Tumorigenicity of the miR-17-92 cluster distilled.

No abstract is available for this paper.

• Publication year

  2010

• Venue

  Genes & Development

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1101/gad.1887110PMID 20047995PMCID PMC2802185
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• miR-19 is a key oncogenic component of mir-17-92.

  2009influential reference
• Genetic dissection of the miR-17~92 cluster of microRNAs in Myc-induced B-cell lymphomas.

  2009influential reference
• Aberrant regulation of pVHL levels by microRNA promotes the HIF/VEGF axis in CLL B cells.

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