EUK-8 and EUK-134 reduce serum glucose and lipids and ameliorate streptozotocin-induced oxidative damage in the pancreas, liver, kidneys, and brain tissues of diabetic rats

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Medicinal Chemistry Research

• Publication date

  2012-10-01

• Fields of study

  Medicine, Chemistry, Environmental Science

• Identifiers
  DOI 10.1007/s00044-011-9855-2
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Antidiabetic effect of Punica granatum flowers: effect on hyperlipidemia, pancreatic cells lipid peroxidation and antioxidant enzymes in experimental diabetes.

  2009cited by this paper
• Nasturtium officinale reduces oxidative stress and enhances antioxidant capacity in hypercholesterolaemic rats.

  2008cited by this paper
• Cardiovascular Diabetology BioMed Central Review

  2006cited by this paper
• Rutin improves the antioxidant status in streptozotocin-induced diabetic rat tissues

  2006cited by this paper
• Effect of mangiferin on hyperglycemia and atherogenicity in streptozotocin diabetic rats.

  2005cited by this paper
• Effects of repaglinide on oxidative stress in tissues of diabetic rabbits.

  2005cited by this paper
• Glutathione metabolism and its implications for health.

  2004cited by this paper
• Oxidative stress and gene expression of antioxidant enzymes in the renal cortex of streptozotocin-induced diabetic rats

  2004cited by this paper
• New insights on oxidative stress and diabetic complications may lead to a "causal" antioxidant therapy.

  2003cited by this paper
• Modification of renal oxidative stress and lipid peroxidation in streptozotocin-induced diabetic rats treated with extracts from Gongronema latifolium leaves.

  2003cited by this paper
• Oxidation of nitric oxide by oxomanganese-salen complexes: a new mechanism for cellular protection by superoxide dismutase/catalase mimetics.

  2002cited by this paper
• Attenuating CV risk factors in patients with diabetes: clinical evidence to clinical practice

  2002cited by this paper
• An aldose reductase inhibitor reverses early diabetes‐induced changes in peripheral nerve function, metabolism, and antioxidative defense

  2002cited by this paper
• Alterations in antioxidant enzymes and oxidative damage in experimental diabetic rat tissues: Effect of vanadate and fenugreek (Trigonella foenum graecum)

  2002cited by this paper
• The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas.

  2001cited by this paper
• The role of nitric oxide in the development of streptozotocin-induced diabetes mellitus: experimental and clinical implications.

  2000cited by this paper
• The potential role of nitric oxide in the hypertrophic growth of the left ventricle.

  2000cited by this paper
• EUK-134, a synthetic superoxide dismutase and catalase mimetic, prevents oxidative stress and attenuates kainate-induced neuropathology.

  1999cited by this paper
• Fundamental Aspects of Reactive Oxygen Species, or What's the Matter with Oxygen?

  1999cited by this paper
• Lipid peroxidation and antioxidant status in experimental diabetes.

  1999cited by this paper
• Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells

  1997cited by this paper
• Low antioxidant enzyme gene expression in pancreatic islets compared with various other mouse tissues.

  1996cited by this paper
• Nitric oxide is released in regenerating liver after partial hepatectomy

  1995cited by this paper
• EUK-8, a synthetic superoxide dismutase and catalase mimetic, ameliorates acute lung injury in endotoxemic swine.

  1995cited by this paper
• Autoimmune Diabetes Induced by the β-cell Toxin STZ: Immunity to the 60-kDa Heat Shock Protein and to Insulin

  1994cited by this paper
• Salen-manganese complexes are superoxide dismutase-mimics.

  1993cited by this paper
• Plasma malondialdehyde in type 1 and type 2 diabetic patients.

  1993cited by this paper
• Altered kinetic attributes of Na(+)+K(+)-ATPase activity in kidney, brain and erythrocyte membranes in alloxan-diabetic rats.

  1992cited by this paper
• Increased degradation of dermal collagen in diabetic rats.

