Use of ramipril in preventing stroke: double blind randomised trial

No abstract is available for this paper.

• Publication year

  2002

• Venue

  British medical journal

• Publication date

  2002-03-23

• Fields of study

  Medicine

• Identifiers
  DOI 10.1136/bmj.324.7339.699PMID 11909785PMCID PMC99052
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack.

  2001cited by this paper
• Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association.

  2001cited by this paper
• Primary prevention of ischemic stroke: A statement for healthcare professionals from the Stroke Council of the American Heart Association.

  2001cited by this paper
• Clinical trials report

  2001cited by this paper
• Effects of Ramipril and Vitamin E on Atherosclerosis: The Study to Evaluate Carotid Ultrasound Changes in Patients Treated With Ramipril and Vitamin E (SECURE)

  2001cited by this paper
• Vitamin E supplementation and cardiovascular events in high-risk patients.

  2000cited by this paper
• Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients.

  2000cited by this paper
• Prevalence of stroke : a door-to-door survey in rural Bolivia.

  2000cited by this paper
• Association of systolic blood pressure with macrovascular and microvascular complications of type 2 diabetes (UKPDS 36): prospective observational study

  2000cited by this paper
• American Heart Association Prevention Conference IV: Prevention and Rehabilitation of Stroke Introduction

  1997cited by this paper
• Alternative projections of mortality and disability by cause 1990-2020: Global Burden of Disease Study.

  1997cited by this paper
• American Heart Association Prevention Conference IV: prevention and rehabilitation of stroke: executive summary.

  1997cited by this paper
• The Global Burden of Disease

  1996cited by this paper
• The HOPE (Heart Outcomes Prevention Evaluation) Study: the design of a large, simple randomized trial of an angiotensin-converting enzyme inhibitor (ramipril) and vitamin E in patients at high risk of cardiovascular events. The HOPE study investigators.

  1996cited by this paper
• PROGRESS (perindopril protection against recurrent stroke study): rationale and design. PROGRESS Management Committee [corrected].

  1995cited by this paper
• The PROGRESS study: Rationale and design

  1995cited by this paper
• Collaborative overview of randomised trials of antiplatelet therapy--I: Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients. Antiplatelet Trialists' Collaboration.

  1994cited by this paper
• Emerging role of angiotensin-converting enzyme inhibitors in cardiac and vascular protection.

  1994cited by this paper
• Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients

  1994cited by this paper
• Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context.

  1990cited by this paper
• Letters to the EditorSALT AND HYPERTENSION

  1980cited by this paper
• Salt and hypertension.

  1979cited by this paper
• Nonparametric Estimation from Incomplete Observations

  1958cited by this paper

• Unveiling novel bladder cancer associations from multicentred primary and secondary care electronic health records by machine learning: a case-control study

  2025cites this paper
• Multidomain interventions for preventing cognitive decline in older adults with type 2 diabetes and mild cognitive impairment: Secondary analysis of the J-MINT

  2025cites this paper
• Morphologic variation of the circle of Willis is associated with cognitive impairment in a general population: the J-SHIPP study.

  2025cites this paper
• Comprehensive investigation of Prunus armeniaca for natural green synthesis of carbon quantum dots; Applications as fluorescent nano-probes for ramipril.

  2025cites this paper
• Chronic Treatment of a Mouse Model of Cerebral Amyloid Angiopathy and Brain AT1 Receptor Expression

  2025cites this paper
• Safety and efficacy of anticoagulant administration in people with atrial fibrillation and advanced chronic kidney disease

  2025cites this paper
• ACE Inhibitors and Angiotensin Receptor Blockers for the Primary and Secondary Prevention of Cardiovascular Outcomes: Recommendations from the 2024 Egyptian Cardiology Expert Consensus in Collaboration with the CVREP Foundation

  2024cites this paper
• Randomized Trial of a Social Support Intervention to Improve Home Blood Pressure Monitoring in Patients With Cerebrovascular Disease

  2023cites this paper
• In Reply: ACEI and ARB - Each Unique RAAS Inhibitors: The Importance of Impact on Inflammation.

