Production of Free Light Chains of Immunoglobulin by a Hematopoietic Cell Line Derived from a Patient with Multiple Myeloma.∗

No abstract is available for this paper.

• Publication year

  1967

• Venue

  Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine

• Publication date

  1967-08-01

• Fields of study

  Medicine, Chemistry

• Identifiers
  DOI 10.3181/00379727-125-32327PMID 6042436
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Culture of normal human leukocytes.

  1967cited by this paper
• Leukocyte cultures of patients with leukemia and lymphomas.

  1966cited by this paper
• Continuous cell culture from a patient with chronic myelogenous leukemia. I. Propagation and presence of Philadelphia chromosome.

  1966cited by this paper
• Immunoglobulin Synthesis in vitro by Established Human Cell Lines

  1966cited by this paper
• Immunoglobulin production in human leukemia cell lines.

  1966cited by this paper
• Serial Cultivation of Human Leukemic Cells.∗

  1966cited by this paper
• BURKITT TUMOR: TISSUE CULTURE, CYTOGENETIC AND VIRUS STUDIES.

  1965cited by this paper
• CHARACTERISTICS AND MODE OF GROWTH OF TISSUE CULTURE STRAIN (EB1) OF HUMAN LYMPHOBLASTS FROM BURKITT'S LYMPHOMA.

  1965cited by this paper
• Continuous culture of human lymphoblasts from peripheral blood of a child with acute leukemia

  1965cited by this paper
• STUDIES OF THIRTY DIFFERENT BENCE JONES PROTEIN-PRODUCING PLASMA CELL NEOPLASMS IN AN INBRED STRAIN OF MOUSE.

  1964cited by this paper
• CYTOLOGY OF BURKITT'S TUMOUR (AFRICAN LYMPHOMA).

  1964cited by this paper
• QUANTITATIVE DETERMINATION OF 6.6 S GAMMA-GLOBULINS, BETA-2A-GLOBULINS AND GAMMA-1-MACROGLOBULINS IN HUMAN SERUM.

  1963cited by this paper
• Reduction of gamma-globulins.

  1962cited by this paper

• Corticosteroids ameliorate CAR T-cell-induced cytokine-release syndrome without inhibiting multiple myeloma treatment

  2026cites this paper
• PCNEO, a New Proficiency Testing Program for Flow Cytometric Analysis of Plasma Cell Neoplasms From the College of American Pathologists Diagnostic Immunology and Flow Cytometry Committee.

  2023cites this paper
• Cytotoxic T Cells Activated by Self-differentiated Monocyte-derived Dendritic Cells Against Multiple Myeloma Cells

  2022cites this paper
• Preparation of the Murine Anti-Human P2X7 Receptor Monoclonal Antibody (Clone L4).

  2022cites this paper
• Efficacy and safety of artemether-lumefantrine and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria and prevalence of molecular markers associated with artemisinin and partner drug resistance in Uganda

  2021cites this paper
• Remodelling of Ca2+ homeostasis is linked to enlarged endoplasmic reticulum in secretory cells.

  2021cites this paper
• Targeting phosphoglycerate dehydrogenase in multiple myeloma

  2020cites this paper
• B-cell maturation antigen expression across hematologic cancers: a systematic literature review

  2020cites this paper
• CDKN1A Gene Expression in Two Multiple Myeloma Cell Lines With Different P53 Functionality

  2020cites this paper
• Highly efficient CRISPR-Cas9-mediated gene knockout in primary human B cells for functional genetic studies of Epstein-Barr virus infection

  2020cites this paper
• Evaluating the efficacy of multiple myeloma cell lines as models for patient tumors via transcriptomic correlation analysis

  2019cites this paper
• Interferon γ is a strong, STAT1-dependent direct inducer of BCL6 expression in multiple myeloma cells.

