Diffusion kurtosis as an in vivo imaging marker for reactive astrogliosis in traumatic brain injury

No abstract is available for this paper.

• Publication year

  2012

• Venue

  NeuroImage

• Publication date

  2012-01-02

• Fields of study

  Medicine, Computer Science

• Identifiers
  DOI 10.1016/j.neuroimage.2011.07.050PMID 21835250PMCID PMC3614502
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Traumatic brain injury.

  2013cited by this paper
• MRI evaluation of axonal reorganization after bone marrow stromal cell treatment of traumatic brain injury

  2011cited by this paper
• More accurate estimation of diffusion tensor parameters using diffusion kurtosis imaging

  2011cited by this paper
• New Imaging Captures the Brainʼs Complexity

  2010cited by this paper
• MRI quantification of non‐Gaussian water diffusion by kurtosis analysis

  2010cited by this paper
• q‐space and conventional diffusion imaging of axon and myelin damage in the rat spinal cord after axotomy

  2010cited by this paper
• Diffusion Kurtosis Imaging ( DKI ) Reconstruction-Linear or Non-Linear ?

  2010cited by this paper
• MR diffusion kurtosis imaging for neural tissue characterization

  2010influential reference
• A prospective diffusion tensor imaging study in mild traumatic brain injury

  2010cited by this paper
• Non-Gaussian Analysis of Diffusion-Weighted MR Imaging in Head and Neck Squamous Cell Carcinoma: A Feasibility Study

  2010cited by this paper
• Cerebral gliomas: diffusional kurtosis imaging analysis of microstructural differences.

  2010influential reference
• Voxel-Based Analysis of Diffusion Tensor Imaging in Mild Traumatic Brain Injury in Adolescents

  2010cited by this paper
• Distinct MRI pattern in lesional and perilesional area after traumatic brain injury in rat--11 months follow-up.

  2009cited by this paper
• Astrocytes: biology and pathology

  2009influential reference
• Molecular dissection of reactive astrogliosis and glial scar formation.

  2009influential reference
• Does diffusion kurtosis imaging lead to better neural tissue characterization? A rodent brain maturation study

  2009cited by this paper
• Multi-exponential signal decay from diffusion in a single compartment.

  2009cited by this paper
• Opposing Roles for Reactive Astrocytes following Traumatic Brain Injury

  2008cited by this paper
• Moderate and severe traumatic brain injury in adults.

  2008cited by this paper
• Age‐related non‐Gaussian diffusion patterns in the prefrontal brain

  2008cited by this paper
• Biexponential analysis of diffusion-related signal decay in normal human cortical and deep gray matter.

  2008cited by this paper
• Diffusion tensor imaging of acute mild traumatic brain injury in adolescents

  2008cited by this paper
• Towards better MR characterization of neural tissues using directional diffusion kurtosis analysis

  2008cited by this paper
• Diffusion tensor imaging during recovery from severe traumatic brain injury and relation to clinical outcome: a longitudinal study.

  2008cited by this paper
• Extent of Microstructural White Matter Injury in Postconcussive Syndrome Correlates with Impaired Cognitive Reaction Time: A 3T Diffusion Tensor Imaging Study of Mild Traumatic Brain Injury

  2008cited by this paper
• Diffusion Tensor Imaging Reliably Detects Experimental Traumatic Axonal Injury and Indicates Approximate Time of Injury

  2007cited by this paper
• Detection of traumatic axonal injury with diffusion tensor imaging in a mouse model of traumatic brain injury.

  2007influential reference
• Diffusion tensor imaging of the brain

  2007cited by this paper
• Is the “biexponential diffusion” biexponential?

  2007cited by this paper
• White matter integrity and cognition in chronic traumatic brain injury: a diffusion tensor imaging study.

  2007cited by this paper
• Analysis of acute traumatic axonal injury using diffusion tensor imaging

  2007cited by this paper
• Diffusion Tensor Imaging Detects Clinically Important Axonal Damage after Mild Traumatic Brain Injury: A Pilot Study

  2007influential reference
• Diffusional kurtosis imaging in the lung using hyperpolarized 3He

  2006cited by this paper
• The Epidemiology and Impact of Traumatic Brain Injury: A Brief Overview

  2006cited by this paper
• Essential protective roles of reactive astrocytes in traumatic brain injury.

