Association of annexin A2 with cancer development (Review).

No abstract is available for this paper.

• Publication year

  2015

• Venue

  Oncology Report

• Publication date

  2015-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.3892/or.2015.3837PMID 25760910
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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• Coexpression of ANXA2, SOD2 and HOXA13 predicts poor prognosis of esophageal squamous cell carcinoma.

  2014cited by this paper
• Prognostic and diagnostic significance of annexin A2 in colorectal cancer

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• Identification of annexin II as a novel secretory biomarker for breast cancer

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• Protein interactions between surface annexin A2 and S100A10 mediate adhesion of breast cancer cells to microvascular endothelial cells

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• Annexin A2 is not a good biomarker for hepatocellular carcinoma in cirrhosis

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• Prognostic significance of annexin II expression in non-small cell lung cancer

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• Annexin A2 Promotes the Migration and Invasion of Human Hepatocellular Carcinoma Cells In Vitro by Regulating the Shedding of CD147-Harboring Microvesicles from Tumor Cells

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• Annexin A2 is regulated by ovarian cancer-peritoneal cell interactions and promotes metastasis

  2013influential reference
• Annexin A1, A2, A4 and A5 play important roles in breast cancer, pancreatic cancer and laryngeal carcinoma, alone and/or synergistically.

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• Annexin A2 silencing inhibits invasion, migration, and tumorigenic potential of hepatoma cells.

  2013influential reference
• Clinical significance of annexin II expression in human non-small cell lung cancer

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• Proteomics‐based analysis of invasion‐related proteins in malignant gliomas

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• Actin Stabilization by Jasplakinolide Affects the Function of Bone Marrow-Derived Late Endothelial Progenitor Cells

  2012cited by this paper
• Genotoxic Agents Promote the Nuclear Accumulation of Annexin A2: Role of Annexin A2 in Mitigating DNA Damage

  2012cited by this paper
• Upregulated expression of Annexin II is a prognostic marker for patients with gastric cancer

  2012cited by this paper
• The hallmarks of cancer

  2012cited by this paper
• Expression characteristics and diagnostic value of annexin A2 in hepatocellular carcinoma.

  2012influential reference
• Reciprocal Regulation of Annexin A2 and EGFR with Her-2 in Her-2 Negative and Herceptin-Resistant Breast Cancer

  2012cited by this paper
• Effect of shRNA Mediated Down-Regulation of Annexin A2 on Biological Behavior of Human Lung Adencarcinoma Cells A549

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• Annexin A2 at the Interface of Actin and Membrane Dynamics: A Focus on Its Roles in Endocytosis and Cell Polarization

  2012cited by this paper
• Endothelial precursor cells promote angiogenesis in hepatocellular carcinoma.

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• Proteomic analysis of oxidative modification in endothelial colony-forming cells treated by hydrogen peroxide.

  2012cited by this paper
• Akt/mTOR signaling pathway is crucial for gemcitabine resistance induced by Annexin II in pancreatic cancer cells.

  2012cited by this paper
• Annexin A2 Silencing Induces G2 Arrest of Non-small Cell Lung Cancer Cells through p53-dependent and -independent Mechanisms*

  2012influential reference
• Antibody-directed neutralization of annexin II (ANX II) inhibits neoangiogenesis and human breast tumor growth in a xenograft model.

  2012cited by this paper
• Up‐regulation of Anxa2 gene promotes proliferation and invasion of breast cancer MCF‐7 cells

  2012cited by this paper
• Annexin A2 mediates up-regulation of NF-κB, β-catenin, and stem cell in response to progastrin in mice and HEK-293 cells.

  2011cited by this paper
• HDAC6 regulates aggresome‐autophagy degradation pathway of α‐synuclein in response to MPP+‐induced stress

  2011cited by this paper
• The Role of Annexin A2 in Tumorigenesis and Cancer Progression

  2011cited by this paper
• Annexin A2 is a novel Cellular Redox Regulatory Protein involved in Tumorigenesis

  2011cited by this paper
• A competitive hexapeptide inhibitor of annexin A2 prevents hypoxia-induced angiogenic events

  2011cited by this paper
• Proteomic identification of differentially-expressed proteins in esophageal cancer in three ethnic groups in Xinjiang

  2011cited by this paper
• Tyrosine 23 Phosphorylation-Dependent Cell-Surface Localization of Annexin A2 Is Required for Invasion and Metastases of Pancreatic Cancer

  2011cited by this paper
• Hallmarks of cancer: the next generation.

