UDP induces intestinal epithelial migration via the P2Y6 receptor

No abstract is available for this paper.

• Publication year

  2013

• Venue

  British Journal of Pharmacology

• Publication date

  2013-10-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/bph.12334PMID 23941325PMCID PMC3799601
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  1996cited by this paper
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  1992cited by this paper
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  1990cited by this paper
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  1989cited by this paper
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  1989cited by this paper

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