Cytotoxic peptides from the marine sponge Cymbastela sp.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Tetrahedron

• Publication date

  1995-09-25

• Fields of study

  Chemistry, Environmental Science

• Identifiers
  DOI 10.1016/0040-4020(95)00646-P
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar

• No claims are published for this paper.

• No concepts are published for this paper.

• Hemiasterlin and geodiamolide TA; two new cytotoxic peptides from the marine sponge Hemiasterella minor (Kirkpatrick)

  1994cited by this paper
• Milnamide A, an unusual cytotoxic tripeptide from the marine sponge Auletta cf. constricta

  1994cited by this paper
• Bioactive Sponge Peptides

  1993cited by this paper
• Geodiamolides C to F, new cytotoxic cyclodepsipeptides from the marine sponge Pseudaxinyssa sp.

  1990cited by this paper
• Stereostructures of geodiamolides A and B, novel cyclodepsipeptides from the marine sponge Geodia sp

  1987cited by this paper
• Jaspamide, a modified peptide from a Jaspis sponge, with insecticidal and antifungal activity.

  1986cited by this paper
• Jasplakinolide, a cyclodepsipeptide from the marine sponge, Jaspis SP.

  1986cited by this paper
• Determination ofD-amino acids. II. Use of a bifunctional reagent, 1,5-difluoro-2,4-dinitrobenzene

  1984cited by this paper
• N-Methylamino Acids in Peptide Synthesis. II. A New Synthesis of N-Benzyloxycarbonyl, N-Methylamino Acids

  1973cited by this paper

• Recent Advances in Marine-Derived Nanoformulation for the Management of Glioblastoma

  2024cites this paper
• An Updated Review on Recent Advances in the Usage of Novel Therapeutic Peptides for Breast Cancer Treatment

  2023cites this paper
• Marine life as a source for breast cancer treatment: A comprehensive review.

  2023cites this paper
• Therapeutic potential of marine peptides in cervical and ovarian cancers

  2021cites this paper
• Promising Activities of Marine Natural Products against Hematopoietic Malignancies

  2021cites this paper
• Therapeutic potential of marine peptides in glioblastoma: Mechanistic insights.

  2021cites this paper
• Applications of ultrasound in total synthesis of bioactive natural products: A promising green tool

  2021cites this paper
• Expeditious Total Synthesis of Hemiasterlin through a Convergent Multicomponent Strategy and Its Use in Targeted Cancer Therapeutics

  2020cites this paper
• Cytotoxic and Antitumor Compounds from Marine Invertebrates

  2020cites this paper
• Organo-Halogens and their Possible Involvement in Prebiotic Chemistry

  2020cites this paper
• Marine anticancer drugs and their relevant targets: a treasure from the ocean

  2019cites this paper
• New Acyclic Cytotoxic Jasplakinolide Derivative from the Marine Sponge Jaspis splendens

  2019cites this paper
• Natural Products from Sponges

  2019cites this paper
• Marine natural product peptides with therapeutic potential: Chemistry, biosynthesis, and pharmacology.

  2018cites this paper
• Biotechnological Applications of Bioactive Peptides From Marine Sources.

  2018cites this paper
• A Maldiisotopic Approach to Discover Natural Products: Cryptomaldamide, a Hybrid Tripeptide from the Marine Cyanobacterium Moorea producens.

  2017cites this paper
• Synthesis of new hemiasterlin derivatives with α,β-unsaturated carbonyl-thiophene groups in fragment A

  2017cites this paper
• Total Synthesis of the Marine Natural Product Hemiasterlin by Organocatalyzed α-Hydrazination.

  2017cites this paper
• Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.

  2017cites this paper
• Sponging off nature for new drug leads.

  2017cites this paper
• Oceans: Abode of Nutraceuticals, Pharmaceuticals, and Biotoxins

  2017cites this paper
• Chemopreventive role of food-derived proteins and peptides: A review

  2017cites this paper
• A theoretical study on synthesis mechanisms of α,β-unsaturated carbon γ-amino ester catalyzed by PPh3

  2017cites this paper
• Marine-Derived Fungal Metabolites

  2015cites this paper
• Divergent solid-phase synthesis of natural product-inspired bipartite cyclodepsipeptides: total synthesis of seragamide A.

