

  1995cited by this paper
• Transmembrane signaling by the aspartate receptor: engineered disulfides reveal static regions of the subunit interface.

  1995cited by this paper
• Deducing the organization of a transmembrane domain by disulfide cross-linking. The bacterial chemoreceptor Trg.

  1994cited by this paper
• Structure and dynamics of Escherichia coli chemosensory receptors. Engineered sulfhydryl studies.

  1992cited by this paper
• Attenuation of sensory receptor signaling by covalent modification.

  1992cited by this paper
• Reconstitution of the bacterial chemotaxis signal transduction system from purified components.

  1991cited by this paper
• Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons

  1991influential reference
• Efficient site-directed mutagenesis using uracil-containing DNA.

  1991cited by this paper
• Role of CheW protein in coupling membrane receptors to the intracellular signaling system of bacterial chemotaxis.

  1989influential reference
• Analysis of mutations in the transmembrane region of the aspartate chemoreceptor in Escherichia coli.

  1986cited by this paper
• Kinetics of receptor modification. The multiply methylated aspartate receptors involved in bacterial chemotaxis.

  1986influential reference
• Surface structure recognized for covalent modification of the aspartate receptor in chemotaxis.

  1986influential reference
• Chemotaxis in Bacteria

  1966cited by this paper

• A chemoreceptor conformational equilibrium controlled by signaling inputs

  2025influential citation
• Bacterial chemoreceptors transmit stimulus signals through coupled entropic switches.

  2025cites this paper
• Chemoreceptors in Sinorhizobium meliloti require minimal pentapeptide tethers to provide adaptational assistance

  2024cites this paper
• The structural logic of dynamic signaling in the Escherichia coli serine chemoreceptor

  2024cites this paper
• The Structural Logic of Dynamic Signaling in the Escherichia coli Serine Chemoreceptor

  2024cites this paper
• Structural signatures of Escherichia coli chemoreceptor signaling states revealed by cellular crosslinking

  2022cites this paper
• Concerted Differential Changes of Helical Dynamics and Packing upon Ligand Occupancy in a Bacterial Chemoreceptor.

  2021cites this paper
• Methyltransferase CheR binds to its chemoreceptor substrates independent of their signaling conformation yet modifies them differentially

  2020cites this paper
• In Situ Conformational Changes of the Escherichia coli Serine Chemoreceptor in Different Signaling States

  2019cites this paper
• Conformational shifts in a chemoreceptor helical hairpin control kinase signaling in Escherichia coli

  2019cites this paper
• Paradoxical enhancement of chemoreceptor detection sensitivity by a sensory adaptation enzyme

  2017cites this paper
• The torments of the cohesin ring

  2017cites this paper
• Bacterial Chemoreceptor Dynamics: Helical Stability in the Cytoplasmic Domain Varies with Functional Segment and Adaptational Modification.

  2016cites this paper
• Signaling and sensory adaptation in Escherichia coli chemoreceptors: 2015 update.

  2015cites this paper
• Bacterial chemoreceptor dynamics correlate with activity state and are coupled over long distances

  2015cites this paper
• Lessons in Fundamental Mechanisms and Diverse Adaptations from the 1 2015 BLAST ( Bacterial Locomotion and Signal Transduction ) Meeting 2 3

  2015cites this paper
• Preformed Soluble Chemoreceptor Trimers That Mimic Cellular Assembly States and Activate CheA Autophosphorylation

  2015cites this paper
• Lessons in Fundamental Mechanisms and Diverse Adaptations from the 2015 Bacterial Locomotion and Signal Transduction Meeting

  2015cites this paper
• Signaling and Adaptation Modulate the Dynamics of the Photosensoric Complex of Natronomonas pharaonis

  2015cites this paper
• Bacterial chemoreceptors and chemoeffectors

  2014cites this paper
• Hydrogen Exchange Differences between Chemoreceptor Signaling Complexes Localize to Functionally Important Subdomains

  2014cites this paper
• HAMP domain structural determinants for signalling and sensory adaptation in Tsr, the Escherichia coli serine chemoreceptor

  2014cites this paper
• Architecture and signal transduction mechanism of the bacterial chemosensory array: progress, controversies, and challenges.

  2014cites this paper
• Comparative Genomics of Microbial Chemoreceptor Sequence, Structure, and Function

  2014cites this paper
• Axial helix rotation as a mechanism for signal regulation inferred from the crystallographic analysis of the E. coli serine chemoreceptor.

  2014cites this paper
• Membrane association of a protein increases the rate, extent, and specificity of chemical cross-linking.

  2013cites this paper
• Excitation and Adaptation in Bacteria–a Model Signal Transduction System that Controls Taxis and Spatial Pattern Formation

  2013cites this paper
• HAMP Domain Conformers That Propagate Opposite Signals in Bacterial Chemoreceptors

  2013cites this paper
• An Unorthodox Sensory Adaptation Site in the Escherichia coli Serine Chemoreceptor

  2013cites this paper
• Structure, function, and on-off switching of a core unit contact between CheA kinase and CheW adaptor protein in the bacterial chemosensory array: A disulfide mapping and mutagenesis study.

