Semaphorins and their receptors in immune cell interactions

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Nature Immunology

• Publication date

  Unknown publication date

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1038/ni1553PMID 18087252
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Regulation of T-cell activation by the cytoskeleton

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• Semaphorin 7A plays a critical role in TGF-β1–induced pulmonary fibrosis

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• Semaphorin 7A initiates T-cell-mediated inflammatory responses through alpha1beta1 integrin.

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• Semaphorin‐4A, an activator for T‐cell‐mediated immunity, suppresses angiogenesis via Plexin‐D1

  2007cited by this paper
• Immune semaphorins: increasing members and their diverse roles.

  2007cited by this paper
• Getting to the site of inflammation: the leukocyte adhesion cascade updated

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• Semaphorin 7A initiates T-cell-mediated inflammatory responses through α1β1 integrin

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• Semaphorin 7A is a negative regulator of T cell responses.

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• T Cell, Ig Domain, Mucin Domain-2 Gene-Deficient Mice Reveal a Novel Mechanism for the Regulation of Th2 Immune Responses and Airway Inflammation1

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• Semaphorin-3A is expressed by tumor cells and alters T-cell signal transduction and function.

  2006cited by this paper
• Plexin C1 Engagement on Mouse Dendritic Cells by Viral Semaphorin A39R Induces Actin Cytoskeleton Rearrangement and Inhibits Integrin-Mediated Adhesion and Chemokine-Induced Migration

  2005cited by this paper
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  2005cited by this paper
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• Semaphorins command cells to move

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• Requirement for CD100-CD72 interactions in fine-tuning of B-cell antigen receptor signaling and homeostatic maintenance of the B-cell compartment.

  2005cited by this paper
• Nonredundant roles of Sema4A in the immune system: defective T cell priming and Th1/Th2 regulation in Sema4A-deficient mice.

  2005cited by this paper
• Soluble CD100 functions on human monocytes and immature dendritic cells require plexin C1 and plexin B1, respectively.

  2005cited by this paper
• The Semaphorin 4D Receptor Plexin-B1 Is a GTPase Activating Protein for R-Ras

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• The role of very late antigen-1 in immune-mediated inflammation.

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• Guidance of myocardial patterning in cardiac development by Sema6D reverse signalling

  2004cited by this paper
• The collagen binding alpha1beta1 integrin VLA-1 regulates CD8 T cell-mediated immune protection against heterologous influenza infection.

  2004cited by this paper
• Requirement of Rac1 and Rac2 Expression by Mature Dendritic Cells for T Cell Priming

  2004cited by this paper
• PlexinD1 and semaphorin signaling are required in endothelial cells for cardiovascular development.

  2004cited by this paper
• The Collagen Binding α1β1 Integrin VLA-1 Regulates CD8 T Cell-Mediated Immune Protection against Heterologous Influenza Infection

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• In vivo imaging of leukocyte trafficking in blood vessels and tissues.

  2004cited by this paper
• Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2.

  2004cited by this paper
• Role of the cytoskeleton during leukocyte responses

  2004cited by this paper
• CD 40 Expression by Human Monocytes : Regulation by Cytokines and Activation of Monocytes by the Ligand for CD 40

  2003cited by this paper
• Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function

  2003cited by this paper
• Semaphorin 7A promotes axon outgrowth through integrins and MAPKs

  2003cited by this paper
• CIITA-regulated plexin-A1 affects T-cell–dendritic cell interactions

  2003cited by this paper
• Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development.

  2003cited by this paper
• Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses.

  2003cited by this paper
• Semaphorin junction: making tracks toward neural connectivity.

  2003cited by this paper
• TREMs in the immune system and beyond

  2003cited by this paper
• CD100/Plexin-B1 interactions sustain proliferation and survival of normal and leukemic CD5+ B lymphocytes.

