Pathogenesis and treatment of hepatitis e virus infection.

No abstract is available for this paper.

• Publication year

  2012

• Venue

  Gastroenterology

• Publication date

  2012-05-01

• Fields of study

  Medicine

• Identifiers
  DOI 10.1053/j.gastro.2012.02.014PMID 22537448
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Molecular Virology of Hepatitis E Virus

  2013cited by this paper
• Global Burden of Hepatitis E Virus

  2012cited by this paper
• Chronic hepatitis E in hematopoietic stem cell transplant patients in a low‐endemic country?

  2012cited by this paper
• Widespread distribution of hepatitis E virus in plasma fractionation pools

  2012cited by this paper
• Liver transplant from a donor with occult HEV infection induced chronic hepatitis and cirrhosis in the recipient.

  2012cited by this paper
• Safety of the hepatitis E vaccine for pregnant women: A preliminary analysis

  2012cited by this paper
• Hepatitis E virus (HEV)‐specific T‐cell responses are associated with control of HEV infection

  2012cited by this paper
• HEV-specific T-cell responses are associated with control of HEV infection

  2012cited by this paper
• Hepatitis E Virus and the Kidney in Solid-Organ Transplant Patients

  2012cited by this paper
• Occurrence of hepatitis E virus RNA in plasma donations from Sweden, Germany and the United States

  2012cited by this paper
• Hepatitis E Virus Infection without Reactivation in Solid-Organ Transplant Recipients, France

  2011cited by this paper
• Analysis of acute to chronic hepatitis E: 6-10 year follow-up.

  2011cited by this paper
• Detection of hepatitis E virus (HEV) from porcine livers in Southeastern Germany and high sequence homology to human HEV isolates.

  2011cited by this paper
• 1254 RIBAVIRIN TREATMENT FOR CHRONIC HEPATITIS E: A CASE-SERIES

  2011cited by this paper
• Thermal stability of hepatitis E virus assessed by a molecular biological approach

  2011cited by this paper
• Restricted Enzooticity of Hepatitis E Virus Genotypes 1 to 4 in the United States

  2011cited by this paper
• Adaptive immune responses during acute uncomplicated and fulminant hepatitis E

  2011cited by this paper
• Hepatitis E virus infection in patients infected with the human immunodeficiency virus

  2011cited by this paper
• Hepatitis E Virus and Neurologic Disorders

  2011cited by this paper
• Treatment of chronic hepatitis E in a patient with HIV infection.

  2011cited by this paper
• Hepatitis: Hepatitis E vaccination—is HEV 239 the breakthrough?

  2011cited by this paper
• Three Amino Acid Mutations (F51L, T59A, and S390L) in the Capsid Protein of the Hepatitis E Virus Collectively Contribute to Virus Attenuation

  2011cited by this paper
• Treatment of severe acute hepatitis E by ribavirin.

  2011cited by this paper
• Factors associated with chronic hepatitis in patients with hepatitis E virus infection who have received solid organ transplants.

  2011cited by this paper
• Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus–host recombinant

  2011cited by this paper
• High viral load and deregulation of the progesterone receptor signaling pathway: association with hepatitis E-related poor pregnancy outcome.

  2011cited by this paper
• [Chronic hepatitis E in an immunocompetent patient].

  2011cited by this paper
• Hepatitis E

  2011cited by this paper
• Molecular virology of hepatitis E virus

  2011cited by this paper
• Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury.

  2011cited by this paper
• Hepatitis E virus coinfection in patients with HIV infection

  2011cited by this paper
• 1255 CHRONIC HEPATITIS E IN IMMUNOSUPPRESSED PATIENTS BEYOND LIVER- AND KIDNEY TRANSPLANTATION

  2011cited by this paper
• Effector T cells immune reactivity among patients with acute hepatitis E

  2011cited by this paper
• First Isolation of Hepatitis E Virus Genotype 4 in Europe through Swine Surveillance in the Netherlands and Belgium

  2011cited by this paper
• Standardization of Hepatitis E Virus (HEV) Nucleic Acid Amplification Technique-Based Assays: an Initial Study To Evaluate a Panel of HEV Strains and Investigate Laboratory Performance

  2011cited by this paper
• Hepatitis crónica E en paciente inmunocompetente

  2011cited by this paper
• Hepatitis E: An Emerging Infectious Disease in Germany?

  2011cited by this paper
• Chronic hepatitis E infection in children with liver transplantation

  2011cited by this paper
• Hepatitis E virus infection as a cause of graft hepatitis in liver transplant recipients

  2010cited by this paper
• Brief Communication: Case Reports of Ribavirin Treatment for Chronic Hepatitis E

  2010cited by this paper
• Pegylated interferon-alpha for treating chronic hepatitis E virus infection after liver transplantation.