  1991cited by this paper
• Improvement of hyperglycemia and hyperlipemia in streptozotocin-diabetic rats by a methanolic extract of Prunus davidiana stems and its main component, prunin.

  1991cited by this paper
• Malondialdehyde determination as index of lipid peroxidation.

  1990cited by this paper
• Free radicals and diabetes.

  1988cited by this paper
• Glucose autoxidation and protein modification. The potential role of 'autoxidative glycosylation' in diabetes.

  1987cited by this paper
• Alterations in Free Radical Tissue-Defense Mechanisms in Streptozocin-Induced Diabetes in Rat: Effects of Insulin Treatment

  1987cited by this paper
• Catalase in vitro.

  1984cited by this paper
• A modified spectrophotometric assay of superoxide dismutase.

  1984cited by this paper
• Dosage effect of streptozotocin on rat tissue enzyme activities and glycogen concentration.

  1982cited by this paper
• Morphologic abnormalities observed in retina, pancreas and kidney of diabetic Chinese hamsters

  1974cited by this paper
• Bromobenzene-induced liver necrosis. Protective role of glutathione and evidence for 3,4-bromobenzene oxide as the hepatotoxic metabolite.

  1974cited by this paper
• Manganese Schiff's base complexes—I: Synthesis and spectroscopy of some anion complexes of (4-sec-butylsalicylaldehydeethylenediiminato) manganese(III)

  1973cited by this paper
• Protein measurement with the Folin phenol reagent.

  1951cited by this paper
• Molecular Sciences Antioxidant Protective Effect of Glibenclamide and Metformin in Combination with Honey in Pancreas of Streptozotocin- Induced Diabetic Rats

  year unknowncited by this paper

• Methyl jasmonate protects liver and pancreas tissues of adult diabetic rats from STZ-induced oxidative stress damage.

  2026cites this paper
• Effect of green synthesized silver nanoparticles using the aqueous extract of Lavandula angustifolia Mill. against ethanol-induced gastric ulcers in rats

  2025cites this paper
• Investigation of the Effect of Pyrogallol on the Formation of Amylin Amyloid Fibrils as a Strategy for the Treatment of Type 2 Diabetic Patients: A Theoretical and Experimental Study

  2023cites this paper
• Silver nanoparticles synthesized from Quercus brantii ameliorated ethanol-induced gastric ulcers in rats by decreasing oxidative stress and improving antioxidant systems

  2023cites this paper
• Evaluation of antioxidant and anti-ulcerogenic effects of Eremurus persicus (Jaub & Spach) Boiss leaf hydroalcoholic extract on ethanol-induced gastric ulcer in rats

  2021cites this paper
• Geraniol ameliorated serum lipid profile and improved antioxidant defense system in pancreas, liver and heart tissues of alloxan-induced diabetic rats

  2021cites this paper
• Geraniol ameliorated serum lipid profile and improved antioxidant defense system in pancreas, liver and heart tissues of alloxan-induced diabetic rats

  2021cites this paper
• Ameliorating and protective effects mesalazine on ethanol-induced gastric ulcers in experimental rats.

  2020cites this paper
• Modulation of the antioxidant defense system in liver, kidney, and pancreas tissues of alloxan-induced diabetic rats by camphor.

  2020cites this paper
• Salen‑manganese complexes for controlling ROS damage: Neuroprotective effects, antioxidant activity and kinetic studies.

  2019cites this paper
• Pitfalls in the ABTS Peroxidase Activity Test: Interference of Photochemical Processes.

  2018cites this paper
• Water exchange reaction of a manganese catalase mimic: oxygen-17 NMR relaxometry study on (aqua)manganese(III) in a salen scaffold and its reactions in a mildly basic medium

  2016cites this paper
• Free Radical Scavenging Activity and Neuroprotective Potentials of D138, One Cu(II)/Zn(II) Schiff-Base Complex Derived from N,N′-bis(2-Hydroxynaphthylmethylidene)-1,3-propanediamine

  2014cites this paper