  2011cited by this paper
• The role of the annexin A2 heterotetramer in vascular fibrinolysis.

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• Annexin 2 Regulates Endothelial Morphogenesis by Controlling AKT Activation and Junctional Integrity*

  2010cited by this paper
• Breast cancer cell surface annexin II induces cell migration and neoangiogenesis via tPA dependent plasmin generation.

  2010cited by this paper
• Mechanism of endothelial progenitor cell recruitment into neo-vessels in adjacent non-tumor tissues in hepatocellular carcinoma

  2010cited by this paper
• Silencing of the annexin II gene down-regulates the levels of S100A10, c-Myc, and plasmin and inhibits breast cancer cell proliferation and invasion.

  2010cited by this paper
• Agents that bind annexin A2 suppress ocular neovascularization

  2010cited by this paper
• Signal transducer and activator of transcription 6 (STAT6) is a novel interactor of annexin A2 in prostate cancer cells.

  2010cited by this paper
• Annexin II promotes invasion and migration of human hepatocellular carcinoma cells in vitro via its interaction with HAb18G/CD147

  2010cited by this paper
• Homocysteine inhibits neoangiogenesis in mice through blockade of annexin A2-dependent fibrinolysis.

  2009cited by this paper
• Evaluation of annexin II as a potential serum marker for hepatocellular carcinoma using a developed sandwich ELISA method.

  2009influential reference
• Annexins in human breast cancer: Possible predictors of pathological response to neoadjuvant chemotherapy.

  2009cited by this paper
• Identification of metastasis associated proteins in human lung squamous carcinoma using two-dimensional difference gel electrophoresis and laser capture microdissection.

  2009cited by this paper
• Annexin A2 Binding to Endosomes and Functions in Endosomal Transport Are Regulated by Tyrosine 23 Phosphorylation*

  2009cited by this paper
• S100A6 binds to annexin 2 in pancreatic cancer cells and promotes pancreatic cancer cell motility

  2009cited by this paper
• Vascular endothelial growth factor upregulates expression of annexin A2 in vitro and in a mouse model of ischemic retinopathy

  2009cited by this paper
• Anxa2 plays a critical role in enhanced invasiveness of the multidrug resistant human breast cancer cells.

  2009cited by this paper
• Annexin II represents metastatic potential in clear-cell renal cell carcinoma

  2009cited by this paper
• Annexin A2-dependent polymerization of actin mediates endosome biogenesis.

  2009cited by this paper
• Overexpression of Annexin II affects the proliferation, apoptosis, invasion and production of proangiogenic factors in multiple myeloma

  2009cited by this paper
• Annexin II Overexpression Predicts Rapid Recurrence after Surgery in Pancreatic Cancer Patients Undergoing Gemcitabine-Adjuvant Chemotherapy

  2008cited by this paper
• Involvement of Annexin A2 in p53 induced apoptosis in lung cancer

  2008cited by this paper
• Annexin A2 localizes to the basal epithelial layer and is down-regulated in dysplasia and head and neck squamous cell carcinoma.

  2008cited by this paper
• Epstein–Barr virus latent membrane protein 1 mediates serine 25 phosphorylation and nuclear entry of annexin A2 via PI‐PLC–PKCα/PKCβ pathway

  2008cited by this paper
• The role of adherens junctions and VE-cadherin in the control of vascular permeability

  2008cited by this paper
• Annexin II Overexpression Predicts Rapid Recurrence after Surgery in Pancreatic Cancer Patients Undergoing Gemcitabine-Adjuvant Chemotherapy

  2008cited by this paper
• Annexin II/Annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer

  2008cited by this paper
• Annexin A2 Phosphorylation Mediates Cell Scattering and Branching Morphogenesis via Cofilin Activation

  2007cited by this paper
• Antiapoptotic effects of progastrin on pancreatic cancer cells are mediated by sustained activation of nuclear factor-{kappa}B.

  2007cited by this paper
• Characterisation and protein expression profiling of annexins in colorectal cancer

  2007cited by this paper
• The mRNA-binding site of annexin A2 resides in helices C-D of its domain IV.

  2007cited by this paper
• The role of annexin II in angiogenesis and tumor progression: a potential therapeutic target.

  2007cited by this paper
• Proteome analysis and tissue microarray for profiling protein markers associated with lymph node metastasis in colorectal cancer.