  2010cited by this paper
• Serologic assays specific to immunoglobulin M antibodies against hepatitis E virus: pangenotypic evaluation of performances.

  2010cited by this paper
• Treatment of chronic hepatitis E in liver transplant recipients with pegylated interferon alpha‐2b

  2010cited by this paper
• Hepatitis E Virus‐Induced Neurological Symptoms in a Kidney‐Transplant Patient with Chronic Hepatitis

  2010cited by this paper
• Influence of Immunosuppressive Therapy on the Natural History of Genotype 3 Hepatitis-E Virus Infection After Organ Transplantation

  2010cited by this paper
• Efficacy and safety of a recombinant hepatitis E vaccine in healthy adults: a large-scale, randomised, double-blind placebo-controlled, phase 3 trial.

  2010cited by this paper
• Recent advances in Hepatitis E Virus

  2010cited by this paper
• Pig liver sausage as a source of hepatitis E virus transmission to humans.

  2010cited by this paper
• Ribavirin therapy inhibits viral replication on patients with chronic hepatitis e virus infection.

  2010cited by this paper
• Hepatitis E Outbreak on Cruise Ship

  2009cited by this paper
• Heparan Sulfate Proteoglycans Are Required for Cellular Binding of the Hepatitis E Virus ORF2 Capsid Protein and for Viral Infection

  2009cited by this paper
• Serological evidence of infection with hepatitis E virus among wild Yezo‐deer, Cervus nippon yesoensis, in Hokkaido, Japan

  2009cited by this paper
• Hepatitis E in HIV‐positive patients in a low‐endemic country

  2009cited by this paper
• Good Performance of Immunoglobulin M Assays in Diagnosing Genotype 3 Hepatitis E Virus Infections

  2009cited by this paper
• Zoonotic risk of hepatitis E virus (HEV): A study of HEV infection in animals and humans in suburbs of Beijing

  2009cited by this paper
• Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukaemia after allogeneic stem cell transplantation

  2009cited by this paper
• Persistent Carriage of Hepatitis E Virus in Patients with HIV Infection

  2009cited by this paper
• Biological and immunological characteristics of hepatitis E virus-like particles based on the crystal structure

  2009cited by this paper
• Transmission routes and risk factors for autochthonous hepatitis E virus infection in Europe: a systematic review

  2009cited by this paper
• Prevalence of hepatitis E virus infection in liver transplant recipients

  2009cited by this paper
• Epidemiology of hepatitis E in Northeastern China, South Korea and Japan.

  2009cited by this paper
• Persistent carriage of hepatitis E virus in patients with HIV infection.

  2009cited by this paper
• Lack of hepatitis E virus infection in HIV patients with advanced immunodeficiency or idiopathic liver enzyme elevations

  2009cited by this paper
• Detection of hepatitis E virus in archived German wild boar serum samples.

  2008cited by this paper
• Hepatitis E and pregnancy: understanding the pathogenesis

  2008cited by this paper
• Hepatitis E Virus Infection among Domestic Animals in Eastern China

  2008cited by this paper
• A 20‐year single‐center experience with acute liver failure during pregnancy: Is the prognosis really worse?

  2008cited by this paper
• Time trend of the prevalence of hepatitis E antibodies among farmers and blood donors: a potential zoonosis in Denmark.

  2008cited by this paper
• Hepatitis E: an emerging infection in developed countries.

  2008cited by this paper
• Hepatitis E virus: Molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention

  2008cited by this paper
• Prevalence of Hepatitis E Virus Infection in Children in the Northeast of Spain

  2008cited by this paper
• Chronic hepatitis E with cirrhosis in a kidney-transplant recipient.

  2008cited by this paper
• Hepatitis E virus and chronic hepatitis in organ-transplant recipients.

  2008cited by this paper
• Hepatitis E: an emerging awareness of an old disease.

  2008cited by this paper
• Deletions of the Hypervariable Region (HVR) in Open Reading Frame 1 of Hepatitis E Virus Do Not Abolish Virus Infectivity: Evidence for Attenuation of HVR Deletion Mutants In Vivo

  2008cited by this paper
• Use of Serological Assays for Diagnosis of Hepatitis E Virus Genotype 1 and 3 Infections in a Setting of Low Endemicity

  2007cited by this paper
• Safety and efficacy of a recombinant hepatitis E vaccine.

