Endogenous RNA interference provides a somatic defense against Drosophila transposons.

No abstract is available for this paper.

• Publication year

  2008

• Venue

  Current Biology

• Publication date

  2008-06-03

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1016/j.cub.2008.05.006PMID 18501606PMCID PMC2812477
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• An endogenous small interfering RNA pathway in Drosophila

  2008cited by this paper
• The regulatory activity of microRNA* species has substantial influence on microRNA and 3′ UTR evolution

  2008cited by this paper
• Endogenous siRNAs Derived from Transposons and mRNAs in Drosophila Somatic Cells

  2008cited by this paper
• Endogenous siRNAs from naturally formed dsRNAs regulate transcripts in mouse oocytes

  2008cited by this paper
• Two distinct mechanisms generate endogenous siRNAs from bidirectional transcription in Drosophila melanogaster

  2008cited by this paper
• The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members

  2008cited by this paper
• Drosophila endogenous small RNAs bind to Argonaute 2 in somatic cells

  2008cited by this paper
• The Drosophila hairpin RNA pathway generates endogenous short interfering RNAs

  2008cited by this paper
• Pseudogene-derived small interfering RNAs regulate gene expression in mouse oocytes

  2008cited by this paper
• Amplification of the 1731 LTR retrotransposon in Drosophila melanogaster cultured cells: origin of neocopies and impact on the genome.

  2007cited by this paper
• Antiviral immunity directed by small RNAs.

  2007cited by this paper
• Discrete small RNA-generating loci as master regulators of transposon activity in Drosophila.

  2007cited by this paper
• The UCSC Genome Browser Database: 2008 update

  2007cited by this paper
• Pimet, the Drosophila homolog of HEN1, mediates 2'-O-methylation of Piwi- interacting RNAs at their 3' ends.

  2007cited by this paper
• Suffix-specific RNAi Leads to Silencing of F Element in Drosophila melanogaster

  2007cited by this paper
• The Piwi-piRNA Pathway Provides an Adaptive Defense in the Transposon Arms Race

  2007cited by this paper
• The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila.

  2007cited by this paper
• Critical roles for Dicer in the female germline.

  2007cited by this paper
• Sorting of Drosophila small silencing RNAs.

  2007cited by this paper
• Drosophila microRNAs are sorted into functionally distinct argonaute complexes after production by dicer-1.

  2007cited by this paper
• The Drosophila RNA methyltransferase, DmHen1, modifies germline piRNAs and single-stranded siRNAs in RISC.

  2007cited by this paper
• A Distinct Small RNA Pathway Silences Selfish Genetic Elements in the Germline

  2006cited by this paper
• L1 retrotransposition is suppressed by endogenously encoded small interfering RNAs in human cultured cells

  2006cited by this paper
• A Novel Repeat-Associated Small Interfering RNA-Mediated Silencing Pathway Downregulates Complementary Sense gypsy Transcripts in Somatic Cells of the Drosophila Ovary

  2006cited by this paper
• Genome-Wide Analysis of mRNAs Regulated by Drosha and Argonaute Proteins in Drosophila melanogaster

  2006cited by this paper
• Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes.

  2006cited by this paper
• Normal microRNA Maturation and Germ-Line Stem Cell Maintenance Requires Loquacious, a Double-Stranded RNA-Binding Domain Protein

  2005cited by this paper
• Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways.

  2004cited by this paper
• Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways.

  2004cited by this paper
• Evidence for De Novo rearrangements of Drosophila transposable elements induced by the passage to the cell culture

  2004cited by this paper
• Transposon silencing in the Caenorhabditis elegans germ line by natural RNAi

  2003cited by this paper
• ARGONAUTE1 is required for efficient RNA interference in Drosophila embryos

  2002cited by this paper
• An Abundant Class of Tiny RNAs with Probable Regulatory Roles in Caenorhabditis elegans

  2001cited by this paper
• Developmental roles and molecular characterization of a Drosophila homologue of Arabidopsis Argonaute1, the founder of a novel gene superfamily

  2001cited by this paper
• Mut-7 of C. elegans, required for transposon silencing and RNA interference, is a homolog of Werner syndrome helicase and RNaseD.