  2023cites this paper
• Association and progression of multi-morbidity with Chronic Kidney Disease stage 3a secondary to Type 2 Diabetes Mellitus, grouped by albuminuria status in the multi-ethnic population of Northwest London: A real-world study

  2023cites this paper
• Vitamin E supplementation (alone or with other antioxidants) and stroke: a meta-analysis.

  2023cites this paper
• Stroke risk management in carotid atherosclerotic disease: A Clinical Consensus Statement of the ESC Council on Stroke and the ESC Working Group on Aorta and Peripheral Vascular Diseases.

  2023cites this paper
• Timed-averaged blood pressure showed a J-curve association with stroke in elderly chronic kidney disease patients

  2022cites this paper
• Association study of polymorphism in Thrombomodulin gene (rs1042579) with cardiovascular disease

  2022cites this paper
• Long-Term Secondary Prevention: Management of Blood Pressure After a Transient Ischemic Attack or Stroke

  2022cites this paper
• Hypertension and cognitive dysfunction: a narrative review

  2022cites this paper
• Relationship Between Calcium Channel Blockers Therapy and Cognitive Function Improvement in Cognitive Decline Patients with Cerebrovascular Disease

  2022cites this paper
• Improving combination drug trials using 'definitive screening designs'.

  2022cites this paper
• Effect of Intensive Versus Standard Blood Pressure Control on Stroke Subtypes

  2021cites this paper
• Is Blood Pressure Lowering in the Very Elderly With Previous Stroke Associated With a Higher Risk of Adverse Events?

  2021cites this paper
• Chronic Use of Angiotensin Converting Enzyme Inhibitors and/or Angiotensin Receptor Blockers is Not Associated With Stroke After Noncardiac Surgery: A Retrospective Cohort Analysis

  2021cites this paper
• Chronic Renin-Angiotensin System Activation Induced Neuroinflammation: Common Mechanisms Underlying Hypertension and Dementia?

  2021cites this paper
• Targeting the Angiotensin II Type 1 Receptor in Cerebrovascular Diseases: Biased Signaling Raises New Hopes

  2021cites this paper
• Randomised trial on effect of involving media reporters in salt reduction programme to increase media reports and the public’s knowledge, belief and behaviors on salt and health: Changzhi reporters trial

  2021cites this paper
• Prescription audit of antihypertensive drugs used in stroke patients in a tertiary care teaching hospital

  2021cites this paper
• Complementary Medications (Statins, Nicergoline, Naftidrofuryl) in Dementia

  2021cites this paper
• Brain Renin–Angiotensin System at the Intersect of Physical and Cognitive Frailty

  2020cites this paper
• Hypothetical blood-pressure-lowering interventions and risk of stroke and dementia

  2020cites this paper
• The Possibilities of Single-Pill Combinations of Antihypertensive Drugs in Cerebroprotection: Focus on the Combination of Amlodipine with Ramipril

  2020cites this paper
• Should Angiotensin-Converting Enzyme Inhibitors ever Be Used for the Management of Hypertension?

  2020cites this paper
• The Renin-Angiotensin System and the Cerebrovascular Diseases: Experimental and Clinical Evidence.

  2019cites this paper
• Enfermedad vascular cerebral isquémica: revisión extensa de la bibliografía para el médico de primer contacto

  2019cites this paper
• EFFECTS OF ANTIHYPERTENSIVE TREATMENT ON COGNITIVE DECLINE

  2019cites this paper
• Geriatric Psychiatric and Cognitive Disorders: Depression, Dementia, and Delirium

  2019cites this paper
• Lower Extremity Peripheral Artery Disease: Diagnosis and Treatment.

