Lipid metabolism in Chlamydia trachomatis-infected cells: directed trafficking of Golgi-derived sphingolipids to the chlamydial inclusion.

No abstract is available for this paper.

• Publication year

  1995

• Venue

  Proceedings of the National Academy of Sciences of the United States of America

• Publication date

  1995-05-23

• Fields of study

  Biology, Medicine

• Identifiers
  DOI 10.1073/PNAS.92.11.4877PMID 7761416PMCID PMC41810
• External record

  Open on Semantic Scholar

• Source metadata

  Semantic Scholar, PubMed

• No claims are published for this paper.

• No concepts are published for this paper.

• Cloning and characterization of a Chlamydia psittaci gene coding for a protein localized in the inclusion membrane of infected cells

  1995cited by this paper
• Mechanism of C. trachomatis attachment to eukaryotic host cells.

  1992cited by this paper
• Brefeldin A: insights into the control of membrane traffic and organelle structure

  1992cited by this paper
• The interaction of bacteria with mammalian cells.

  1992cited by this paper
• Glycosaminoglycans: molecular properties, protein interactions, and role in physiological processes.

  1991cited by this paper
• Interaction of chlamydiae and host cells in vitro.

  1991cited by this paper
• In situ studies on incorporation of nucleic acid precursors into Chlamydia trachomatis DNA

  1991cited by this paper
• Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus.

  1990cited by this paper
• Lipid traffic in eukaryotic cells: mechanisms for intracellular transport and organelle-specific enrichment of lipids.

  1990cited by this paper
• Fusion of inclusions following superinfection of HeLa cells by two serovars of Chlamydia trachomatis

  1989cited by this paper
• Molecular trapping of a fluorescent ceramide analogue at the Golgi apparatus of fixed cells: interaction with endogenous lipids provides a trans-Golgi marker for both light and electron microscopy

  1989cited by this paper
• A series of fluorescent N-acylsphingosines: synthesis, physical properties, and studies in cultured cells.

  1988cited by this paper
• Novel blockade by brefeldin A of intracellular transport of secretory proteins in cultured rat hepatocytes.

  1986cited by this paper
• A vital stain for the Golgi apparatus.

  1985cited by this paper
• Intracellular translocation of fluorescent sphingolipids in cultured fibroblasts: endogenously synthesized sphingomyelin and glucocerebroside analogues pass through the Golgi apparatus en route to the plasma membrane

  1985cited by this paper
• Comparative biology of intracellular parasitism.

  1985cited by this paper
• Lysosomal response of a murine macrophage-like cell line persistently infected with Coxiella burnetii

  1983cited by this paper
• Biochemical stratagem for obligate parasitism of eukaryotic cells by Coxiella burnetii.

  1981cited by this paper
• Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis

  1981cited by this paper
• Inhibition of phagolysosome fusion is localized to Chlamydia psittaci-laden vacuoles

  1981cited by this paper
• Utilization of L-cell nucleoside triphosphates by Chlamydia psittaci for ribonucleic acid synthesis

  1975cited by this paper
• Competition between Chlamydia psittaci and L cells for host isoleucine pools: a limiting factor in chlamydial multiplication

  1975cited by this paper
• Availability of Bases and Nucleosides as Precursors of Nucleic Acids in L Cells and in the Agent of Meningopneumonitis

  1966cited by this paper
• The titration of trachoma and inclusion blennorrhoea viruses in cell cultures.

  1960cited by this paper
• A rapid method of total lipid extraction and purification.

  1959cited by this paper

• Bacterial Toxin Exploits Host Membrane Phospholipid as a Receptor for Binding, Entry, and Cytopathogenicity

  2026cites this paper
• More than just membranes: membrane contact sites as crossroads for infections.

