Novel GES/IBC extended-spectrum beta-lactamase variants with carbapenemase activity in clinical enterobacteria.

No abstract is available for this paper.

• Publication year

  2004

• Venue

  FEMS Microbiology Letters

• Publication date

  2004-05-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1111/J.1574-6968.2004.TB09535.XPMID 15135524
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Characterization of In111, a class 1 integron that carries the extended-spectrum beta-lactamase gene blaIBC-1.

  2003cited by this paper
• Extended-spectrum beta-lactamase types in Klebsiella pneumoniae and Escherichia coli in two Greek hospitals.

  2003cited by this paper
• Outbreak of Infections Caused by Enterobacter cloacae Producing the Integron-Associated β-Lactamase IBC-1 in a Neonatal Intensive Care Unit of a Greek Hospital

  2002cited by this paper
• bla VIM-2 Cassette-Containing Novel Integrons in Metallo-β-Lactamase-Producing Pseudomonas aeruginosa and Pseudomonas putida Isolates Disseminated in a Korean Hospital

  2002cited by this paper
• Extended-Spectrum β-Lactamases in the 21st Century: Characterization, Epidemiology, and Detection of This Important Resistance Threat

  2001cited by this paper
• Molecular Cloning: A Laboratory Manual

  2001cited by this paper
• Novel Carbapenem-Hydrolyzing β-Lactamase, KPC-1, from a Carbapenem-Resistant Strain of Klebsiella pneumoniae

  2001cited by this paper
• GES-2, a Class A β-Lactamase fromPseudomonas aeruginosa with Increased Hydrolysis of Imipenem

  2001cited by this paper
• Biochemical Sequence Analyses of GES-1, a Novel Class A Extended-Spectrum β-Lactamase, and the Class 1 Integron In52 from Klebsiella pneumoniae

  2000cited by this paper
• IBC-1, a Novel Integron-Associated Class A β-Lactamase with Extended-Spectrum Properties Produced by anEnterobacter cloacae Clinical Strain

  2000cited by this paper
• Catalytic properties of class A β-lactamases : efficiency and diversity

  1998cited by this paper
• Catalytic properties of class A beta-lactamases: efficiency and diversity.

  1998cited by this paper
• Characterisation of integrons and antibiotic resistance genes in Danish multiresistant Salmonella enterica Typhimurium DT104.

  1998cited by this paper
• Characterization of the 6'-N-aminoglycoside acetyltransferase gene aac(6')-Im [corrected] associated with a sulI-type integron

  1997cited by this paper
• Extended-spectrum and inhibitor-resistant TEM-type beta-lactamases: mutations, specificity, and three-dimensional structure

  1995cited by this paper
• PCR mapping of integrons reveals several novel combinations of resistance genes

  1995cited by this paper
• Biochemical properties of a carbapenem-hydrolyzing beta-lactamase from Enterobacter cloacae and cloning of the gene into Escherichia coli

  1993cited by this paper
• Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically

  1990cited by this paper
• National Committee for Clinical Laboratory Standards.

  1980cited by this paper

• Antibiotic resistance genes in Escherichia coli – literature review

  2025cites this paper
• «An accurate amplification-free CRISPR/Cas12a-based assay for GES β-lactamase detection».

  2025cites this paper
• Global genomic epidemiology of blaGES-5 carbapenemase-associated integrons

  2024cites this paper
• What do We Know so Far about Ges Carbapenemases, and What Threat do They Pose?

  2024cites this paper
• Are GES carbapenemases underdiagnosed? An allelic discrimination assay for their accurate detection and differentiation.

  2023cites this paper
• Phylogenetic predictions of carbapenemase activity from the Guiana extended-spectrum (GES) family of β-lactamases

  2023cites this paper
• Whole-Genome Sequencing-Based Resistome Analysis of Nosocomial Multidrug-Resistant Non-Fermenting Gram-Negative Pathogens from the Balkans

  2023cites this paper
• Characterization of Beta-Lactam Resistome of Escherichia coli Causing Nosocomial Infections

  2023cites this paper
• Analysis of Extended Spectrum Beta Lactamase (ESBL) Genes of Non-Invasive ESBL Enterobacterales in Southeast Austria in 2017

  2022cites this paper
• Genomic characterization of three GES-producing Enterobacterales isolated in the Czech Republic.