  2007cited by this paper
• Regulation of nucleo-cytoplasmic shuttling of human annexin A2—a proposed mechanism

  2007cited by this paper
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• Knockdown of annexin 2 decreases migration of human glioma cells in vitro

  2006influential reference
• Direct comparison of umbilical cord blood versus bone marrow-derived endothelial precursor cells in mediating neovascularization in response to vascular ischemia.

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• Annexin A2 recognises a specific region in the 3'-UTR of its cognate messenger RNA.

  2006cited by this paper
• Angiogenesis-associated protein annexin II in breast cancer: selective expression in invasive breast cancer and contribution to tumor invasion and progression.

  2006influential reference
• Regulation of actin dynamics by annexin 2

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• Involvement of the Annexin II-S100A10 Complex in the Formation of E-cadherin-based Adherens Junctions in Madin-Darby Canine Kidney Cells*

  2005cited by this paper
• Annexins and Ca2+ handling in the heart.

  2005cited by this paper
• Annexin A2 binds to the localization signal in the 3′ untranslated region of c‐myc mRNA

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• Annexins: linking Ca2+ signalling to membrane dynamics

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• Annexin A2 Is a Novel RNA-binding Protein

  2004cited by this paper
• An Annexin 2 Phosphorylation Switch Mediates p11-dependent Translocation of Annexin 2 to the Cell Surface*

  2004cited by this paper
• The co-workers of actin filaments: from cell structures to signals

  2004cited by this paper
• Annexin 2 is a phosphatidylinositol (4,5)-bisphosphate binding protein recruited to actin assembly sites at cellular membranes

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• Annexins – unique membrane binding proteins with diverse functions

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  2003cited by this paper
• Cellular motility driven by assembly and disassembly of actin filaments.

  2003cited by this paper
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  2003cited by this paper
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• The c-MYC oncoprotein as a treatment target in cancer and other disorders of cell growth

  2003cited by this paper
• Plasminogen binding and cancer: promises and pitfalls.

  2003cited by this paper
• Angiogenesis in health and disease

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• Plasmin-induced Migration of Endothelial Cells

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• Tissue plasminogen activator is required for the growth, invasion, and angiogenesis of pancreatic tumor cells.

  2002cited by this paper
• Epithelial–mesenchymal transitions in tumour progression

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• A molecular compendium of genes expressed in multiple myeloma.

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• Annexins: from structure to function.

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• The Plasminogen Activator Inhibitor PAI-1 Controls in Vivo Tumor Vascularization by Interaction with Proteases, Not Vitronectin

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• Annexin II overexpression is correlated with poor prognosis in human gastric carcinoma.

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• SPOCK1 promotes the progression of breast cancer by modulating cancer-associated fibroblasts and exerts a synergistic effect with ANXA2

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• S100 A16 promotes the progression of osteosarcoma by activating the PI3 K/AKT signaling pathway through ANXA2

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• Annexin, a Protein for All Seasons: From Calcium Dependent Membrane Metabolism to RNA Recognition

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• HLF is a promising prognostic, immunological, and therapeutic biomarker in human tumors

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• Annexin A2: the feasibility of being a therapeutic target associated with cancer metastasis and drug resistance in cancer microenvironment

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• Annexin A2 in Tumors of the Gastrointestinal Tract, Liver, and Pancreas

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• Impact of Annexin A2 on virus life cycles

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• The novel DNA methylation marker FIBIN suppresses non-small cell lung cancer metastasis by negatively regulating ANXA2.

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• Multi-Omics Profiling Identifies Microglial Annexin A2 as a Key Mediator of NF-κB Pro-inflammatory Signaling in Ischemic Reperfusion Injury

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• FGF19 promotes nasopharyngeal carcinoma progression by inducing angiogenesis via inhibiting TRIM21-mediated ANXA2 ubiquitination

  2023cites this paper
• The proteomics analysis of extracellular vesicles revealed the possible function of heat shock protein 60 in Helicobacter pylori infection

  2023cites this paper
• The flavagline FL3 interferes with the association of Annexin A2 with the eIF4F initiation complex and transiently stimulates the translation of annexin A2 mRNA

  2023influential citation
• Annexin A protein family: Focusing on the occurrence, progression and treatment of cancer

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• ANXA2 is a potential biomarker for cancer prognosis and immune infiltration: A systematic pan-cancer analysis

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• Annexin A2: The diversity of pathological effects in tumorigenesis and immune response

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  2022cites this paper
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  2020cites this paper
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  2020cites this paper
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