  2018cites this paper
• Combined treatment of human multiple myeloma cells with bortezomib and doxorubicin alters the interactome of 20S proteasomes

  2018cites this paper
• University of Groningen Clinical and biological aspects of Multiple Myeloma

  2017cites this paper
• Oridonin Induces Apoptosis of Myeloma Cells by Inducing C-Myc Degradation via Nuclear Accumulation of Fbxw 7

  2017cites this paper
• Developing novel agents targeting the NF-κB pathway for the treatment of multiple myeloma

  2017cites this paper
• Glycosylation and oligomeric state of envelope protein might influence HIV-1 virion capture by α4β7 integrin.

  2017cites this paper
• YM155 suppresses proliferation and survival of multiple myeloma cells via proteasomal degradation of c-Myc.

  2016cites this paper
• Gene integrated set profile analysis: a context-based approach for inferring biological endpoints

  2016cites this paper
• Targeted knockdown of DJ-1 induces multiple myeloma cell death via KLF6 upregulation

  2016cites this paper
• Proton pump inhibitors induce a caspase-independent antitumor effect against human multiple myeloma.

  2016cites this paper
• TrxR1 inhibition overcomes both hypoxia-induced and acquired bortezomib resistance in multiple myeloma through NF-кβ inhibition

  2016cites this paper
• Potential Small Guide RNAs for tRNase ZL from Human Plasma, Peripheral Blood Mononuclear Cells, and Cultured Cell Lines

  2015influential citation
• Use of Human Hybridoma Technology To Isolate Human Monoclonal Antibodies

  2015cites this paper
• Cross-talk between two antioxidants, thioredoxin reductase and heme oxygenase-1, and therapeutic implications for multiple myeloma

  2015cites this paper
• Inflammatory environment created by fibroblast aggregates induces growth arrest and phenotypic shift of human myeloma cells.

  2015cites this paper
• Lactate, a putative survival factor for myeloma cells, is incorporated by myeloma cells through monocarboxylate transporters 1

  2015cites this paper
• Shikonin, dually functions as a proteasome inhibitor and a necroptosis inducer in multiple myeloma cells

  2014influential citation
• Secrets to finding the ideal mate:New insights into parameters that govern successful Adeno-associated virus (AAV) vector evolution

  2014cites this paper
• Screening of a heptamer-type sgRNA library for potential therapeutic agents against hematological malignancies.

  2014cites this paper
• G2/M-phase accumulation and apoptosis in multiple myeloma cells IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces

  2013cites this paper
• dexamethasone Rapamycin sensitizes multiple myeloma cells to apoptosis induced by

  2013cites this paper
• Hypoxia reduces CD138 expression and induces an immature and stem cell-like transcriptional program in myeloma cells

  2013cites this paper
• Cell Lines and Human Primary Cells

  2013cites this paper
• Use of in vitro primary culture models to investigate the activity of standard and novel therapies in haematological malignancies

  2013cites this paper
• leading to suppression of proliferation and induction of apoptosis kinase in human multiple myeloma cells α B κ B and I κ nuclear factor Curcumin (Diferuloylmethane) downregulates the constitutive activation of

  2013cites this paper
• Proteasome inhibition in the regulation of natural killer cell function and multiple myeloma cell apoptosis

  2013cites this paper
• Karyotypic variability of human multiple myeloma cell lines

  2012cites this paper
• Cancer Therapy Using Viral- and Bacterial Proteins, as Vectors for Vaccines or as Carriers of Cytostatics

  2012cites this paper
• The HDAC Inhibitor LBH589 Enhances the Antimyeloma Effects of the IGF-1RTK Inhibitor Picropodophyllin

  2012cites this paper
• PDK1 inhibition is a novel therapeutic target in multiple myeloma

  2012cites this paper
• Naltrindole Inhibits Human Multiple Myeloma Cell Proliferation In Vitro and in a Murine Xenograft Model In Vivo

  2012cites this paper
• The HDAC inhibitor LBH 589 enhances the anti-myeloma effects of the IGF-1 RTK inhibitor picropodophyllin

  2012cites this paper
• Bone Marrow‐Derived Mesenchymal Stromal Cells are Attracted by Multiple Myeloma Cell‐Produced Chemokine CCL25 and Favor Myeloma Cell Growth in Vitro and In Vivo

  2012cites this paper
• Elimination of Specific miRNAs by Naked 14-nt sgRNAs

  2012influential citation
• Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes.