  2022cites this paper
• Metallo-β-lactamases in the Age of Multidrug Resistance: From Structure and Mechanism to Evolution, Dissemination, and Inhibitor Design.

  2021cites this paper
• Genetic Diversity, Biochemical Properties, and Detection Methods of Minor Carbapenemases in Enterobacterales

  2021influential citation
• Carbapenem-resistant bacteria over a wastewater treatment process: Carbapenem-resistant Enterobacteriaceae in untreated wastewater and intrinsically-resistant bacteria in final effluent

  2021cites this paper
• Clinical Laboratory Aspect of Carbapenem-Resistant Enterobacteriaceae

  2020cites this paper
• First Detection of GES-5-Producing Escherichia coli from Livestock—An Increasing Diversity of Carbapenemases Recognized from German Pig Production

  2020cites this paper
• Extended-spectrum beta-lactamase (ESBL)-producing Eschericia coli from livestock

  2020cites this paper
• Plasmid evolution in carbapenemase‐producing Enterobacteriaceae: a review

  2019cites this paper
• ESBLs and resistance to ceftazidime/avibactam and ceftolozane/tazobactam combinations in Escherichia coli and Pseudomonas aeruginosa.

  2019cites this paper
• Molecular detection of antibiotic resistance genes, and class I, and II integrons in Salmonella enteritidis isolated from Iranian one-day-old chicks

  2019cites this paper
• Characterisation of a class 1 integron associated with the formation of quadruple blaGES-5 cassettes from an IncP-1β group plasmid in Pseudomonas aeruginosa.

  2018cites this paper
• Emergence of sequence type 252 Enterobacter cloacae producing GES-5 carbapenemase in a Czech hospital.

  2018cites this paper
• Carbapenemase-producing Enterobacteriaceae in South Korea: a report from the National Laboratory Surveillance System.

  2018cites this paper
• Unravelling the genome of a Pseudomonas aeruginosa isolate belonging to the high-risk clone ST235 reveals an integrative conjugative element housing a blaGES-6 carbapenemase

  2018cites this paper
• Functional metagenomics reveals a novel carbapenem-hydrolyzing mobile beta-lactamase from Indian river sediments contaminated with antibiotic production waste.

  2018cites this paper
• Spread of GES-5 carbapenemase-producing Pseudomonas aeruginosa clinical isolates in Japan due to clonal expansion of ST235

  2018cites this paper
• Acquisition of Extended-Spectrum β-Lactamase GES-6 Leading to Resistance to Ceftolozane-Tazobactam Combination in Pseudomonas aeruginosa

  2018cites this paper
• Characterization of a novel class A carbapenemase PAD-1 from Paramesorhizobium desertii A-3-ET, a strain highly resistant to β-lactam antibiotics

  2017cites this paper
• Whole genome sequencing of ESBL-producing Escherichia coli isolated from patients, farm waste and canals in Thailand

  2017cites this paper
• Multicentre evaluation of the BYG Carba v2.0 test, a simplified electrochemical assay for the rapid laboratory detection of carbapenemase-producing Enterobacteriaceae

  2017cites this paper
• ESBL-producing Escherichia coli 
and Its Rapid Rise among Healthy People.

  2017cites this paper
• Epidemiology of NDM-1 and its Variants in Multidrug Resistant Gram-Negative Bacilli Isolated from Infection in Cancer Patients

  2017cites this paper
• RETRACTED ARTICLE: Prevalence and emergence of carbapenemases-producing Gram-negative bacteria in Mediterranean basin

  2017cites this paper
• In silico serine β-lactamases analysis reveals a huge potential resistome in environmental and pathogenic species

  2017cites this paper
• The epidemiology of carbapenemases in Latin America and the Caribbean

  2017cites this paper
• Global Dissemination of Carbapenemase-Producing Klebsiella pneumoniae: Epidemiology, Genetic Context, Treatment Options, and Detection Methods

  2016cites this paper
• Decoding the Structural Basis For Carbapenem Hydrolysis By Class A β-lactamases: Fishing For A Pharmacophore.

  2016cites this paper
• Structural and Functional Aspects of Class A Carbapenemases

  2016cites this paper
• Antibiotic resistance profiles of Pseudomonas aeruginosa isolated from various Greek aquatic environments.