  2019cites this paper
• Update on Hypertension Management 2019 , 20 , nr . 73 EFFECTS OF ANTIHYPERTENSIVE TREATMENT ON COGNITIVE DECLINE

  2019cites this paper
• Challenges of hypertension and dementia in the Indian subcontinent: a review

  2019cites this paper
• Mineralocorticoid Receptor Antagonism in Patients With Atrial Fibrillation: Findings From the ORBIT‐AF (Outcomes Registry for Better Informed Treatment of Atrial Fibrillation) Registry

  2018cites this paper
• Should Hypertension Be Treated in Late Life to Preserve Cognitive Function? Pro Side of the Argument.

  2018cites this paper
• Interference With Endothelial PPAR (Peroxisome Proliferator–Activated Receptor)-&ggr; Causes Accelerated Cerebral Vascular Dysfunction in Response to Endogenous Renin-Angiotensin System Activation

  2018cites this paper
• 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults. A report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

  2018cites this paper
• 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

  2018cites this paper
• Hypertension and Cognitive Function

  2018cites this paper
• The depressor axis of the renin-angiotensin system and brain disorders: a translational approach.

  2018cites this paper
• The impact of non-pharmacological treatment on symptom reduction and progression of mild cognitive impairment to dementia

  2018cites this paper
• Identifying strategies to inform interventions for the secondary prevention of stroke in UK primary care

  2018cites this paper
• Zerebrale Protektion durch Antihypertensiva

  2018cites this paper
• 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

  2018cites this paper
• ANTIHYPERTENSIVE EFFECTIVENESS OF A FIXED-DOSE COMBINATION OF RAMIPRIL/HYDROCHLOROTHIAZIDE IN THE GULF REGION: RESULTS FROM THE PACHA REGISTRY.

  2018cites this paper
• The D allele of the angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism is associated with worse functional outcome of ischaemic stroke

  2018cites this paper
• 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation, and Management of High Blood Pressure in Adults: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

  2018cites this paper
• EFFECT OF ANTIHYPERTENSIVE TREATMENT ON COGNITIVE FUNCTIONS ASSESSED BY EVENT RELATED POTENTIAL P300

  2018cites this paper
• Antihypertension drugs in prevention of cognition disorder and dementia: focus on calcium channel blockers and diuretics

  2018cites this paper
• Hypertension and cognitive impairment.

  2017cites this paper
• Defining the Relationship Between Hypertension, Cognitive Decline, and Dementia: a Review

  2017cites this paper
• Treatment options and considerations for hypertensive patients to prevent dementia

  2017cites this paper
• Risk Factor Management with Guideline-Based Medications for Prevention of Recurrent Ischemic Stroke: A Retrospective Chart Review

  2017cites this paper
• China Rural Health Initiative

  2017cites this paper
• Association between ace gene polymorphism and functional outcome of ischemic stroke

  2017cites this paper
• Antihypertensive Medication Use and Incident Alzheimer Disease

  2017cites this paper
• Optimizing care for patients with symptomatic carotid disease

  2017cites this paper
• Renin angiotensin system inhibitors for patients with stable coronary artery disease without heart failure: systematic review and meta-analysis of randomized trials

  2017cites this paper
• Treating Hypertension to Prevent Cognitive Decline and Dementia: Re-Opening the Debate.

  2017cites this paper
• Recurrent events and secondary prevention after acute cerebrovascular disease

  2017cites this paper
• Identification of Adverse Drug Reaction By Apriori Association Rule Learning

  2017cites this paper
• Hypertension and cognitive dysfunction in elderly: blood pressure management for this global burden

  2016cites this paper
• Hypertension Treatment in Blacks: Discussion of the U.S. Clinical Practice Guidelines.

  2016cites this paper
• Conditions That Can Promote Alzheimer’s

  2016cites this paper
• Use of Angiotensin-Converting Enzyme Inhibitors, Angiotensin Receptor Blockers, and Risk of Dementia in Heart Failure

  2016cites this paper
• Influence of Hypertension, Alone and in Combination with Other Vascular Risk Factors on Cognition.