  2015cites this paper
• The Travails of Clinical Trials with Marine-­Sourced Compounds

  2015cites this paper
• Simple indole alkaloids and those with a nonrearranged monoterpenoid unit.

  2015cites this paper
• Probing the Physicochemical Boundaries of Cell Permeability and Oral Bioavailability in Lipophilic Macrocycles Inspired by Natural Products.

  2015cites this paper
• Chapter 6 – Applied potential and current applications of alkaloids

  2015cites this paper
• Stereoselective Syntheses of α,β-Unsaturated γ-Amino Esters Through Phosphine-Catalyzed γ-Umpolung Additions of Sulfonamides to γ-Substituted Allenoates.

  2015cites this paper
• Porifera (Sponges)–1

  2014cites this paper
• Synthesis of new bioisosteric hemiasterlin analogues with extremely high cytotoxicity.

  2014cites this paper
• Porifera (Sponges)–5

  2014cites this paper
• Apoptosis inducing lead compounds isolated from marine organisms of potential relevance in cancer treatment.

  2014cites this paper
• Synthesis of new simplified hemiasterlin derivatives with α,β-unsaturated carbonyl moiety.

  2014cites this paper
• Potent Cytotoxic Peptides from the Australian Marine Sponge Pipestela candelabra

  2014influential citation
• Natural product chemistry and anticancer drug discovery

  2014cites this paper
• Hemiasterlin analogues incorporating an aromatic, and heterocyclic type C-terminus: design, synthesis and biological evaluation

  2014cites this paper
• Porifera (Sponges)–2

  2014cites this paper
• Naturally occurring organoiodines

  2014cites this paper
• Marine Invertebrate Natural Products for Anti-Inflammatory and Chronic Diseases

  2013cites this paper
• N‐Methylierung von Peptiden und Proteinen: ein wichtiges Element für die Regulation biologischer Funktionen

  2013cites this paper
• L-Phototryptophan: L-Phototryptophan

  2013cites this paper
• Self-assembly to function: design, synthesis, and broad spectrum antimicrobial properties of short hybrid E-vinylogous lipopeptides.

  2013cites this paper
• Structural Characteristics of Bioactive Marine Natural Products

  2013cites this paper
• INFORMATIC STRATEGIES AND TECHNOLOGIES FOR THE DIRECTED DISCOVERY OF NONRIBOSOMAL PEPTIDES

  2013cites this paper
• Marine Peptides and Proteins with Cytotoxic and Antitumoral Properties

  2013cites this paper
• N-methylation of peptides and proteins: an important element for modulating biological functions.

  2013cites this paper
• The Chemistry of Marine Sponges∗

  2012influential citation
• Pipestelides A-C: cyclodepsipeptides from the Pacific marine sponge Pipestela candelabra.

  2012cites this paper
• Marine natural products.

  2012cites this paper
• Bioactive Natural Products from Papua New Guinea Marine Sponges

  2012cites this paper
• Hybrid peptides: direct transformation of α/α, β-unsaturated γ-hybrid peptides to α/γ-hybrid peptide 12-helices.

  2012cites this paper
• A phase 1 trial of E7974 administered on day 1 of a 21‐day cycle in patients with advanced solid tumors

  2012cites this paper
• Bioactive marine peptides: nutraceutical value and novel approaches.

  2012cites this paper
• Marine Natural Products That Target Microtubules

  2012cites this paper
• Bioassay guided fractionation for the isolation of cytotoxic compounds from a Caribbean marine sponge

  2011cites this paper
• Synthesis of α, β-unsaturated γ-amino esters with unprecedented high (E)-stereoselectivity and their conformational analysis in peptides.

  2011cites this paper
• Synthesis and structural investigations of functionalizable hybrid β-hairpin.

  2011cites this paper
• Marine Organisms and Their Prospective Use in Therapy of Human Diseases

  2011cites this paper
• The Dolastatins: Novel Antitumor Agents from Dolabella auricularia

  2011cites this paper
• A Journey Under the Sea: The Quest for Marine Anti-Cancer Alkaloids

  2011cites this paper
• Preparation of α-amino acids by oxidative oxazoline-oxazinone rearrangement-hydrogenation (OOOH). Scope and limitations.