  2016cites this paper
• Antimicrobial Resistance of ESBL Producing Coliforms Isolated fromRetail Meat Samples

  2016cites this paper
• Isolation of Carbapenemase Producing Enterobacteriaceae in the Greater Toronto Area's Sewage Treatment Plants and Surface Waters, and their Comparison to Clinical CPE from Toronto

  2016cites this paper
• Characterization of pKP-M1144, a Novel ColE1-Like Plasmid Encoding IMP-8, GES-5, and BEL-1 β-Lactamases, from a Klebsiella pneumoniae Sequence Type 252 Isolate

  2015influential citation
• Molecular characterization and phenotypic analysis of multidrug-resistant Escherichia coli and Klebsiella pneumoniae isolates from a tertiary-care hospital in Yunnan Province, China

  2015cites this paper
• Superintendence of antimicrobial resistance observed in bacterial flora isolated from human faecal carriage in Vellore, India

  2015cites this paper
• Characterization of a new genetic environment associated with GES-6 carbapenemase from a Pseudomonas aeruginosa isolate belonging to the high-risk clone ST235.

  2015cites this paper
• Evaluation of the BYG Carba Test, a New Electrochemical Assay for Rapid Laboratory Detection of Carbapenemase-Producing Enterobacteriaceae

  2015cites this paper
• Genetic Characterization of Carbapenem-Resistant Enterobacteriaceae and the Spread of Carbapenem-Resistant Klebsiella pneumonia ST340 at a University Hospital in Thailand

  2015cites this paper
• Kinetic and Structural Requirements for Carbapenemase Activity in GES-Type β-Lactamases

  2014cites this paper
• A report on the presence of GES-5 extended spectrum beta-lactamase producing Pseudomonas aeruginosa associated with urinary tract infection from north-east India

  2014cites this paper
• How to detect carbapenemase producers? A literature review of phenotypic and molecular methods.

  2014cites this paper
• Prevalence and molecular epidemiology of extended-spectrum beta-lactamase-producing and carbapenem-resistant enterobacteriaceae, acinetobacter baumannii and pseudomonas aeruginosa in Port Elizabeth

  2014cites this paper
• "Stormy waters ahead": global emergence of

  2013cites this paper
• “Stormy waters ahead”: global emergence of carbapenemases

  2013cites this paper
• β-lactamase-mediated resistance: a biochemical, epidemiological and genetic overview.

  2012cites this paper
• Kinetic and Crystallographic Studies of Extended-Spectrum GES-11, GES-12, and GES-14 β-Lactamases

  2012cites this paper
• Carbapenem resistance in Enterobacteriaceae: here is the storm!

  2012cites this paper
• GES-18, a New Carbapenem-Hydrolyzing GES-Type β-Lactamase from Pseudomonas aeruginosa That Contains Ile80 and Ser170 Residues

  2012cites this paper
• Ser 170 Residues Pseudomonas aeruginosa That Contains-Lactamase from β GES-Type GES-18 , a New Carbapenem-Hydrolyzing

  2012cites this paper
• The basis for carbapenem hydrolysis by class A β-lactamases: a combined investigation using crystallography and simulations.

  2012cites this paper
• Identification of Products of Inhibition of GES-2 β-Lactamase by Tazobactam by X-ray Crystallography and Spectrometry*

  2011cites this paper
• Investigating the Regulatory Mechanisms of Antibiotic Resistance in Gram-negative Pathogens

  2011cites this paper
• Emergence of Escherichia coli Sequence Type ST131 Carrying both the blaGES-5 and blaCTX-M-15 Genes

  2011cites this paper
• Importance of Position 170 in the Inhibition of GES-Type β-Lactamases by Clavulanic Acid

  2011cites this paper
• Carbapenem-Hydrolyzing GES-5-Encoding Gene on Different Plasmid Types Recovered from a Bacterial Community in a Sewage Treatment Plant

  2011cites this paper
• Comparative Biochemical and Computational Study of the Role of Naturally Occurring Mutations at Ambler Positions 104 and 170 in GES β-Lactamases

  2010cites this paper
• GES-13, a (cid:1) -Lactamase Variant Possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa (cid:1)

  2010cites this paper
• Programa de pós-graduação em Microbiologia

  2010cites this paper
• GES Extended-Spectrum β-Lactamases in Acinetobacter baumannii Isolates in Belgium

  2010influential citation
• GES-13, a β-Lactamase Variant Possessing Lys-104 and Asn-170 in Pseudomonas aeruginosa