  2007cited by this paper
• T‐cell epitope mapping of ORF2 and ORF3 proteins of human hepatitis E virus

  2007cited by this paper
• Transfusion-associated Hepatitis E, France

  2007cited by this paper
• Transfusion‐transmitted hepatitis E in a ‘nonhyperendemic’ country

  2006cited by this paper
• Prevention of transfusion‐transmitted hepatitis E by donor‐initiated self exclusion

  2005cited by this paper
• Thermal stability of hepatitis E virus.

  2005cited by this paper
• A truncated ORF2 protein contains the most immunogenic site on ORF2: antibody responses to non-vaccine sequences following challenge of vaccinated and non-vaccinated macaques with hepatitis E virus.

  2005cited by this paper
• Hepatitis E viruses in humans and animals

  2004cited by this paper
• Transfusion‐transmitted hepatitis E caused by apparently indigenous hepatitis E virus strain in Hokkaido, Japan

  2004cited by this paper
• Zoonotic transmission of hepatitis E virus from deer to human beings.

  2003cited by this paper
• Retrospective Analysis of Blood Transfusion Recipients: Evidence for Post–Transfusion Hepatitis E

  2000cited by this paper
• Prevalence of hepatitis viruses in an anti‐human immunodeficiency virus‐positive population from Argentina. Amulticentre study

  1999cited by this paper
• Antibody to hepatitis E virus in HIV‐infected individuals and AIDS patients

  1997cited by this paper
• Isolation of a cDNA from the virus responsible for enterically transmitted non-A, non-B hepatitis.

  1990cited by this paper
• Evidence for a virus in non-A, non-B hepatitis transmitted via the fecal-oral route.

  1983cited by this paper

• Update on the molecular and cellular biology of hepatitis E virus and therapeutic opportunities.

  2026cites this paper
• Beyond the liver: the broadened tissue tropism of hepatitis E virus.

  2026cites this paper
• Clinical characteristics of hospitalized patients with hepatitis E virus infection in Poland: a multi-centre retrospective study.

  2026cites this paper
• Interferon-induced immune signatures are associated with suppression of HEV infection in porcine cell culture models

  2025cites this paper
• How hepatitis E virus invades hepatocytes: the mystery of viral entry.

  2025cites this paper
• Hepatitis E Virus in the Role of an Emerging Food-Borne Pathogen

  2025cites this paper
• Low Serological Agreement of Hepatitis E in Immunocompromised Cancer Patients: A Comparative Study of Three Anti-HEV Assays

  2025influential citation
• Turning the Spotlight on Meat-borne Viral Diseases

  2025cites this paper
• Hepatitis A and Hepatitis E Viruses Can Develop Acute Viral Hepatitis: Prevention Is the Best Policy

  2025cites this paper
• Vaccination Strategies and Research Gaps in Hepatitis E Virus for Special Populations

  2025cites this paper
• Transmission, Diagnosis, and Treatment of Acute and Chronic Hepatitis E

  2025cites this paper
• Meta-Analysis of Severe Risk Factors for Acute Hepatitis E in China

  2024cites this paper
• Colon-derived Caco-2 cells support replication of hepatitis E virus genotype 1 strain Sar55 generated by reverse genetics

  2024cites this paper
• Viral hepatitis E: Clinical manifestations, treatment, and prevention

  2024cites this paper
• Immunisation of pigs with recombinant HEV vaccines does not protect from infection with HEV genotype 3

  2024cites this paper
• Acute Hepatitis Related to Hepatitis E Virus Genotype 3f Infection in Brazil

  2024cites this paper
• Akute Virushepatitis

  2024cites this paper
• Recent advances in hepatitis E virus research and the Japanese clinical practice guidelines for hepatitis E virus infection

  2024cites this paper
• Incidence and risk factors of de novo hepatitis E virus infection after receiving liver transplantation

  2024cites this paper
• Hepatitis E outbreak in the health district of Bocaranga-Koui, Central African Republic, 2018–2019

  2024cites this paper
• Recent Advances in Protective Vaccines against Hepatitis Viruses: A Narrative Review

  2023cites this paper
• Hepatitis Virus and Hepatocellular Carcinoma: Recent Advances

  2023cites this paper
• Higher Risk of HEV Transmission and Exposure among Blood Donors in Europe and Asia in Comparison to North America: A Meta-Analysis

  2023cites this paper
• Identification of novel potential hepatitis E virus inhibitors as seen from molecular docking, free energy landscape and molecular dynamics simulation studies

  2023cites this paper
• Prophylactic Hepatitis E Vaccine.