  2011cites this paper
• Nonprotein l-Amino Acids

  2010cites this paper
• Recent progress in the chemistry of non-monoterpenoid indole alkaloids

  2010cites this paper
• Marine invertebrates: Sponges

  2010cites this paper
• Highly diastereoselective total synthesis of the anti-tumoral agent (±)-Spisulosine (ES285) from a Morita–Baylis–Hillman adduct

  2010cites this paper
• Absolute configurations of tubulin inhibitors taltobulin (HTI-286) and HTI-042 characterized by X-ray diffraction analysis and NMR studies.

  2010cites this paper
• Synthesis and structure-activity correlation of natural-product inspired cyclodepsipeptides stabilizing F-actin.

  2010cites this paper
• Organocatalytic asymmetric synthesis of (−)-δ-coniceine based on sequential proline-catalyzed asymmetric α-amination–HWE olefination

  2010cites this paper
• Marine Natural Products and their Synthetic Derivatives for Cancer Therapy

  2010cites this paper
• Versatile synthesis of new cytotoxic agents structurally related to hemiasterlins.

  2010cites this paper
• Natural guanidine derivatives.

  2010cites this paper
• Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin

  2009influential citation
• Drug development from marine natural products

  2009cites this paper
• Hemiasterlin Analogues with Unnatural Amino Acids at the N-Terminal and Their Inhibitory Activity on Tumor Cells

  2009cites this paper
• Palladium-catalyzed insertion of alpha-diazoesters into vinyl halides to generate alpha,beta-unsaturated gamma-amino esters.

  2009cites this paper
• Jaspamides M–P: new tryptophan modified jaspamide derivatives from the sponge Jaspis splendans

  2009cites this paper
• Jaspamides H–L, new actin-targeting depsipeptides from the sponge Jaspis splendans

  2008cites this paper
• Destabilizing Agents: Peptides and Depsipeptides

  2008cites this paper
• CHAPTER 5 – Natural product chemistry and anticancer drug discovery

  2008cites this paper
• Identification of the Eight-Membered Heterocycles Hicksoanes A-C from the Gorgonian Subergorgia hicksoni

  2008cites this paper
• Microtubule Targeting Agents

  2007cites this paper
• Structure–activity and High‐content Imaging Analyses of Novel Tubulysins

  2007cites this paper
• New jaspamide derivatives with antimicrofilament activity from the sponge Jaspis splendans

  2007cites this paper
• Biogenic Iodine and Iodine-Containing Metabolites

  2006cites this paper
• Antitubulin agents for the treatment of cancer – a medicinal chemistry update

  2006cites this paper
• Tetra and Pentapeptide Derivatives of Hemiasterlin. Synthesis and Activity Studies

  2006cites this paper
• Cytoskeleton alterations induced by Geodia corticostylifera depsipeptides in breast cancer cells.

  2006cites this paper
• Natural neo acids and neo alkanes: Their analogs and derivatives

  2006cites this paper
• Chemistry and Biology of Novel Microtubule-Destabilizing Agents that Bind α-Tubulin

  2006cites this paper
• Molecular and biochemical studies of chondramide formation-highly cytotoxic natural products from Chondromyces crocatus Cm c5.

  2006cites this paper
• α-Trialkylsilyl Amino Acid Stability

  2005cites this paper
• Natural products to drugs: natural product-derived compounds in clinical trials.

  2005cites this paper
• The Discovery of Anticancer Drugs From Natural Sources

  2005cites this paper
• Koshikamide A2, a Cytotoxic Linear Undecapeptide Isolated from a Marine Sponge of Theonella sp.

  2005cites this paper
• HTI-286, A Synthetic Analog of the Antimitotic Natural Product Hemiasterlin

  2005cites this paper
• The marine bromotyrosine derivatives.

  2005cites this paper
• D-piece modifications of the hemiasterlin analog HTI-286 produce potent tubulin inhibitors.

  2004cites this paper
• Enantioselective total synthesis of (+)-milnamide A and evidence of its autoxidation to (+)-milnamide D.

  2004cites this paper