  2010cites this paper
• Mechanistic Basis for the Emergence of Catalytic Competence against Carbapenem Antibiotics by the GES Family of β-Lactamases

  2009cites this paper
• GES-11, a Novel Integron-Associated GES Variant in Acinetobacter baumannii

  2009cites this paper
• Nosocomial Spread of Colistin-Only-Sensitive Sequence Type 235 Pseudomonas aeruginosa Isolates Producing the Extended-Spectrum β-Lactamases GES-1 and GES-5 in Spain

  2009influential citation
• Pseudomonas aeruginosa producing the extended-spectrum β-

  2009cites this paper
• Detection of 140 clinically relevant antibiotic-resistance genes in the plasmid metagenome of wastewater treatment plant bacteria showing reduced susceptibility to selected antibiotics.

  2009cites this paper
• Diversity of β-Lactamases Produced by Ceftazidime-Resistant Pseudomonas aeruginosa Isolates Causing Bloodstream Infections in Brazil

  2009cites this paper
• Spread of OXA-48-Positive Carbapenem-Resistant Klebsiella pneumoniae Isolates in Istanbul, Turkey

  2008cites this paper
• Emergence of class 1 integron-associated GES-5 and GES-5-like extended-spectrum beta-lactamases in clinical isolates of Pseudomonas aeruginosa in South Africa.

  2008cites this paper
• Evolution of extended-spectrum beta-lactamases by mutation.

  2008cites this paper
• Molecular Characterization and Epidemiology of Extended-Spectrum- β-Lactamase-Producing Escherichia coli and Klebsiella pneumoniae Isolates Causing Health Care-Associated Infection in Thailand, Where the CTX-M Family Is Endemic

  2008cites this paper
• Résistance bactérienne : définitions, mécanismes, évolution

  2008cites this paper
• Rapid detection of GES-type extended-spectrum β-lactamases in Pseudomonas aeruginosa with a peptide nucleic acid-based realtime PCR assay

  2008cites this paper
• Defining an extended‐spectrum β‐lactamase

  2008cites this paper
• Evolution of extended-spectrum β-lactamases by mutation

  2008cites this paper
• Entérobactéries des bêtalactamines

  2008cites this paper
• Defining an extended-spectrum beta-lactamase.

  2008cites this paper
• Chaitat Endemic Thailand , Where the CTX-M Family Is Health Care-Associated Infection in Isolates Causing Klebsiella pneumoniae and Escherichia coli-Lactamase-Producing β Epidemiology of Extended-Spectrum-Molecular Characterization and

  2008cites this paper
• Insight into the plasmid metagenome of wastewater treatment plant bacteria showing reduced susceptibility to antimicrobial drugs analysed by the 454-pyrosequencing technology.

  2008cites this paper
• Stability of GES-type extended-spectrum ß-lactamase genes during antibiotic exposure

  2007cites this paper
• Carbapenem Resistance in Klebsiella pneumoniae and Other Members of the Family Enterobacteriaceae

  2007cites this paper
• Genetic and biochemical characterization of GES-5, an extended-spectrum class A beta-lactamase from Klebsiella pneumoniae.

  2007cites this paper
• Structure of GES-1 at atomic resolution: insights into the evolution of carbapenamase activity in the class A extended-spectrum beta-lactamases.

  2007influential citation
• Class A carbapenemases.

  2007cites this paper
• Porin loss and GES-type extended-spectrum beta-lactamase primarily responsible for reduced susceptibility to imipenem.

  2007cites this paper
• Carbapenemases: molecular diversity and clinical consequences.

  2007cites this paper
• Emergence of blaGES-5 in clinical colistin-only-sensitive (COS) Pseudomonas aeruginosa strain in Brazil.

  2007cites this paper
• Virulence factors and drug resistance in Escherichia coli isolated from extraintestinal infections.

  2007cites this paper
• Carbapenemases: the Versatile (cid:2) -Lactamases

  2007influential citation
• Carbapenemases: the Versatile (cid:2) -Lactamases

  2007influential citation
• Carbapenemases: the versatile beta-lactamases.

  2007cites this paper
• Four exact GES variants used for identification of GES-type extended-spectrum β-lactamases with different hydrolysis profiles and inhibitor-resistance patterns by pyrosequencing

  2007cites this paper
• Risk factors of carbapenem-resistant Klebsiella pneumoniae infections: a matched case control study.

  2007cites this paper