  2023cites this paper
• Hepatitis E Virus Infections: Epidemiology, Genetic Diversity, and Clinical Considerations

  2023cites this paper
• Computational design of experimentally validated multi-epitopes vaccine against hepatitis E virus: An immunological approach

  2023cites this paper
• Detection of HEV RNA Using One-Step Real-Time RT-PCR in Farrow-to-Finish Pig Farms in Bulgaria

  2023cites this paper
• Treatment Options for Hepatitis A and E: A Non-Systematic Review

  2023cites this paper
• The Re-Emergence of Hepatitis E Virus in Europe and Vaccine Development

  2023cites this paper
• Hepatitis-E-induced cholestasis in a child: a case report

  2023cites this paper
• Epidemiology of Hepatitis E.

  2023cites this paper
• Immunization with Virus-Like Particle Vaccine Protects Rabbits against Hepatitis E-3 Virus Infection

  2022cites this paper
• Serenidad y objetividad ante la hepatitis grave infantil: el reto diagnóstico

  2022cites this paper
• Seroprevalence and burden of hepatitis E viral infection among pregnant women in central Nigeria attending antenatal clinic at a Federal Medical Centre in Central Nigeria

  2022influential citation
• Viral Interference of Hepatitis C and E Virus Replication in Novel Experimental Co-Infection Systems

  2022cites this paper
• Advanced sequencing approaches detected insertions of viral and human origin in the viral genome of chronic hepatitis E virus patients

  2022cites this paper
• Serological, Virological Investigation and Hepatic Injury Evaluation for Hepatitis E Virus in Hunting Dogs

  2022cites this paper
• Hyperspectral imaging and machine learning in food microbiology: Developments and challenges in detection of bacterial, fungal, and viral contaminants.

  2022cites this paper
• Status of anti-HEV IgG and IgM antibodies among the hemodialysis patients in southwest region of Iran

  2022cites this paper
• Hepatitis E Virus Infection in Pediatric Oncology

  2022cites this paper
• Therapeutic Advances in Viral Hepatitis A–E

  2022cites this paper
• The hepatitis E virus prevalence in autoimmune hepatitis: a systematic literature review on conducted researches

  2021cites this paper
• Increased Seroprevalence of Campylobacter jejuni , but not HEV, in healthcare workers in gastroenterological endoscopy

  2021cites this paper
• Ectopic Expression of Genotype 1 Hepatitis E Virus ORF4 Increases Genotype 3 HEV Viral Replication in Cell Culture

  2021cites this paper
• Niclosamide inhibits hepatitis E virus through suppression of NF-kappaB signalling.

  2021cites this paper
• Hepatitis E: Genotypes, strategies to prevent and manage, and the existing knowledge gaps

  2021cites this paper
• Current Paradigm of Hepatitis E Virus Among Pediatric and Adult Patients

  2021cites this paper
• Update on the management and treatment of viral hepatitis

  2021cites this paper
• The macrolide antibiotic azithromycin potently inhibits hepatitis E virus in cell culture models.

  2021cites this paper
• High prevalence of hepatitis E among regular hemodialysis patients in South of Iran

  2021cites this paper
• Hepatitis E Virus—Current Developments in Antiviral Strategies

  2021cites this paper
• Loss of antibodies to hepatitis E virus in organ transplant patients with hepatitis E

  2021cites this paper
• Assessment of subclinical effects of Hepatitis E virus infection in the United States

  2021cites this paper
• From hepatitis A to E: A critical review of viral hepatitis

  2021cites this paper
• Significant compartment‐specific impact of different RNA extraction methods and PCR assays on the sensitivity of hepatitis E virus detection

  2021cites this paper
• Anti-HEV IgG Avidity Testing: Utility for Diagnosing Acute and Resolved Genotype 3 Infections

  2021cites this paper
• Towards the Improved Accuracy of Hepatitis E Diagnosis in Vulnerable and Target Groups: A Global Perspective on the Current State of Knowledge and the Implications for Practice

  2021cites this paper
• Hepatitis E virus persists in the ejaculate of chronically infected men.

  2021cites this paper
• The impact of hepatitis E infection on hepatic fibrosis in liver transplanted patients for hepatitis C infection

  2021cites this paper
• Prognostic Significance of End-Stage Liver Diseases, Respiratory Tract Infection, and Chronic Kidney Diseases in Symptomatic Acute Hepatitis E

  2021cites this paper
• Prevalence of Toxoplasma gondii, Hepatitis E Virus and Salmonella antibodies in meat juice samples from pigs at slaughter in Switzerland.

  2021cites this paper
• Hepatitis E virus infection and rejection in kidney transplant recipients.