  2016cites this paper
• Vascular dementia revised

  2016cites this paper
• Mild Cognitive Impairment

  2016cites this paper
• Renin-angiotensin system-targeting antihypertensive drugs and risk of vascular cognitive impairment: A meta-analysis.

  2016cites this paper
• In Reply-The Different Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers on Mortality.

  2016cites this paper
• Renin-angiotensin system as a potential therapeutic target in stroke and retinopathy: experimental and clinical evidence.

  2016cites this paper
• A Review of Antihypertensive Drugs and Choosing the Right Antihypertensive for Recurrent Stroke Prevention

  2016cites this paper
• Recurrent Ischemic Stroke Characteristics and Assessment of Sufficiency of Secondary Stroke Prevention.

  2015cites this paper
• Method Development, Validation and Pharmacokinetics for Ramipril and Hydrochlorothiazide in Human Plasma and Application in a Bioequivalence Study Based on Healthy Jordanian Volunteers

  2015cites this paper
• Association between eprosartan-based hypertension therapy and improvement in cognitive function score: long-term follow-up from the OSCAR observational study

  2015cites this paper
• The implications of angiotensin-converting enzymes and their modulators in neurodegenerative disorders: current and future perspectives.

  2015cites this paper
• Prevention of Poststroke Cognitive Decline: ASPIS – a Multicenter, Randomized, Observer-Blind, Parallel Group Clinical Trial to Evaluate Multiple Lifestyle Interventions – Study Design and Baseline Characteristics

  2015cites this paper
• Antihypertensive Drugs, Prevention of Cognitive Decline and Dementia: A Systematic Review of Observational Studies, Randomized Controlled Trials and Meta-Analyses, with Discussion of Potential Mechanisms

  2015influential citation
• Trends in the treatment of risk factors for stroke in a Czech stroke unit

  2015cites this paper
• Effects of blood pressure lowering treatment in acute stroke. Secondary analyses of the Scandinavian Candesartan Acute Stroke Trial

  2015cites this paper
• Benefit of initial dual-therapy on stroke prevention in Chinese hypertensive patients: a real world cohort study.

  2015cites this paper
• El cerebro y el daño neuropsiquiátrico de la hipertensión arterial

  2014cites this paper
• Epidemiology of CVD

  2014cites this paper
• Hypertension and Cardiovascular Disease and Its Management

  2014cites this paper
• Managing Cardiovascular Complications in Diabetes: Betteridge/Managing Cardiovascular Complications in Diabetes

  2014cites this paper
• [The effect of angiotensin receptor blockers in cerebrovascular disorders and dementia: bonus in addition to the antihypertensive effect].

  2014cites this paper
• Vascular Cognitive Disorder: A Diagnostic and Pharmacological Treatment Updating

  2014cites this paper
• Use of diuretics is associated with reduced risk of Alzheimer's disease: the Cache County Study.

  2014cites this paper
• NF-κB signaling at the crossroads of inflammation and atherogenesis: searching for new therapeutic links

  2014influential citation
• DYSARTHRIA POST STROKE ATTACK WITH UNCONTROLLED HYPERTENSION AND OBESITY ON A HOUSEWIFE

  2014cites this paper
• Lowering of Blood Pressure for Recurrent Stroke Prevention

  2014cites this paper
• INCREASING INDEPENDENT PRACTICE EARLY POST-STROKE TO ENHANCE UPPER EXTREMITY FUNCTION: A GLOBAL APPROACH

  2014cites this paper
• The diagnosis and management of mild cognitive impairment: a clinical review.

  2014cites this paper
• Drug Safety and Effectiveness Network Report: A Systematic Review with Network Meta-Analyses and Economic Evaluation Comparing Therapies for Hypertension in Non-Diabetic Patients

  2014cites this paper
• Factors Associated with Cognitive Decline in Transient Ischemic Attack Patients

  2014cites this paper
• Effect of hypertension on the structural and functional integrity of the young and aged brain in an inducible transgenic model

  2014cites this paper