  2012cites this paper
• Molecular and Cellular Biology of Multidrug Resistance in Tumor Cells

  2012cites this paper
• Over-accumulation of nuclear IGF-1 receptor in tumor cells requires elevated expression of the receptor and the SUMO-conjugating enzyme Ubc9.

  2011cites this paper
• Aus der Sektion für Stammzell- und Immuntherapie (Direktor: Prof. Dr. med. Martin Gramatzki) im Universitätsklinikum Schleswig-Holstein, Campus Kiel an der Christian-Albrechts-Universität zu Kiel HM1.24 GERICHTETE BISPEZIFISCHE SINGLE-CHAIN-FV ANTIKÖRPER ZUR THERAPIE DES MULTIPLEN MYELOMS

  2011cites this paper
• antibodies and magnetic immunobeads Elimination of myeloma cells from bone marrow by using monoclonal

  2011cites this paper
• Quantitative proteomic analysis of tumor reversion in multiple myeloma cells.

  2011cites this paper
• culture having a rearranged cellular myc proto-oncogene Establishment and characterization of a human plasma cell myeloma

  2011cites this paper
• Targeting MAGE-C1/CT7 Expression Increases Cell Sensitivity to the Proteasome Inhibitor Bortezomib in Multiple Myeloma Cell Lines

  2011cites this paper
• Genz-644282, a Novel Non-Camptothecin Topoisomerase I Inhibitor for Cancer Treatment

  2011cites this paper
• Toward Personalized Medicine: The potential role of RNA interference in Plasma Cell Dyscrasia

  2011cites this paper
• Ex Vivo Expansion of Human Hematopoietic Stem Cells by Garcinol, a Potent Inhibitor of Histone Acetyltransferase

  2011cites this paper
• lines by a plasma cell-reactive monoclonal antibody and complement Elimination of clonogenic stem cells from human multiple myeloma cell

  2011cites this paper
• TRAIL produced from multiple myeloma cells is associated with osteolytic markers.

  2011cites this paper
• The Human Lung Adenocarcinoma Cell Line EKVX Produces an Infectious Xenotropic Murine Leukemia Virus

  2011cites this paper
• early plasma-cell differentiation and c-myc activation The human myeloma cell line LP-1: a versatile model in which to study

  2011cites this paper
• Inhibition of pathologic immunoglobulin-free light chain production by small interfering RNA molecules.

  2010cites this paper
• Polycomb Target Genes Are Silenced in Multiple Myeloma

  2010cites this paper
• Bone marrow CFU-GM and human tumor xenograft efficacy of three tubulin binding agents

  2009cites this paper
• Dendritic cells-based T-cell immune response for the variable region of immunoglobulin light chain of myeloma and lymphoma cell lines.

  2009cites this paper
• Epstein-Barr virus infection leads to partial phenotypic reversion of terminally differentiated malignant B cells.

  2009cites this paper
• Crystal structure, antitumour and antimetastatic activities of disubstituted fused 1,2,4-triazinones.

  2009cites this paper
• Presence of alpha-naphthyl acetate esterase activity in human haematopoietic cell lines and in fresh biopsy specimens of lymphoma and myeloma.

  2009cites this paper
• Bone marrow CFU-GM and human tumor xenograft efficacy of three antitumor nucleoside analogs.

  2009cites this paper
• Converting cell lines representing hematological malignancies from glucocorticoid-resistant to glucocorticoid-sensitive: signaling pathway interactions.

  2009cites this paper
• Interferon therapy in multiple myeloma.

  2009cites this paper
• An integrated microfluidic chip for chromosome enumeration using fluorescence in situ hybridization.