  2006cited by this paper
• Three‐dimensional characterization of non‐gaussian water diffusion in humans using diffusion kurtosis imaging

  2006influential reference
• Physiologic progesterone reduces mitochondrial dysfunction and hippocampal cell loss after traumatic brain injury in female rats.

  2006cited by this paper
• Spatial and temporal characteristics of neurodegeneration after controlled cortical impact in mice: more than a focal brain injury.

  2005cited by this paper
• Diffusional kurtosis imaging: The quantification of non‐gaussian water diffusion by means of magnetic resonance imaging

  2005influential reference
• Whole-brain apparent diffusion coefficient in traumatic brain injury: correlation with Glasgow Coma Scale score.

  2004cited by this paper
• Time course of cellular pathology after controlled cortical impact injury.

  2003influential reference
• Astrocytes and Brain Injury

  2003cited by this paper
• Neurons, glia, and plasticity in normal brain aging.

  2003cited by this paper
• Combination of single-voxel proton MR spectroscopy and apparent diffusion coefficient calculation in the evaluation of common brain tumors.

  2003cited by this paper
• Diffusion tensor imaging detects and differentiates axon and myelin degeneration in mouse optic nerve after retinal ischemia

  2003cited by this paper
• Lymphomas and high-grade astrocytomas: comparison of water diffusibility and histologic characteristics.

  2002cited by this paper
• High b‐value q‐space analyzed diffusion‐weighted MRS and MRI in neuronal tissues – a technical review

  2002cited by this paper
• Normal brain and brain tumor: multicomponent apparent diffusion coefficient line scan imaging.

  2001cited by this paper
• Magnetisation transfer ratio and mean diffusivity of normal appearing white and grey matter from patients with multiple sclerosis

  2001cited by this paper
• Assignment of the water slow‐diffusing component in the central nervous system using q‐space diffusion MRS: Implications for fiber tract imaging

  2000cited by this paper
• Readout: Diffusion-tensor MR Imaging of the Human

  2000cited by this paper
• Anisotropy of water diffusion in corona radiata and cerebral peduncle in patients with hemiparesis.

  1999cited by this paper
• Multi‐component apparent diffusion coefficients in human brain †

  1999cited by this paper
• An evaluation of the time dependence of the anisotropy of the water diffusion tensor in acute human ischemia.

  1999cited by this paper
• Diffusion anisotropy measurements in ischaemic stroke of the human brain

  1998cited by this paper
• Non-mono-exponential attenuation of water and N-acetyl aspartate signals due to diffusion in brain tissue.

  1998cited by this paper
• Clinical utility of diffusion‐weighted magnetic resonance imaging in the assessment of ischemic stroke

  1997cited by this paper
• Diffusion tensor MR imaging of the human brain.

  1996cited by this paper
• Biexponential diffusion attenuation in various states of brain tissue: Implications for diffusion‐weighted imaging

  1996cited by this paper
• AFNI: software for analysis and visualization of functional magnetic resonance neuroimages.

  1996cited by this paper
• Controlling the false discovery rate: a practical and powerful approach to multiple testing

  1995influential reference
• Acute human stroke studied by whole brain echo planar diffusion‐weighted magnetic resonance imaging

  1995cited by this paper
• A controlled cortical impact model of traumatic brain injury in the rat.

  1991cited by this paper
• Statistical Power Analysis for the Behavioral Sciences (2nd ed.)

  1989influential reference
• Neocortical cell counts in normal human adult aging

  1987cited by this paper
• The Rat Brain in Stereotaxic Coordinates

  1983influential reference
• AChE-stained horizontal sections of the rat brain in stereotaxic coordinates.

  1980cited by this paper
• Magnetic Resonance in Medicine 51:321–330 (2004) Biexponential Diffusion Tensor Analysis of Human Brain Diffusion Data

  year unknowncited by this paper
• NeuroImage

  year unknowncited by this paper

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