  2025cites this paper
• Endoplasmic reticulum: the target of chlamydial manipulation

  2025cites this paper
• Genome-wide identification of modulators of Chlamydia trachomatis parasitophorous vacuole stability highlights an important role for sphingolipid supply

  2025cites this paper
• Trifunctional sphingomyelin derivatives enable nanoscale resolution of sphingomyelin turnover in physiological and infection processes via expansion microscopy

  2024cites this paper
• Combination of compound screening with an animal model identifies pentamidine to prevent Chlamydia trachomatis infection

  2024cites this paper
• Specialized contact sites regulate the fusion of chlamydial inclusion membranes

  2024cites this paper
• Organelles are miscommunicating: Membrane contact sites getting hijacked by pathogens

  2023cites this paper
• Pathogenic NKT cells attenuate urogenital chlamydial clearance and enhance infertility

  2023cites this paper
• Requirement of GrgA for Chlamydia infectious progeny production, optimal growth, and efficient plasmid maintenance

  2023cites this paper
• Establishing the intracellular niche of obligate intracellular vacuolar pathogens

  2023cites this paper
• Chlamydia trachomatis inhibits apoptosis in infected cells by targeting the pro-apoptotic proteins Bax and Bak

  2022cites this paper
• Differential Effects of Small Molecule Inhibitors on the Intracellular Chlamydia Infection

  2022cites this paper
• Chlamydial Infection-Dependent Synthesis of Sphingomyelin as a Novel Anti-Chlamydial Target of Ceramide Mimetic Compounds

  2022cites this paper
• Got mutants? How advances in chlamydial genetics have furthered the study of effector proteins

  2021cites this paper
• The role of membrane contact sites at the bacteria-host interface

  2021cites this paper
• The Small Molecule H89 Inhibits Chlamydia Inclusion Growth and Production of Infectious Progeny

  2021cites this paper
• Lipid larceny: channelizing host lipids for establishing successful pathogenesis by bacteria

  2020cites this paper
• Chlamydia

  2020cites this paper
• Sexually Transmitted Infections in Adolescence and Young Adulthood: A Practical Guide for Clinicians

  2020cites this paper
• Markerless Gene Deletion by Floxed Cassette Allelic Exchange Mutagenesis in Chlamydia trachomatis.

  2020cites this paper
• Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion

  2020cites this paper
• Penicillin-binding proteins regulate multiple steps in the polarized cell division process of Chlamydia

  2020cites this paper
• Regulation of Mucosal Immunity in the Genital Tract: Balancing Reproduction and Protective Immunity

  2020cites this paper
• Host membrane lipids are trafficked to membranes of intravacuolar bacterium Ehrlichia chaffeensis

  2020cites this paper
• Depletion of SNAP-23 and Syntaxin 4 alters lipid droplet homeostasis during Chlamydia infection

  2019cites this paper
• Proximity Labeling To Map Host-Pathogen Interactions at the Membrane of a Bacterium-Containing Vacuole in Chlamydia trachomatis-Infected Human Cells

  2019cites this paper
• Chlamydia trachomatis‐infected human cells convert ceramide to sphingomyelin without sphingomyelin synthases 1 and 2

  2019cites this paper
• Make It a Sweet Home: Responses of Chlamydia trachomatis to the Challenges of an Intravacuolar Lifestyle

  2019cites this paper
• The STING pathway in response to chlamydial infection.

  2019cites this paper
• Sphingolipid Metabolism and Transport in Chlamydia trachomatis and Chlamydia psittaci Infections

  2019cites this paper
• Diverse Facets of Sphingolipid Involvement in Bacterial Infections

  2019cites this paper
• Chlamydial Infection From Outside to Inside

  2019cites this paper
• The multiple functions of the numerous Chlamydia trachomatis secreted proteins: the tip of the iceberg

  2019cites this paper
• Akt/AS160 Signaling Pathway Inhibition Impairs Infection by Decreasing Rab14-Controlled Sphingolipids Delivery to Chlamydial Inclusions

  2019cites this paper
• Targeting host lipid flows: Exploring new antiviral and antibiotic strategies

  2019cites this paper
• A predation assay using amoebae to screen for virulence factors unearthed the first W. chondrophila inclusion membrane protein

  2019cites this paper
• Isolation and Propagation of Single Inclusion-Derived Chlamydia Using Laser Microdissection.