  2008cites this paper
• Bone marrow and tumor cell colony-forming units and human tumor xenograft efficacy of noncamptothecin and camptothecin topoisomerase I inhibitors

  2008cites this paper
• Serum Free Light Chain Analysis, 4th Edition

  2008cites this paper
• Epigenetic silencing of the interferon regulatory factor ICSBP/IRF8 in human multiple myeloma.

  2008cites this paper
• Growth control of multiple myeloma cells through inhibition of glycogen synthase kinase-3

  2008cites this paper
• Serological distinction between DR antigens and lymphocyte activating determinants.

  2008cites this paper
• Synthesis, determination of the lipophilicity, anticancer and antimicrobial properties of some fused 1,2,4-triazole derivatives.

  2008cites this paper
• Gammadelta T cells recognize tumor cells via CDR3delta region.

  2007cites this paper
• Clinical and biological aspects of Multiple Myeloma

  2007cites this paper
• Stereoselective synthesis of bis-steroidal pyrazine derivatives

  2007cites this paper
• γδ T cells recognize tumor cells via CDR3δ region

  2007cites this paper
• Influence of imidazoline aryl derivatives containing the methylthioether group on the viability of RPMI 8226 and HeLa cancer cells

  2007cites this paper
• Identification of antitumour activity of novel derivatives of 8-aryl-2,6,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazine-3,4-dione and 8-aryl-4-imino-2,3,7,8-tetrahydroimidazo[2,1-c][1,2,4]triazin-3(6H)-one.

  2007cites this paper
• Activation of the endoplasmic reticulum stress pathway is associated with survival of myeloma cells

  2006cites this paper
• Synopsis of a Roundtable on Validating Novel Therapeutics for Multiple Myeloma

  2006cites this paper
• ESTABLISHMENT AND CHARACTERIZATION OF A HUMAN HYBRIDIZATION WITH HUMAN B CELLS NON-SECRETORY PLASMACYTOID CELL LINE AND ITS

  2006cites this paper
• Thymidine secretion by hybridoma and myeloma cells.

  2006cites this paper
• Activated γδ T cells express the natural cytotoxicity receptor natural killer p44 and show cytotoxic activity against myeloma cells

  2006cites this paper
• IGF-1 receptor tyrosine kinase inhibition by the cyclolignan PPP induces G2/M-phase accumulation and apoptosis in multiple myeloma cells.

  2006cites this paper
• Expression of mRNA for a newly identified Pax5 exon is reduced in multiple myeloma

  2006cites this paper
• Activated gammadelta T cells express the natural cytotoxicity receptor natural killer p 44 and show cytotoxic activity against myeloma cells.

  2006cites this paper
• Messenger RNA of Growth Inhibition with Induction of Glucocorticoid Receptor Glucocorticoid Effects on Myeloma Cells in Culture : Correlation Updated

  2006cites this paper
• Direct and Indirect Effects of Human Recombinant 7-lnterferon on Tumor Cells in a Clonogenic Assay1

  2006cites this paper
• Establishment and Phenotypic Characterization of Three New Human Myeloma Cell Lines ( U-1957 , U-1958 , and U-i 996 ) By

  2005cites this paper
• myeloma cell lines ( U-1957 , U-1958 , and U-1996 ) Establishment and phenotypic characterization of three new human

  2005cites this paper
• Coculture with dendritic cells promotes proliferation but not cytotoxic activity of gamma/delta T cells.

  2005cites this paper
• Notch signaling is a potent inducer of growth arrest and apoptosis in a wide range of B-cell malignancies.

  2005cites this paper
• Cytotoxic effects of glutathione synthesis inhibition by L-buthionine-(SR)-sulfoximine on human and murine tumor cells

  2004cites this paper
• Development and characterization of two human tumor sublines expressing high-grade resistance to the cyanoguanidine CHS 828

  2004cites this paper
• Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1330

  2004cites this paper