  1999cited by this paper
• Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

  1998cited by this paper
• Double-stranded sequences in RNA of Drosophila melanogaster: relation to mobile dispersed genes.

  1980cited by this paper
• Transposition of elements of the 412, copia and 297 dispersed repeated gene families in Drosophila.

  1979cited by this paper
• Repeated gene families in Drosophila melanogaster.

  1978cited by this paper

• Recurrent expansion and rapid evolution of the Drosophilid RNAi pathway in testis

  2025cites this paper
• Abundant A-to-I RNA editing in spermatocytes may suppress transposons to compensate for piRNA downregulation in male germlines

  2025cites this paper
• Apprehending siRNA Machinery and Gene Silencing in Brinjal Shoot and Fruit Borer, Leucinodes orbonalis.

  2025cites this paper
• A guide to the biogenesis and functions of endogenous small non-coding RNAs in animals

  2025cites this paper
• Dynamics and evolution of transposable elements in mosquito genomes.

  2025cites this paper
• An endogenous retroviral element co-opts an upstream regulatory sequence to achieve somatic expression and mobility

  2025cites this paper
• Structural basis of endo-siRNA processing by Drosophila Dicer-2 and Loqs-PD

  2025cites this paper
• Insights into the target-directed miRNA degradation mechanism in Drosophila ovarian cell culture.

  2025cites this paper
• AGO2 slicing of a domesticated retrotransposon is necessary for normal vasculature development

  2025cites this paper
• Unexplored power of CRISPR-Cas9 in neuroscience, a multi-OMICs review.

  2024cites this paper
• RNA Interference in Insects: From a Natural Mechanism of Gene Expression Regulation to a Biotechnological Crop Protection Promise

  2024cites this paper
• Regulation of Retrotransposons in Drosophila melanogaster Somatic Tissues

  2024cites this paper
• A low-abundance class of Dicer-dependent siRNAs produced from a variety of features in C. elegans

  2024cites this paper
• Intricate interactions between antiviral immunity and transposable element control in Drosophila

  2024cites this paper
• Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti

  2024cites this paper
• The Complex Landscape of Structural Divergence Between the Drosophila pseudoobscura and D. persimilis Genomes

  2024cites this paper
• Experimentally evolving Drosophila erecta populations may fail to establish an effective piRNA-based host defense against invading P-elements

  2024cites this paper
• Regulation of Uni-Strand and Dual-Strand piRNA Clusters in Germ and Somatic Tissues in Drosophila melanogaster under Control of rhino

  2023cites this paper
• Amniotes co-opt intrinsic genetic instability to protect germ-line genome integrity

  2023cites this paper
• Knockdown of Dcr1 and Dcr2 limits the lethal effect of C-factor in Chilo suppressalis.

  2023cites this paper
• Essential and recurrent roles for hairpin RNAs in silencing de novo sex chromosome conflict in Drosophila simulans

  2023cites this paper
• Evidence of target-mediated miRNA degradation in Drosophila ovarian cell culture

  2023cites this paper
• P-element invasions in Drosophila erecta shed light on the establishment of host control over a transposable element

  2022cites this paper
• Endogenous RNAi silences a burgeoning sex chromosome arms race

  2022cites this paper
• Transposon control as a checkpoint for tissue regeneration.

  2022cites this paper
• Tumor elimination by clustered microRNAs miR-306 and miR-79 via noncanonical activation of JNK signaling

  2022cites this paper
• Artificially stimulating retrotransposon activity increases mortality and accelerates a subset of aging phenotypes in Drosophila

  2022cites this paper
• Generalized nuclear localization of retroelement transcripts

  2022cites this paper
• Invading viral DNA triggers dsRNA synthesis by RNA polymerase II to activate antiviral RNA interference in Drosophila.

  2022cites this paper
• The Intricate Evolutionary Balance between Transposable Elements and Their Host: Who Will Kick at Goal and Convert the Next Try?