  2019cites this paper
• Tiny architects: biogenesis of intracellular replicative niches by bacterial pathogens.

  2018cites this paper
• Cross-kingdom lipid transfer in arbuscular mycorrhiza symbiosis and beyond.

  2018cites this paper
• Chlamydia trachomatis regulates growth and development in response to host cell fatty acid availability in the absence of lipid droplets

  2018cites this paper
• Chlamydia Trachomatis Urogenital Infections

  2018cites this paper
• The role of acid sphingomyelinase and modulation of sphingolipid metabolism in bacterial infection

  2018cites this paper
• Proximity-dependent proteomics of the Chlamydia trachomatis inclusion membrane reveals functional interactions with endoplasmic reticulum exit sites

  2018cites this paper
• Therapeutic Targets in Chlamydial Fatty Acid and Phospholipid Synthesis

  2018cites this paper
• Peptidase Inhibitor 15 (PI15) Regulates Chlamydial CPAF Activity

  2018cites this paper
• Lipid metabolism and intracellular bacterial virulence: key to next-generation therapeutics.

  2018cites this paper
• IncV, a FFAT motif-containing Chlamydia protein, tethers the endoplasmic reticulum to the pathogen-containing vacuole

  2017cites this paper
• Chlamydia trachomatis Is Responsible for Lipid Vacuolation in the Amniotic Epithelium of Fetal Gastroschisis.

  2017influential citation
• The role of host cell organelles in the development of Simkania negevensis.

  2017cites this paper
• Manipulation of Host Cholesterol by Obligate Intracellular Bacteria

  2017cites this paper
• Laser microdissection: A promising tool for exploring microorganisms and their interactions with hosts.

  2017cites this paper
• Characterization of the Growth of Chlamydia trachomatis in In Vitro-Generated Stratified Epithelium

  2017cites this paper
• Contribution of the Exit Mechanism Extrusion in Chlamydia trachomatis Pathogenesis

  2017cites this paper
• Development of a Proximity Labeling System to Map the Chlamydia trachomatis Inclusion Membrane

  2017influential citation
• The cellular ceramide transport protein CERT promotes Chlamydia psittaci infection and controls bacterial sphingolipid uptake

  2017cites this paper
• Interactions between the Coxiella burnetii parasitophorous vacuole and the endoplasmic reticulum involve the host protein ORP1L

  2017cites this paper
• Insights into the interaction of Enterococcus faecalis with host cells

  2017cites this paper
• Orchestration of the mammalian host cell glucose transporter proteins-1 and 3 by Chlamydia contributes to intracellular growth and infectivity

  2017cites this paper
• The development of a stratified keratinocyte model for chlamydia trachomatis pathogenesis studies.

  2017cites this paper
• Hijacking of Membrane Contact Sites by Intracellular Bacterial Pathogens.

  2017cites this paper
• Chlamydia trachomatis utilizes the mammalian CLA1 lipid transporter to acquire host phosphatidylcholine essential for growth

  2016influential citation
• Chlamydia trachomatis growth and development requires the activity of host Long-chain Acyl-CoA Synthetases (ACSLs)

  2016cites this paper
• Subversion of Retrograde Trafficking by Translocated Pathogen Effectors.

  2016cites this paper
• Guinea pig genital tract lipidome reveals in vivo and in vitro regulation of phosphatidylcholine 16:0/18:1 and contribution to Chlamydia trachomatis serovar D infectivity

  2016cites this paper
• Manipulation of host nuclear function by Chlamydia trachomatis

  2016cites this paper
• Polarized Cell Division of Chlamydia trachomatis

  2016cites this paper
• Chlamydia trachomatis Inclusion Disrupts Host Cell Cytokinesis to Enhance Its Growth in Multinuclear Cells

  2016cites this paper
• The Making and Taking of Lipids: The Role of Bacterial Lipid Synthesis and the Harnessing of Host Lipids in Bacterial Pathogenesis.