  2013cites this paper
• 15 Bacterial Behavior

  2013cites this paper
• Application of Computational Molecular Biophysics to Problems in Bacterial Chemotaxis

  2013cites this paper
• Functional and structural effects of seven‐residue deletions on the coiled‐coil cytoplasmic domain of a chemoreceptor

  2012cites this paper
• A 'trimer of Dimers'-based Model for the Chemotactic Signal Transduction Network in Bacterial Chemotaxis

  2012cites this paper
• A “Trimer of Dimers”—Based Model for the Chemotactic Signal Transduction Network in Bacterial Chemotaxis

  2012cites this paper
• Structural and Functional Studies of the Bacterial Chemoreceptor, EBV’s LMP-1, and S. cerevisiae’s Kar3Cik1

  2012influential citation
• Characterization of Chemosensing in the Alphaproteobacterium Azospirillum brasilense

  2012cites this paper
• Mutational Analysis of the Control Cable That Mediates Transmembrane Signaling in the Escherichia coli Serine Chemoreceptor

  2011cites this paper
• Site-specific methylation in Bacillus subtilis chemotaxis: effect of covalent modifications to the chemotaxis receptor McpB

  2011cites this paper
• Biphasic control logic of HAMP domain signalling in the Escherichia coli serine chemoreceptor

  2011cites this paper
• A possible degree of motional freedom in bacterial chemoreceptor cytoplasmic domains and its potential role in signal transduction.

  2011cites this paper
• Functional and structural effects of seven-residue deletions on the coiled-coil cytoplasmic domain of a chemoreceptormmi

  2011cites this paper
• Mutational Analysis of the Control Cable That Mediates Transmembrane Signaling in the <named-content content-type='genus-species' xlink:type='simple'>Escherichia coli</named-content> Serine Chemoreceptor

  2011cites this paper
• Signaling mechanisms of HAMP domains in chemoreceptors and sensor kinases.

  2010cites this paper
• Thermosensing Function of the Escherichia coli Redox Sensor Aer

  2010cites this paper
• Signaling Mechanisms of HAMP Domains in Chemoreceptors

  2010cites this paper
• Chapter 11. Transmembrane Signaling

  2010cites this paper
• Mutational analyses of HAMP helices suggest a dynamic bundle model of input–output signalling in chemoreceptors

  2009influential citation
• Engineered socket study of signaling through a four-helix bundle: evidence for a yin-yang mechanism in the kinase control module of the aspartate receptor.

  2009cites this paper
• THE ROLE OF THE TM 2-HAMP JUNCTION IN CONTROL OF THE SIGNALING STATE OF THE ASPARTATE CHEMORECEPTOR

  2009cites this paper
• The core signaling proteins of bacterial chemotaxis assemble to form an ultrastable complex.

  2009cites this paper
• The role of protein-membrane interactions in modulation of signaling by bacterial chemoreceptors

  2009cites this paper
• Signal processing within and between bacterial chemoreceptors

  2009cites this paper
• The structure of a soluble chemoreceptor suggests a mechanism for propagating conformational signals.

  2009cites this paper
• The molecular basis of excitation and adaptation during chemotactic sensory transduction in bacteria.

  2009cites this paper
• The region preceding the C-terminal NWETF pentapeptide modulates baseline activity and aspartate inhibition of Escherichia coli Tar.

  2008cites this paper
• Capturing the VirA/VirG TCS of Agrobacterium tumefaciens.

  2008cites this paper
• Bacterial chemoreceptors: high-performance signaling in networked arrays.

  2008influential citation
• Role of HAMP domains in chemotaxis signaling by bacterial chemoreceptors

  2008cites this paper
• Use of site-directed cysteine and disulfide chemistry to probe protein structure and dynamics: applications to soluble and transmembrane receptors of bacterial chemotaxis.

  2007cites this paper
• Evolutionary genomics reveals conserved structural determinants of signaling and adaptation in microbial chemoreceptors

  2007cites this paper
• Integration of Rotation and Piston Motions in Coiled-Coil Signal Transduction

  2007cites this paper
• Ancient chemoreceptors retain their flexibility

  2007cites this paper
• Intradimer and interdimer methylation response by bacterial chemoreceptors to attractant stimulus

  2007cites this paper
• Phenotypic suppression methods for analyzing intra- and inter-molecular signaling interactions of chemoreceptors.

  2007cites this paper
• Structure of the conserved HAMP domain in an intact, membrane-bound chemoreceptor: a disulfide mapping study.

  2007cites this paper
• Differential effects of chemoreceptor methylation‐domain mutations on swarming and development in the social bacterium Myxococcus xanthus

  2006cites this paper
• 12 Reversible methylation of glutamate residues in the receptor proteins of bacterial sensory systems.

  2006cites this paper
• Reconstruction of the chemotaxis receptor–kinase assembly

  2006cites this paper
• Tuning a bacterial chemoreceptor with protein-membrane interactions.

  2006cites this paper
• Conserved glycine residues in the cytoplasmic domain of the aspartate receptor play essential roles in kinase coupling and on-off switching.

  2005cites this paper
• Evidence that the adaptation region of the aspartate receptor is a dynamic four-helix bundle: cysteine and disulfide scanning studies.

  2005cites this paper