Drosophila ATM and ATR have distinct activities in the regulation of meiotic DNA damage and repair

E. Joyce,Michael Pedersen,Stanley Tiong,Sanese K. White-Brown,Anshu Paul,S. Campbell,K. McKim

Published 2011 in Journal of Cell Biology

ABSTRACT

ATM and ATR display distinct activities in meiotic DSB repair, such that ATM functions in DNA damage repair and negative feedback control over programmed double strand breaks, whereas ATR is required for checkpoint activity.

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