  2016cites this paper
• Interaction of Chlamydiae with human macrophages

  2016cites this paper
• Sortilin is associated with the chlamydial inclusion and is modulated during infection

  2016cites this paper
• Proteomic analysis of the Simkania‐containing vacuole: the central role of retrograde transport

  2016influential citation
• MASTERARBEIT / MASTER’S THESIS

  2016cites this paper
• Contrasting Lifestyles Within the Host Cell

  2016cites this paper
• Manipulation of the Host Cell Cytoskeleton by Chlamydia.

  2016cites this paper
• Anaplasma phagocytophilum Rab10‐dependent parasitism of the trans‐Golgi network is critical for completion of the infection cycle

  2016cites this paper
• Chlamydial infertility in women: Diagnosis, epidemiology and immune response

  2016cites this paper
• Danger signals, inflammasomes, and the intricate intracellular lives of chlamydiae

  2016cites this paper
• Using Fluorescent Proteins to Visualize and Quantitate Chlamydia Vacuole Growth Dynamics in Living Cells.

  2015cites this paper
• Chlamydia trachomatis Infection Leads to Defined Alterations to the Lipid Droplet Proteome in Epithelial Cells

  2015cites this paper
• Differential Translocation of Host Cellular Materials into the Chlamydia trachomatis Inclusion Lumen during Chemical Fixation

  2015cites this paper
• Hijacking and Use of Host Lipids by Intracellular Pathogens

  2015cites this paper
• Trafficking of Estrella lausannensis in human macrophages.

  2015cites this paper
• Enzymatic characterization of Chlamydophila pneumoniae phospholipase D.

  2015cites this paper
• The trans-Golgi SNARE syntaxin 10 is required for optimal development of Chlamydia trachomatis

  2015cites this paper
• Remodeling of host phosphatidylcholine by Chlamydia acyltransferase is regulated by acyl-CoA binding protein ACBD6 associated with lipid droplets

  2015influential citation
• Chlamydia psittaci: update on an underestimated zoonotic agent.

  2015cites this paper
• STIM1 Is a Novel Component of ER-Chlamydia trachomatis Inclusion Membrane Contact Sites

  2015cites this paper
• Chlamydia trachomatis Relies on Autonomous Phospholipid Synthesis for Membrane Biogenesis*♦

  2015cites this paper
• Fluorescent labeling reliably identifies Chlamydia trachomatis in living human endometrial cells and rapidly and accurately quantifies chlamydial inclusion forming units.

  2015cites this paper
• Neospora caninum Recruits Host Cell Structures to Its Parasitophorous Vacuole and Salvages Lipids from Organelles

  2015cites this paper
• C. pneumoniae disrupts eNOS trafficking and impairs NO production in human aortic endothelial cells

  2015cites this paper
• Determination of the effect of JO146, a CtHtrA inhibitor, on the chlamydial developmental cycle and persistence

  2015cites this paper
• Production and characterisation of putative early effector proteins in Chlamydia trachomatis infection

  2015cites this paper
• NBD C6‐ceramide

  2015cites this paper
• Chlamydia abortus: New Aspects of Infectious Abortion in Sheep and Potential Risk for Pregnant Women

  2015cites this paper
• A series of ceramide analogs modified at the 1-position with potent activity against the intracellular growth of Chlamydia trachomatis.

  2015cites this paper
• Chlamydial Lytic Exit from Host Cells Is Plasmid Regulated

  2015cites this paper
• In Contrast to Chlamydia trachomatis, Waddlia chondrophila Grows in Human Cells without Inhibiting Apoptosis, Fragmenting the Golgi Apparatus, or Diverting Post-Golgi Sphingomyelin Transport

  2015cites this paper
• Sphingolipid Metabolism and Interorganellar Transport: Localization of Sphingolipid Enzymes and Lipid Transfer Proteins

  2015cites this paper