Phenotypical and Functional Characterization of Clinical Grade Dendritic Cells

No abstract is available for this paper.

• Publication year

  2002

• Venue

  Journal of immunotherapy

• Publication date

  2002-09-01

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1097/00002371-200209000-00007PMID 12218781
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

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  2001influential reference
• The role of chemokine receptors in primary, effector, and memory immune responses.

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  1999influential reference
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  1999cited by this paper
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  1999cited by this paper
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  1999influential reference
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  1998cited by this paper
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  1998cited by this paper
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• Generation of mature dendritic cells from human blood. An improved method with special regard to clinical applicability.

  1996cited by this paper
• Human blood dendritic cells selectively express CD83, a member of the immunoglobulin superfamily.

  1995influential reference
• Melanocyte lineage-specific antigen gp100 is recognized by melanoma- derived tumor-infiltrating lymphocytes

  1994cited by this paper
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