  2022cites this paper
• The Tudor Domain-Containing Protein, Kotsubu (CG9925), Localizes to the Nuage and Functions in piRNA Biogenesis in D. melanogaster

  2022cites this paper
• Opinion: Genetic Conflict With Mobile Elements Drives Eukaryotic Genome Evolution, and Perhaps Also Eukaryogenesis.

  2021cites this paper
• The Chromosomal Distribution of Sex-Biased MicroRNAs in Drosophila is Nonadaptive

  2021cites this paper
• Unraveling the features of somatic transposition in the Drosophila intestine

  2021cites this paper
• Ago2 protects Drosophila siRNAs and microRNAs from target-directed degradation, even in the absence of 2′-O-methylation

  2021cites this paper
• Evolution of genome structure in the Drosophila simulans species complex

  2020cites this paper
• Somatic transposition in the Drosophila intestine occurs in active chromatin and is associated with tumor suppressor gene inactivation

  2020cites this paper
• Viral infection impacts transposable element transcript amounts in Drosophila

  2020cites this paper
• Dicer’s Helicase Domain: A Meeting Place for Regulatory Proteins

  2020cites this paper
• AGO unchained: Canonical and non-canonical roles of Argonaute proteins in mammals.

  2020cites this paper
• RNA interference dynamics in juvenile Fasciola hepatica are altered during in vitro growth and development

  2020cites this paper
• The nuclear export of siRNA precursors via the dsRBD protein Blanks in Drosophila melanogaster

  2020cites this paper
• Run or Die in the Evolution of New MicroRNAs—Testing the Red Queen Hypothesis on De Novo New Genes

  2020cites this paper
• In vitro studies provide insight into effects of Dicer-2 helicase mutations in Drosophila melanogaster

  2020cites this paper
• Impacts of sex ratio meiotic drive on genome structure and defense in a stalk-eyed fly

  2020cites this paper
• RNAi and miRNA pathways in arthropods

  2020cites this paper
• Viral Infection and Stress Affect Protein Levels of Dicer 2 and Argonaute 2 in Drosophila melanogaster

  2020cites this paper
• Caractérisation des interactions entre les défenses antivirales et le contrôle génomique des éléments transposables chez Drosophila

  2019influential citation
• Functional divergence of thyrotropin beta-subunit paralogs gives new insights into salmon smoltification metamorphosis

  2019cites this paper
• Har-P, a short P-element variant, weaponizes P-transposase to severely impair Drosophila development

  2019cites this paper
• The role of transposable elements activity in aging and their possible involvement in laminopathic diseases.

  2019cites this paper
• Etude de la biologie des clusters de piRNAs chez Drosophila melanogaster en utilisant comme modèle le locus flamenco

  2019cites this paper
• The role of small and long non-coding RNAs in cardiac pathologies

  2019cites this paper
• Small RNA proteome as disease biomarker: An incognito treasure of clinical utility

  2019cites this paper
• Sensing Viral Infections in Insects: A Dearth of Pathway Receptors.

  2019cites this paper
• Cellular labeling of endogenous retrovirus replication (CLEVR) reveals de novo insertions of the gypsy retrotransposable element in cell culture and in both neurons and glial cells of aging fruit flies

  2019cites this paper
• Antiviral RNAi in Insects and Mammals: Parallels and Differences

  2019cites this paper
• Crosstalk Between Mammalian Antiviral Pathways

  2019cites this paper
• The hpRNA/RNAi Pathway Is Essential to Resolve Intragenomic Conflict in the Drosophila Male Germline.

  2018cites this paper
• The somatic piRNA pathway controls germline transposition over generations

  2018cites this paper
• Diverse RNA interference strategies in early-branching metazoans

  2018cites this paper
• Topoisomerase 3β interacts with RNAi machinery to promote heterochromatin formation and transcriptional silencing in Drosophila

  2018cites this paper
• Exploring RNA interference in the agricultural pests western corn rootworm, fall armyworm, and southern green stink bug

  2018cites this paper
• The genome of the Hi5 germ cell line from Trichoplusia ni, an agricultural pest and novel model for small RNA biology

  2018cites this paper
• Regulation of Large Number of Weak Targets—New Insights from Twin-microRNAs

  2018cites this paper
• Cellular labeling of endogenous virus replication (CLEVR) reveals de novo insertions of the gypsy endogenous retrovirus in cell culture and in both neurons and glial cells of aging fruit flies

  2018cites this paper
• The Retrotransposon storm and the dangers of a Collyer's genome.