  2003cited by this paper
• Expression and functional importance of collagen-binding integrins, alpha 1 beta 1 and alpha 2 beta 1, on virus-activated T cells.

  2003cited by this paper
• Human Semaphorin 3B (SEMA3B) located at chromosome 3p21.3 suppresses tumor formation in an adenocarcinoma cell line.

  2002cited by this paper
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  2002cited by this paper
• Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology.

  2002cited by this paper
• Requirement for the Lymphocyte Semaphorin, CD100, in the Induction of Antigen-Specific T Cells and the Maturation of Dendritic Cells1

  2002cited by this paper
• Integrins: bidirectional, allosteric signaling machines.

  2002cited by this paper
• Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2

  2002cited by this paper
• Sema7A is a Potent Monocyte Stimulator

  2002cited by this paper
• Semaphorin 3F gene from human 3p21.3 suppresses tumor formation in nude mice.

  2002cited by this paper
• Regulation of B cell fates by BCR signaling components.

  2002cited by this paper
• Enhanced Immune Responses in Transgenic Mice Expressing a Truncated Form of the Lymphocyte Semaphorin CD1001

  2001cited by this paper
• The SH2 Domain Containing Tyrosine Phosphatase-1 Down-regulates Activation of Lyn and Lyn-induced Tyrosine Phosphorylation of the CD19 Receptor in B Cells*

  2001cited by this paper
• SHP-1 Requires Inhibitory Co-receptors to Down-modulate B Cell Antigen Receptor-mediated Phosphorylation of Cellular Substrates*

  2001cited by this paper
• Biological Activity of Soluble CD100. II. Soluble CD100, Similarly to H-SemaIII, Inhibits Immune Cell Migration1 2

  2001cited by this paper
• Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B

  2001cited by this paper
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  2000cited by this paper
• Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling.

  2000cited by this paper
• CDw108 expression during T-cell development.

  2000cited by this paper
• The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice.

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• A novel transcription factor, T-bet, directs Th1 lineage commitment.

  2000cited by this paper
• Shared resources between the neural and immune systems: semaphorins join the ranks.

  1999cited by this paper
• Molecular cloning of a glycosylphosphatidylinositol-anchored molecule CDw108.

  1999cited by this paper
• CD72-deficient mice reveal nonredundant roles of CD72 in B cell development and activation.

  1999cited by this paper
• Unified nomenclature for the semaphorins/collapsins [1]

  1999cited by this paper
• Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

  1999cited by this paper
• Unified nomenclature for the semaphorins/collapsins. Semaphorin Nomenclature Committee.

  1999cited by this paper
• Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.

  1999cited by this paper
• The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation.

  1998cited by this paper
• The B-cell transmembrane protein CD72 binds to and is an in vivo substrate of the protein tyrosine phosphatase SHP-1.

  1998cited by this paper
• Human Semaphorin K1 Is Glycosylphosphatidylinositol-linked and Defines a New Subfamily of Viral-related Semaphorins*

  1998cited by this paper
• CD100 is a leukocyte semaphorin

  1998cited by this paper
• A poxvirus-encoded semaphorin induces cytokine production from monocytes and binds to a novel cellular semaphorin receptor, VESPR.

  1998cited by this paper
• Neuropilin is a receptor for the axonal chemorepellent Semaphorin III.

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  1997cited by this paper
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  1996cited by this paper
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  1996cited by this paper
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• CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice.

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• From form to function: signaling by protein tyrosine phosphatases.

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• Immunobiology: The Immune System in Health and Disease

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• A role in B cell activation for CD22 and the protein tyrosine phosphatase SHP.

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  1993cited by this paper
• The semaphorin genes encode a family of transmembrane and secreted growth cone guidance molecules.

  1993cited by this paper
• The immune system in health and disease.

  1992cited by this paper
• Increased surface expression of a newly identified 150-kDa dimer early after human T lymphocyte activation.

  1992cited by this paper
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  1990cited by this paper

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