  2021cites this paper
• Hepatitis E virus IgG seroprevalence in liver transplant patients: A retrospective single-center experience

  2021cites this paper
• Treatment for chronic hepatitis E virus infection: A systematic review and meta‐analysis

  2020cites this paper
• Seroprevalence of hepatitis E virus in dogs in Switzerland

  2020cites this paper
• ERKRANKUNGEN DER VERDAUUNGSORGANE

  2020cites this paper
• A Nationwide Survey of Hepatitis E Virus Infection and Chronic Hepatitis in Heart and Kidney Transplant Recipients in Japan

  2020cites this paper
• Hepatitis-A- und -E-Virus-Infektionen – Altes und Neues

  2020influential citation
• Full‐length genome sequencing of RNA viruses—How the approach can enlighten us on hepatitis C and hepatitis E viruses

  2020cites this paper
• A Male Patient with Acute Hepatitis E Showing Asymptomatic and Transient Hyperthyroidism Due To Autoimmune Thyroiditis

  2020cites this paper
• Seroprevalence of hepatitis E among hospitalized patients in Slovakia: first report.

  2020cites this paper
• Clinical Characteristics of Acute Hepatitis E and Their Correlation with HEV Genotype 3 Subtypes in Italy

  2020cites this paper
• Interlaboratory Validation of a Detection Method for Hepatitis E Virus RNA in Pig Liver

  2020cites this paper
• Disseminated inflammation of the central nervous system associated with acute hepatitis E: a case report

  2020cites this paper
• Virus–Host Cell Interplay during Hepatitis E Virus Infection

  2020cites this paper
• Clinical significance of post-liver transplant hepatitis E seropositivity in high prevalence area of hepatitis E genotype 3: a prospective study

  2020cites this paper
• Hepatitis E virus infection during pregnancy

  2020cites this paper
• Risk Communication for Viral Hepatitis Management Among Migrants

  2020cites this paper
• Synthetic Peptides Containing Three Neutralizing Epitopes of Genotype 4 Swine Hepatitis E Virus ORF2 induced Protection against Swine HEV Infection in Rabbit

  2020cites this paper
• Chronic Viral Liver Diseases: Approaching the Liver Using T Cell Receptor-Mediated Gene Technologies

  2020cites this paper
• Seroprevalence of Hepatitis E Virus in liver transplant patients in Turin, Italy.

  2020cites this paper
• Clinical Manifestations, Pathogenesis and Treatment of Hepatitis E Virus Infections

  2020cites this paper
• Robust hepatitis E virus infection and transcriptional response in human hepatocytes

  2020cites this paper
• Epidemiology, diagnosis, vaccines, and bibliometric analysis of the 100 top-cited studies on Hepatitis E virus

  2020cites this paper
• Hepatitis-A- und -E-Virus-Infektionen – Altes und Neues

  2020influential citation
• Hepatitis E

  2020cites this paper
• Defining Virus-specific CD8+ TCR Repertoires for Therapeutic Regeneration of T Cells against Chronic Hepatitis E.

  2019cites this paper
• Cell culture systems for the study of hepatitis E virus

  2019cites this paper
• Acute and Persistent Hepatitis E Virus Genotype 3 and 4 Infection: Clinical Features, Pathogenesis, and Treatment.

  2019cites this paper
• Chronic Hepatitis E is associated with cholangitis

  2019cites this paper
• The Clinical Perspective on Hepatitis E

  2019influential citation
• Study of hepatitis E virus ORF2 antigen kinetics in human-liver chimeric mice and its impact on HEV diagnosis

  2019cites this paper
• Whole blood based cytokine release assay assesses cellular immunity in hepatitis E resolver patients

  2019cites this paper
• Infección del virus de la hepatitis E en mujeres embarazadas

  2019cites this paper
• Seroprevalence and Characteristics of Hepatitis E in the United States A dissertation submitted to the faculty of the University of Minnesota by Christopher Campbell In fulfillment of requirements for the degree of Doctor of Philosophy

  2019cites this paper
• Haematological, serum biochemical and histopathological changes in hepatitis E virus seropositive pigs in Ibadan, Nigeria

  2019cites this paper
• Study of hepatitis E virus ORF2 antigen kinetics in human-liver chimeric mice and its impact on HEV diagnosis.

  2019cites this paper
• Establishment of a Highly Sensitive Assay for Detection of Hepatitis E Virus-Specific Immunoglobulins

  2019cites this paper
• Updates in Hepatitis E virus (HEV) field; lessons learned from human liver chimeric mice

  2019cites this paper