  2018cites this paper
• A Transgenic Flock House Virus Replicon Reveals an RNAi Independent Antiviral Mechanism Acting in Drosophila Follicular Somatic Cells

  2018cites this paper
• Explorer Quantifying Adaptive Evolution in the Drosophila Immune System

  2017cites this paper
• Pervasive Behavioral Effects of MicroRNA Regulation in Drosophila

  2017influential citation
• Small Non‐Coding RNAS in Gametogenesis

  2017cites this paper
• Insulin/insulin-like growth factor-1 signalling (IIS) based regulation of lifespan across species

  2017cites this paper
• Transepithelial delivery of macromolecular biopesticides

  2017cites this paper
• Re-Arrangements in the Cytoplasmic Distribution of Small RNAs Following the Maternal-to-Zygotic Transition in Drosophila Embryos

  2017cites this paper
• Structural Foundations of RNA Silencing by Argonaute.

  2017cites this paper
• Loquacious-PD facilitates Drosophila Dicer-2 cleavage through interactions with the helicase domain and dsRNA

  2017cites this paper
• Molecular basis for asymmetry sensing of siRNAs by the Drosophila Loqs-PD/Dcr-2 complex in RNA interference

  2017cites this paper
• Massive Expansion of Gypsy-Like Retrotransposons in Microbotryum Fungi

  2017cites this paper
• Literature review of baseline information to support the risk assessment of RNAi‐based GM plants

  2017cites this paper
• Strategy for Generic Resistance Against Begomoviruses Through RNAi

  2017cites this paper
• Transposable Element Bm1645 is a Source of BmAGO2-associated Small RNAs that affect its expression in Bombyx mori

  2017cites this paper
• The genome of Trichoplusia ni, an agricultural pest and novel model for small RNA biology

  2017influential citation
• Genetic Drift, Not Life History or RNAi, Determine Long-Term Evolution of Transposable Elements

  2016cites this paper
• Learning Genetic Transposition with an Interactive Computer Program

  2016cites this paper
• Drosophila cells use nanotube-like structures to transfer dsRNA and RNAi machinery between cells

  2016cites this paper
• Limitations of RNA interference as a potential technique for crop protection against insect pests

  2016cites this paper
• Functions of small RNAs in mosquitoes

  2016cites this paper
• Non-coding RNAs and Inter-kingdom Communication

  2016cites this paper
• Phylogenetic Origin and Diversification of RNAi Pathway Genes in Insects

  2016cites this paper
• Duplication and Diversification of Dipteran Argonaute Genes, and the Evolutionary Divergence of Piwi and Aubergine

  2016cites this paper
• RISC assembly: Coordination between small RNAs and Argonaute proteins.

  2016cites this paper
• Transposable element misregulation in Drosophila buzzatii–Drosophila koepferae interspecific hybrids

  2016cites this paper
• OcculterCut: A Comprehensive Survey of AT-Rich Regions in Fungal Genomes

  2016cites this paper
• Repeated Duplication of Argonaute2 Is Associated with Strong Selection and Testis Specialization in Drosophila

  2016influential citation
• Different Types of Small RNAs in Protozoa

  2016cites this paper
• De l'œuf à l'adulte : étude moléculaire et fonctionnelle de la répression des éléments transposables par les piARN au cours du développement chez drosophila melanogaster

  2016cites this paper
• Bioinformatic analyses of sense and antisense expression from terminal inverted repeat transposons in Drosophila somatic cells

  2016cites this paper
• Developmental inhibition of miR-iab8-3p disrupts mushroom body neuron structure and adult learning ability

  2016cites this paper
• Live imaging reveals maternally-guided, H3K9me-independent emergence of functional heterochromatin in Drosophila embryos

  2016influential citation
• A correlation between Long noncoding RNA and unpaired DNA silencing in Drosophila

  2016cites this paper